miR-1247 blocks SOX9–mediated regeneration in alcohol- and fibrosis-associated acute kidney injury in mice

• Alcohol and fibrosis-associated acute kidney injury is characterized by loss of the SOX9 protein. • The up-regulated microRNA miR-1247 targets the Sox9 mRNA. • The over-expression of miR-1247 is mediated by the elevation of histone H3 lysine 4 trimethylation.

Gespeichert in:

Autor*in:	Dreval, Kostiantyn [verfasserIn] de Conti, Aline Furuya, Shinji Beland, Frederick A. Rusyn, Ivan Pogribny, Igor P.

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2017

Schlagwörter:	H3K56ac H3K9me3 HRP EtOH ChIP ACTB H4K16ac Ngal Havcr H3K9ac ANOVA miRNA Sox9 CpG AKI MeDIP PBS NBT SSC DIG CCl4 Lcn2 H3K4me3 H3K27ac GAPDH AP Dnmt H4K20me3 BCIP Kim1 H3K27me3

Umfang:	10

Übergeordnetes Werk:	Enthalten in: Too late or too little? Potential for Alzheimer's disease passive immunotherapy via targeted intracerebroventricular delivery - 2013, an international journal concerned with the effects of chemicals on living systems and immunotoxicology, Amsterdam [u.a.]
Übergeordnetes Werk:	volume:384 ; year:2017 ; day:1 ; month:06 ; pages:40-49 ; extent:10

