Hypoxia inducible factor 1α down regulates cell surface expression of α1,2-fucosylated glycans in human pancreatic adenocarcinoma cells
• PDAC and colon cancer (CRC) cell lines constitutively express HIF-1α. • HIF-1α inhibition enhances cell surface α1,2-fucosylation on PDAC and CRC cells. • Inhibition of HIF-1α enhances FUT1 and FUT2 transcripts in PDAC and CRC cells. • Knock down of HIF-1α increases FUT1/2 expression and α1,2-fuco...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Belo, Ana I. [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2015 |
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| Schlagwörter: |
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| Umfang: |
8 |
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| Übergeordnetes Werk: |
Enthalten in: Mitigating the environmental impacts of milk production via anaerobic digestion of manure: Case study of a dairy farm in the Po Valley - Battini, F. ELSEVIER, 2014, for the rapid publication of short reports in biochemistry, biophysics, and molecular biology, Chichester |
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| Übergeordnetes Werk: |
volume:589 ; year:2015 ; number:18 ; day:19 ; month:08 ; pages:2359-2366 ; extent:8 |
| Links: |
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| DOI / URN: |
10.1016/j.febslet.2015.07.035 |
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10.1016/j.febslet.2015.07.035 doi GBVA2015021000012.pica (DE-627)ELV02930542X (ELSEVIER)S0014-5793(15)00660-2 DE-627 ger DE-627 rakwb eng 570 530 610 570 DE-600 530 DE-600 610 DE-600 333.7 VZ 610 VZ 630 640 610 VZ Belo, Ana I. verfasserin aut Hypoxia inducible factor 1α down regulates cell surface expression of α1,2-fucosylated glycans in human pancreatic adenocarcinoma cells 2015 8 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier • PDAC and colon cancer (CRC) cell lines constitutively express HIF-1α. • HIF-1α inhibition enhances cell surface α1,2-fucosylation on PDAC and CRC cells. • Inhibition of HIF-1α enhances FUT1 and FUT2 transcripts in PDAC and CRC cells. • Knock down of HIF-1α increases FUT1/2 expression and α1,2-fucosylation in PaTu-T. • HIF-1α suppresses FUT1/2 expression, thus regulating cell surface α1,2-fucosylation. RT Elsevier HIF Elsevier BG Elsevier Ley Elsevier HRP Elsevier ARNT Elsevier iRNA Elsevier Lex Elsevier PDAC Elsevier PC Elsevier Abs Elsevier KD Elsevier PaTu-S Elsevier HRE Elsevier UEA-1 Elsevier PaTu-T Elsevier van Vliet, Sandra J. oth Maus, Andreas oth Laan, Lisa C. oth Nauta, Tessa D. oth Koolwijk, Pieter oth Tefsen, Boris oth van Die, Irma oth Enthalten in Wiley Battini, F. ELSEVIER Mitigating the environmental impacts of milk production via anaerobic digestion of manure: Case study of a dairy farm in the Po Valley 2014 for the rapid publication of short reports in biochemistry, biophysics, and molecular biology Chichester (DE-627)ELV012686999 volume:589 year:2015 number:18 day:19 month:08 pages:2359-2366 extent:8 https://doi.org/10.1016/j.febslet.2015.07.035 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA AR 589 2015 18 19 0819 2359-2366 8 045F 570 |
