Increase of circulating α4β7+ conventional memory CD4 and regulatory T cells in patients with common variable immunodeficiency (CVID)
This study investigated whether circulating α4β7+ expressing T cells could serve as a potential marker for gastrointestinal (GI) disease activity in patients with CVID. The analysis of α4β7+ T cells in the peripheral blood of 36 patients and 22 healthy donors (HD) revealed increased percentages of α...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
de Melo, Karina Mescouto [verfasserIn] |
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| Format: |
E-Artikel |
|---|---|
| Sprache: |
Englisch |
| Erschienen: |
2017transfer abstract |
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| Umfang: |
4 |
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| Übergeordnetes Werk: |
Enthalten in: Comorbid episodes of primary bruxism and bruxism as an epileptic activity-related motor event - Bušková, Jitka ELSEVIER, 2019, San Diego, Calif |
|---|---|
| Übergeordnetes Werk: |
volume:180 ; year:2017 ; pages:80-83 ; extent:4 |
| Links: |
|---|
| DOI / URN: |
10.1016/j.clim.2017.03.006 |
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ELV030309646 |
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| 245 | 1 | 0 | |a Increase of circulating α4β7+ conventional memory CD4 and regulatory T cells in patients with common variable immunodeficiency (CVID) |
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| 520 | |a This study investigated whether circulating α4β7+ expressing T cells could serve as a potential marker for gastrointestinal (GI) disease activity in patients with CVID. The analysis of α4β7+ T cells in the peripheral blood of 36 patients and 22 healthy donors (HD) revealed increased percentages of α4β7+ conventional memory CD4 T cells and Tregs, but not among CD8 T-cell populations in patients with CVID compared to HD. No differences between patients with and without chronic or acute GI symptoms were observed. EUROClass smB− and 21lo patients, had higher percentages of α4β7+ memory CD4 T cells compared to HD and smB+ or 21norm patients, respectively. In summary, the detection of α4β7+ T cells in the peripheral blood did not correlate with active or chronic gastrointestinal disease. The increase of these cells in smB− and 21lo patients adds another piece to the immune dysregulation observed in these patients. | ||
| 520 | |a This study investigated whether circulating α4β7+ expressing T cells could serve as a potential marker for gastrointestinal (GI) disease activity in patients with CVID. The analysis of α4β7+ T cells in the peripheral blood of 36 patients and 22 healthy donors (HD) revealed increased percentages of α4β7+ conventional memory CD4 T cells and Tregs, but not among CD8 T-cell populations in patients with CVID compared to HD. No differences between patients with and without chronic or acute GI symptoms were observed. EUROClass smB− and 21lo patients, had higher percentages of α4β7+ memory CD4 T cells compared to HD and smB+ or 21norm patients, respectively. In summary, the detection of α4β7+ T cells in the peripheral blood did not correlate with active or chronic gastrointestinal disease. The increase of these cells in smB− and 21lo patients adds another piece to the immune dysregulation observed in these patients. | ||
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| 700 | 1 | |a Stumpf, Ina |4 oth | |
| 700 | 1 | |a Goldacker, Sigune |4 oth | |
| 700 | 1 | |a Warnatz, Klaus |4 oth | |
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10.1016/j.clim.2017.03.006 doi GBV00000000000123A.pica (DE-627)ELV030309646 (ELSEVIER)S1521-6616(16)30521-6 DE-627 ger DE-627 rakwb eng 610 610 DE-600 610 VZ 44.90 bkl de Melo, Karina Mescouto verfasserin aut Increase of circulating α4β7+ conventional memory CD4 and regulatory T cells in patients with common variable immunodeficiency (CVID) 2017transfer abstract 4 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier This study investigated whether circulating α4β7+ expressing T cells could serve as a potential marker for gastrointestinal (GI) disease activity in patients with CVID. The analysis of α4β7+ T cells in the peripheral blood of 36 patients and 22 healthy donors (HD) revealed increased percentages of α4β7+ conventional memory CD4 T cells and Tregs, but not among CD8 T-cell populations in patients with CVID compared to HD. No differences between patients with and without chronic or acute GI symptoms were observed. EUROClass smB− and 21lo patients, had higher percentages of α4β7+ memory CD4 T cells compared to