Involvement of the NO/cGMP/KATP pathway in the antinociceptive effect of the new pyrazole 5-(1-(3-fluorophenyl)-1H-pyrazol-4-yl)-2H-tetrazole (LQFM-021)

• The pyrasole compound LQFM 021 has peripheral antinociceptive effect. • The NO release is important for antinociceptive effect of the LQFM 021. • The antinociceptive effect of the LQFM 021 involved the NO/cGMP/KATP pathway.

Gespeichert in:
Autor*in:

Florentino, Iziara F. [verfasserIn]

Galdino, Pablinny M.

De Oliveira, Lanussy P.

Silva, Daiany P.B.

Pazini, Francine

Vanderlinde, Frederico A.

Lião, Luciano M.

Menegatti, Ricardo

Costa, Elson A.

Format:

E-Artikel

Sprache:

Englisch

Erschienen:

2015

Umfang:

8

Übergeordnetes Werk:

Enthalten in: Enhancement of (−)-epigallocatechin-3-gallate and theaflavin-3-3′-digallate induced apoptosis by ascorbic acid in human lung adenocarcinoma SPC-A-1 cells and esophageal carcinoma Eca-109 cells via MAPK pathways - Gao, Ying ELSEVIER, 2013, biology and chemistry : the official journal of the Nitric Oxide Society, Orlando, Fla

Übergeordnetes Werk:

volume:47 ; year:2015 ; day:1 ; month:05 ; pages:17-24 ; extent:8

Links:

Volltext

DOI / URN:

10.1016/j.niox.2015.02.146

Katalog-ID:

ELV034772219

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