Links:	Volltext

DOI / URN:	10.1016/j.tox.2017.03.004

Katalog-ID:	ELV035858389

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matchkey_str	drevalkostiantyndecontialinefuruyashinji:2017----:i14boksxmdaergnrtoiachlnfboiascae
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allfields	10.1016/j.tox.2017.03.004 doi GBVA2017009000026.pica (DE-627)ELV035858389 (ELSEVIER)S0300-483X(17)30074-4 DE-627 ger DE-627 rakwb eng 570 540 610 570 DE-600 540 DE-600 610 DE-600 610 VZ 530 VZ 52.56 bkl Dreval, Kostiantyn verfasserin aut miR-1247 blocks SOX9–mediated regeneration in alcohol- and fibrosis-associated acute kidney injury in mice 2017 10 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier • Alcohol and fibrosis-associated acute kidney injury is characterized by loss of the SOX9 protein. • The up-regulated microRNA miR-1247 targets the Sox9 mRNA. • The over-expression of miR-1247 is mediated by the elevation of histone H3 lysine 4 trimethylation. H3K56ac Elsevier H3K9me3 Elsevier HRP Elsevier EtOH Elsevier ChIP Elsevier ACTB Elsevier H4K16ac Elsevier Ngal Elsevier Havcr Elsevier H3K9ac Elsevier ANOVA Elsevier miRNA Elsevier Sox9 Elsevier CpG Elsevier AKI Elsevier MeDIP Elsevier PBS Elsevier NBT Elsevier SSC Elsevier DIG Elsevier CCl4 Elsevier Lcn2 Elsevier H3K4me3 Elsevier H3K27ac Elsevier GAPDH Elsevier AP Elsevier Dnmt Elsevier H4K20me3 Elsevier BCIP Elsevier Kim1 Elsevier H3K27me3 Elsevier de Conti, Aline oth Furuya, Shinji oth Beland, Frederick A. oth Rusyn, Ivan oth Pogribny, Igor P. oth Enthalten in Elsevier Science Too late or too little? Potential for Alzheimer's disease passive immunotherapy via targeted intracerebroventricular delivery 2013 an international journal concerned with the effects of chemicals on living systems and immunotoxicology Amsterdam [u.a.] (DE-627)ELV011413085 volume:384 year:2017 day:1 month:06 pages:40-49 extent:10 https://doi.org/10.1016/j.tox.2017.03.004 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U GBV_ILN_22 GBV_ILN_40 GBV_ILN_105 52.56 Regenerative Energieformen alternative Energieformen VZ AR 384 2017 1 0601 40-49 10 045F 570
spelling	10.1016/j.tox.2017.03.004 doi GBVA2017009000026.pica (DE-627)ELV035858389 (ELSEVIER)S0300-483X(17)30074-4 DE-627 ger DE-627 rakwb eng 570 540 610 570 DE-600 540 DE-600 610 DE-600 610 VZ 530 VZ 52.56 bkl Dreval, Kostiantyn verfasserin aut miR-1247 blocks SOX9–mediated regeneration in alcohol- and fibrosis-associated acute kidney injury in mice 2017 10 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier • Alcohol and fibrosis-associated acute kidney injury is characterized by loss of the SOX9 protein. • The up-regulated microRNA miR-1247 targets the Sox9 mRNA. • The over-expression of miR-1247 is mediated by the elevation of histone H3 lysine 4 trimethylation. H3K56ac Elsevier H3K9me3 Elsevier HRP Elsevier EtOH Elsevier ChIP Elsevier ACTB Elsevier H4K16ac Elsevier Ngal Elsevier Havcr Elsevier H3K9ac Elsevier ANOVA Elsevier miRNA Elsevier Sox9 Elsevier CpG Elsevier AKI Elsevier MeDIP Elsevier PBS Elsevier NBT Elsevier SSC Elsevier DIG Elsevier CCl4 Elsevier Lcn2 Elsevier H3K4me3 Elsevier H3K27ac Elsevier GAPDH Elsevier AP Elsevier Dnmt Elsevier H4K20me3 Elsevier BCIP Elsevier Kim1 Elsevier H3K27me3 Elsevier de Conti, Aline oth Furuya, Shinji oth Beland, Frederick A. oth Rusyn, Ivan oth Pogribny, Igor P. oth Enthalten in Elsevier Science Too late or too little? Potential for Alzheimer's disease passive immunotherapy via targeted intracerebroventricular delivery 2013 an international journal concerned with the effects of chemicals on living systems and immunotoxicology Amsterdam [u.a.] (DE-627)ELV011413085 volume:384 year:2017 day:1 month:06 pages:40-49 extent:10 https://doi.org/10.1016/j.tox.2017.03.004 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U GBV_ILN_22 GBV_ILN_40 GBV_ILN_105 52.56 Regenerative Energieformen alternative Energieformen VZ AR 384 2017 1 0601 40-49 10 045F 570
