Acute low-dose endotoxin treatment results in improved whole-body glucose homeostasis in mice
Obese individuals present with an increased inflammatory tone as compared to healthy, normal-weight individuals, which is associated with insulin resistance. One factor hypothesized to contribute to increased inflammation in obese and diabetic states is elevated blood endotoxin levels, a condition k...
Ausführliche Beschreibung
Autor*in: |
Stevens, Joseph R. [verfasserIn] |
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Format: |
E-Artikel |
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Sprache: |
Englisch |
Erschienen: |
2017transfer abstract |
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Umfang: |
13 |
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Übergeordnetes Werk: |
Enthalten in: Energetic valorization of Nador lagoon algae and proposal to use it as a means of elimination of the eutrophication in this lagoon - El Asri, Ouahid ELSEVIER, 2017, clinical and experimental, Orlando, Fla |
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Übergeordnetes Werk: |
volume:68 ; year:2017 ; pages:150-162 ; extent:13 |
Links: |
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DOI / URN: |
10.1016/j.metabol.2016.12.008 |
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ELV036214159 |
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520 | |a Obese individuals present with an increased inflammatory tone as compared to healthy, normal-weight individuals, which is associated with insulin resistance. One factor hypothesized to contribute to increased inflammation in obese and diabetic states is elevated blood endotoxin levels, a condition known as metabolic endotoxemia. In non-obese and insulin sensitive individuals, circulating endotoxin concentrations fluctuate over the course of the day with elevations in the post-prandial state that return to baseline levels in the post-absorptive state. Evidence suggests that high-fat feeding alters these fluctuations causing endotoxin levels to remain high throughout the day. The effects of alterations in endotoxin levels on glucose metabolism are not clearly understood. | ||
520 | |a Obese individuals present with an increased inflammatory tone as compared to healthy, normal-weight individuals, which is associated with insulin resistance. One factor hypothesized to contribute to increased inflammation in obese and diabetic states is elevated blood endotoxin levels, a condition known as metabolic endotoxemia. In non-obese and insulin sensitive individuals, circulating endotoxin concentrations fluctuate over the course of the day with elevations in the post-prandial state that return to baseline levels in the post-absorptive state. Evidence suggests that high-fat feeding alters these fluctuations causing endotoxin levels to remain high throughout the day. The effects of alterations in endotoxin levels on glucose metabolism are not clearly understood. | ||
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10.1016/j.metabol.2016.12.008 doi GBV00000000000053A.pica (DE-627)ELV036214159 (ELSEVIER)S0026-0495(16)30186-X DE-627 ger DE-627 rakwb eng 610 610 DE-600 690 VZ 610 VZ 44.85 bkl Stevens, Joseph R. verfasserin aut Acute low-dose endotoxin treatment results in improved whole-body glucose homeostasis in mice 2017transfer abstract 13 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Obese individuals present with an increased inflammatory tone as compared to healthy, normal-weight individuals, which is associated with insulin resistance. One factor hypothesized to contribute to increased inflammation in obese and diabetic states is elevated blood endotoxin levels, a condition known as metabolic endotoxemia. In non-obese and insulin sensitive individuals, circulating endotoxin concentrations fluctuate over the course of the day with elevations in the post-prandial state that return to baseline levels in the post-absorptive state. Evidence suggests that high-fat feeding alters these fluctuations causing endotoxin levels to remain high throughout the day. The effects of alterations in endotoxin levels on glucose metabolism are not clearly understood. Obese individuals present with an increased inflammatory tone as compared to healthy, normal-weight individuals, which is associated with insulin resistance. One factor hypothesized to contribute to increased inflammation in obese and diabetic states is elevated blood endotoxin levels, a condition known as metabolic endotoxemia. In non-obese and insulin sensitive individuals, circulating endotoxin concentrations fluctuate over the course of the day with elevations in the post-prandial state that return to baseline levels in the post-absorptive state. Evidence suggests that high-fat feeding alters these fluctuations causing endotoxin levels to remain high throughout the day. The effects of alterations in endotoxin levels on glucose metabolism are not clearly understood. McMillan, Ryan P. oth Resendes, Justin T. oth Lloyd, Shannon K. oth Ali, Mostafa M. oth Frisard, Madlyn I. oth Hargett, Stefan oth Keller, Susanna R. oth Hulver, Matthew W. oth Enthalten in Elsevier El Asri, Ouahid ELSEVIER Energetic valorization of Nador lagoon algae and proposal to use it as a means of elimination of the eutrophication in this lagoon 2017 clinical and experimental Orlando, Fla (DE-627)ELV015296121 volume:68 year:2017 pages:150-162 extent:13 https://doi.org/10.1016/j.metabol.2016.12.008 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 44.85 Kardiologie Angiologie VZ AR 68 2017 150-162 13 045F 610 |
