Ultrafast separation of fluorinated and desfluorinated pharmaceuticals using highly efficient and selective chiral selectors bonded to superficially porous particles
• Ultrafast separations of fluorinated drugs from corresponding desfluoro impurities. • Macrocyclic chiral selectors bonded to superficially porous particles were tested. • The chiral phases showed enhanced selectivity compared to other achiral phases. • HPLC-ESI-MS compatibility was demonstrated. •...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Barhate, Chandan L. [verfasserIn] |
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E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2015 |
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| Schlagwörter: |
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| Umfang: |
7 |
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| Übergeordnetes Werk: |
Enthalten in: Defense development: The role of co-creation in filling the gap between policy-makers and technology development - Liwång, Hans ELSEVIER, 2022, including electrophoresis, mass spectrometry and other separation and detection methods, New York, NY [u.a.] |
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| Übergeordnetes Werk: |
volume:1426 ; year:2015 ; day:24 ; month:12 ; pages:241-247 ; extent:7 |
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| DOI / URN: |
10.1016/j.chroma.2015.11.056 |
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| 520 | |a • Ultrafast separations of fluorinated drugs from corresponding desfluoro impurities. • Macrocyclic chiral selectors bonded to superficially porous particles were tested. • The chiral phases showed enhanced selectivity compared to other achiral phases. • HPLC-ESI-MS compatibility was demonstrated. • All separations are carried out under isocratic conditions. | ||
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10.1016/j.chroma.2015.11.056 doi GBVA2015022000005.pica (DE-627)ELV02933411X (ELSEVIER)S0021-9673(15)01684-2 DE-627 ger DE-627 rakwb eng 540 540 DE-600 300 600 VZ 50.14 bkl Barhate, Chandan L. verfasserin aut Ultrafast separation of fluorinated and desfluorinated pharmaceuticals using highly efficient and selective chiral selectors bonded to superficially porous particles 2015 7 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier • Ultrafast separations of fluorinated drugs from corresponding desfluoro impurities. • Macrocyclic chiral selectors bonded to superficially porous particles were tested. • The chiral phases showed enhanced selectivity compared to other achiral phases. • HPLC-ESI-MS compatibility was demonstrated. • All separations are carried out under isocratic conditions. Ultrafast separations Elsevier Superficially porous particles Elsevier Desfluorinated impurities Elsevier Dehalogenation impurities Elsevier UHPLC Elsevier Fluorine-containing drugs Elsevier Breitbach, Zachary S. oth Pinto, Eduardo Costa oth Regalado, Erik L. oth Welch, Christopher J. oth Armstrong, Daniel W. oth Enthalten in Science Direct Liwång, Hans ELSEVIER Defense development: The role of co-creation in filling the gap between policy-makers and technology development 2022 including electrophoresis, mass spectrometry and other separation and detection methods New York, NY [u.a.] (DE-627)ELV00750974X volume:1426 year:2015 day:24 month:12 pages:241-247 extent:7 https://doi.org/10.1016/j.chroma.2015.11.056 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U 50.14 Technik in Beziehung zu anderen Gebieten VZ AR 1426 2015 24 1224 241-247 7 045F 540 |
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10.1016/j.chroma.2015.11.056 doi GBVA2015022000005.pica (DE-627)ELV02933411X (ELSEVIER)S0021-9673(15)01684-2 DE-627 ger DE-627 rakwb eng 540 540 DE-600 300 600 VZ 50.14 bkl Barhate, Chandan L. verfasserin aut Ultrafast separation of fluorinated and desfluorinated pharmaceuticals using highly efficient and selective chiral selectors bonded to superficially porous particles 2015 7 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier • Ultrafast separations of fluorinated drugs from corresponding desfluoro impurities. • Macrocyclic chiral selectors bonded to superficially porous particles were tested. • The chiral phases showed enhanced selectivity compared to other achiral phases. • HPLC-ESI-MS compatibility was demonstrated. • All separations are carried out under isocratic conditions. Ultrafast separations Elsevier Superficially porous particles Elsevier Desfluorinated impurities Elsevier Dehalogenation impurities Elsevier UHPLC Elsevier Fluorine-containing drugs Elsevier Breitbach, Zachary S. oth Pinto, Eduardo Costa oth Regalado, Erik L. oth Welch, Christopher J. oth Armstrong, Daniel W. oth Enthalten in Science Direct Liwång, Hans ELSEVIER Defense development: The role of co-creation in filling the gap between policy-makers and technology development 2022 including electrophoresis, mass spectrometry and other separation and detection methods New York, NY [u.a.] (DE-627)ELV00750974X volume:1426 year:2015 day:24 month:12 pages:241-247 extent:7 https://doi.org/10.1016/j.chroma.2015.11.056 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U 50.14 Technik in Beziehung zu anderen Gebieten VZ AR 1426 2015 24 1224 241-247 7 045F 540 |
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ultrafast separation of fluorinated and desfluorinated pharmaceuticals using highly efficient and selective chiral selectors bonded to superficially porous particles |
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Ultrafast separation of fluorinated and desfluorinated pharmaceuticals using highly efficient and selective chiral selectors bonded to superficially porous particles |
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• Ultrafast separations of fluorinated drugs from corresponding desfluoro impurities. • Macrocyclic chiral selectors bonded to superficially porous particles were tested. • The chiral phases showed enhanced selectivity compared to other achiral phases. • HPLC-ESI-MS compatibility was demonstrated. • All separations are carried out under isocratic conditions. |
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• Ultrafast separations of fluorinated drugs from corresponding desfluoro impurities. • Macrocyclic chiral selectors bonded to superficially porous particles were tested. • The chiral phases showed enhanced selectivity compared to other achiral phases. • HPLC-ESI-MS compatibility was demonstrated. • All separations are carried out under isocratic conditions. |
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• Ultrafast separations of fluorinated drugs from corresponding desfluoro impurities. • Macrocyclic chiral selectors bonded to superficially porous particles were tested. • The chiral phases showed enhanced selectivity compared to other achiral phases. • HPLC-ESI-MS compatibility was demonstrated. • All separations are carried out under isocratic conditions. |
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Ultrafast separation of fluorinated and desfluorinated pharmaceuticals using highly efficient and selective chiral selectors bonded to superficially porous particles |
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https://doi.org/10.1016/j.chroma.2015.11.056 |
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Breitbach, Zachary S. Pinto, Eduardo Costa Regalado, Erik L. Welch, Christopher J. Armstrong, Daniel W. |
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Breitbach, Zachary S. Pinto, Eduardo Costa Regalado, Erik L. Welch, Christopher J. Armstrong, Daniel W. |
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| doi_str |
10.1016/j.chroma.2015.11.056 |
| up_date |
2024-07-06T21:11:11.561Z |
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