RASSF4 promotes EV71 replication to accelerate the inhibition of the phosphorylation of AKT
Enterovirus 71 (EV71) is a neurotropic virus that causes hand, foot and mouth disease (HFMD), occasionally leading to death. As a member of the RAS association domain family (RASSFs), RASSF4 plays important roles in cell death, tumor development and signal transduction. However, little is known abou...
Ausführliche Beschreibung
Autor*in: |
Zhang, Fengfeng [verfasserIn] |
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E-Artikel |
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Sprache: |
Englisch |
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2015transfer abstract |
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Umfang: |
6 |
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Übergeordnetes Werk: |
Enthalten in: Preparation and characterization of glass-ceramics via co-sintering of coal fly ash and oil shale ash-derived amorphous slag - Zhang, Zhikun ELSEVIER, 2019, BBRC, Orlando, Fla |
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Übergeordnetes Werk: |
volume:458 ; year:2015 ; number:4 ; day:20 ; month:03 ; pages:810-815 ; extent:6 |
Links: |
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DOI / URN: |
10.1016/j.bbrc.2015.02.035 |
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ELV034882219 |
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520 | |a Enterovirus 71 (EV71) is a neurotropic virus that causes hand, foot and mouth disease (HFMD), occasionally leading to death. As a member of the RAS association domain family (RASSFs), RASSF4 plays important roles in cell death, tumor development and signal transduction. However, little is known about the relationship between RASSF4 and EV71. Our study reveals for the first time that RASSF4 promotes EV71 replication and then accelerates AKT phosphorylation inhibition in EV71-infected 293T cells, suggesting that RASSF4 may be a potential new target for designing therapeutic measures to prevent and control EV71 infection. | ||
520 | |a Enterovirus 71 (EV71) is a neurotropic virus that causes hand, foot and mouth disease (HFMD), occasionally leading to death. As a member of the RAS association domain family (RASSFs), RASSF4 plays important roles in cell death, tumor development and signal transduction. However, little is known about the relationship between RASSF4 and EV71. Our study reveals for the first time that RASSF4 promotes EV71 replication and then accelerates AKT phosphorylation inhibition in EV71-infected 293T cells, suggesting that RASSF4 may be a potential new target for designing therapeutic measures to prevent and control EV71 infection. | ||
650 | 7 | |a Enterovirus 71 |2 Elsevier | |
650 | 7 | |a RASSF4 |2 Elsevier | |
650 | 7 | |a Replication |2 Elsevier | |
650 | 7 | |a AKT phosphorylation |2 Elsevier | |
700 | 1 | |a Liu, Yongjuan |4 oth | |
700 | 1 | |a Chen, Xiong |4 oth | |
700 | 1 | |a Dong, Lanlan |4 oth | |
700 | 1 | |a Zhou, Bingfei |4 oth | |
700 | 1 | |a Cheng, Qingqing |4 oth | |
700 | 1 | |a Han, Song |4 oth | |
700 | 1 | |a Liu, Zhongchun |4 oth | |
700 | 1 | |a Peng, Biwen |4 oth | |
700 | 1 | |a He, Xiaohua |4 oth | |
700 | 1 | |a Liu, Wanhong |4 oth | |
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10.1016/j.bbrc.2015.02.035 doi GBVA2015020000024.pica (DE-627)ELV034882219 (ELSEVIER)S0006-291X(15)00253-3 DE-627 ger DE-627 rakwb eng 570 570 DE-600 670 VZ 51.60 bkl 58.45 bkl Zhang, Fengfeng verfasserin aut RASSF4 promotes EV71 replication to accelerate the inhibition of the phosphorylation of AKT 2015transfer abstract 6 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Enterovirus 71 (EV71) is a neurotropic virus that causes hand, foot and mouth disease (HFMD), occasionally leading to death. As a member of the RAS association