allfields_unstemmed	10.1016/j.tox.2017.03.004 doi GBVA2017009000026.pica (DE-627)ELV035858389 (ELSEVIER)S0300-483X(17)30074-4 DE-627 ger DE-627 rakwb eng 570 540 610 570 DE-600 540 DE-600 610 DE-600 610 VZ 530 VZ 52.56 bkl Dreval, Kostiantyn verfasserin aut miR-1247 blocks SOX9–mediated regeneration in alcohol- and fibrosis-associated acute kidney injury in mice 2017 10 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier • Alcohol and fibrosis-associated acute kidney injury is characterized by loss of the SOX9 protein. • The up-regulated microRNA miR-1247 targets the Sox9 mRNA. • The over-expression of miR-1247 is mediated by the elevation of histone H3 lysine 4 trimethylation. H3K56ac Elsevier H3K9me3 Elsevier HRP Elsevier EtOH Elsevier ChIP Elsevier ACTB Elsevier H4K16ac Elsevier Ngal Elsevier Havcr Elsevier H3K9ac Elsevier ANOVA Elsevier miRNA Elsevier Sox9 Elsevier CpG Elsevier AKI Elsevier MeDIP Elsevier PBS Elsevier NBT Elsevier SSC Elsevier DIG Elsevier CCl4 Elsevier Lcn2 Elsevier H3K4me3 Elsevier H3K27ac Elsevier GAPDH Elsevier AP Elsevier Dnmt Elsevier H4K20me3 Elsevier BCIP Elsevier Kim1 Elsevier H3K27me3 Elsevier de Conti, Aline oth Furuya, Shinji oth Beland, Frederick A. oth Rusyn, Ivan oth Pogribny, Igor P. oth Enthalten in Elsevier Science Too late or too little? Potential for Alzheimer's disease passive immunotherapy via targeted intracerebroventricular delivery 2013 an international journal concerned with the effects of chemicals on living systems and immunotoxicology Amsterdam [u.a.] (DE-627)ELV011413085 volume:384 year:2017 day:1 month:06 pages:40-49 extent:10 https://doi.org/10.1016/j.tox.2017.03.004 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U GBV_ILN_22 GBV_ILN_40 GBV_ILN_105 52.56 Regenerative Energieformen alternative Energieformen VZ AR 384 2017 1 0601 40-49 10 045F 570
allfieldsGer	10.1016/j.tox.2017.03.004 doi GBVA2017009000026.pica (DE-627)ELV035858389 (ELSEVIER)S0300-483X(17)30074-4 DE-627 ger DE-627 rakwb eng 570 540 610 570 DE-600 540 DE-600 610 DE-600 610 VZ 530 VZ 52.56 bkl Dreval, Kostiantyn verfasserin aut miR-1247 blocks SOX9–mediated regeneration in alcohol- and fibrosis-associated acute kidney injury in mice 2017 10 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier • Alcohol and fibrosis-associated acute kidney injury is characterized by loss of the SOX9 protein. • The up-regulated microRNA miR-1247 targets the Sox9 mRNA. • The over-expression of miR-1247 is mediated by the elevation of histone H3 lysine 4 trimethylation. H3K56ac Elsevier H3K9me3 Elsevier HRP Elsevier EtOH Elsevier ChIP Elsevier ACTB Elsevier H4K16ac Elsevier Ngal Elsevier Havcr Elsevier H3K9ac Elsevier ANOVA Elsevier miRNA Elsevier Sox9 Elsevier CpG Elsevier AKI Elsevier MeDIP Elsevier PBS Elsevier NBT Elsevier SSC Elsevier DIG Elsevier CCl4 Elsevier Lcn2 Elsevier H3K4me3 Elsevier H3K27ac Elsevier GAPDH Elsevier AP Elsevier Dnmt Elsevier H4K20me3 Elsevier BCIP Elsevier Kim1 Elsevier H3K27me3 Elsevier de Conti, Aline oth Furuya, Shinji oth Beland, Frederick A. oth Rusyn, Ivan oth Pogribny, Igor P. oth Enthalten in Elsevier Science Too late or too little? Potential for Alzheimer's disease passive immunotherapy via targeted intracerebroventricular delivery 2013 an international journal concerned with the effects of chemicals on living systems and immunotoxicology Amsterdam [u.a.] (DE-627)ELV011413085 volume:384 year:2017 day:1 month:06 pages:40-49 extent:10 https://doi.org/10.1016/j.tox.2017.03.004 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U GBV_ILN_22 GBV_ILN_40 GBV_ILN_105 52.56 Regenerative Energieformen alternative Energieformen VZ AR 384 2017 1 0601 40-49 10 045F 570
allfieldsSound	10.1016/j.tox.2017.03.004 doi GBVA2017009000026.pica (DE-627)ELV035858389 (ELSEVIER)S0300-483X(17)30074-4 DE-627 ger DE-627 rakwb eng 570 540 610 570 DE-600 540 DE-600 610 DE-600 610 VZ 530 VZ 52.56 bkl Dreval, Kostiantyn verfasserin aut miR-1247 blocks SOX9–mediated regeneration in alcohol- and fibrosis-associated acute kidney injury in mice 2017 10 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier • Alcohol and fibrosis-associated acute kidney injury is characterized by loss of the SOX9 protein. • The up-regulated microRNA miR-1247 targets the Sox9 mRNA. • The over-expression of miR-1247 is mediated by the elevation of histone H3 lysine 4 trimethylation. H3K56ac Elsevier H3K9me3 Elsevier HRP Elsevier EtOH Elsevier ChIP Elsevier ACTB Elsevier H4K16ac Elsevier Ngal Elsevier Havcr Elsevier H3K9ac Elsevier ANOVA Elsevier miRNA Elsevier Sox9 Elsevier CpG Elsevier AKI Elsevier MeDIP Elsevier PBS Elsevier NBT Elsevier SSC Elsevier DIG Elsevier CCl4 Elsevier Lcn2 Elsevier H3K4me3 Elsevier H3K27ac Elsevier GAPDH Elsevier