One pot synthesis of α,β-epoxy ketones by oxidative coupling of methyl arenes with cinnamic acids involving C(sp3)―H activation and decarboxylative strategy

A new one pot oxidative coupling of methyl arenes with cinnamic acids has been developed for the synthesis of α,β-epoxy ketones using MnO2/TBHP combination. The process involves a co-existing C(sp3)―H activation and decarboxylation under aqueous medium, which makes it practical and attractive.

Gespeichert in:
Autor*in:

Singh, Rahul [verfasserIn]

Kumar, Saurabh

Singh, Krishna Nand

Format:

E-Artikel

Sprache:

Englisch

Erschienen:

2017

Schlagwörter:

CH activation

Decarboxylation

Epoxidation

Carboxylic acids

Oxidative coupling

Umfang:

5

Übergeordnetes Werk:

Enthalten in: Therapeutic Advances in Pediatric Multiple Sclerosis - 2013, the international journal for the rapid publication of full original research papers and critical reviews in organic chemistry, Amsterdam [u.a.]

Übergeordnetes Werk:

volume:73 ; year:2017 ; number:21 ; day:25 ; month:05 ; pages:3074-3078 ; extent:5

Links:

Volltext

DOI / URN:

10.1016/j.tet.2017.04.025

Katalog-ID:

ELV035653892

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