The kynurenine to tryptophan ratio as a prognostic tool for glioblastoma patients enrolling in immunotherapy

• We discuss the complex link between indoleamine 2,3 dioxygenase 1 (IDO1), tryptophan (Trp) and kynurenine (Kyn) in glioblastoma (GBM) patients. • We identify a potential new prognostic tool for GBM patient stratification. • We found that differences in the Kyn/Trp ratio appear ⩾10weeks post-surger...
Ausführliche Beschreibung

Gespeichert in:
Autor*in:

Zhai, Lijie [verfasserIn]

Dey, Mahua

Lauing, Kristen L.

Gritsina, Galina

Kaur, Rajwant

Lukas, Rimas V.

Nicholas, M. Kelly

Rademaker, Alfred W.

Dostal, Carlos R.

McCusker, Robert H.

Raizer, Jeffrey J.

Parsa, Andrew T.

Bloch, Orin

Wainwright, Derek A.

Format:

E-Artikel

Sprache:

Englisch

Erschienen:

2015

Schlagwörter:

Brain tumor

Immunosuppression

Kynurenine

Tryptophan

Diagnostic

Metabolism

Glioblastoma multiforme

Umfang:

5

Übergeordnetes Werk:

Enthalten in: New trends of new psychoactive substances (NPS)-infused chocolate: Identification and quantification of trace level of NPS in complex matrix by GC-MS and NMR - Song, Chun-hui ELSEVIER, 2023, Burlington, Mass

Übergeordnetes Werk:

volume:22 ; year:2015 ; number:12 ; pages:1964-1968 ; extent:5

Links:

Volltext

DOI / URN:

10.1016/j.jocn.2015.06.018

Katalog-ID:

ELV029119502

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