Evaluation of MALDI-TOF MS (Matrix-Assisted Laser Desorption-Ionization Time-of-Flight Mass Spectrometry) for routine identification of anaerobic bacteria
Information regarding the use of MALDI-TOF MS as an alternative to conventional laboratory methods for the rapid and reliable identification of bacterial isolates is still limited. In this study, MALDI-TOF MS was evaluated on 295 anaerobic isolates previously identified by 16S rRNA gene sequencing a...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Rodríguez-Sánchez, Belén [verfasserIn] |
|---|
| Format: |
E-Artikel |
|---|---|
| Sprache: |
Englisch |
| Erschienen: |
2016transfer abstract |
|---|
| Schlagwörter: |
|---|
| Umfang: |
7 |
|---|
| Übergeordnetes Werk: |
Enthalten in: Design, synthesis and biological evaluation of 5-amino-4-(1H-benzoimidazol-2-yl)-phenyl-1,2-dihydro-pyrrol-3-ones as inhibitors of protein kinase FGFR1 - Gryshchenko, A.A. ELSEVIER, 2016, the official journal of the Anaerobe Society of the Americas, London |
|---|---|
| Übergeordnetes Werk: |
volume:42 ; year:2016 ; pages:101-107 ; extent:7 |
| Links: |
|---|
| DOI / URN: |
10.1016/j.anaerobe.2016.09.009 |
|---|
| Katalog-ID: |
ELV029968720 |
|---|
| LEADER | 01000caa a22002652 4500 | ||
|---|---|---|---|
| 001 | ELV029968720 | ||
| 003 | DE-627 | ||
| 005 | 20230625180052.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 180603s2016 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1016/j.anaerobe.2016.09.009 |2 doi | |
| 028 | 5 | 2 | |a GBV00000000000087A.pica |
| 035 | |a (DE-627)ELV029968720 | ||
| 035 | |a (ELSEVIER)S1075-9964(16)30118-4 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 082 | 0 | |a 570 |a 610 | |
| 082 | 0 | 4 | |a 570 |q DE-600 |
| 082 | 0 | 4 | |a 610 |q DE-600 |
| 082 | 0 | 4 | |a 540 |q VZ |
| 082 | 0 | 4 | |a 610 |q VZ |
| 082 | 0 | 4 | |a 004 |q VZ |
| 084 | |a 53.70 |2 bkl | ||
| 084 | |a 05.42 |2 bkl | ||
| 084 | |a 53.76 |2 bkl | ||
| 084 | |a 54.00 |2 bkl | ||
| 100 | 1 | |a Rodríguez-Sánchez, Belén |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Evaluation of MALDI-TOF MS (Matrix-Assisted Laser Desorption-Ionization Time-of-Flight Mass Spectrometry) for routine identification of anaerobic bacteria |
| 264 | 1 | |c 2016transfer abstract | |
| 300 | |a 7 | ||
| 336 | |a nicht spezifiziert |b zzz |2 rdacontent | ||
| 337 | |a nicht spezifiziert |b z |2 rdamedia | ||
| 338 | |a nicht spezifiziert |b zu |2 rdacarrier | ||
| 520 | |a Information regarding the use of MALDI-TOF MS as an alternative to conventional laboratory methods for the rapid and reliable identification of bacterial isolates is still limited. In this study, MALDI-TOF MS was evaluated on 295 anaerobic isolates previously identified by 16S rRNA gene sequencing and with biochemical tests (Rapid ID 32A system, BioMérieux). In total, 85.8% of the isolates were identified by MALDI-TOF MS at the species level vs 49.8% using the Rapid ID 32A system (p < 0.0001). None of the isolates was discordantly identified at the genus level using MALDI-TOF MS and only 9 of them could not be identified using the method. Thus, our results show that MALDI-TOF MS is a robust and reliable tool for the identification of anaerobic isolates in the microbiology laboratory. Its implementation will reduce the turnaround time for a final identification and the number of isolates that require 16S rRNA sequencing. | ||
| 520 | |a Information regarding the use of MALDI-TOF MS as an alternative to conventional laboratory methods for the rapid and reliable identification of bacterial isolates is still limited. In this study, MALDI-TOF MS was evaluated on 295 anaerobic isolates previously identified by 16S rRNA gene sequencing and with biochemical tests (Rapid ID 32A system, BioMérieux). In total, 85.8% of the isolates were identified by MALDI-TOF MS at the species level vs 49.8% using the Rapid ID 32A system (p < 0.0001). None of the isolates was discordantly identified at the genus level using MALDI-TOF MS and only 9 of them could not be identified using the method. Thus, our results show that MALDI-TOF MS is a robust and reliable tool for the identification of anaerobic isolates in the microbiology laboratory. Its implementation will reduce the turnaround time for a final identification and the number of isolates that require 16S rRNA sequencing. | ||
| 650 | 7 | |a MALDI-TOF MS |2 Elsevier | |
| 650 | 7 | |a Routine identification |2 Elsevier | |
| 650 | 7 | |a Anaerobic isolates |2 Elsevier | |
| 700 | 1 | |a Alcalá, Luis |4 oth | |
| 700 | 1 | |a Marín, Mercedes |4 oth | |
| 700 | 1 | |a Ruiz, Adrián |4 oth | |
| 700 | 1 | |a Alonso, Elena |4 oth | |
| 700 | 1 | |a Bouza, Emilio |4 oth | |
| 773 | 0 | 8 | |i Enthalten in |n Academic Press |a Gryshchenko, A.A. ELSEVIER |t Design, synthesis and biological evaluation of 5-amino-4-(1H-benzoimidazol-2-yl)-phenyl-1,2-dihydro-pyrrol-3-ones as inhibitors of protein kinase FGFR1 |d 2016 |d the official journal of the Anaerobe Society of the Americas |g London |w (DE-627)ELV019616112 |
| 773 | 1 | 8 | |g volume:42 |g year:2016 |g pages:101-107 |g extent:7 |
| 856 | 4 | 0 | |u https://doi.org/10.1016/j.anaerobe.2016.09.009 |3 Volltext |
| 912 | |a GBV_USEFLAG_U | ||
| 912 | |a GBV_ELV | ||
| 912 | |a SYSFLAG_U | ||
| 912 | |a GBV_ILN_70 | ||
| 936 | b | k | |a 53.70 |j Nachrichtentechnik |j Kommunikationstechnik: Allgemeines |q VZ |
| 936 | b | k | |a 05.42 |j Telekommunikation |q VZ |
| 936 | b | k | |a 53.76 |j Kommunikationsdienste |j Fernmeldetechnik |q VZ |
| 936 | b | k | |a 54.00 |j Informatik: Allgemeines |q VZ |
| 951 | |a AR | ||
| 952 | |d 42 |j 2016 |h 101-107 |g 7 | ||
