Total gastrectomy may result in reduced drug effectiveness due to an increase in the expression of the drug-metabolizing enzyme Cytochrome P450, in the liver

Abstract In patients with gastrectomy, it is possible that drug effectiveness is reduced compared to healthy subjects due to the increased of the drug-metabolizing enzyme, Cytochrome P450 (CYP). The purpose of this study is to verify this possibility. Gastrectomy model mice were prepared to evaluate...
Ausführliche Beschreibung

Gespeichert in:
Autor*in:

Ishii, Makoto [verfasserIn]

Toda, Takahiro

Ikarashi, Nobutomo

Kusunoki, Yoshiki

Kon, Risako

Ochiai, Wataru

Machida, Yoshiaki

Sugiyama, Kiyoshi

Format:

E-Artikel

Sprache:

Englisch

Erschienen:

2014transfer abstract

Schlagwörter:

Imatinib

Cytochrome P450

Gastrectomy

Umfang:

9

Übergeordnetes Werk:

Enthalten in: The face of wrongdoing? An expectancy violations perspective on CEO facial characteristics and media coverage of misconducting firms - Heyden, Mariano L.M. ELSEVIER, 2022, official journal of the European Federation for Pharmaceutical Sciences, New York, NY [u.a.]

Übergeordnetes Werk:

volume:51 ; year:2014 ; day:23 ; month:01 ; pages:180-188 ; extent:9

Links:

Volltext

DOI / URN:

10.1016/j.ejps.2013.09.017

Katalog-ID:

ELV034032002

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