Blockade of thymic stromal lymphopoietin (TSLP) receptor inhibits TSLP-driven proliferation and signalling in lymphoblasts from a subset of B-precursor ALL patients
• Lymphoblasts from roughly 20% of B cell precursor ALL patients express the TSLP receptor. • TSLP triggers proliferation and JAK/STAT-mediated gene regulation in TSLPR+ BCP-ALL cells. • TSLPR inhibition represses proliferation and STAT activity in TSLPR+ BCP-ALL cells. • Blockade of the TSLPR is a...
Ausführliche Beschreibung
Autor*in: |
Vetter, Tina [verfasserIn] |
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Format: |
E-Artikel |
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Sprache: |
Englisch |
Erschienen: |
2016 |
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Schlagwörter: |
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Umfang: |
6 |
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Übergeordnetes Werk: |
Enthalten in: N - Li, Danyang ELSEVIER, 2019, clinical and laboratory studies, Amsterdam [u.a.] |
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Übergeordnetes Werk: |
volume:40 ; year:2016 ; pages:38-43 ; extent:6 |
Links: |
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DOI / URN: |
10.1016/j.leukres.2015.10.003 |
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Katalog-ID: |
ELV035047550 |
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10.1016/j.leukres.2015.10.003 doi GBVA2016003000009.pica (DE-627)ELV035047550 (ELSEVIER)S0145-2126(15)30395-7 DE-627 ger DE-627 rakwb eng 610 610 DE-600 333.7 610 VZ 43.12 bkl 43.13 bkl 44.13 bkl Vetter, Tina verfasserin aut Blockade of thymic stromal lymphopoietin (TSLP) receptor inhibits TSLP-driven proliferation and signalling in lymphoblasts from a subset of B-precursor ALL patients 2016 6 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier • Lymphoblasts from roughly 20% of B cell precursor ALL patients express the TSLP receptor. • TSLP triggers proliferation and JAK/STAT-mediated gene regulation in TSLPR+ BCP-ALL cells. • TSLPR inhibition represses proliferation and STAT activity in TSLPR+ BCP-ALL cells. • Blockade of the TSLPR is a potential therapeutic option for a subset of BCP-ALL patients. TSLP Elsevier Cytokine receptors Elsevier B-precursor ALL Elsevier Inhibitory antibody Elsevier Borowski, Andreas oth Wohlmann, Andreas oth Ranjan, Nilabh oth Kuepper, Michael oth Badura, Susanne oth Ottmann, Oliver G. oth Friedrich, Karlheinz oth Enthalten in Elsevier Science Li, Danyang ELSEVIER N 2019 clinical and laboratory studies Amsterdam [u.a.] (DE-627)ELV002185202 volume:40 year:2016 pages:38-43 extent:6 https://doi.org/10.1016/j.leukres.2015.10.003 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA SSG-OPC-GGO 43.12 Umweltchemie VZ 43.13 Umwelttoxikologie VZ 44.13 Medizinische Ökologie VZ AR 40 2016 38-43 6 045F 610 |
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10.1016/j.leukres.2015.10.003 doi GBVA2016003000009.pica (DE-627)ELV035047550 (ELSEVIER)S0145-2126(15)30395-7 DE-627 ger DE-627 rakwb eng 610 610 DE-600 333.7 610 VZ 43.12 bkl 43.13 bkl 44.13 bkl Vetter, Tina verfasserin aut Blockade of thymic stromal lymphopoietin (TSLP) receptor inhibits TSLP-driven proliferation and signalling in lymphoblasts from a subset of B-precursor ALL patients 2016 6 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier • Lymphoblasts from roughly 20% of B cell precursor ALL patients express the TSLP receptor. • TSLP triggers proliferation and JAK/STAT-mediated gene regulation in TSLPR+ BCP-ALL cells. • TSLPR inhibition represses proliferation and STAT activity in TSLPR+ BCP-ALL cells. • Blockade of the TSLPR is a potential therapeutic option for a subset of BCP-ALL patients. TSLP Elsevier Cytokine receptors Elsevier B-precursor ALL Elsevier Inhibitory antibody Elsevier Borowski, Andreas oth Wohlmann, Andreas oth Ranjan, Nilabh oth Kuepper, Michael oth Badura, Susanne oth Ottmann, Oliver G. oth Friedrich, Karlheinz oth Enthalten in Elsevier Science Li, Danyang ELSEVIER N 2019 clinical and laboratory studies Amsterdam [u.a.] (DE-627)ELV002185202 volume:40 year:2016 pages:38-43 extent:6 https://doi.org/10.1016/j.leukres.2015.10.003 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA SSG-OPC-GGO 43.12 Umweltchemie VZ 43.13 Umwelttoxikologie VZ 44.13 Medizinische Ökologie VZ AR 40 2016 38-43 6 045F 610 |