AP Elsevier Dnmt Elsevier H4K20me3 Elsevier BCIP Elsevier Kim1 Elsevier H3K27me3 Elsevier de Conti, Aline oth Furuya, Shinji oth Beland, Frederick A. oth Rusyn, Ivan oth Pogribny, Igor P. oth Enthalten in Elsevier Science Too late or too little? Potential for Alzheimer's disease passive immunotherapy via targeted intracerebroventricular delivery 2013 an international journal concerned with the effects of chemicals on living systems and immunotoxicology Amsterdam [u.a.] (DE-627)ELV011413085 volume:384 year:2017 day:1 month:06 pages:40-49 extent:10 https://doi.org/10.1016/j.tox.2017.03.004 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U GBV_ILN_22 GBV_ILN_40 GBV_ILN_105 52.56 Regenerative Energieformen alternative Energieformen VZ AR 384 2017 1 0601 40-49 10 045F 570
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source	Enthalten in Too late or too little? Potential for Alzheimer's disease passive immunotherapy via targeted intracerebroventricular delivery Amsterdam [u.a.] volume:384 year:2017 day:1 month:06 pages:40-49 extent:10
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topic_facet	H3K56ac H3K9me3 HRP EtOH ChIP ACTB H4K16ac Ngal Havcr H3K9ac ANOVA miRNA Sox9 CpG AKI MeDIP PBS NBT SSC DIG CCl4 Lcn2 H3K4me3 H3K27ac GAPDH AP Dnmt H4K20me3 BCIP Kim1 H3K27me3
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container_title	Too late or too little? Potential for Alzheimer's disease passive immunotherapy via targeted intracerebroventricular delivery
authorswithroles_txt_mv	Dreval, Kostiantyn @@aut@@ de Conti, Aline @@oth@@ Furuya, Shinji @@oth@@ Beland, Frederick A. @@oth@@ Rusyn, Ivan @@oth@@ Pogribny, Igor P. @@oth@@
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author	Dreval, Kostiantyn
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hierarchy_parent_title	Too late or too little? Potential for Alzheimer's disease passive immunotherapy via targeted intracerebroventricular delivery
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title	miR-1247 blocks SOX9–mediated regeneration in alcohol- and fibrosis-associated acute kidney injury in mice
ctrlnum	(DE-627)ELV035858389 (ELSEVIER)S0300-483X(17)30074-4
title_full	miR-1247 blocks SOX9–mediated regeneration in alcohol- and fibrosis-associated acute kidney injury in mice
author_sort	Dreval, Kostiantyn
journal	Too late or too little? Potential for Alzheimer's disease passive immunotherapy via targeted intracerebroventricular delivery
journalStr	Too late or too little? Potential for Alzheimer's disease passive immunotherapy via targeted intracerebroventricular delivery
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doi_str_mv	10.1016/j.tox.2017.03.004
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title_sort	mir-1247 blocks sox9–mediated regeneration in alcohol- and fibrosis-associated acute kidney injury in mice
title_auth	miR-1247 blocks SOX9–mediated regeneration in alcohol- and fibrosis-associated acute kidney injury in mice
abstract	• Alcohol and fibrosis-associated acute kidney injury is characterized by loss of the SOX9 protein. • The up-regulated microRNA miR-1247 targets the Sox9 mRNA. • The over-expression of miR-1247 is mediated by the elevation of histone H3 lysine 4 trimethylation.
abstractGer	• Alcohol and fibrosis-associated acute kidney injury is characterized by loss of the SOX9 protein. • The up-regulated microRNA miR-1247 targets the Sox9 mRNA. • The over-expression of miR-1247 is mediated by the elevation of histone H3 lysine 4 trimethylation.
abstract_unstemmed	• Alcohol and fibrosis-associated acute kidney injury is characterized by loss of the SOX9 protein. • The up-regulated microRNA miR-1247 targets the Sox9 mRNA. • The over-expression of miR-1247 is mediated by the elevation of histone H3 lysine 4 trimethylation.
collection_details	GBV_USEFLAG_U GBV_ELV SYSFLAG_U GBV_ILN_22 GBV_ILN_40 GBV_ILN_105
title_short	miR-1247 blocks SOX9–mediated regeneration in alcohol- and fibrosis-associated acute kidney injury in mice
url	https://doi.org/10.1016/j.tox.2017.03.004
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author2	de Conti, Aline Furuya, Shinji Beland, Frederick A. Rusyn, Ivan Pogribny, Igor P.
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up_date	2024-07-06T18:40:18.085Z
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