| 953 | |2 045F |a 570 | ||
| author_variant |
b r s brs |
|---|---|
| matchkey_str |
rodrguezsnchezbelnalcalluismarnmercedesr:2016----:vlainfadtfsarxsitdaedsrtoinztotmofihmssetoerfrotn |
| hierarchy_sort_str |
2016transfer abstract |
| bklnumber |
53.70 05.42 53.76 54.00 |
| publishDate |
2016 |
| allfields |
10.1016/j.anaerobe.2016.09.009 doi GBV00000000000087A.pica (DE-627)ELV029968720 (ELSEVIER)S1075-9964(16)30118-4 DE-627 ger DE-627 rakwb eng 570 610 570 DE-600 610 DE-600 540 VZ 610 VZ 004 VZ 53.70 bkl 05.42 bkl 53.76 bkl 54.00 bkl Rodríguez-Sánchez, Belén verfasserin aut Evaluation of MALDI-TOF MS (Matrix-Assisted Laser Desorption-Ionization Time-of-Flight Mass Spectrometry) for routine identification of anaerobic bacteria 2016transfer abstract 7 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Information regarding the use of MALDI-TOF MS as an alternative to conventional laboratory methods for the rapid and reliable identification of bacterial isolates is still limited. In this study, MALDI-TOF MS was evaluated on 295 anaerobic isolates previously identified by 16S rRNA gene sequencing and with biochemical tests (Rapid ID 32A system, BioMérieux). In total, 85.8% of the isolates were identified by MALDI-TOF MS at the species level vs 49.8% using the Rapid ID 32A system (p < 0.0001). None of the isolates was discordantly identified at the genus level using MALDI-TOF MS and only 9 of them could not be identified using the method. Thus, our results show that MALDI-TOF MS is a robust and reliable tool for the identification of anaerobic isolates in the microbiology laboratory. Its implementation will reduce the turnaround time for a final identification and the number of isolates that require 16S rRNA sequencing. Information regarding the use of MALDI-TOF MS as an alternative to conventional laboratory methods for the rapid and reliable identification of bacterial isolates is still limited. In this study, MALDI-TOF MS was evaluated on 295 anaerobic isolates previously identified by 16S rRNA gene sequencing and with biochemical tests (Rapid ID 32A system, BioMérieux). In total, 85.8% of the isolates were identified by MALDI-TOF MS at the species level vs 49.8% using the Rapid ID 32A system (p < 0.0001). None of the isolates was discordantly identified at the genus level using MALDI-TOF MS and only 9 of them could not be identified using the method. Thus, our results show that MALDI-TOF MS is a robust and reliable tool for the identification of anaerobic isolates in the microbiology laboratory. Its implementation will reduce the turnaround time for a final identification and the number of isolates that require 16S rRNA sequencing. MALDI-TOF MS Elsevier Routine identification Elsevier Anaerobic isolates Elsevier Alcalá, Luis oth Marín, Mercedes oth Ruiz, Adrián oth Alonso, Elena oth Bouza, Emilio oth Enthalten in Academic Press Gryshchenko, A.A. ELSEVIER Design, synthesis and biological evaluation of 5-amino-4-(1H-benzoimidazol-2-yl)-phenyl-1,2-dihydro-pyrrol-3-ones as inhibitors of protein kinase FGFR1 2016 the official journal of the Anaerobe Society of the Americas London (DE-627)ELV019616112 volume:42 year:2016 pages:101-107 extent:7 https://doi.org/10.1016/j.anaerobe.2016.09.009 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U GBV_ILN_70 53.70 Nachrichtentechnik Kommunikationstechnik: Allgemeines VZ 05.42 Telekommunikation VZ 53.76 Kommunikationsdienste Fernmeldetechnik VZ 54.00 Informatik: Allgemeines VZ AR 42 2016 101-107 7 045F 570 |
| spelling |
10.1016/j.anaerobe.2016.09.009 doi GBV00000000000087A.pica (DE-627)ELV029968720 (ELSEVIER)S1075-9964(16)30118-4 DE-627 ger DE-627 rakwb eng 570 610 570 DE-600 610 DE-600 540 VZ 610 VZ 004 VZ 53.70 bkl 05.42 bkl 53.76 bkl 54.00 bkl Rodríguez-Sánchez, Belén verfasserin aut Evaluation of MALDI-TOF MS (Matrix-Assisted Laser Desorption-Ionization Time-of-Flight Mass Spectrometry) for routine identification of anaerobic bacteria 2016transfer abstract 7 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Information regarding the use of MALDI-TOF MS as an alternative to conventional laboratory methods for the rapid and reliable identification of bacterial isolates is still limited. In this study, MALDI-TOF MS was evaluated on 295 anaerobic isolates previously identified by 16S rRNA gene sequencing and with biochemical tests (Rapid ID 32A system, BioMérieux). In total, 85.8% of the isolates were identified by MALDI-TOF MS at the species level vs 49.8% using the Rapid ID 32A system (p < 0.0001). None of the isolates was discordantly identified at the genus level using MALDI-TOF MS and only 9 of them could not be identified using the method. Thus, our results show that MALDI-TOF MS is a robust and reliable tool for the identification of anaerobic isolates in the microbiology laboratory. Its implementation will reduce the turnaround time for a final identification and the number of isolates that require 16S rRNA sequencing. Information regarding the use of MALDI-TOF MS as an alternative to conventional laboratory methods for the rapid and reliable identification of bacterial isolates is still limited. In this study, MALDI-TOF MS was evaluated on 295 anaerobic isolates previously identified by 16S rRNA gene sequencing and with biochemical tests (Rapid ID 32A system, BioMérieux). In total, 85.8% of the isolates were identified by MALDI-TOF MS at the species level vs 49.8% using the Rapid ID 32A system (p < 0.0001). None of the isolates was discordantly identified at the genus level using MALDI-TOF MS and only 9 of them could not be identified using the method. Thus, our