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10.1016/j.febslet.2015.07.035 doi GBVA2015021000012.pica (DE-627)ELV02930542X (ELSEVIER)S0014-5793(15)00660-2 DE-627 ger DE-627 rakwb eng 570 530 610 570 DE-600 530 DE-600 610 DE-600 333.7 VZ 610 VZ 630 640 610 VZ Belo, Ana I. verfasserin aut Hypoxia inducible factor 1α down regulates cell surface expression of α1,2-fucosylated glycans in human pancreatic adenocarcinoma cells 2015 8 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier • PDAC and colon cancer (CRC) cell lines constitutively express HIF-1α. • HIF-1α inhibition enhances cell surface α1,2-fucosylation on PDAC and CRC cells. • Inhibition of HIF-1α enhances FUT1 and FUT2 transcripts in PDAC and CRC cells. • Knock down of HIF-1α increases FUT1/2 expression and α1,2-fucosylation in PaTu-T. • HIF-1α suppresses FUT1/2 expression, thus regulating cell surface α1,2-fucosylation. RT Elsevier HIF Elsevier BG Elsevier Ley Elsevier HRP Elsevier ARNT Elsevier iRNA Elsevier Lex Elsevier PDAC Elsevier PC Elsevier Abs Elsevier KD Elsevier PaTu-S Elsevier HRE Elsevier UEA-1 Elsevier PaTu-T Elsevier van Vliet, Sandra J. oth Maus, Andreas oth Laan, Lisa C. oth Nauta, Tessa D. oth Koolwijk, Pieter oth Tefsen, Boris oth van Die, Irma oth Enthalten in Wiley Battini, F. ELSEVIER Mitigating the environmental impacts of milk production via anaerobic digestion of manure: Case study of a dairy farm in the Po Valley 2014 for the rapid publication of short reports in biochemistry, biophysics, and molecular biology Chichester (DE-627)ELV012686999 volume:589 year:2015 number:18 day:19 month:08 pages:2359-2366 extent:8 https://doi.org/10.1016/j.febslet.2015.07.035 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA AR 589 2015 18 19 0819 2359-2366 8 045F 570 |
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10.1016/j.febslet.2015.07.035 doi GBVA2015021000012.pica (DE-627)ELV02930542X (ELSEVIER)S0014-5793(15)00660-2 DE-627 ger DE-627 rakwb eng 570 530 610 570 DE-600 530 DE-600 610 DE-600 333.7 VZ 610 VZ 630 640 610 VZ Belo, Ana I. verfasserin aut Hypoxia inducible factor 1α down regulates cell surface expression of α1,2-fucosylated glycans in human pancreatic adenocarcinoma cells 2015 8 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier • PDAC and colon cancer (CRC) cell lines constitutively express HIF-1α. • HIF-1α inhibition enhances cell surface α1,2-fucosylation on PDAC and CRC cells. • Inhibition of HIF-1α enhances FUT1 and FUT2 transcripts in PDAC and CRC cells. • Knock down of HIF-1α increases FUT1/2 expression and α1,2-fucosylation in PaTu-T. • HIF-1α suppresses FUT1/2 expression, thus regulating cell surface α1,2-fucosylation. RT Elsevier HIF Elsevier BG Elsevier Ley Elsevier HRP Elsevier ARNT Elsevier iRNA Elsevier Lex Elsevier PDAC Elsevier PC Elsevier Abs Elsevier KD Elsevier PaTu-S Elsevier HRE Elsevier UEA-1 Elsevier PaTu-T Elsevier van Vliet, Sandra J. oth Maus, Andreas oth Laan, Lisa C. oth Nauta, Tessa D. oth Koolwijk, Pieter oth Tefsen, Boris oth van Die, Irma oth Enthalten in Wiley Battini, F. ELSEVIER Mitigating the environmental impacts of milk production via anaerobic digestion of manure: Case study of a dairy farm in the Po Valley 2014 for the rapid publication of short reports in biochemistry, biophysics, and molecular biology Chichester (DE-627)ELV012686999 volume:589 year:2015 number:18 day:19 month:08 pages:2359-2366 extent:8 https://doi.org/10.1016/j.febslet.2015.07.035 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA AR 589 2015 18 19 0819 2359-2366 8 045F 570 |
