Alarmins firing arthritis: Helpful diagnostic tools and promising therapeutic targets
Alarmins are endogenous molecules with homeostatic roles that have reached the focus of research in inflammatory arthritis in the last two decades, mostly due to their ability to indicate tissue related damage after active or passive release from injured cells. From HMGB1, S100A8/A9 and S100A12 prot...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Lavric, Miha [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2017transfer abstract |
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| Schlagwörter: |
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| Umfang: |
10 |
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| Übergeordnetes Werk: |
Enthalten in: Calendar of Events - 2014, revue du rhumatisme, international edition : official publication of the French Society of Rheumatology, Paris |
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| Übergeordnetes Werk: |
volume:84 ; year:2017 ; number:4 ; pages:401-410 ; extent:10 |
| Links: |
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| DOI / URN: |
10.1016/j.jbspin.2016.06.010 |
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ELV030693683 |
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| 520 | |a Alarmins are endogenous molecules with homeostatic roles that have reached the focus of research in inflammatory arthritis in the last two decades, mostly due to their ability to indicate tissue related damage after active or passive release from injured cells. From HMGB1, S100A8/A9 and S100A12 proteins, over heat-shock proteins (HSPs) and purine metabolites (e.g. uric acid, ATP) to altered matrix proteins and interleukin-33 (IL-33), a number of alarmins have been determined until now as having a role in rheumatoid arthritis, psoriatic and juvenile idiopathic arthritis, as well as spondyloarthritis and gout. Although formerly being linked to initiation and chronification of inflammatory arthritis, driving auto- and paracrine inflammatory loops, more recent research has also unraveled the alarmins’ role in the crosstalk between innate and adaptive immunity and in resolution of inflammation. | ||
| 520 | |a Alarmins are endogenous molecules with homeostatic roles that have reached the focus of research in inflammatory arthritis in the last two decades, mostly due to their ability to indicate tissue related damage after active or passive release from injured cells. From HMGB1, S100A8/A9 and S100A12 proteins, over heat-shock proteins (HSPs) and purine metabolites (e.g. uric acid, ATP) to altered matrix proteins and interleukin-33 (IL-33), a number of alarmins have been determined until now as having a role in rheumatoid arthritis, psoriatic and juvenile idiopathic arthritis, as well as spondyloarthritis and gout. Although formerly being linked to initiation and chronification of inflammatory arthritis, driving auto- and paracrine inflammatory loops, more recent research has also unraveled the alarmins’ role in the crosstalk between innate and adaptive immunity and in resolution of inflammation. | ||
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10.1016/j.jbspin.2016.06.010 doi GBVA2017018000013.pica (DE-627)ELV030693683 (ELSEVIER)S1297-319X(16)30127-0 DE-627 ger DE-627 rakwb eng 610 610 DE-600 610 VZ 540 VZ 35.10 bkl Lavric, Miha verfasserin aut Alarmins firing arthritis: Helpful diagnostic tools and promising therapeutic targets 2017transfer abstract 10 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Alarmins are endogenous molecules with homeostatic roles that have reached the focus of research in inflammatory arthritis in the last two decades, mostly due to their ability to indicate tissue related damage after active or passive release from injured cells. From HMGB1, S100A8/A9 and S100A12 proteins, over heat-shock proteins (HSPs) and purine metabolites (e.g. uric acid, ATP) to altered matrix proteins and interleukin-33 (IL-33), a number of alarmins have been determined until now as having a role in rheumatoid arthritis, psoriatic and juvenile idiopathic arthritis, as well as spondyloarthritis and gout. Although formerly being linked to initiation and chronification of inflammatory arthritis, driving auto- and paracrine inflammatory loops, more recent research has also unraveled the alarmins’ role in the crosstalk between innate and adaptive immunity and in resolution of inflammation. Alarmins are endogenous molecules with homeostatic roles that have reached the focus of research in inflammatory arthritis in the last two decades, mostly due to their ability to indicate tissue related damage after active or passive release from injured cells. From HMGB1, S100A8/A9 and S100A12 proteins, over heat-shock proteins (HSPs) and purine metabolites (e.g. uric acid, ATP) to altered matrix proteins and interleukin-33 (IL-33), a number of alarmins have been determined until now as having a role in rheumatoid arthritis, psoriatic and juvenile idiopathic arthritis, as well as spondyloarthritis and gout. Although formerly