results show that MALDI-TOF MS is a robust and reliable tool for the identification of anaerobic isolates in the microbiology laboratory. Its implementation will reduce the turnaround time for a final identification and the number of isolates that require 16S rRNA sequencing. MALDI-TOF MS Elsevier Routine identification Elsevier Anaerobic isolates Elsevier Alcalá, Luis oth Marín, Mercedes oth Ruiz, Adrián oth Alonso, Elena oth Bouza, Emilio oth Enthalten in Academic Press Gryshchenko, A.A. ELSEVIER Design, synthesis and biological evaluation of 5-amino-4-(1H-benzoimidazol-2-yl)-phenyl-1,2-dihydro-pyrrol-3-ones as inhibitors of protein kinase FGFR1 2016 the official journal of the Anaerobe Society of the Americas London (DE-627)ELV019616112 volume:42 year:2016 pages:101-107 extent:7 https://doi.org/10.1016/j.anaerobe.2016.09.009 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U GBV_ILN_70 53.70 Nachrichtentechnik Kommunikationstechnik: Allgemeines VZ 05.42 Telekommunikation VZ 53.76 Kommunikationsdienste Fernmeldetechnik VZ 54.00 Informatik: Allgemeines VZ AR 42 2016 101-107 7 045F 570 |
| allfields_unstemmed |
10.1016/j.anaerobe.2016.09.009 doi GBV00000000000087A.pica (DE-627)ELV029968720 (ELSEVIER)S1075-9964(16)30118-4 DE-627 ger DE-627 rakwb eng 570 610 570 DE-600 610 DE-600 540 VZ 610 VZ 004 VZ 53.70 bkl 05.42 bkl 53.76 bkl 54.00 bkl Rodríguez-Sánchez, Belén verfasserin aut Evaluation of MALDI-TOF MS (Matrix-Assisted Laser Desorption-Ionization Time-of-Flight Mass Spectrometry) for routine identification of anaerobic bacteria 2016transfer abstract 7 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Information regarding the use of MALDI-TOF MS as an alternative to conventional laboratory methods for the rapid and reliable identification of bacterial isolates is still limited. In this study, MALDI-TOF MS was evaluated on 295 anaerobic isolates previously identified by 16S rRNA gene sequencing and with biochemical tests (Rapid ID 32A system, BioMérieux). In total, 85.8% of the isolates were identified by MALDI-TOF MS at the species level vs 49.8% using the Rapid ID 32A system (p < 0.0001). None of the isolates was discordantly identified at the genus level using MALDI-TOF MS and only 9 of them could not be identified using the method. Thus, our results show that MALDI-TOF MS is a robust and reliable tool for the identification of anaerobic isolates in the microbiology laboratory. Its implementation will reduce the turnaround time for a final identification and the number of isolates that require 16S rRNA sequencing. Information regarding the use of MALDI-TOF MS as an alternative to conventional laboratory methods for the rapid and reliable identification of bacterial isolates is still limited. In this study, MALDI-TOF MS was evaluated on 295 anaerobic isolates previously identified by 16S rRNA gene sequencing and with biochemical tests (Rapid ID 32A system, BioMérieux). In total, 85.8% of the isolates were identified by MALDI-TOF MS at the species level vs 49.8% using the Rapid ID 32A system (p < 0.0001). None of the isolates was discordantly identified at the genus level using MALDI-TOF MS and only 9 of them could not be identified using the method. Thus, our results show that MALDI-TOF MS is a robust and reliable tool for the identification of anaerobic isolates in the microbiology laboratory. Its implementation will reduce the turnaround time for a final identification and the number of isolates that require 16S rRNA sequencing. MALDI-TOF MS Elsevier Routine identification Elsevier Anaerobic isolates Elsevier Alcalá, Luis oth Marín, Mercedes oth Ruiz, Adrián oth Alonso, Elena oth Bouza, Emilio oth Enthalten in Academic Press Gryshchenko, A.A. ELSEVIER Design, synthesis and biological evaluation of 5-amino-4-(1H-benzoimidazol-2-yl)-phenyl-1,2-dihydro-pyrrol-3-ones as inhibitors of protein kinase FGFR1 2016 the official journal of the Anaerobe Society of the Americas London (DE-627)ELV019616112 volume:42 year:2016 pages:101-107 extent:7 https://doi.org/10.1016/j.anaerobe.2016.09.009 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U GBV_ILN_70 53.70 Nachrichtentechnik Kommunikationstechnik: Allgemeines VZ 05.42 Telekommunikation VZ 53.76 Kommunikationsdienste Fernmeldetechnik VZ 54.00 Informatik: Allgemeines VZ AR 42 2016 101-107 7 045F 570 |
| allfieldsGer |
10.1016/j.anaerobe.2016.09.009 doi GBV00000000000087A.pica (DE-627)ELV029968720 (ELSEVIER)S1075-9964(16)30118-4 DE-627 ger DE-627 rakwb eng 570 610 570 DE-600 610 DE-600 540 VZ 610 VZ 004 VZ 53.70 bkl 05.42 bkl 53.76 bkl 54.00 bkl Rodríguez-Sánchez, Belén verfasserin aut Evaluation of MALDI-TOF MS (Matrix-Assisted Laser Desorption-Ionization Time-of-Flight Mass Spectrometry) for routine identification of anaerobic bacteria 2016transfer abstract 7 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Information regarding the use of MALDI-TOF MS as an alternative to conventional laboratory methods for the rapid and reliable identification of bacterial isolates is still limited. In this study, MALDI-TOF MS was evaluated on 295 anaerobic isolates previously identified by 16S rRNA gene sequencing and with biochemical tests (Rapid ID 32A system, BioMérieux). In total, 85.8% of the isolates were identified by MALDI-TOF MS at the species level vs 49.8% using the Rapid ID 32A system (p < 0.0001). None of the isolates was discordantly identified at the genus level using MALDI-TOF MS and only 9 of them could not be identified using the method. Thus, our results show that MALDI-TOF MS is a robust and reliable tool for the identification of anaerobic isolates in the