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10.1016/j.leukres.2015.10.003 doi GBVA2016003000009.pica (DE-627)ELV035047550 (ELSEVIER)S0145-2126(15)30395-7 DE-627 ger DE-627 rakwb eng 610 610 DE-600 333.7 610 VZ 43.12 bkl 43.13 bkl 44.13 bkl Vetter, Tina verfasserin aut Blockade of thymic stromal lymphopoietin (TSLP) receptor inhibits TSLP-driven proliferation and signalling in lymphoblasts from a subset of B-precursor ALL patients 2016 6 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier • Lymphoblasts from roughly 20% of B cell precursor ALL patients express the TSLP receptor. • TSLP triggers proliferation and JAK/STAT-mediated gene regulation in TSLPR+ BCP-ALL cells. • TSLPR inhibition represses proliferation and STAT activity in TSLPR+ BCP-ALL cells. • Blockade of the TSLPR is a potential therapeutic option for a subset of BCP-ALL patients. TSLP Elsevier Cytokine receptors Elsevier B-precursor ALL Elsevier Inhibitory antibody Elsevier Borowski, Andreas oth Wohlmann, Andreas oth Ranjan, Nilabh oth Kuepper, Michael oth Badura, Susanne oth Ottmann, Oliver G. oth Friedrich, Karlheinz oth Enthalten in Elsevier Science Li, Danyang ELSEVIER N 2019 clinical and laboratory studies Amsterdam [u.a.] (DE-627)ELV002185202 volume:40 year:2016 pages:38-43 extent:6 https://doi.org/10.1016/j.leukres.2015.10.003 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA SSG-OPC-GGO 43.12 Umweltchemie VZ 43.13 Umwelttoxikologie VZ 44.13 Medizinische Ökologie VZ AR 40 2016 38-43 6 045F 610 |
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10.1016/j.leukres.2015.10.003 doi GBVA2016003000009.pica (DE-627)ELV035047550 (ELSEVIER)S0145-2126(15)30395-7 DE-627 ger DE-627 rakwb eng 610 610 DE-600 333.7 610 VZ 43.12 bkl 43.13 bkl 44.13 bkl Vetter, Tina verfasserin aut Blockade of thymic stromal lymphopoietin (TSLP) receptor inhibits TSLP-driven proliferation and signalling in lymphoblasts from a subset of B-precursor ALL patients 2016 6 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier • Lymphoblasts from roughly 20% of B cell precursor ALL patients express the TSLP receptor. • TSLP triggers proliferation and JAK/STAT-mediated gene regulation in TSLPR+ BCP-ALL cells. • TSLPR inhibition represses proliferation and STAT activity in TSLPR+ BCP-ALL cells. • Blockade of the TSLPR is a potential therapeutic option for a subset of BCP-ALL patients. TSLP Elsevier Cytokine receptors Elsevier B-precursor ALL Elsevier Inhibitory antibody Elsevier Borowski, Andreas oth Wohlmann, Andreas oth Ranjan, Nilabh oth Kuepper, Michael oth Badura, Susanne oth Ottmann, Oliver G. oth Friedrich, Karlheinz oth Enthalten in Elsevier Science Li, Danyang ELSEVIER N 2019 clinical and laboratory studies Amsterdam [u.a.] (DE-627)ELV002185202 volume:40 year:2016 pages:38-43 extent:6 https://doi.org/10.1016/j.leukres.2015.10.003 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA SSG-OPC-GGO 43.12 Umweltchemie VZ 43.13 Umwelttoxikologie VZ 44.13 Medizinische Ökologie VZ AR 40 2016 38-43 6 045F 610 |
