Application of a liquid chromatographic/tandem mass spectrometric method to a urinary excretion study of rabeprazole and two of its metabolites in healthy human urine
• We develop a LC–MS/MS method for quantification of rabeprazole and its metabolites. • The fully validated assay is applied to urine excretion study of rabeprazole in healthy volunteers. • Rabeprazole stock solutions are stable if dissolved in methanol containing 0.5‰ DEA. • Rabeprazole and its two...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Lu, Chengtao [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2015 |
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| Schlagwörter: |
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| Umfang: |
6 |
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| Übergeordnetes Werk: |
Enthalten in: Brain microstructure and morphology of very preterm-born infants at term equivalent age: Associations with motor and cognitive outcomes at 1 and 2 years - Pannek, Kerstin ELSEVIER, 2020, New York, NY [u.a.] |
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| Übergeordnetes Werk: |
volume:988 ; year:2015 ; day:15 ; month:04 ; pages:75-80 ; extent:6 |
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| DOI / URN: |
10.1016/j.jchromb.2015.01.023 |
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Enthalten in Brain microstructure and morphology of very preterm-born infants at term equivalent age: Associations with motor and cognitive outcomes at 1 and 2 years New York, NY [u.a.] volume:988 year:2015 day:15 month:04 pages:75-80 extent:6 |
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Application of a liquid chromatographic/tandem mass spectrometric method to a urinary excretion study of rabeprazole and two of its metabolites in healthy human urine |
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Application of a liquid chromatographic/tandem mass spectrometric method to a urinary excretion study of rabeprazole and two of its metabolites in healthy human urine |
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Lu, Chengtao |
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Brain microstructure and morphology of very preterm-born infants at term equivalent age: Associations with motor and cognitive outcomes at 1 and 2 years |
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Brain microstructure and morphology of very preterm-born infants at term equivalent age: Associations with motor and cognitive outcomes at 1 and 2 years |
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Lu, Chengtao |
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Lu, Chengtao |
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10.1016/j.jchromb.2015.01.023 |
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540 610 |
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application of a liquid chromatographic/tandem mass spectrometric method to a urinary excretion study of rabeprazole and two of its metabolites in healthy human urine |
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Application of a liquid chromatographic/tandem mass spectrometric method to a urinary excretion study of rabeprazole and two of its metabolites in healthy human urine |
| abstract |
• We develop a LC–MS/MS method for quantification of rabeprazole and its metabolites. • The fully validated assay is applied to urine excretion study of rabeprazole in healthy volunteers. • Rabeprazole stock solutions are stable if dissolved in methanol containing 0.5‰ DEA. • Rabeprazole and its two metabolites undergo nearly non-renal elimination in human. |
| abstractGer |
• We develop a LC–MS/MS method for quantification of rabeprazole and its metabolites. • The fully validated assay is applied to urine excretion study of rabeprazole in healthy volunteers. • Rabeprazole stock solutions are stable if dissolved in methanol containing 0.5‰ DEA. • Rabeprazole and its two metabolites undergo nearly non-renal elimination in human. |
| abstract_unstemmed |
• We develop a LC–MS/MS method for quantification of rabeprazole and its metabolites. • The fully validated assay is applied to urine excretion study of rabeprazole in healthy volunteers. • Rabeprazole stock solutions are stable if dissolved in methanol containing 0.5‰ DEA. • Rabeprazole and its two metabolites undergo nearly non-renal elimination in human. |
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Application of a liquid chromatographic/tandem mass spectrometric method to a urinary excretion study of rabeprazole and two of its metabolites in healthy human urine |
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https://doi.org/10.1016/j.jchromb.2015.01.023 |
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Jia, Yanyan Song, Ying Li, Xueqing Sun, Yuan Zhao, Jinyi Wang, Shan Shi, Lei Wen, Aidong Ding, Li |
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Jia, Yanyan Song, Ying Li, Xueqing Sun, Yuan Zhao, Jinyi Wang, Shan Shi, Lei Wen, Aidong Ding, Li |
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