microbiology laboratory. Its implementation will reduce the turnaround time for a final identification and the number of isolates that require 16S rRNA sequencing. Information regarding the use of MALDI-TOF MS as an alternative to conventional laboratory methods for the rapid and reliable identification of bacterial isolates is still limited. In this study, MALDI-TOF MS was evaluated on 295 anaerobic isolates previously identified by 16S rRNA gene sequencing and with biochemical tests (Rapid ID 32A system, BioMérieux). In total, 85.8% of the isolates were identified by MALDI-TOF MS at the species level vs 49.8% using the Rapid ID 32A system (p < 0.0001). None of the isolates was discordantly identified at the genus level using MALDI-TOF MS and only 9 of them could not be identified using the method. Thus, our results show that MALDI-TOF MS is a robust and reliable tool for the identification of anaerobic isolates in the microbiology laboratory. Its implementation will reduce the turnaround time for a final identification and the number of isolates that require 16S rRNA sequencing. MALDI-TOF MS Elsevier Routine identification Elsevier Anaerobic isolates Elsevier Alcalá, Luis oth Marín, Mercedes oth Ruiz, Adrián oth Alonso, Elena oth Bouza, Emilio oth Enthalten in Academic Press Gryshchenko, A.A. ELSEVIER Design, synthesis and biological evaluation of 5-amino-4-(1H-benzoimidazol-2-yl)-phenyl-1,2-dihydro-pyrrol-3-ones as inhibitors of protein kinase FGFR1 2016 the official journal of the Anaerobe Society of the Americas London (DE-627)ELV019616112 volume:42 year:2016 pages:101-107 extent:7 https://doi.org/10.1016/j.anaerobe.2016.09.009 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U GBV_ILN_70 53.70 Nachrichtentechnik Kommunikationstechnik: Allgemeines VZ 05.42 Telekommunikation VZ 53.76 Kommunikationsdienste Fernmeldetechnik VZ 54.00 Informatik: Allgemeines VZ AR 42 2016 101-107 7 045F 570 |
| allfieldsSound |
10.1016/j.anaerobe.2016.09.009 doi GBV00000000000087A.pica (DE-627)ELV029968720 (ELSEVIER)S1075-9964(16)30118-4 DE-627 ger DE-627 rakwb eng 570 610 570 DE-600 610 DE-600 540 VZ 610 VZ 004 VZ 53.70 bkl 05.42 bkl 53.76 bkl 54.00 bkl Rodríguez-Sánchez, Belén verfasserin aut Evaluation of MALDI-TOF MS (Matrix-Assisted Laser Desorption-Ionization Time-of-Flight Mass Spectrometry) for routine identification of anaerobic bacteria 2016transfer abstract 7 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Information regarding the use of MALDI-TOF MS as an alternative to conventional laboratory methods for the rapid and reliable identification of bacterial isolates is still limited. In this study, MALDI-TOF MS was evaluated on 295 anaerobic isolates previously identified by 16S rRNA gene sequencing and with biochemical tests (Rapid ID 32A system, BioMérieux). In total, 85.8% of the isolates were identified by MALDI-TOF MS at the species level vs 49.8% using the Rapid ID 32A system (p < 0.0001). None of the isolates was discordantly identified at the genus level using MALDI-TOF MS and only 9 of them could not be identified using the method. Thus, our results show that MALDI-TOF MS is a robust and reliable tool for the identification of anaerobic isolates in the microbiology laboratory. Its implementation will reduce the turnaround time for a final identification and the number of isolates that require 16S rRNA sequencing. Information regarding the use of MALDI-TOF MS as an alternative to conventional laboratory methods for the rapid and reliable identification of bacterial isolates is still limited. In this study, MALDI-TOF MS was evaluated on 295 anaerobic isolates previously identified by 16S rRNA gene sequencing and with biochemical tests (Rapid ID 32A system, BioMérieux). In total, 85.8% of the isolates were identified by MALDI-TOF MS at the species level vs 49.8% using the Rapid ID 32A system (p < 0.0001). None of the isolates was discordantly identified at the genus level using MALDI-TOF MS and only 9 of them could not be identified using the method. Thus, our results show that MALDI-TOF MS is a robust and reliable tool for the identification of anaerobic isolates in the microbiology laboratory. Its implementation will reduce the turnaround time for a final identification and the number of isolates that require 16S rRNA sequencing. MALDI-TOF MS Elsevier Routine identification Elsevier Anaerobic isolates Elsevier Alcalá, Luis oth Marín, Mercedes oth Ruiz, Adrián oth Alonso, Elena oth Bouza, Emilio oth Enthalten in Academic Press Gryshchenko, A.A. ELSEVIER Design, synthesis and biological evaluation of 5-amino-4-(1H-benzoimidazol-2-yl)-phenyl-1,2-dihydro-pyrrol-3-ones as inhibitors of protein kinase FGFR1 2016 the official journal of the Anaerobe Society of the Americas London (DE-627)ELV019616112 volume:42 year:2016 pages:101-107 extent:7 https://doi.org/10.1016/j.anaerobe.2016.09.009 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U GBV_ILN_70 53.70 Nachrichtentechnik Kommunikationstechnik: Allgemeines VZ 05.42 Telekommunikation VZ 53.76 Kommunikationsdienste Fernmeldetechnik VZ 54.00 Informatik: Allgemeines VZ AR 42 2016 101-107 7 045F 570 |
| language |
English |
| source |
Enthalten in Design, synthesis and biological evaluation of 5-amino-4-(1H-benzoimidazol-2-yl)-phenyl-1,2-dihydro-pyrrol-3-ones as inhibitors of protein kinase FGFR1 London volume:42 year:2016 pages:101-107 extent:7 |
| sourceStr |
Enthalten in Design, synthesis and biological evaluation of 5-amino-4-(1H-benzoimidazol-2-yl)-phenyl-1,2-dihydro-pyrrol-3-ones as inhibitors of protein kinase FGFR1 London volume:42 year:2016 pages:101-107 extent:7 |
