Role of chromatin structure modulation by the histone deacetylase inhibitor trichostatin A on the radio-sensitivity of ataxia telangiectasia
• Role of chromatin compaction on chromosomal instability. • Reduced radiation-induced clastogenicity in Ataxia telangiectasia cell lines. • Histone tails hyperacetylation reduces heterochromatin content favouring DSBs repair.
Gespeichert in:
| Autor*in: |
Meschini, Roberta [verfasserIn] |
|---|
| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2015 |
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| Schlagwörter: |
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| Umfang: |
8 |
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| Übergeordnetes Werk: |
Enthalten in: Hydrogen spillover storage on Ca-decorated graphene - 2012transfer abstract, an international journal on mutagenesis, chromosome breakage and related subjects, Amsterdam |
|---|---|
| Übergeordnetes Werk: |
volume:777 ; year:2015 ; pages:52-59 ; extent:8 |
| Links: |
|---|
| DOI / URN: |
10.1016/j.mrfmmm.2015.04.009 |
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Role of chromatin structure modulation by the histone deacetylase inhibitor trichostatin A on the radio-sensitivity of ataxia telangiectasia |
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• Role of chromatin compaction on chromosomal instability. • Reduced radiation-induced clastogenicity in Ataxia telangiectasia cell lines. • Histone tails hyperacetylation reduces heterochromatin content favouring DSBs repair. |
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