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10.1016/j.leukres.2015.10.003 doi GBVA2016003000009.pica (DE-627)ELV035047550 (ELSEVIER)S0145-2126(15)30395-7 DE-627 ger DE-627 rakwb eng 610 610 DE-600 333.7 610 VZ 43.12 bkl 43.13 bkl 44.13 bkl Vetter, Tina verfasserin aut Blockade of thymic stromal lymphopoietin (TSLP) receptor inhibits TSLP-driven proliferation and signalling in lymphoblasts from a subset of B-precursor ALL patients 2016 6 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier • Lymphoblasts from roughly 20% of B cell precursor ALL patients express the TSLP receptor. • TSLP triggers proliferation and JAK/STAT-mediated gene regulation in TSLPR+ BCP-ALL cells. • TSLPR inhibition represses proliferation and STAT activity in TSLPR+ BCP-ALL cells. • Blockade of the TSLPR is a potential therapeutic option for a subset of BCP-ALL patients. TSLP Elsevier Cytokine receptors Elsevier B-precursor ALL Elsevier Inhibitory antibody Elsevier Borowski, Andreas oth Wohlmann, Andreas oth Ranjan, Nilabh oth Kuepper, Michael oth Badura, Susanne oth Ottmann, Oliver G. oth Friedrich, Karlheinz oth Enthalten in Elsevier Science Li, Danyang ELSEVIER N 2019 clinical and laboratory studies Amsterdam [u.a.] (DE-627)ELV002185202 volume:40 year:2016 pages:38-43 extent:6 https://doi.org/10.1016/j.leukres.2015.10.003 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA SSG-OPC-GGO 43.12 Umweltchemie VZ 43.13 Umwelttoxikologie VZ 44.13 Medizinische Ökologie VZ AR 40 2016 38-43 6 045F 610 |
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blockade of thymic stromal lymphopoietin (tslp) receptor inhibits tslp-driven proliferation and signalling in lymphoblasts from a subset of b-precursor all patients |
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Blockade of thymic stromal lymphopoietin (TSLP) receptor inhibits TSLP-driven proliferation and signalling in lymphoblasts from a subset of B-precursor ALL patients |
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• Lymphoblasts from roughly 20% of B cell precursor ALL patients express the TSLP receptor. • TSLP triggers proliferation and JAK/STAT-mediated gene regulation in TSLPR+ BCP-ALL cells. • TSLPR inhibition represses proliferation and STAT activity in TSLPR+ BCP-ALL cells. • Blockade of the TSLPR is a potential therapeutic option for a subset of BCP-ALL patients. |
abstractGer |
• Lymphoblasts from roughly 20% of B cell precursor ALL patients express the TSLP receptor. • TSLP triggers proliferation and JAK/STAT-mediated gene regulation in TSLPR+ BCP-ALL cells. • TSLPR inhibition represses proliferation and STAT activity in TSLPR+ BCP-ALL cells. • Blockade of the TSLPR is a potential therapeutic option for a subset of BCP-ALL patients. |
abstract_unstemmed |
• Lymphoblasts from roughly 20% of B cell precursor ALL patients express the TSLP receptor. • TSLP triggers proliferation and JAK/STAT-mediated gene regulation in TSLPR+ BCP-ALL cells. • TSLPR inhibition represses proliferation and STAT activity in TSLPR+ BCP-ALL cells. • Blockade of the TSLPR is a potential therapeutic option for a subset of BCP-ALL patients. |
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title_short |
Blockade of thymic stromal lymphopoietin (TSLP) receptor inhibits TSLP-driven proliferation and signalling in lymphoblasts from a subset of B-precursor ALL patients |
url |
https://doi.org/10.1016/j.leukres.2015.10.003 |
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author2 |
Borowski, Andreas Wohlmann, Andreas Ranjan, Nilabh Kuepper, Michael Badura, Susanne Ottmann, Oliver G. Friedrich, Karlheinz |
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Borowski, Andreas Wohlmann, Andreas Ranjan, Nilabh Kuepper, Michael Badura, Susanne Ottmann, Oliver G. Friedrich, Karlheinz |
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doi_str |
10.1016/j.leukres.2015.10.003 |
up_date |
2024-07-06T22:40:03.105Z |
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1803871168083525632 |
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