being linked to initiation and chronification of inflammatory arthritis, driving auto- and paracrine inflammatory loops, more recent research has also unraveled the alarmins’ role in the crosstalk between innate and adaptive immunity and in resolution of inflammation. Alarmins Elsevier Pathology Elsevier Biomarkers Elsevier Arthritis Elsevier DAMPs Elsevier Miranda-García, María Auxiliadora oth Holzinger, Dirk oth Foell, Dirk oth Wittkowski, Helmut oth Enthalten in Elsevier Calendar of Events 2014 revue du rhumatisme, international edition : official publication of the French Society of Rheumatology Paris (DE-627)ELV017983630 volume:84 year:2017 number:4 pages:401-410 extent:10 https://doi.org/10.1016/j.jbspin.2016.06.010 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 35.10 Physikalische Chemie: Allgemeines VZ AR 84 2017 4 401-410 10 045F 610 |
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10.1016/j.jbspin.2016.06.010 doi GBVA2017018000013.pica (DE-627)ELV030693683 (ELSEVIER)S1297-319X(16)30127-0 DE-627 ger DE-627 rakwb eng 610 610 DE-600 610 VZ 540 VZ 35.10 bkl Lavric, Miha verfasserin aut Alarmins firing arthritis: Helpful diagnostic tools and promising therapeutic targets 2017transfer abstract 10 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Alarmins are endogenous molecules with homeostatic roles that have reached the focus of research in inflammatory arthritis in the last two decades, mostly due to their ability to indicate tissue related damage after active or passive release from injured cells. From HMGB1, S100A8/A9 and S100A12 proteins, over heat-shock proteins (HSPs) and purine metabolites (e.g. uric acid, ATP) to altered matrix proteins and interleukin-33 (IL-33), a number of alarmins have been determined until now as having a role in rheumatoid arthritis, psoriatic and juvenile idiopathic arthritis, as well as spondyloarthritis and gout. Although formerly being linked to initiation and chronification of inflammatory arthritis, driving auto- and paracrine inflammatory loops, more recent research has also unraveled the alarmins’ role in the crosstalk between innate and adaptive immunity and in resolution of inflammation. Alarmins are endogenous molecules with homeostatic roles that have reached the focus of research in inflammatory arthritis in the last two decades, mostly due to their ability to indicate tissue related damage after active or passive release from injured cells. From HMGB1, S100A8/A9 and S100A12 proteins, over heat-shock proteins (HSPs) and purine metabolites (e.g. uric acid, ATP) to altered matrix proteins and interleukin-33 (IL-33), a number of alarmins have been determined until now as having a role in rheumatoid arthritis, psoriatic and juvenile idiopathic arthritis, as well as spondyloarthritis and gout. Although formerly being linked to initiation and chronification of inflammatory arthritis, driving auto- and paracrine inflammatory loops, more recent research has also unraveled the alarmins’ role in the crosstalk between innate and adaptive immunity and in resolution of inflammation. Alarmins Elsevier Pathology Elsevier Biomarkers Elsevier Arthritis Elsevier DAMPs Elsevier Miranda-García, María Auxiliadora oth Holzinger, Dirk oth Foell, Dirk oth Wittkowski, Helmut oth Enthalten in Elsevier Calendar of Events 2014 revue du rhumatisme, international edition : official publication of the French Society of Rheumatology Paris (DE-627)ELV017983630 volume:84 year:2017 number:4 pages:401-410 extent:10 https://doi.org/10.1016/j.jbspin.2016.06.010 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 35.10 Physikalische Chemie: Allgemeines VZ AR 84 2017 4 401-410 10 045F 610 |
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10.1016/j.jbspin.2016.06.010 doi GBVA2017018000013.pica (DE-627)ELV030693683 (ELSEVIER)S1297-319X(16)30127-0 DE-627 ger DE-627 rakwb eng 610 610 DE-600 610 VZ 540 VZ 35.10 bkl Lavric, Miha verfasserin aut Alarmins firing arthritis: Helpful diagnostic tools and promising therapeutic targets 2017transfer abstract 10 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Alarmins are endogenous molecules with homeostatic roles that have reached the focus of research in inflammatory arthritis in the last two decades, mostly due to their ability to indicate tissue related damage after active or passive release from injured cells. From HMGB1, S100A8/A9 and S100A12 proteins, over heat-shock proteins (HSPs) and purine metabolites (e.g. uric acid, ATP) to altered matrix proteins and interleukin-33 (IL-33), a number of alarmins have been determined until now as having a role in rheumatoid arthritis, psoriatic and juvenile idiopathic arthritis, as well as spondyloarthritis and gout. Although formerly being linked to initiation and chronification of inflammatory arthritis, driving auto- and paracrine inflammatory loops, more recent research has also unraveled the alarmins’ role in the crosstalk between innate and adaptive immunity and in resolution of inflammation. Alarmins are endogenous molecules with homeostatic roles that