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10.1016/j.febslet.2015.07.035 doi GBVA2015021000012.pica (DE-627)ELV02930542X (ELSEVIER)S0014-5793(15)00660-2 DE-627 ger DE-627 rakwb eng 570 530 610 570 DE-600 530 DE-600 610 DE-600 333.7 VZ 610 VZ 630 640 610 VZ Belo, Ana I. verfasserin aut Hypoxia inducible factor 1α down regulates cell surface expression of α1,2-fucosylated glycans in human pancreatic adenocarcinoma cells 2015 8 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier • PDAC and colon cancer (CRC) cell lines constitutively express HIF-1α. • HIF-1α inhibition enhances cell surface α1,2-fucosylation on PDAC and CRC cells. • Inhibition of HIF-1α enhances FUT1 and FUT2 transcripts in PDAC and CRC cells. • Knock down of HIF-1α increases FUT1/2 expression and α1,2-fucosylation in PaTu-T. • HIF-1α suppresses FUT1/2 expression, thus regulating cell surface α1,2-fucosylation. RT Elsevier HIF Elsevier BG Elsevier Ley Elsevier HRP Elsevier ARNT Elsevier iRNA Elsevier Lex Elsevier PDAC Elsevier PC Elsevier Abs Elsevier KD Elsevier PaTu-S Elsevier HRE Elsevier UEA-1 Elsevier PaTu-T Elsevier van Vliet, Sandra J. oth Maus, Andreas oth Laan, Lisa C. oth Nauta, Tessa D. oth Koolwijk, Pieter oth Tefsen, Boris oth van Die, Irma oth Enthalten in Wiley Battini, F. ELSEVIER Mitigating the environmental impacts of milk production via anaerobic digestion of manure: Case study of a dairy farm in the Po Valley 2014 for the rapid publication of short reports in biochemistry, biophysics, and molecular biology Chichester (DE-627)ELV012686999 volume:589 year:2015 number:18 day:19 month:08 pages:2359-2366 extent:8 https://doi.org/10.1016/j.febslet.2015.07.035 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA AR 589 2015 18 19 0819 2359-2366 8 045F 570 |
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hypoxia inducible factor 1α down regulates cell surface expression of α1,2-fucosylated glycans in human pancreatic adenocarcinoma cells |
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Hypoxia inducible factor 1α down regulates cell surface expression of α1,2-fucosylated glycans in human pancreatic adenocarcinoma cells |
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• PDAC and colon cancer (CRC) cell lines constitutively express HIF-1α. • HIF-1α inhibition enhances cell surface α1,2-fucosylation on PDAC and CRC cells. • Inhibition of HIF-1α enhances FUT1 and FUT2 transcripts in PDAC and CRC cells. • Knock down of HIF-1α increases FUT1/2 expression and α1,2-fucosylation in PaTu-T. • HIF-1α suppresses FUT1/2 expression, thus regulating cell surface α1,2-fucosylation. |
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• PDAC and colon cancer (CRC) cell lines constitutively express HIF-1α. • HIF-1α inhibition enhances cell surface α1,2-fucosylation on PDAC and CRC cells. • Inhibition of HIF-1α enhances FUT1 and FUT2 transcripts in PDAC and CRC cells. • Knock down of HIF-1α increases FUT1/2 expression and α1,2-fucosylation in PaTu-T. • HIF-1α suppresses FUT1/2 expression, thus regulating cell surface α1,2-fucosylation. |
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• PDAC and colon cancer (CRC) cell lines constitutively express HIF-1α. • HIF-1α inhibition enhances cell surface α1,2-fucosylation on PDAC and CRC cells. • Inhibition of HIF-1α enhances FUT1 and FUT2 transcripts in PDAC and CRC cells. • Knock down of HIF-1α increases FUT1/2 expression and α1,2-fucosylation in PaTu-T. • HIF-1α suppresses FUT1/2 expression, thus regulating cell surface α1,2-fucosylation. |
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Hypoxia inducible factor 1α down regulates cell surface expression of α1,2-fucosylated glycans in human pancreatic adenocarcinoma cells |
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