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10.1016/j.metabol.2016.12.008 doi GBV00000000000053A.pica (DE-627)ELV036214159 (ELSEVIER)S0026-0495(16)30186-X DE-627 ger DE-627 rakwb eng 610 610 DE-600 690 VZ 610 VZ 44.85 bkl Stevens, Joseph R. verfasserin aut Acute low-dose endotoxin treatment results in improved whole-body glucose homeostasis in mice 2017transfer abstract 13 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Obese individuals present with an increased inflammatory tone as compared to healthy, normal-weight individuals, which is associated with insulin resistance. One factor hypothesized to contribute to increased inflammation in obese and diabetic states is elevated blood endotoxin levels, a condition known as metabolic endotoxemia. In non-obese and insulin sensitive individuals, circulating endotoxin concentrations fluctuate over the course of the day with elevations in the post-prandial state that return to baseline levels in the post-absorptive state. Evidence suggests that high-fat feeding alters these fluctuations causing endotoxin levels to remain high throughout the day. The effects of alterations in endotoxin levels on glucose metabolism are not clearly understood. Obese individuals present with an increased inflammatory tone as compared to healthy, normal-weight individuals, which is associated with insulin resistance. One factor hypothesized to contribute to increased inflammation in obese and diabetic states is elevated blood endotoxin levels, a condition known as metabolic endotoxemia. In non-obese and insulin sensitive individuals, circulating endotoxin concentrations fluctuate over the course of the day with elevations in the post-prandial state that return to baseline levels in the post-absorptive state. Evidence suggests that high-fat feeding alters these fluctuations causing endotoxin levels to remain high throughout the day. The effects of alterations in endotoxin levels on glucose metabolism are not clearly understood. McMillan, Ryan P. oth Resendes, Justin T. oth Lloyd, Shannon K. oth Ali, Mostafa M. oth Frisard, Madlyn I. oth Hargett, Stefan oth Keller, Susanna R. oth Hulver, Matthew W. oth Enthalten in Elsevier El Asri, Ouahid ELSEVIER Energetic valorization of Nador lagoon algae and proposal to use it as a means of elimination of the eutrophication in this lagoon 2017 clinical and experimental Orlando, Fla (DE-627)ELV015296121 volume:68 year:2017 pages:150-162 extent:13 https://doi.org/10.1016/j.metabol.2016.12.008 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 44.85 Kardiologie Angiologie VZ AR 68 2017 150-162 13 045F 610 |
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10.1016/j.metabol.2016.12.008 doi GBV00000000000053A.pica (DE-627)ELV036214159 (ELSEVIER)S0026-0495(16)30186-X DE-627 ger DE-627 rakwb eng 610 610 DE-600 690 VZ 610 VZ 44.85 bkl Stevens, Joseph R. verfasserin aut Acute low-dose endotoxin treatment results in improved whole-body glucose homeostasis in mice 2017transfer abstract 13 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Obese individuals present with an increased inflammatory tone as compared to healthy, normal-weight individuals, which is associated with insulin resistance. One factor hypothesized to contribute to increased inflammation in obese and diabetic states is elevated blood endotoxin levels, a condition known as metabolic endotoxemia. In non-obese and insulin sensitive individuals, circulating endotoxin concentrations fluctuate over the course of the day with elevations in the post-prandial state that return to baseline levels in the post-absorptive state. Evidence suggests that high-fat feeding alters these fluctuations causing endotoxin levels to remain high throughout the day. The effects of alterations in endotoxin levels on glucose metabolism are not clearly understood. Obese individuals present with an increased inflammatory tone as compared to healthy, normal-weight individuals, which is associated with insulin resistance. One factor hypothesized to contribute to increased inflammation in obese and diabetic states is elevated blood endotoxin levels, a condition known as metabolic endotoxemia. In non-obese and insulin sensitive individuals, circulating endotoxin concentrations fluctuate over the course of the day with elevations in