HD and smB+ or 21norm patients, respectively. In summary, the detection of α4β7+ T cells in the peripheral blood did not correlate with active or chronic gastrointestinal disease. The increase of these cells in smB− and 21lo patients adds another piece to the immune dysregulation observed in these patients. This study investigated whether circulating α4β7+ expressing T cells could serve as a potential marker for gastrointestinal (GI) disease activity in patients with CVID. The analysis of α4β7+ T cells in the peripheral blood of 36 patients and 22 healthy donors (HD) revealed increased percentages of α4β7+ conventional memory CD4 T cells and Tregs, but not among CD8 T-cell populations in patients with CVID compared to HD. No differences between patients with and without chronic or acute GI symptoms were observed. EUROClass smB− and 21lo patients, had higher percentages of α4β7+ memory CD4 T cells compared to HD and smB+ or 21norm patients, respectively. In summary, the detection of α4β7+ T cells in the peripheral blood did not correlate with active or chronic gastrointestinal disease. The increase of these cells in smB− and 21lo patients adds another piece to the immune dysregulation observed in these patients. Unger, Susanne oth Keller, Baerbel oth Gutenberger, Sylvia oth Stumpf, Ina oth Goldacker, Sigune oth Warnatz, Klaus oth Enthalten in Elsevier Bušková, Jitka ELSEVIER Comorbid episodes of primary bruxism and bruxism as an epileptic activity-related motor event 2019 San Diego, Calif (DE-627)ELV003196453 volume:180 year:2017 pages:80-83 extent:4 https://doi.org/10.1016/j.clim.2017.03.006 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 44.90 Neurologie VZ AR 180 2017 80-83 4 045F 610 |
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10.1016/j.clim.2017.03.006 doi GBV00000000000123A.pica (DE-627)ELV030309646 (ELSEVIER)S1521-6616(16)30521-6 DE-627 ger DE-627 rakwb eng 610 610 DE-600 610 VZ 44.90 bkl de Melo, Karina Mescouto verfasserin aut Increase of circulating α4β7+ conventional memory CD4 and regulatory T cells in patients with common variable immunodeficiency (CVID) 2017transfer abstract 4 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier This study investigated whether circulating α4β7+ expressing T cells could serve as a potential marker for gastrointestinal (GI) disease activity in patients with CVID. The analysis of α4β7+ T cells in the peripheral blood of 36 patients and 22 healthy donors (HD) revealed increased percentages of α4β7+ conventional memory CD4 T cells and Tregs, but not among CD8 T-cell populations in patients with CVID compared to HD. No differences between patients with and without chronic or acute GI symptoms were observed. EUROClass smB− and 21lo patients, had higher percentages of α4β7+ memory CD4 T cells compared to HD and smB+ or 21norm patients, respectively. In summary, the detection of α4β7+ T cells in the peripheral blood did not correlate with active or chronic gastrointestinal disease. The increase of these cells in smB− and 21lo patients adds another piece to the immune dysregulation observed in these patients. This study investigated whether circulating α4β7+ expressing T cells could serve as a potential marker for gastrointestinal (GI) disease activity in patients with CVID. The analysis of α4β7+ T cells in the peripheral blood of 36 patients and 22 healthy donors (HD) revealed increased percentages of α4β7+ conventional memory CD4 T cells and Tregs, but not among CD8 T-cell populations in patients with CVID compared to HD. No differences between patients with and without chronic or acute GI symptoms were observed. EUROClass smB− and 21lo patients, had higher percentages of α4β7+ memory CD4 T cells compared to HD and smB+ or 21norm patients, respectively. In summary, the detection of α4β7+ T cells in the peripheral blood did not correlate with active or chronic gastrointestinal disease. The increase of these cells in smB− and 21lo patients adds another piece to the immune dysregulation observed in these patients. Unger, Susanne oth Keller, Baerbel oth Gutenberger, Sylvia oth Stumpf, Ina oth Goldacker, Sigune oth Warnatz, Klaus oth Enthalten in Elsevier Bušková, Jitka ELSEVIER Comorbid episodes of primary bruxism and bruxism as an epileptic activity-related motor event 2019 San Diego, Calif (DE-627)ELV003196453 volume:180 year:2017 pages:80-83 extent:4 https://doi.org/10.1016/j.clim.2017.03.006 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 44.90 Neurologie VZ AR 180 2017 80-83 4 045F 610 |