domain family (RASSFs), RASSF4 plays important roles in cell death, tumor development and signal transduction. However, little is known about the relationship between RASSF4 and EV71. Our study reveals for the first time that RASSF4 promotes EV71 replication and then accelerates AKT phosphorylation inhibition in EV71-infected 293T cells, suggesting that RASSF4 may be a potential new target for designing therapeutic measures to prevent and control EV71 infection. Enterovirus 71 (EV71) is a neurotropic virus that causes hand, foot and mouth disease (HFMD), occasionally leading to death. As a member of the RAS association domain family (RASSFs), RASSF4 plays important roles in cell death, tumor development and signal transduction. However, little is known about the relationship between RASSF4 and EV71. Our study reveals for the first time that RASSF4 promotes EV71 replication and then accelerates AKT phosphorylation inhibition in EV71-infected 293T cells, suggesting that RASSF4 may be a potential new target for designing therapeutic measures to prevent and control EV71 infection. Enterovirus 71 Elsevier RASSF4 Elsevier Replication Elsevier AKT phosphorylation Elsevier Liu, Yongjuan oth Chen, Xiong oth Dong, Lanlan oth Zhou, Bingfei oth Cheng, Qingqing oth Han, Song oth Liu, Zhongchun oth Peng, Biwen oth He, Xiaohua oth Liu, Wanhong oth Enthalten in Academic Press Zhang, Zhikun ELSEVIER Preparation and characterization of glass-ceramics via co-sintering of coal fly ash and oil shale ash-derived amorphous slag 2019 BBRC Orlando, Fla (DE-627)ELV002811154 volume:458 year:2015 number:4 day:20 month:03 pages:810-815 extent:6 https://doi.org/10.1016/j.bbrc.2015.02.035 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U 51.60 Keramische Werkstoffe Hartstoffe Werkstoffkunde VZ 58.45 Gesteinshüttenkunde VZ AR 458 2015 4 20 0320 810-815 6 045F 570 |
spelling |
10.1016/j.bbrc.2015.02.035 doi GBVA2015020000024.pica (DE-627)ELV034882219 (ELSEVIER)S0006-291X(15)00253-3 DE-627 ger DE-627 rakwb eng 570 570 DE-600 670 VZ 51.60 bkl 58.45 bkl Zhang, Fengfeng verfasserin aut RASSF4 promotes EV71 replication to accelerate the inhibition of the phosphorylation of AKT 2015transfer abstract 6 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Enterovirus 71 (EV71) is a neurotropic virus that causes hand, foot and mouth disease (HFMD), occasionally leading to death. As a member of the RAS association domain family (RASSFs), RASSF4 plays important roles in cell death, tumor development and signal transduction. However, little is known about the relationship between RASSF4 and EV71. Our study reveals for the first time that RASSF4 promotes EV71 replication and then accelerates AKT phosphorylation inhibition in EV71-infected 293T cells, suggesting that RASSF4 may be a potential new target for designing therapeutic measures to prevent and control EV71 infection. Enterovirus 71 (EV71) is a neurotropic virus that causes hand, foot and mouth disease (HFMD), occasionally leading to death. As a member of the RAS association domain family (RASSFs), RASSF4 plays important roles in cell death, tumor development and signal transduction. However, little is known about the relationship between RASSF4 and EV71. Our study reveals for the first time that RASSF4 promotes EV71 replication and then accelerates AKT phosphorylation inhibition in EV71-infected 293T cells, suggesting that RASSF4 may be a potential new target for designing therapeutic measures to prevent and control EV71 infection. Enterovirus 71 Elsevier RASSF4 Elsevier Replication Elsevier AKT phosphorylation Elsevier Liu, Yongjuan oth Chen, Xiong oth Dong, Lanlan oth Zhou, Bingfei oth Cheng, Qingqing oth Han, Song oth Liu, Zhongchun oth Peng, Biwen oth He, Xiaohua oth Liu, Wanhong oth Enthalten in Academic Press Zhang, Zhikun ELSEVIER Preparation and characterization of glass-ceramics via co-sintering of coal fly ash and oil shale ash-derived amorphous slag 2019 BBRC Orlando, Fla (DE-627)ELV002811154 volume:458 year:2015 number:4 day:20 month:03 pages:810-815 extent:6 https://doi.org/10.1016/j.bbrc.2015.02.035 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U 51.60 Keramische Werkstoffe Hartstoffe Werkstoffkunde VZ 58.45 Gesteinshüttenkunde VZ AR 458 2015 4 20 0320 810-815 6 045F 570 |