have reached the focus of research in inflammatory arthritis in the last two decades, mostly due to their ability to indicate tissue related damage after active or passive release from injured cells. From HMGB1, S100A8/A9 and S100A12 proteins, over heat-shock proteins (HSPs) and purine metabolites (e.g. uric acid, ATP) to altered matrix proteins and interleukin-33 (IL-33), a number of alarmins have been determined until now as having a role in rheumatoid arthritis, psoriatic and juvenile idiopathic arthritis, as well as spondyloarthritis and gout. Although formerly being linked to initiation and chronification of inflammatory arthritis, driving auto- and paracrine inflammatory loops, more recent research has also unraveled the alarmins’ role in the crosstalk between innate and adaptive immunity and in resolution of inflammation. Alarmins Elsevier Pathology Elsevier Biomarkers Elsevier Arthritis Elsevier DAMPs Elsevier Miranda-García, María Auxiliadora oth Holzinger, Dirk oth Foell, Dirk oth Wittkowski, Helmut oth Enthalten in Elsevier Calendar of Events 2014 revue du rhumatisme, international edition : official publication of the French Society of Rheumatology Paris (DE-627)ELV017983630 volume:84 year:2017 number:4 pages:401-410 extent:10 https://doi.org/10.1016/j.jbspin.2016.06.010 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 35.10 Physikalische Chemie: Allgemeines VZ AR 84 2017 4 401-410 10 045F 610 |
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10.1016/j.jbspin.2016.06.010 doi GBVA2017018000013.pica (DE-627)ELV030693683 (ELSEVIER)S1297-319X(16)30127-0 DE-627 ger DE-627 rakwb eng 610 610 DE-600 610 VZ 540 VZ 35.10 bkl Lavric, Miha verfasserin aut Alarmins firing arthritis: Helpful diagnostic tools and promising therapeutic targets 2017transfer abstract 10 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Alarmins are endogenous molecules with homeostatic roles that have reached the focus of research in inflammatory arthritis in the last two decades, mostly due to their ability to indicate tissue related damage after active or passive release from injured cells. From HMGB1, S100A8/A9 and S100A12 proteins, over heat-shock proteins (HSPs) and purine metabolites (e.g. uric acid, ATP) to altered matrix proteins and interleukin-33 (IL-33), a number of alarmins have been determined until now as having a role in rheumatoid arthritis, psoriatic and juvenile idiopathic arthritis, as well as spondyloarthritis and gout. Although formerly being linked to initiation and chronification of inflammatory arthritis, driving auto- and paracrine inflammatory loops, more recent research has also unraveled the alarmins’ role in the crosstalk between innate and adaptive immunity and in resolution of inflammation. Alarmins are endogenous molecules with homeostatic roles that have reached the focus of research in inflammatory arthritis in the last two decades, mostly due to their ability to indicate tissue related damage after active or passive release from injured cells. From HMGB1, S100A8/A9 and S100A12 proteins, over heat-shock proteins (HSPs) and purine metabolites (e.g. uric acid, ATP) to altered matrix proteins and interleukin-33 (IL-33), a number of alarmins have been determined until now as having a role in rheumatoid arthritis, psoriatic and juvenile idiopathic arthritis, as well as spondyloarthritis and gout. Although formerly being linked to initiation and chronification of inflammatory arthritis, driving auto- and paracrine inflammatory loops, more recent research has also unraveled the alarmins’ role in the crosstalk between innate and adaptive immunity and in resolution of inflammation. Alarmins Elsevier Pathology Elsevier Biomarkers Elsevier Arthritis Elsevier DAMPs Elsevier Miranda-García, María Auxiliadora oth Holzinger, Dirk oth Foell, Dirk oth Wittkowski, Helmut oth Enthalten in Elsevier Calendar of Events 2014 revue du rhumatisme, international edition : official publication of the French Society of Rheumatology Paris (DE-627)ELV017983630 volume:84 year:2017 number:4 pages:401-410 extent:10 https://doi.org/10.1016/j.jbspin.2016.06.010 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 35.10 Physikalische Chemie: Allgemeines VZ AR 84 2017 4 401-410 10 045F 610 |
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10.1016/j.jbspin.2016.06.010 doi GBVA2017018000013.pica (DE-627)ELV030693683 (ELSEVIER)S1297-319X(16)30127-0 DE-627 ger DE-627 rakwb eng 610 610 DE-600 610 VZ 540 VZ 35.10 bkl Lavric, Miha verfasserin aut Alarmins firing arthritis: Helpful diagnostic tools and promising therapeutic targets 2017transfer abstract 10 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Alarmins are endogenous molecules with homeostatic roles that have reached the focus of research in inflammatory arthritis in the last two decades, mostly due to their ability to indicate tissue related damage after active or passive release from injured cells. From HMGB1, S100A8/A9 and S100A12 proteins, over heat-shock proteins (HSPs) and purine metabolites (e.g. uric acid, ATP) to altered