| format_phy_str_mv |
Article |
| bklname |
Nachrichtentechnik Kommunikationstechnik: Allgemeines Telekommunikation Kommunikationsdienste Fernmeldetechnik Informatik: Allgemeines |
| institution |
findex.gbv.de |
| topic_facet |
MALDI-TOF MS Routine identification Anaerobic isolates |
| dewey-raw |
570 |
| isfreeaccess_bool |
false |
| container_title |
Design, synthesis and biological evaluation of 5-amino-4-(1H-benzoimidazol-2-yl)-phenyl-1,2-dihydro-pyrrol-3-ones as inhibitors of protein kinase FGFR1 |
| authorswithroles_txt_mv |
Rodríguez-Sánchez, Belén @@aut@@ Alcalá, Luis @@oth@@ Marín, Mercedes @@oth@@ Ruiz, Adrián @@oth@@ Alonso, Elena @@oth@@ Bouza, Emilio @@oth@@ |
| publishDateDaySort_date |
2016-01-01T00:00:00Z |
| hierarchy_top_id |
ELV019616112 |
| dewey-sort |
3570 |
| id |
ELV029968720 |
| language_de |
englisch |
| fullrecord |
<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">ELV029968720</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230625180052.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">180603s2016 xx |||||o 00| ||eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1016/j.anaerobe.2016.09.009</subfield><subfield code="2">doi</subfield></datafield><datafield tag="028" ind1="5" ind2="2"><subfield code="a">GBV00000000000087A.pica</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)ELV029968720</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(ELSEVIER)S1075-9964(16)30118-4</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="082" ind1="0" ind2=" "><subfield code="a">570</subfield><subfield code="a">610</subfield></datafield><datafield tag="082" ind1="0" ind2="4"><subfield code="a">570</subfield><subfield code="q">DE-600</subfield></datafield><datafield tag="082" ind1="0" ind2="4"><subfield code="a">610</subfield><subfield code="q">DE-600</subfield></datafield><datafield tag="082" ind1="0" ind2="4"><subfield code="a">540</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="082" ind1="0" ind2="4"><subfield code="a">610</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="082" ind1="0" ind2="4"><subfield code="a">004</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">53.70</subfield><subfield code="2">bkl</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">05.42</subfield><subfield code="2">bkl</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">53.76</subfield><subfield code="2">bkl</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">54.00</subfield><subfield code="2">bkl</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Rodríguez-Sánchez, Belén</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Evaluation of MALDI-TOF MS (Matrix-Assisted Laser Desorption-Ionization Time-of-Flight Mass Spectrometry) for routine identification of anaerobic bacteria</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2016transfer abstract</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">7</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zzz</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">z</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zu</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Information regarding the use of MALDI-TOF MS as an alternative to conventional laboratory methods for the rapid and reliable identification of bacterial isolates is still limited. In this study, MALDI-TOF MS was evaluated on 295 anaerobic isolates previously identified by 16S rRNA gene sequencing and with biochemical tests (Rapid ID 32A system, BioMérieux). In total, 85.8% of the isolates were identified by MALDI-TOF MS at the species level vs 49.8% using the Rapid ID 32A system (p < 0.0001). None of the isolates was discordantly identified at the genus level using MALDI-TOF MS and only 9 of them could not be identified using the method. Thus, our results show that MALDI-TOF MS is a robust and reliable tool for the identification of anaerobic isolates in the microbiology laboratory. Its implementation will reduce the turnaround time for a final identification and the number of isolates that require 16S rRNA sequencing.</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Information regarding the use of MALDI-TOF MS as an alternative to conventional laboratory methods for the rapid and reliable identification of bacterial isolates is still limited. In this study, MALDI-TOF MS was evaluated on 295 anaerobic isolates previously identified by 16S rRNA gene sequencing and with biochemical tests (Rapid ID 32A system, BioMérieux). In total, 85.8% of the isolates were identified by MALDI-TOF MS at the species level vs 49.8% using the Rapid ID 32A system (p < 0.0001). None of the isolates was discordantly identified at the genus level using MALDI-TOF MS and only 9 of them could not be identified using the method. Thus, our results show that MALDI-TOF MS is a robust and reliable tool for the identification of anaerobic isolates in the microbiology laboratory. Its implementation will reduce the turnaround time for a final identification and the number of isolates that require 16S rRNA sequencing.