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10.1016/j.clim.2017.03.006 doi GBV00000000000123A.pica (DE-627)ELV030309646 (ELSEVIER)S1521-6616(16)30521-6 DE-627 ger DE-627 rakwb eng 610 610 DE-600 610 VZ 44.90 bkl de Melo, Karina Mescouto verfasserin aut Increase of circulating α4β7+ conventional memory CD4 and regulatory T cells in patients with common variable immunodeficiency (CVID) 2017transfer abstract 4 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier This study investigated whether circulating α4β7+ expressing T cells could serve as a potential marker for gastrointestinal (GI) disease activity in patients with CVID. The analysis of α4β7+ T cells in the peripheral blood of 36 patients and 22 healthy donors (HD) revealed increased percentages of α4β7+ conventional memory CD4 T cells and Tregs, but not among CD8 T-cell populations in patients with CVID compared to HD. No differences between patients with and without chronic or acute GI symptoms were observed. EUROClass smB− and 21lo patients, had higher percentages of α4β7+ memory CD4 T cells compared to HD and smB+ or 21norm patients, respectively. In summary, the detection of α4β7+ T cells in the peripheral blood did not correlate with active or chronic gastrointestinal disease. The increase of these cells in smB− and 21lo patients adds another piece to the immune dysregulation observed in these patients. This study investigated whether circulating α4β7+ expressing T cells could serve as a potential marker for gastrointestinal (GI) disease activity in patients with CVID. The analysis of α4β7+ T cells in the peripheral blood of 36 patients and 22 healthy donors (HD) revealed increased percentages of α4β7+ conventional memory CD4 T cells and Tregs, but not among CD8 T-cell populations in patients with CVID compared to HD. No differences between patients with and without chronic or acute GI symptoms were observed. EUROClass smB− and 21lo patients, had higher percentages of α4β7+ memory CD4 T cells compared to HD and smB+ or 21norm patients, respectively. In summary, the detection of α4β7+ T cells in the peripheral blood did not correlate with active or chronic gastrointestinal disease. The increase of these cells in smB− and 21lo patients adds another piece to the immune dysregulation observed in these patients. Unger, Susanne oth Keller, Baerbel oth Gutenberger, Sylvia oth Stumpf, Ina oth Goldacker, Sigune oth Warnatz, Klaus oth Enthalten in Elsevier Bušková, Jitka ELSEVIER Comorbid episodes of primary bruxism and bruxism as an epileptic activity-related motor event 2019 San Diego, Calif (DE-627)ELV003196453 volume:180 year:2017 pages:80-83 extent:4 https://doi.org/10.1016/j.clim.2017.03.006 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 44.90 Neurologie VZ AR 180 2017 80-83 4 045F 610 |
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10.1016/j.clim.2017.03.006 doi GBV00000000000123A.pica (DE-627)ELV030309646 (ELSEVIER)S1521-6616(16)30521-6 DE-627 ger DE-627 rakwb eng 610 610 DE-600 610 VZ 44.90 bkl de Melo, Karina Mescouto verfasserin aut Increase of circulating α4β7+ conventional memory CD4 and regulatory T cells in patients with common variable immunodeficiency (CVID) 2017transfer abstract 4 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier This study investigated whether circulating α4β7+ expressing T cells could serve as a potential marker for gastrointestinal (GI) disease activity in patients with CVID. The analysis of α4β7+ T cells in the peripheral blood of 36 patients and 22 healthy donors (HD) revealed increased percentages of α4β7+ conventional memory CD4 T cells and Tregs, but not among CD8 T-cell populations in patients with CVID compared to HD. No differences between patients with and without chronic or acute GI symptoms were observed. EUROClass smB− and 21lo patients, had higher percentages of α4β7+ memory CD4 T cells compared to HD and smB+ or 21norm patients, respectively. In summary, the detection of α4β7+ T cells in the peripheral blood did not correlate with active or chronic gastrointestinal disease. The increase of these cells in smB− and 21lo patients adds another piece to the immune dysregulation observed in these patients. This study investigated whether circulating α4β7+ expressing T cells could serve as a potential marker for gastrointestinal (GI) disease activity in patients with CVID. The analysis of α4β7+ T cells in the peripheral blood of 36 patients and 22 healthy donors (HD) revealed increased percentages of α4β7+ conventional memory CD4 T cells and Tregs, but not among CD8 T-cell populations in patients with CVID compared to HD. No differences between patients with and