allfields_unstemmed |
10.1016/j.bbrc.2015.02.035 doi GBVA2015020000024.pica (DE-627)ELV034882219 (ELSEVIER)S0006-291X(15)00253-3 DE-627 ger DE-627 rakwb eng 570 570 DE-600 670 VZ 51.60 bkl 58.45 bkl Zhang, Fengfeng verfasserin aut RASSF4 promotes EV71 replication to accelerate the inhibition of the phosphorylation of AKT 2015transfer abstract 6 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Enterovirus 71 (EV71) is a neurotropic virus that causes hand, foot and mouth disease (HFMD), occasionally leading to death. As a member of the RAS association domain family (RASSFs), RASSF4 plays important roles in cell death, tumor development and signal transduction. However, little is known about the relationship between RASSF4 and EV71. Our study reveals for the first time that RASSF4 promotes EV71 replication and then accelerates AKT phosphorylation inhibition in EV71-infected 293T cells, suggesting that RASSF4 may be a potential new target for designing therapeutic measures to prevent and control EV71 infection. Enterovirus 71 (EV71) is a neurotropic virus that causes hand, foot and mouth disease (HFMD), occasionally leading to death. As a member of the RAS association domain family (RASSFs), RASSF4 plays important roles in cell death, tumor development and signal transduction. However, little is known about the relationship between RASSF4 and EV71. Our study reveals for the first time that RASSF4 promotes EV71 replication and then accelerates AKT phosphorylation inhibition in EV71-infected 293T cells, suggesting that RASSF4 may be a potential new target for designing therapeutic measures to prevent and control EV71 infection. Enterovirus 71 Elsevier RASSF4 Elsevier Replication Elsevier AKT phosphorylation Elsevier Liu, Yongjuan oth Chen, Xiong oth Dong, Lanlan oth Zhou, Bingfei oth Cheng, Qingqing oth Han, Song oth Liu, Zhongchun oth Peng, Biwen oth He, Xiaohua oth Liu, Wanhong oth Enthalten in Academic Press Zhang, Zhikun ELSEVIER Preparation and characterization of glass-ceramics via co-sintering of coal fly ash and oil shale ash-derived amorphous slag 2019 BBRC Orlando, Fla (DE-627)ELV002811154 volume:458 year:2015 number:4 day:20 month:03 pages:810-815 extent:6 https://doi.org/10.1016/j.bbrc.2015.02.035 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U 51.60 Keramische Werkstoffe Hartstoffe Werkstoffkunde VZ 58.45 Gesteinshüttenkunde VZ AR 458 2015 4 20 0320 810-815 6 045F 570 |
allfieldsGer |
10.1016/j.bbrc.2015.02.035 doi GBVA2015020000024.pica (DE-627)ELV034882219 (ELSEVIER)S0006-291X(15)00253-3 DE-627 ger DE-627 rakwb eng 570 570 DE-600 670 VZ 51.60 bkl 58.45 bkl Zhang, Fengfeng verfasserin aut RASSF4 promotes EV71 replication to accelerate the inhibition of the phosphorylation of AKT 2015transfer abstract 6 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Enterovirus 71 (EV71) is a neurotropic virus that causes hand, foot and mouth disease (HFMD), occasionally leading to death. As a member of the RAS association domain family (RASSFs), RASSF4 plays important roles in cell death, tumor development and signal transduction. However, little is known about the relationship between RASSF4 and EV71. Our study reveals for the first time that RASSF4 promotes EV71 replication and then accelerates AKT phosphorylation inhibition in EV71-infected 293T cells, suggesting