</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">MALDI-TOF MS</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Routine identification</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Anaerobic isolates</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Alcalá, Luis</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Marín, Mercedes</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Ruiz, Adrián</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Alonso, Elena</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Bouza, Emilio</subfield><subfield code="4">oth</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">Enthalten in</subfield><subfield code="n">Academic Press</subfield><subfield code="a">Gryshchenko, A.A. ELSEVIER</subfield><subfield code="t">Design, synthesis and biological evaluation of 5-amino-4-(1H-benzoimidazol-2-yl)-phenyl-1,2-dihydro-pyrrol-3-ones as inhibitors of protein kinase FGFR1</subfield><subfield code="d">2016</subfield><subfield code="d">the official journal of the Anaerobe Society of the Americas</subfield><subfield code="g">London</subfield><subfield code="w">(DE-627)ELV019616112</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:42</subfield><subfield code="g">year:2016</subfield><subfield code="g">pages:101-107</subfield><subfield code="g">extent:7</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://doi.org/10.1016/j.anaerobe.2016.09.009</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_U</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ELV</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SYSFLAG_U</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_70</subfield></datafield><datafield tag="936" ind1="b" ind2="k"><subfield code="a">53.70</subfield><subfield code="j">Nachrichtentechnik</subfield><subfield code="j">Kommunikationstechnik: Allgemeines</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="936" ind1="b" ind2="k"><subfield code="a">05.42</subfield><subfield code="j">Telekommunikation</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="936" ind1="b" ind2="k"><subfield code="a">53.76</subfield><subfield code="j">Kommunikationsdienste</subfield><subfield code="j">Fernmeldetechnik</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="936" ind1="b" ind2="k"><subfield code="a">54.00</subfield><subfield code="j">Informatik: Allgemeines</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">42</subfield><subfield code="j">2016</subfield><subfield code="h">101-107</subfield><subfield code="g">7</subfield></datafield><datafield tag="953" ind1=" " ind2=" "><subfield code="2">045F</subfield><subfield code="a">570</subfield></datafield></record></collection>
|
| author |
Rodríguez-Sánchez, Belén |
| spellingShingle |
Rodríguez-Sánchez, Belén ddc 570 ddc 610 ddc 540 ddc 004 bkl 53.70 bkl 05.42 bkl 53.76 bkl 54.00 Elsevier MALDI-TOF MS Elsevier Routine identification Elsevier Anaerobic isolates Evaluation of MALDI-TOF MS (Matrix-Assisted Laser Desorption-Ionization Time-of-Flight Mass Spectrometry) for routine identification of anaerobic bacteria |
| authorStr |
Rodríguez-Sánchez, Belén |
| ppnlink_with_tag_str_mv |
@@773@@(DE-627)ELV019616112 |
| format |
electronic Article |
| dewey-ones |
570 - Life sciences; biology 610 - Medicine & health 540 - Chemistry & allied sciences 004 - Data processing & computer science |
| delete_txt_mv |
keep |
| author_role |
aut |
| collection |
elsevier |
| remote_str |
true |
| illustrated |
Not Illustrated |
| topic_title |
570 610 570 DE-600 610 DE-600 540 VZ 610 VZ 004 VZ 53.70 bkl 05.42 bkl 53.76 bkl 54.00 bkl Evaluation of MALDI-TOF MS (Matrix-Assisted Laser Desorption-Ionization Time-of-Flight Mass Spectrometry) for routine identification of anaerobic bacteria MALDI-TOF MS Elsevier Routine identification Elsevier Anaerobic isolates Elsevier |
| topic |
ddc 570 ddc 610 ddc 540 ddc 004 bkl 53.70 bkl 05.42 bkl 53.76 bkl 54.00 Elsevier MALDI-TOF MS Elsevier Routine identification Elsevier Anaerobic isolates |
| topic_unstemmed |
ddc 570 ddc 610 ddc 540 ddc 004 bkl 53.70 bkl 05.42 bkl 53.76 bkl 54.00 Elsevier MALDI-TOF MS Elsevier Routine identification Elsevier Anaerobic isolates |
| topic_browse |
ddc 570 ddc 610 ddc 540 ddc 004 bkl 53.70 bkl 05.42 bkl 53.76 bkl 54.00 Elsevier MALDI-TOF MS Elsevier Routine identification Elsevier Anaerobic isolates |
| format_facet |
Elektronische Aufsätze Aufsätze Elektronische Ressource |
| format_main_str_mv |
Text Zeitschrift/Artikel |
| carriertype_str_mv |
zu |
| author2_variant |
l a la m m mm a r ar e a ea e b eb |
| hierarchy_parent_title |
Design, synthesis and biological evaluation of 5-amino-4-(1H-benzoimidazol-2-yl)-phenyl-1,2-dihydro-pyrrol-3-ones as inhibitors of protein kinase FGFR1 |
| hierarchy_parent_id |
ELV019616112 |
| dewey-tens |
570 - Life sciences; biology 610 - Medicine & health 540 - Chemistry 000 - Computer science, knowledge & systems |
| hierarchy_top_title |
Design, synthesis and biological evaluation of 5-amino-4-(1H-benzoimidazol-2-yl)-phenyl-1,2-dihydro-pyrrol-3-ones as inhibitors of protein kinase FGFR1 |
| isfreeaccess_txt |
false |
| familylinks_str_mv |
(DE-627)ELV019616112 |
| title |
Evaluation of MALDI-TOF MS (Matrix-Assisted Laser Desorption-Ionization Time-of-Flight Mass Spectrometry) for routine identification of anaerobic bacteria |
| ctrlnum |
(DE-627)ELV029968720 (ELSEVIER)S1075-9964(16)30118-4 |
| title_full |
Evaluation of MALDI-TOF MS (Matrix-Assisted Laser Desorption-Ionization Time-of-Flight Mass Spectrometry) for routine identification of anaerobic bacteria |
| author_sort |
Rodríguez-Sánchez, Belén |
| journal |
Design, synthesis and biological evaluation of 5-amino-4-(1H-benzoimidazol-2-yl)-phenyl-1,2-dihydro-pyrrol-3-ones as inhibitors of protein kinase FGFR1 |
| journalStr |
Design, synthesis and biological evaluation of 5-amino-4-(1H-benzoimidazol-2-yl)-phenyl-1,2-dihydro-pyrrol-3-ones as inhibitors of protein kinase FGFR1 |
| lang_code |
eng |
| isOA_bool |
false |
| dewey-hundreds |
500 - Science 600 - Technology 000 - Computer science, information & general works |
| recordtype |
marc |
| publishDateSort |
2016 |
| contenttype_str_mv |
zzz |
| container_start_page |