without chronic or acute GI symptoms were observed. EUROClass smB− and 21lo patients, had higher percentages of α4β7+ memory CD4 T cells compared to HD and smB+ or 21norm patients, respectively. In summary, the detection of α4β7+ T cells in the peripheral blood did not correlate with active or chronic gastrointestinal disease. The increase of these cells in smB− and 21lo patients adds another piece to the immune dysregulation observed in these patients. Unger, Susanne oth Keller, Baerbel oth Gutenberger, Sylvia oth Stumpf, Ina oth Goldacker, Sigune oth Warnatz, Klaus oth Enthalten in Elsevier Bušková, Jitka ELSEVIER Comorbid episodes of primary bruxism and bruxism as an epileptic activity-related motor event 2019 San Diego, Calif (DE-627)ELV003196453 volume:180 year:2017 pages:80-83 extent:4 https://doi.org/10.1016/j.clim.2017.03.006 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 44.90 Neurologie VZ AR 180 2017 80-83 4 045F 610 |
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10.1016/j.clim.2017.03.006 doi GBV00000000000123A.pica (DE-627)ELV030309646 (ELSEVIER)S1521-6616(16)30521-6 DE-627 ger DE-627 rakwb eng 610 610 DE-600 610 VZ 44.90 bkl de Melo, Karina Mescouto verfasserin aut Increase of circulating α4β7+ conventional memory CD4 and regulatory T cells in patients with common variable immunodeficiency (CVID) 2017transfer abstract 4 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier This study investigated whether circulating α4β7+ expressing T cells could serve as a potential marker for gastrointestinal (GI) disease activity in patients with CVID. The analysis of α4β7+ T cells in the peripheral blood of 36 patients and 22 healthy donors (HD) revealed increased percentages of α4β7+ conventional memory CD4 T cells and Tregs, but not among CD8 T-cell populations in patients with CVID compared to HD. No differences between patients with and without chronic or acute GI symptoms were observed. EUROClass smB− and 21lo patients, had higher percentages of α4β7+ memory CD4 T cells compared to HD and smB+ or 21norm patients, respectively. In summary, the detection of α4β7+ T cells in the peripheral blood did not correlate with active or chronic gastrointestinal disease. The increase of these cells in smB− and 21lo patients adds another piece to the immune dysregulation observed in these patients. This study investigated whether circulating α4β7+ expressing T cells could serve as a potential marker for gastrointestinal (GI) disease activity in patients with CVID. The analysis of α4β7+ T cells in the peripheral blood of 36 patients and 22 healthy donors (HD) revealed increased percentages of α4β7+ conventional memory CD4 T cells and Tregs, but not among CD8 T-cell populations in patients with CVID compared to HD. No differences between patients with and without chronic or acute GI symptoms were observed. EUROClass smB− and 21lo patients, had higher percentages of α4β7+ memory CD4 T cells compared to HD and smB+ or 21norm patients, respectively. In summary, the detection of α4β7+ T cells in the peripheral blood did not correlate with active or chronic gastrointestinal disease. The increase of these cells in smB− and 21lo patients adds another piece to the immune dysregulation observed in these patients. Unger, Susanne oth Keller, Baerbel oth Gutenberger, Sylvia oth Stumpf, Ina oth Goldacker, Sigune oth Warnatz, Klaus oth Enthalten in Elsevier Bušková, Jitka ELSEVIER Comorbid episodes of primary bruxism and bruxism as an epileptic activity-related motor event 2019 San Diego, Calif (DE-627)ELV003196453 volume:180 year:2017 pages:80-83 extent:4 https://doi.org/10.1016/j.clim.2017.03.006 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 44.90 Neurologie VZ AR 180 2017 80-83 4 045F 610 |
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Enthalten in Comorbid episodes of primary bruxism and bruxism as an epileptic activity-related motor event San Diego, Calif volume:180 year:2017 pages:80-83 extent:4 |
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Comorbid episodes of primary bruxism and bruxism as an epileptic activity-related motor event |
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de Melo, Karina Mescouto @@aut@@ Unger, Susanne @@oth@@ Keller, Baerbel @@oth@@ Gutenberger, Sylvia @@oth@@ Stumpf, Ina @@oth@@ Goldacker, Sigune @@oth@@ Warnatz, Klaus @@oth@@ |
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| author |
de Melo, Karina Mescouto |
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Comorbid episodes of primary bruxism and bruxism as an epileptic activity-related motor event |
