Suberoylanilide hydroxamic acid inhibits growth of head and neck cancer cell lines by reactivation of tumor suppressor microRNAs
• SAHA treatment results in reactivation of the silenced tumor suppressor miRs. • SAHA treatment reduced expression of PKCε, HIF1β, CDK6, and RhoC oncoproteins. • Combination treatment with SAHA and cisplatin reduced cell growth significantly. • SAHA treatment enhances the efficacy of standard chemo...
Ausführliche Beschreibung
Autor*in: |
Datta, Jharna [verfasserIn] |
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Format: |
E-Artikel |
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Sprache: |
Englisch |
Erschienen: |
2016 |
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Schlagwörter: |
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Umfang: |
8 |
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Übergeordnetes Werk: |
Enthalten in: Anti-anaerobic activity of a new β-lactamase inhibitor NXL104 in combination with β-lactams and metronidazole - 2012transfer abstract, Amsterdam [u.a.] |
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Übergeordnetes Werk: |
volume:56 ; year:2016 ; pages:32-39 ; extent:8 |
Links: |
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DOI / URN: |
10.1016/j.oraloncology.2016.02.015 |
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ELV029476305 |
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Suberoylanilide hydroxamic acid inhibits growth of head and neck cancer cell lines by reactivation of tumor suppressor microRNAs |
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(DE-627)ELV029476305 (ELSEVIER)S1368-8375(16)00045-2 |
title_full |
Suberoylanilide hydroxamic acid inhibits growth of head and neck cancer cell lines by reactivation of tumor suppressor microRNAs |
author_sort |
Datta, Jharna |
journal |
Anti-anaerobic activity of a new β-lactamase inhibitor NXL104 in combination with β-lactams and metronidazole |
journalStr |
Anti-anaerobic activity of a new β-lactamase inhibitor NXL104 in combination with β-lactams and metronidazole |
lang_code |
eng |
isOA_bool |
false |
dewey-hundreds |
600 - Technology |
recordtype |
marc |
publishDateSort |
2016 |
contenttype_str_mv |
zzz |
container_start_page |
32 |
author_browse |
Datta, Jharna |
container_volume |
56 |
physical |
8 |
class |
610 610 DE-600 610 VZ 650 VZ 85.03 bkl 31.80 bkl 54.80 bkl 50.03 bkl |
format_se |
Elektronische Aufsätze |
author-letter |
Datta, Jharna |
doi_str_mv |
10.1016/j.oraloncology.2016.02.015 |
dewey-full |
610 650 |
title_sort |
suberoylanilide hydroxamic acid inhibits growth of head and neck cancer cell lines by reactivation of tumor suppressor micrornas |
title_auth |
Suberoylanilide hydroxamic acid inhibits growth of head and neck cancer cell lines by reactivation of tumor suppressor microRNAs |
abstract |
• SAHA treatment results in reactivation of the silenced tumor suppressor miRs. • SAHA treatment reduced expression of PKCε, HIF1β, CDK6, and RhoC oncoproteins. • Combination treatment with SAHA and cisplatin reduced cell growth significantly. • SAHA treatment enhances the efficacy of standard chemo-/radiation therapy in HNSCC. |
abstractGer |
• SAHA treatment results in reactivation of the silenced tumor suppressor miRs. • SAHA treatment reduced expression of PKCε, HIF1β, CDK6, and RhoC oncoproteins. • Combination treatment with SAHA and cisplatin reduced cell growth significantly. • SAHA treatment enhances the efficacy of standard chemo-/radiation therapy in HNSCC. |
abstract_unstemmed |
• SAHA treatment results in reactivation of the silenced tumor suppressor miRs. • SAHA treatment reduced expression of PKCε, HIF1β, CDK6, and RhoC oncoproteins. • Combination treatment with SAHA and cisplatin reduced cell growth significantly. • SAHA treatment enhances the efficacy of standard chemo-/radiation therapy in HNSCC. |
collection_details |
GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OPC-MAT |
title_short |
Suberoylanilide hydroxamic acid inhibits growth of head and neck cancer cell lines by reactivation of tumor suppressor microRNAs |
url |
https://doi.org/10.1016/j.oraloncology.2016.02.015 |
remote_bool |
true |
author2 |
Islam, Mozaffarul Dutta, Samidha Roy, Sounak Pan, Quintin Teknos, Theodoros N. |
author2Str |
Islam, Mozaffarul Dutta, Samidha Roy, Sounak Pan, Quintin Teknos, Theodoros N. |
ppnlink |
ELV011194073 |
mediatype_str_mv |
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author2_role |
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doi_str |
10.1016/j.oraloncology.2016.02.015 |
up_date |
2024-07-06T21:34:02.293Z |
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1803867014871121920 |
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