Receptor for advanced glycation end products (RAGE) knockout reduces fetal dysmorphogenesis in murine diabetic pregnancy
• Pregnant RAGE−/− mice produce offspring, which are indistinguishable from WT offspring. • Diabetes in pregnant WT mice yields fetal congenital malformations. • Diabetes in pregnant RAGE−/− mice yields fewer congenital malformations than WT mice. • Fetuses of diabetic RAGE−/− mice have lower NF-κB...
Ausführliche Beschreibung
Autor*in: |
Ejdesjö, Andreas [verfasserIn] |
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Format: |
E-Artikel |
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Sprache: |
Englisch |
Erschienen: |
2016 |
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Schlagwörter: |
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Umfang: |
9 |
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Übergeordnetes Werk: |
Enthalten in: Porous silicon Bragg mirrors on single- and multi-crystalline silicon for solar cells - 2013transfer abstract, Amsterdam [u.a.] |
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Übergeordnetes Werk: |
volume:62 ; year:2016 ; pages:62-70 ; extent:9 |
Links: |
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DOI / URN: |
10.1016/j.reprotox.2016.04.015 |
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Katalog-ID: |
ELV035390972 |
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10.1016/j.reprotox.2016.04.015 doi GBVA2016015000004.pica (DE-627)ELV035390972 (ELSEVIER)S0890-6238(16)30065-X DE-627 ger DE-627 rakwb eng 610 610 DE-600 530 VZ 620 VZ Ejdesjö, Andreas verfasserin aut Receptor for advanced glycation end products (RAGE) knockout reduces fetal dysmorphogenesis in murine diabetic pregnancy 2016 9 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier • Pregnant RAGE−/− mice produce offspring, which are indistinguishable from WT offspring. • Diabetes in pregnant WT mice yields fetal congenital malformations. • Diabetes in pregnant RAGE−/− mice yields fewer congenital malformations than WT mice. • Fetuses of diabetic RAGE−/− mice have lower NF-κB activation and isoprostane levels than WT. • RAGE activation is involved in the teratogenicity of diabetic pregnancy. CML Elsevier NFκB Elsevier PKC Elsevier DAG Elsevier HMGB1 Elsevier RAGE Elsevier N Elsevier BSA Elsevier 3 Elsevier MD Elsevier ROS Elsevier STZ Elsevier GAPDH Elsevier GD Elsevier WT Elsevier AGE Elsevier Brings, Sebastian oth Fleming, Thomas oth Fred, Rikard G. oth Nawroth, Peter P. oth Eriksson, Ulf J. oth Enthalten in Elsevier Science Porous silicon Bragg mirrors on single- and multi-crystalline silicon for solar cells 2013transfer abstract Amsterdam [u.a.] (DE-627)ELV022089438 volume:62 year:2016 pages:62-70 extent:9 https://doi.org/10.1016/j.reprotox.2016.04.015 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U GBV_ILN_22 GBV_ILN_24 GBV_ILN_26 GBV_ILN_31 GBV_ILN_40 AR 62 2016 62-70 9 045F 610 |
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10.1016/j.reprotox.2016.04.015 doi GBVA2016015000004.pica (DE-627)ELV035390972 (ELSEVIER)S0890-6238(16)30065-X DE-627 ger DE-627 rakwb eng 610 610 DE-600 530 VZ 620 VZ Ejdesjö, Andreas verfasserin aut Receptor for advanced glycation end products (RAGE) knockout reduces fetal dysmorphogenesis in murine diabetic pregnancy 2016 9 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier • Pregnant RAGE−/− mice produce offspring, which are indistinguishable from WT offspring. • Diabetes in pregnant WT mice yields fetal congenital malformations. • Diabetes in pregnant RAGE−/− mice yields fewer congenital malformations than WT mice. • Fetuses of diabetic RAGE−/− mice have lower NF-κB activation and isoprostane levels than WT. • RAGE activation is involved in the teratogenicity of diabetic pregnancy. CML Elsevier NFκB Elsevier PKC Elsevier DAG Elsevier HMGB1 Elsevier RAGE Elsevier N Elsevier BSA Elsevier 3 Elsevier MD Elsevier ROS Elsevier STZ Elsevier GAPDH Elsevier GD Elsevier WT Elsevier AGE Elsevier Brings, Sebastian oth Fleming, Thomas oth Fred, Rikard G. oth Nawroth, Peter P. oth Eriksson, Ulf J. oth Enthalten in Elsevier Science Porous silicon Bragg mirrors on single- and multi-crystalline silicon for solar cells 2013transfer abstract Amsterdam [u.a.] (DE-627)ELV022089438 volume:62 year:2016 pages:62-70 extent:9 https://doi.org/10.1016/j.reprotox.2016.04.015 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U GBV_ILN_22 GBV_ILN_24 GBV_ILN_26 GBV_ILN_31 GBV_ILN_40 AR 62 2016 62-70 9 045F 610 |
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dewey-full |
610 530 620 |
title_sort |
receptor for advanced glycation end products (rage) knockout reduces fetal dysmorphogenesis in murine diabetic pregnancy |
title_auth |
Receptor for advanced glycation end products (RAGE) knockout reduces fetal dysmorphogenesis in murine diabetic pregnancy |
abstract |
• Pregnant RAGE−/− mice produce offspring, which are indistinguishable from WT offspring. • Diabetes in pregnant WT mice yields fetal congenital malformations. • Diabetes in pregnant RAGE−/− mice yields fewer congenital malformations than WT mice. • Fetuses of diabetic RAGE−/− mice have lower NF-κB activation and isoprostane levels than WT. • RAGE activation is involved in the teratogenicity of diabetic pregnancy. |
abstractGer |
• Pregnant RAGE−/− mice produce offspring, which are indistinguishable from WT offspring. • Diabetes in pregnant WT mice yields fetal congenital malformations. • Diabetes in pregnant RAGE−/− mice yields fewer congenital malformations than WT mice. • Fetuses of diabetic RAGE−/− mice have lower NF-κB activation and isoprostane levels than WT. • RAGE activation is involved in the teratogenicity of diabetic pregnancy. |
abstract_unstemmed |
• Pregnant RAGE−/− mice produce offspring, which are indistinguishable from WT offspring. • Diabetes in pregnant WT mice yields fetal congenital malformations. • Diabetes in pregnant RAGE−/− mice yields fewer congenital malformations than WT mice. • Fetuses of diabetic RAGE−/− mice have lower NF-κB activation and isoprostane levels than WT. • RAGE activation is involved in the teratogenicity of diabetic pregnancy. |
collection_details |
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title_short |
Receptor for advanced glycation end products (RAGE) knockout reduces fetal dysmorphogenesis in murine diabetic pregnancy |
url |
https://doi.org/10.1016/j.reprotox.2016.04.015 |
remote_bool |
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author2 |
Brings, Sebastian Fleming, Thomas Fred, Rikard G. Nawroth, Peter P. Eriksson, Ulf J. |
author2Str |
Brings, Sebastian Fleming, Thomas Fred, Rikard G. Nawroth, Peter P. Eriksson, Ulf J. |
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doi_str |
10.1016/j.reprotox.2016.04.015 |
up_date |
2024-07-06T17:26:15.974Z |
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