101 |
| author_browse |
Rodríguez-Sánchez, Belén |
| container_volume |
42 |
| physical |
7 |
| class |
570 610 570 DE-600 610 DE-600 540 VZ 610 VZ 004 VZ 53.70 bkl 05.42 bkl 53.76 bkl 54.00 bkl |
| format_se |
Elektronische Aufsätze |
| author-letter |
Rodríguez-Sánchez, Belén |
| doi_str_mv |
10.1016/j.anaerobe.2016.09.009 |
| dewey-full |
570 610 540 004 |
| title_sort |
evaluation of maldi-tof ms (matrix-assisted laser desorption-ionization time-of-flight mass spectrometry) for routine identification of anaerobic bacteria |
| title_auth |
Evaluation of MALDI-TOF MS (Matrix-Assisted Laser Desorption-Ionization Time-of-Flight Mass Spectrometry) for routine identification of anaerobic bacteria |
| abstract |
Information regarding the use of MALDI-TOF MS as an alternative to conventional laboratory methods for the rapid and reliable identification of bacterial isolates is still limited. In this study, MALDI-TOF MS was evaluated on 295 anaerobic isolates previously identified by 16S rRNA gene sequencing and with biochemical tests (Rapid ID 32A system, BioMérieux). In total, 85.8% of the isolates were identified by MALDI-TOF MS at the species level vs 49.8% using the Rapid ID 32A system (p < 0.0001). None of the isolates was discordantly identified at the genus level using MALDI-TOF MS and only 9 of them could not be identified using the method. Thus, our results show that MALDI-TOF MS is a robust and reliable tool for the identification of anaerobic isolates in the microbiology laboratory. Its implementation will reduce the turnaround time for a final identification and the number of isolates that require 16S rRNA sequencing. |
| abstractGer |
Information regarding the use of MALDI-TOF MS as an alternative to conventional laboratory methods for the rapid and reliable identification of bacterial isolates is still limited. In this study, MALDI-TOF MS was evaluated on 295 anaerobic isolates previously identified by 16S rRNA gene sequencing and with biochemical tests (Rapid ID 32A system, BioMérieux). In total, 85.8% of the isolates were identified by MALDI-TOF MS at the species level vs 49.8% using the Rapid ID 32A system (p < 0.0001). None of the isolates was discordantly identified at the genus level using MALDI-TOF MS and only 9 of them could not be identified using the method. Thus, our results show that MALDI-TOF MS is a robust and reliable tool for the identification of anaerobic isolates in the microbiology laboratory. Its implementation will reduce the turnaround time for a final identification and the number of isolates that require 16S rRNA sequencing. |
| abstract_unstemmed |
Information regarding the use of MALDI-TOF MS as an alternative to conventional laboratory methods for the rapid and reliable identification of bacterial isolates is still limited. In this study, MALDI-TOF MS was evaluated on 295 anaerobic isolates previously identified by 16S rRNA gene sequencing and with biochemical tests (Rapid ID 32A system, BioMérieux). In total, 85.8% of the isolates were identified by MALDI-TOF MS at the species level vs 49.8% using the Rapid ID 32A system (p < 0.0001). None of the isolates was discordantly identified at the genus level using MALDI-TOF MS and only 9 of them could not be identified using the method. Thus, our results show that MALDI-TOF MS is a robust and reliable tool for the identification of anaerobic isolates in the microbiology laboratory. Its implementation will reduce the turnaround time for a final identification and the number of isolates that require 16S rRNA sequencing. |
| collection_details |
GBV_USEFLAG_U GBV_ELV SYSFLAG_U GBV_ILN_70 |
| title_short |
Evaluation of MALDI-TOF MS (Matrix-Assisted Laser Desorption-Ionization Time-of-Flight Mass Spectrometry) for routine identification of anaerobic bacteria |
| url |
https://doi.org/10.1016/j.anaerobe.2016.09.009 |
| remote_bool |
true |
| author2 |
Alcalá, Luis Marín, Mercedes Ruiz, Adrián Alonso, Elena Bouza, Emilio |
| author2Str |
Alcalá, Luis Marín, Mercedes Ruiz, Adrián Alonso, Elena Bouza, Emilio |
| ppnlink |
ELV019616112 |
| mediatype_str_mv |
z |
| isOA_txt |
false |
| hochschulschrift_bool |
false |
| author2_role |
oth oth oth oth oth |
| doi_str |
10.1016/j.anaerobe.2016.09.009 |
| up_date |
2024-07-06T22:51:06.465Z |
| _version_ |
1803871863666900992 |
| fullrecord_marcxml |
<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">ELV029968720</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230625180052.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">180603s2016 xx |||||o 00| ||eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1016/j.anaerobe.2016.09.009</subfield><subfield code="2">doi</subfield></datafield><datafield tag="028" ind1="5" ind2="2"><subfield code="a">GBV00000000000087A.pica</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)ELV029968720</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(ELSEVIER)S1075-9964(16)30118-4</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="082" ind1="0" ind2=" "><subfield code="a">570</subfield><subfield code="a">610</subfield></datafield><datafield tag="082" ind1="0" ind2="4"><subfield code="a">570</subfield><subfield code="q">DE-600</subfield></datafield><datafield tag="082" ind1="0" ind2="4"><subfield code="a">610</subfield><subfield code="q">DE-600</subfield></datafield><datafield tag="082" ind1="0" ind2="4"><subfield code="a">540</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="082" ind1="0" ind2="4"><subfield code="a">610</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="082" ind1="0" ind2="4"><subfield