Identification and analysis of CD133+ melanoma stem-like cells conferring resistance to taxol: An insight into the mechanisms of their resistance and response
• Cancer stem-like cells (CSCs) are responsible for tumor initiation and progression. • We characterized the molecular mechanisms of melanoma stem-like cells (MSCs) resistance to taxol. • The analysis of the resistant mechanisms is important for the development of an efficient therapy. • The combina...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
El-Khattouti, Abdelouahid [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2014 |
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| Schlagwörter: |
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| Umfang: |
11 |
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| Übergeordnetes Werk: |
Enthalten in: GW26-e0273 Relationship between thrombelastography test and routine platelet parameters in patients with acute coronary syndrome - Hao, Lijun ELSEVIER, 2015, an international journal providing a forum for original and pertinent contributions in cancer research, Amsterdam [u.a.] |
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| Übergeordnetes Werk: |
volume:343 ; year:2014 ; number:1 ; day:1 ; month:02 ; pages:123-133 ; extent:11 |
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10.1016/j.canlet.2013.09.024 |
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| 520 | |a • Cancer stem-like cells (CSCs) are responsible for tumor initiation and progression. • We characterized the molecular mechanisms of melanoma stem-like cells (MSCs) resistance to taxol. • The analysis of the resistant mechanisms is important for the development of an efficient therapy. • The combination of ERK inhibitor with taxol, or Bax gene transfer overcome MSCs resistance to taxol. • Our data suggest relevant strategy for the treatment of melanoma metastasis. | ||
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10.1016/j.canlet.2013.09.024 doi GBVA2014010000019.pica (DE-627)ELV033892210 (ELSEVIER)S0304-3835(13)00693-9 DE-627 ger DE-627 rakwb eng 570 570 DE-600 610 VZ 600 690 VZ 51.00 bkl 51.32 bkl El-Khattouti, Abdelouahid verfasserin aut Identification and analysis of CD133+ melanoma stem-like cells conferring resistance to taxol: An insight into the mechanisms of their resistance and response 2014 11 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier • Cancer stem-like cells (CSCs) are responsible for tumor initiation and progression. • We characterized the molecular mechanisms of melanoma stem-like cells (MSCs) resistance to taxol. • The analysis of the resistant mechanisms is important for the development of an efficient therapy. • The combination of ERK inhibitor with taxol, or Bax gene transfer overcome MSCs resistance to taxol. • Our data suggest relevant strategy for the treatment of melanoma metastasis. P38 Elsevier Taxol Elsevier JNK Elsevier Cancer stem cells Elsevier CD133 Elsevier Apoptosis Elsevier Selimovic, Denis oth Haïkel, Youssef oth Megahed, Mosaad oth Gomez, Christian R. oth Hassan, Mohamed oth Enthalten in Elsevier Science Hao, Lijun ELSEVIER GW26-e0273 Relationship between thrombelastography test and routine platelet parameters in patients with acute coronary syndrome 2015 an international journal providing a forum for original and pertinent contributions in cancer research Amsterdam [u.a.] (DE-627)ELV013094742 volume:343 year:2014 number:1 day:1 month:02 pages:123-133 extent:11 https://doi.org/10.1016/j.canlet.2013.09.024 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U GBV_ILN_11 GBV_ILN_40 51.00 Werkstoffkunde: Allgemeines VZ 51.32 Werkstoffmechanik VZ AR 343 2014 1 1 0201 123-133 11 045F 570 |
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GW26-e0273 Relationship between thrombelastography test and routine platelet parameters in patients with acute coronary syndrome |
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GW26-e0273 Relationship between thrombelastography test and routine platelet parameters in patients with acute coronary syndrome |
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10.1016/j.canlet.2013.09.024 |
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570 610 600 690 |
| title_sort |
identification and analysis of cd133+ melanoma stem-like cells conferring resistance to taxol: an insight into the mechanisms of their resistance and response |
| title_auth |
Identification and analysis of CD133+ melanoma stem-like cells conferring resistance to taxol: An insight into the mechanisms of their resistance and response |
| abstract |
• Cancer stem-like cells (CSCs) are responsible for tumor initiation and progression. • We characterized the molecular mechanisms of melanoma stem-like cells (MSCs) resistance to taxol. • The analysis of the resistant mechanisms is important for the development of an efficient therapy. • The combination of ERK inhibitor with taxol, or Bax gene transfer overcome MSCs resistance to taxol. • Our data suggest relevant strategy for the treatment of melanoma metastasis. |
| abstractGer |
• Cancer stem-like cells (CSCs) are responsible for tumor initiation and progression. • We characterized the molecular mechanisms of melanoma stem-like cells (MSCs) resistance to taxol. • The analysis of the resistant mechanisms is important for the development of an efficient therapy. • The combination of ERK inhibitor with taxol, or Bax gene transfer overcome MSCs resistance to taxol. • Our data suggest relevant strategy for the treatment of melanoma metastasis. |
| abstract_unstemmed |
• Cancer stem-like cells (CSCs) are responsible for tumor initiation and progression. • We characterized the molecular mechanisms of melanoma stem-like cells (MSCs) resistance to taxol. • The analysis of the resistant mechanisms is important for the development of an efficient therapy. • The combination of ERK inhibitor with taxol, or Bax gene transfer overcome MSCs resistance to taxol. • Our data suggest relevant strategy for the treatment of melanoma metastasis. |
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Identification and analysis of CD133+ melanoma stem-like cells conferring resistance to taxol: An insight into the mechanisms of their resistance and response |
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https://doi.org/10.1016/j.canlet.2013.09.024 |
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Selimovic, Denis Haïkel, Youssef Megahed, Mosaad Gomez, Christian R. Hassan, Mohamed |
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Selimovic, Denis Haïkel, Youssef Megahed, Mosaad Gomez, Christian R. Hassan, Mohamed |
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