matrix proteins and interleukin-33 (IL-33), a number of alarmins have been determined until now as having a role in rheumatoid arthritis, psoriatic and juvenile idiopathic arthritis, as well as spondyloarthritis and gout. Although formerly being linked to initiation and chronification of inflammatory arthritis, driving auto- and paracrine inflammatory loops, more recent research has also unraveled the alarmins’ role in the crosstalk between innate and adaptive immunity and in resolution of inflammation. Alarmins are endogenous molecules with homeostatic roles that have reached the focus of research in inflammatory arthritis in the last two decades, mostly due to their ability to indicate tissue related damage after active or passive release from injured cells. From HMGB1, S100A8/A9 and S100A12 proteins, over heat-shock proteins (HSPs) and purine metabolites (e.g. uric acid, ATP) to altered matrix proteins and interleukin-33 (IL-33), a number of alarmins have been determined until now as having a role in rheumatoid arthritis, psoriatic and juvenile idiopathic arthritis, as well as spondyloarthritis and gout. Although formerly being linked to initiation and chronification of inflammatory arthritis, driving auto- and paracrine inflammatory loops, more recent research has also unraveled the alarmins’ role in the crosstalk between innate and adaptive immunity and in resolution of inflammation. Alarmins Elsevier Pathology Elsevier Biomarkers Elsevier Arthritis Elsevier DAMPs Elsevier Miranda-García, María Auxiliadora oth Holzinger, Dirk oth Foell, Dirk oth Wittkowski, Helmut oth Enthalten in Elsevier Calendar of Events 2014 revue du rhumatisme, international edition : official publication of the French Society of Rheumatology Paris (DE-627)ELV017983630 volume:84 year:2017 number:4 pages:401-410 extent:10 https://doi.org/10.1016/j.jbspin.2016.06.010 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 35.10 Physikalische Chemie: Allgemeines VZ AR 84 2017 4 401-410 10 045F 610 |
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alarmins firing arthritis: helpful diagnostic tools and promising therapeutic targets |
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Alarmins are endogenous molecules with homeostatic roles that have reached the focus of research in inflammatory arthritis in the last two decades, mostly due to their ability to indicate tissue related damage after active or passive release from injured cells. From HMGB1, S100A8/A9 and S100A12 proteins, over heat-shock proteins (HSPs) and purine metabolites (e.g. uric acid, ATP) to altered matrix proteins and interleukin-33 (IL-33), a number of alarmins have been determined until now as having a role in rheumatoid arthritis, psoriatic and juvenile idiopathic arthritis, as well as spondyloarthritis and gout. Although formerly being linked to initiation and chronification of inflammatory arthritis, driving auto- and paracrine inflammatory loops, more recent research has also unraveled the alarmins’ role in the crosstalk between innate and adaptive immunity and in resolution of inflammation. |
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Alarmins are endogenous molecules with homeostatic roles that have reached the focus of research in inflammatory arthritis in the last two decades, mostly due to their ability to indicate tissue related damage after active or passive release from injured cells. From HMGB1, S100A8/A9 and S100A12 proteins, over heat-shock proteins (HSPs) and purine metabolites (e.g. uric acid, ATP) to altered matrix proteins and interleukin-33 (IL-33), a number of alarmins have been determined until now as having a role in rheumatoid arthritis, psoriatic and juvenile idiopathic arthritis, as well as spondyloarthritis and gout. Although formerly being linked to initiation and chronification of inflammatory arthritis, driving auto- and paracrine inflammatory loops, more recent research has also unraveled the alarmins’ role in the crosstalk between innate and adaptive immunity and in resolution of inflammation. |
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Alarmins are endogenous molecules with homeostatic roles that have reached the focus of research in inflammatory arthritis in the last two decades, mostly due to their ability to indicate tissue related damage after active or passive release from injured cells. From HMGB1, S100A8/A9 and S100A12 proteins, over heat-shock proteins (HSPs) and purine metabolites (e.g. uric acid, ATP) to altered matrix proteins and interleukin-33 (IL-33), a number of alarmins have been determined until now as having a role in rheumatoid arthritis, psoriatic and juvenile idiopathic arthritis, as well as spondyloarthritis and gout. Although formerly being linked to initiation and chronification of inflammatory arthritis, driving auto- and paracrine inflammatory loops, more recent research has also unraveled the alarmins’ role in the crosstalk between innate and adaptive immunity and in resolution of inflammation. |
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