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Comorbid episodes of primary bruxism and bruxism as an epileptic activity-related motor event |
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Increase of circulating α4β7+ conventional memory CD4 and regulatory T cells in patients with common variable immunodeficiency (CVID) |
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Increase of circulating α4β7+ conventional memory CD4 and regulatory T cells in patients with common variable immunodeficiency (CVID) |
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de Melo, Karina Mescouto |
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Comorbid episodes of primary bruxism and bruxism as an epileptic activity-related motor event |
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Comorbid episodes of primary bruxism and bruxism as an epileptic activity-related motor event |
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increase of circulating α4β7+ conventional memory cd4 and regulatory t cells in patients with common variable immunodeficiency (cvid) |
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Increase of circulating α4β7+ conventional memory CD4 and regulatory T cells in patients with common variable immunodeficiency (CVID) |
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This study investigated whether circulating α4β7+ expressing T cells could serve as a potential marker for gastrointestinal (GI) disease activity in patients with CVID. The analysis of α4β7+ T cells in the peripheral blood of 36 patients and 22 healthy donors (HD) revealed increased percentages of α4β7+ conventional memory CD4 T cells and Tregs, but not among CD8 T-cell populations in patients with CVID compared to HD. No differences between patients with and without chronic or acute GI symptoms were observed. EUROClass smB− and 21lo patients, had higher percentages of α4β7+ memory CD4 T cells compared to HD and smB+ or 21norm patients, respectively. In summary, the detection of α4β7+ T cells in the peripheral blood did not correlate with active or chronic gastrointestinal disease. The increase of these cells in smB− and 21lo patients adds another piece to the immune dysregulation observed in these patients. |
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This study investigated whether circulating α4β7+ expressing T cells could serve as a potential marker for gastrointestinal (GI) disease activity in patients with CVID. The analysis of α4β7+ T cells in the peripheral blood of 36 patients and 22 healthy donors (HD) revealed increased percentages of α4β7+ conventional memory CD4 T cells and Tregs, but not among CD8 T-cell populations in patients with CVID compared to HD. No differences between patients with and without chronic or acute GI symptoms were observed. EUROClass smB− and 21lo patients, had higher percentages of α4β7+ memory CD4 T cells compared to HD and smB+ or 21norm patients, respectively. In summary, the detection of α4β7+ T cells in the peripheral blood did not correlate with active or chronic gastrointestinal disease. The increase of these cells in smB− and 21lo patients adds another piece to the immune dysregulation observed in these patients. |
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This study investigated whether circulating α4β7+ expressing T cells could serve as a potential marker for gastrointestinal (GI) disease activity in patients with CVID. The analysis of α4β7+ T cells in the peripheral blood of 36 patients and 22 healthy donors (HD) revealed increased percentages of α4β7+ conventional memory CD4 T cells and Tregs, but not among CD8 T-cell populations in patients with CVID compared to HD. No differences between patients with and without chronic or acute GI symptoms were observed. EUROClass smB− and 21lo patients, had higher percentages of α4β7+ memory CD4 T cells compared to HD and smB+ or 21norm patients, respectively. In summary, the detection of α4β7+ T cells in the peripheral blood did not correlate with active or chronic gastrointestinal disease. The increase of these cells in smB− and 21lo patients adds another piece to the immune dysregulation observed in these patients. |
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Increase of circulating α4β7+ conventional memory CD4 and regulatory T cells in patients with common variable immunodeficiency (CVID) |
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Unger, Susanne Keller, Baerbel Gutenberger, Sylvia Stumpf, Ina Goldacker, Sigune Warnatz, Klaus |
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