code="a">004</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">53.70</subfield><subfield code="2">bkl</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">05.42</subfield><subfield code="2">bkl</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">53.76</subfield><subfield code="2">bkl</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">54.00</subfield><subfield code="2">bkl</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Rodríguez-Sánchez, Belén</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Evaluation of MALDI-TOF MS (Matrix-Assisted Laser Desorption-Ionization Time-of-Flight Mass Spectrometry) for routine identification of anaerobic bacteria</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2016transfer abstract</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">7</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zzz</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">z</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zu</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Information regarding the use of MALDI-TOF MS as an alternative to conventional laboratory methods for the rapid and reliable identification of bacterial isolates is still limited. In this study, MALDI-TOF MS was evaluated on 295 anaerobic isolates previously identified by 16S rRNA gene sequencing and with biochemical tests (Rapid ID 32A system, BioMérieux). In total, 85.8% of the isolates were identified by MALDI-TOF MS at the species level vs 49.8% using the Rapid ID 32A system (p < 0.0001). None of the isolates was discordantly identified at the genus level using MALDI-TOF MS and only 9 of them could not be identified using the method. Thus, our results show that MALDI-TOF MS is a robust and reliable tool for the identification of anaerobic isolates in the microbiology laboratory. Its implementation will reduce the turnaround time for a final identification and the number of isolates that require 16S rRNA sequencing.</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Information regarding the use of MALDI-TOF MS as an alternative to conventional laboratory methods for the rapid and reliable identification of bacterial isolates is still limited. In this study, MALDI-TOF MS was evaluated on 295 anaerobic isolates previously identified by 16S rRNA gene sequencing and with biochemical tests (Rapid ID 32A system, BioMérieux). In total, 85.8% of the isolates were identified by MALDI-TOF MS at the species level vs 49.8% using the Rapid ID 32A system (p < 0.0001). None of the isolates was discordantly identified at the genus level using MALDI-TOF MS and only 9 of them could not be identified using the method. Thus, our results show that MALDI-TOF MS is a robust and reliable tool for the identification of anaerobic isolates in the microbiology laboratory. Its implementation will reduce the turnaround time for a final identification and the number of isolates that require 16S rRNA sequencing.</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">MALDI-TOF MS</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Routine identification</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Anaerobic isolates</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Alcalá, Luis</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Marín, Mercedes</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Ruiz, Adrián</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Alonso, Elena</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Bouza, Emilio</subfield><subfield code="4">oth</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">Enthalten in</subfield><subfield code="n">Academic Press</subfield><subfield code="a">Gryshchenko, A.A. ELSEVIER</subfield><subfield code="t">Design, synthesis and biological evaluation of 5-amino-4-(1H-benzoimidazol-2-yl)-phenyl-1,2-dihydro-pyrrol-3-ones as inhibitors of protein kinase FGFR1</subfield><subfield code="d">2016</subfield><subfield code="d">the official journal of the Anaerobe Society of the Americas</subfield><subfield code="g">London</subfield><subfield code="w">(DE-627)ELV019616112</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:42</subfield><subfield code="g">year:2016</subfield><subfield code="g">pages:101-107</subfield><subfield code="g">extent:7</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://doi.org/10.1016/j.anaerobe.2016.09.009</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_U</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ELV</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SYSFLAG_U</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_70</subfield></datafield><datafield tag="936" ind1="b" ind2="k"><subfield code="a">53.70</subfield><subfield code="j">Nachrichtentechnik</subfield><subfield code="j">Kommunikationstechnik: Allgemeines</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="936" ind1="b" ind2="k"><subfield code="a">05.42</subfield><subfield code="j">Telekommunikation</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="936" ind1="b" ind2="k"><subfield code="a">53.76</subfield><subfield code="j">Kommunikationsdienste</subfield><subfield code="j">Fernmeldetechnik</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="936" ind1="b" ind2="k"><subfield code="a">54.00</subfield><subfield code="j">Informatik: Allgemeines</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">42</subfield><subfield code="j">2016</subfield><subfield code="h">101-107</subfield><subfield code="g">7</subfield></datafield><datafield tag="953" ind1=" " ind2=" "><subfield code="2">045F</subfield><subfield code="a">570</subfield></datafield></record></collection>
|
| score |
7.401 |