that RASSF4 may be a potential new target for designing therapeutic measures to prevent and control EV71 infection. Enterovirus 71 (EV71) is a neurotropic virus that causes hand, foot and mouth disease (HFMD), occasionally leading to death. As a member of the RAS association domain family (RASSFs), RASSF4 plays important roles in cell death, tumor development and signal transduction. However, little is known about the relationship between RASSF4 and EV71. Our study reveals for the first time that RASSF4 promotes EV71 replication and then accelerates AKT phosphorylation inhibition in EV71-infected 293T cells, suggesting that RASSF4 may be a potential new target for designing therapeutic measures to prevent and control EV71 infection. Enterovirus 71 Elsevier RASSF4 Elsevier Replication Elsevier AKT phosphorylation Elsevier Liu, Yongjuan oth Chen, Xiong oth Dong, Lanlan oth Zhou, Bingfei oth Cheng, Qingqing oth Han, Song oth Liu, Zhongchun oth Peng, Biwen oth He, Xiaohua oth Liu, Wanhong oth Enthalten in Academic Press Zhang, Zhikun ELSEVIER Preparation and characterization of glass-ceramics via co-sintering of coal fly ash and oil shale ash-derived amorphous slag 2019 BBRC Orlando, Fla (DE-627)ELV002811154 volume:458 year:2015 number:4 day:20 month:03 pages:810-815 extent:6 https://doi.org/10.1016/j.bbrc.2015.02.035 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U 51.60 Keramische Werkstoffe Hartstoffe Werkstoffkunde VZ 58.45 Gesteinshüttenkunde VZ AR 458 2015 4 20 0320 810-815 6 045F 570 |
allfieldsSound |
10.1016/j.bbrc.2015.02.035 doi GBVA2015020000024.pica (DE-627)ELV034882219 (ELSEVIER)S0006-291X(15)00253-3 DE-627 ger DE-627 rakwb eng 570 570 DE-600 670 VZ 51.60 bkl 58.45 bkl Zhang, Fengfeng verfasserin aut RASSF4 promotes EV71 replication to accelerate the inhibition of the phosphorylation of AKT 2015transfer abstract 6 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Enterovirus 71 (EV71) is a neurotropic virus that causes hand, foot and mouth disease (HFMD), occasionally leading to death. As a member of the RAS association domain family (RASSFs), RASSF4 plays important roles in cell death, tumor development and signal transduction. However, little is known about the relationship between RASSF4 and EV71. Our study reveals for the first time that RASSF4 promotes EV71 replication and then accelerates AKT phosphorylation inhibition in EV71-infected 293T cells, suggesting that RASSF4 may be a potential new target for designing therapeutic measures to prevent and control EV71 infection. Enterovirus 71 (EV71) is a neurotropic virus that causes hand, foot and mouth disease (HFMD), occasionally leading to death. As a member of the RAS association domain family (RASSFs), RASSF4 plays important roles in cell death, tumor development and signal transduction. However, little is known about the relationship between RASSF4 and EV71. Our study reveals for the first time that RASSF4 promotes EV71 replication and then accelerates AKT phosphorylation inhibition in EV71-infected 293T cells, suggesting that RASSF4 may be a potential new target for designing therapeutic measures to prevent and control EV71 infection. Enterovirus 71 Elsevier RASSF4 Elsevier Replication Elsevier AKT phosphorylation Elsevier Liu, Yongjuan oth Chen, Xiong oth Dong, Lanlan oth Zhou, Bingfei oth Cheng, Qingqing oth Han, Song oth Liu, Zhongchun oth Peng, Biwen oth He, Xiaohua oth Liu, Wanhong oth Enthalten in Academic Press Zhang, Zhikun ELSEVIER Preparation and characterization of glass-ceramics via co-sintering of coal fly ash and oil shale ash-derived amorphous slag 2019 BBRC Orlando, Fla (DE-627)ELV002811154 volume:458 year:2015 number:4 day:20 month:03 pages:810-815 extent:6 https://doi.org/10.1016/j.bbrc.2015.02.035 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U 51.60 Keramische Werkstoffe Hartstoffe Werkstoffkunde VZ 58.45 Gesteinshüttenkunde VZ AR 458 2015 4 20 0320 810-815 6 045F 570 |
