Nicotine enhances the malignant potential of human pancreatic cancer cells via activation of atypical protein kinase C
Pancreatic cancer (PC) is the most lethal malignancy among solid tumors, and the most common risk factor for its development is cigarette smoking. Atypical protein kinase C (aPKC) isozymes function in cell polarity, proliferation, and survival, and have also been implicated in carcinogenesis. Howeve...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Hanaki, Takehiko [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2016 |
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| Umfang: |
12 |
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Enthalten in: Numerical simulation of the effect of cement particle shapes on capillary pore structures in hardened cement pastes - Liu, Cheng ELSEVIER, 2018, BBA, Amsterdam [u.a.] |
|---|---|
| Übergeordnetes Werk: |
volume:1860 ; year:2016 ; number:11 ; pages:2404-2415 ; extent:12 |
| Links: |
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| DOI / URN: |
10.1016/j.bbagen.2016.07.008 |
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| 520 | |a Pancreatic cancer (PC) is the most lethal malignancy among solid tumors, and the most common risk factor for its development is cigarette smoking. Atypical protein kinase C (aPKC) isozymes function in cell polarity, proliferation, and survival, and have also been implicated in carcinogenesis. However, the involvement of aPKC in PC progression and the effect of nicotine, a major component of cigarette smoke, on the biological activities of aPKC remain to be fully elucidated. | ||
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10.1016/j.bbagen.2016.07.008 doi GBVA2016010000022.pica (DE-627)ELV029696895 (ELSEVIER)S0304-4165(16)30249-5 DE-627 ger DE-627 rakwb eng 570 610 570 DE-600 610 DE-600 690 VZ 56.45 bkl Hanaki, Takehiko verfasserin aut Nicotine enhances the malignant potential of human pancreatic cancer cells via activation of atypical protein kinase C 2016 12 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Pancreatic cancer (PC) is the most lethal malignancy among solid tumors, and the most common risk factor for its development is cigarette smoking. Atypical protein kinase C (aPKC) isozymes function in cell polarity, proliferation, and survival, and have also been implicated in carcinogenesis. However, the involvement of aPKC in PC progression and the effect of nicotine, a major component of cigarette smoke, on the biological activities of aPKC remain to be fully elucidated. Horikoshi, Yosuke oth Nakaso, Kazuhiro oth Nakasone, Masato oth Kitagawa, Yoshinori oth Amisaki, Masataka oth Arai, Yosuke oth Tokuyasu, Naruo oth Sakamoto, Teruhisa oth Honjo, Soichiro oth Saito, Hiroaki oth Ikeguchi, Masahide oth Yamashita, Kazunari oth Ohno, Shigeo oth Matsura, Tatsuya oth Enthalten in Elsevier Liu, Cheng ELSEVIER Numerical simulation of the effect of cement particle shapes on capillary pore structures in hardened cement pastes 2018 BBA Amsterdam [u.a.] (DE-627)ELV001681907 volume:1860 year:2016 number:11 pages:2404-2415 extent:12 https://doi.org/10.1016/j.bbagen.2016.07.008 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U 56.45 Baustoffkunde VZ AR 1860 2016 11 2404-2415 12 045F 570 |
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Nicotine enhances the malignant potential of human pancreatic cancer cells via activation of atypical protein kinase C |
| abstract |
Pancreatic cancer (PC) is the most lethal malignancy among solid tumors, and the most common risk factor for its development is cigarette smoking. Atypical protein kinase C (aPKC) isozymes function in cell polarity, proliferation, and survival, and have also been implicated in carcinogenesis. However, the involvement of aPKC in PC progression and the effect of nicotine, a major component of cigarette smoke, on the biological activities of aPKC remain to be fully elucidated. |
| abstractGer |
Pancreatic cancer (PC) is the most lethal malignancy among solid tumors, and the most common risk factor for its development is cigarette smoking. Atypical protein kinase C (aPKC) isozymes function in cell polarity, proliferation, and survival, and have also been implicated in carcinogenesis. However, the involvement of aPKC in PC progression and the effect of nicotine, a major component of cigarette smoke, on the biological activities of aPKC remain to be fully elucidated. |
| abstract_unstemmed |
Pancreatic cancer (PC) is the most lethal malignancy among solid tumors, and the most common risk factor for its development is cigarette smoking. Atypical protein kinase C (aPKC) isozymes function in cell polarity, proliferation, and survival, and have also been implicated in carcinogenesis. However, the involvement of aPKC in PC progression and the effect of nicotine, a major component of cigarette smoke, on the biological activities of aPKC remain to be fully elucidated. |
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| title_short |
Nicotine enhances the malignant potential of human pancreatic cancer cells via activation of atypical protein kinase C |
| url |
https://doi.org/10.1016/j.bbagen.2016.07.008 |
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| author2 |
Horikoshi, Yosuke Nakaso, Kazuhiro Nakasone, Masato Kitagawa, Yoshinori Amisaki, Masataka Arai, Yosuke Tokuyasu, Naruo Sakamoto, Teruhisa Honjo, Soichiro Saito, Hiroaki Ikeguchi, Masahide Yamashita, Kazunari Ohno, Shigeo Matsura, Tatsuya |
| author2Str |
Horikoshi, Yosuke Nakaso, Kazuhiro Nakasone, Masato Kitagawa, Yoshinori Amisaki, Masataka Arai, Yosuke Tokuyasu, Naruo Sakamoto, Teruhisa Honjo, Soichiro Saito, Hiroaki Ikeguchi, Masahide Yamashita, Kazunari Ohno, Shigeo Matsura, Tatsuya |
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| doi_str |
10.1016/j.bbagen.2016.07.008 |
| up_date |
2024-07-06T22:07:48.942Z |
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