Development and validation of a HPLC–MS/MS method for the determination of phytolaccagenin in rat plasma and application to a pharmacokinetic study
Highlights • A novel validated LC–MS/MS method for the quantification of hESA in rat plasma. • The hESA shows large volume of distribution in rats. • The hESA is rapidly eliminated from systemic circulation in rats.
Gespeichert in:
| Autor*in: |
Wei, Fenghuan [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2015 |
|---|
| Schlagwörter: |
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| Umfang: |
7 |
|---|
| Übergeordnetes Werk: |
Enthalten in: Monitoring the changes in physicochemical, sensory properties and microbiota of village-type homemade yoghurts along three consecutive back-slopping procedures - Gölbaşι, Gülcan ELSEVIER, 2023, the official analytical journal of the American Association of Pharmaceutical Scientists, New York, NY [u.a.] |
|---|---|
| Übergeordnetes Werk: |
volume:107 ; year:2015 ; day:25 ; month:03 ; pages:82-88 ; extent:7 |
| Links: |
|---|
| DOI / URN: |
10.1016/j.jpba.2014.12.025 |
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Development and validation of a HPLC–MS/MS method for the determination of phytolaccagenin in rat plasma and application to a pharmacokinetic study |
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Highlights • A novel validated LC–MS/MS method for the quantification of hESA in rat plasma. • The hESA shows large volume of distribution in rats. • The hESA is rapidly eliminated from systemic circulation in rats. |
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Development and validation of a HPLC–MS/MS method for the determination of phytolaccagenin in rat plasma and application to a pharmacokinetic study |
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https://doi.org/10.1016/j.jpba.2014.12.025 |
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Singh, Ravi Shankar Prasad Fueth, Matthias Swarts, Steven Okunieff, Paul Derendorf, Hartmut |
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Singh, Ravi Shankar Prasad Fueth, Matthias Swarts, Steven Okunieff, Paul Derendorf, Hartmut |
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| doi_str |
10.1016/j.jpba.2014.12.025 |
| up_date |
2024-07-06T20:19:43.547Z |
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