language |
English |
source |
Enthalten in Preparation and characterization of glass-ceramics via co-sintering of coal fly ash and oil shale ash-derived amorphous slag Orlando, Fla volume:458 year:2015 number:4 day:20 month:03 pages:810-815 extent:6 |
sourceStr |
Enthalten in Preparation and characterization of glass-ceramics via co-sintering of coal fly ash and oil shale ash-derived amorphous slag Orlando, Fla volume:458 year:2015 number:4 day:20 month:03 pages:810-815 extent:6 |
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Enterovirus 71 RASSF4 Replication AKT phosphorylation |
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Preparation and characterization of glass-ceramics via co-sintering of coal fly ash and oil shale ash-derived amorphous slag |
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Zhang, Fengfeng @@aut@@ Liu, Yongjuan @@oth@@ Chen, Xiong @@oth@@ Dong, Lanlan @@oth@@ Zhou, Bingfei @@oth@@ Cheng, Qingqing @@oth@@ Han, Song @@oth@@ Liu, Zhongchun @@oth@@ Peng, Biwen @@oth@@ He, Xiaohua @@oth@@ Liu, Wanhong @@oth@@ |
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rassf4 promotes ev71 replication to accelerate the inhibition of the phosphorylation of akt |
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RASSF4 promotes EV71 replication to accelerate the inhibition of the phosphorylation of AKT |
abstract |
Enterovirus 71 (EV71) is a neurotropic virus that causes hand, foot and mouth disease (HFMD), occasionally leading to death. As a member of the RAS association domain family (RASSFs), RASSF4 plays important roles in cell death, tumor development and signal transduction. However, little is known about the relationship between RASSF4 and EV71. Our study reveals for the first time that RASSF4 promotes EV71 replication and then accelerates AKT phosphorylation inhibition in EV71-infected 293T cells, suggesting that RASSF4 may be a potential new target for designing therapeutic measures to prevent and control EV71 infection. |
abstractGer |
Enterovirus 71 (EV71) is a neurotropic virus that causes hand, foot and mouth disease (HFMD), occasionally leading to death. As a member of the RAS association domain family (RASSFs), RASSF4 plays important roles in cell death, tumor development and signal transduction. However, little is known about the relationship between RASSF4 and EV71. Our study reveals for the first time that RASSF4 promotes EV71 replication and then accelerates AKT phosphorylation inhibition in EV71-infected 293T cells, suggesting that RASSF4 may be a potential new target for designing therapeutic measures to prevent and control EV71 infection. |
abstract_unstemmed |
Enterovirus 71 (EV71) is a neurotropic virus that causes hand, foot and mouth disease (HFMD), occasionally leading to death. As a member of the RAS association domain family (RASSFs), RASSF4 plays important roles in cell death, tumor development and signal transduction. However, little is known about the relationship between RASSF4 and EV71. Our study reveals for the first time that RASSF4 promotes EV71 replication and then accelerates AKT phosphorylation inhibition in EV71-infected 293T cells, suggesting that RASSF4 may be a potential new target for designing therapeutic measures to prevent and control EV71 infection. |
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RASSF4 promotes EV71 replication to accelerate the inhibition of the phosphorylation of AKT |
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Liu, Yongjuan Chen, Xiong Dong, Lanlan Zhou, Bingfei Cheng, Qingqing Han, Song Liu, Zhongchun Peng, Biwen He, Xiaohua Liu, Wanhong |
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