the post-prandial state that return to baseline levels in the post-absorptive state. Evidence suggests that high-fat feeding alters these fluctuations causing endotoxin levels to remain high throughout the day. The effects of alterations in endotoxin levels on glucose metabolism are not clearly understood. McMillan, Ryan P. oth Resendes, Justin T. oth Lloyd, Shannon K. oth Ali, Mostafa M. oth Frisard, Madlyn I. oth Hargett, Stefan oth Keller, Susanna R. oth Hulver, Matthew W. oth Enthalten in Elsevier El Asri, Ouahid ELSEVIER Energetic valorization of Nador lagoon algae and proposal to use it as a means of elimination of the eutrophication in this lagoon 2017 clinical and experimental Orlando, Fla (DE-627)ELV015296121 volume:68 year:2017 pages:150-162 extent:13 https://doi.org/10.1016/j.metabol.2016.12.008 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 44.85 Kardiologie Angiologie VZ AR 68 2017 150-162 13 045F 610 |
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10.1016/j.metabol.2016.12.008 doi GBV00000000000053A.pica (DE-627)ELV036214159 (ELSEVIER)S0026-0495(16)30186-X DE-627 ger DE-627 rakwb eng 610 610 DE-600 690 VZ 610 VZ 44.85 bkl Stevens, Joseph R. verfasserin aut Acute low-dose endotoxin treatment results in improved whole-body glucose homeostasis in mice 2017transfer abstract 13 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Obese individuals present with an increased inflammatory tone as compared to healthy, normal-weight individuals, which is associated with insulin resistance. One factor hypothesized to contribute to increased inflammation in obese and diabetic states is elevated blood endotoxin levels, a condition known as metabolic endotoxemia. In non-obese and insulin sensitive individuals, circulating endotoxin concentrations fluctuate over the course of the day with elevations in the post-prandial state that return to baseline levels in the post-absorptive state. Evidence suggests that high-fat feeding alters these fluctuations causing endotoxin levels to remain high throughout the day. The effects of alterations in endotoxin levels on glucose metabolism are not clearly understood. Obese individuals present with an increased inflammatory tone as compared to healthy, normal-weight individuals, which is associated with insulin resistance. One factor hypothesized to contribute to increased inflammation in obese and diabetic states is elevated blood endotoxin levels, a condition known as metabolic endotoxemia. In non-obese and insulin sensitive individuals, circulating endotoxin concentrations fluctuate over the course of the day with elevations in the post-prandial state that return to baseline levels in the post-absorptive state. Evidence suggests that high-fat feeding alters these fluctuations causing endotoxin levels to remain high throughout the day. The effects of alterations in endotoxin levels on glucose metabolism are not clearly understood. McMillan, Ryan P. oth Resendes, Justin T. oth Lloyd, Shannon K. oth Ali, Mostafa M. oth Frisard, Madlyn I. oth Hargett, Stefan oth Keller, Susanna R. oth Hulver, Matthew W. oth Enthalten in Elsevier El Asri, Ouahid ELSEVIER Energetic valorization of Nador lagoon algae and proposal to use it as a means of elimination of the eutrophication in this lagoon 2017 clinical and experimental Orlando, Fla (DE-627)ELV015296121 volume:68 year:2017 pages:150-162 extent:13 https://doi.org/10.1016/j.metabol.2016.12.008 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 44.85 Kardiologie Angiologie VZ AR 68 2017 150-162 13 045F 610 |
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10.1016/j.metabol.2016.12.008 doi GBV00000000000053A.pica (DE-627)ELV036214159 (ELSEVIER)S0026-0495(16)30186-X DE-627 ger DE-627 rakwb eng 610 610 DE-600 690 VZ 610 VZ 44.85 bkl Stevens, Joseph R. verfasserin aut Acute low-dose endotoxin treatment results in improved whole-body glucose homeostasis in mice 2017transfer abstract 13 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Obese individuals present with an increased inflammatory tone as compared to healthy, normal-weight individuals, which is associated with insulin resistance. One factor hypothesized to contribute to increased inflammation in obese and diabetic states is elevated blood endotoxin levels, a condition known as metabolic endotoxemia. In non-obese and insulin sensitive individuals, circulating endotoxin concentrations fluctuate over the course of the day with elevations in the post-prandial state that return to baseline levels in the post-absorptive state. Evidence suggests that high-fat feeding alters these fluctuations causing endotoxin levels to remain high throughout the day. The effects of alterations in endotoxin levels on glucose metabolism are not clearly understood. Obese individuals present with an increased inflammatory tone as compared to healthy, normal-weight individuals, which is associated with insulin resistance. One factor hypothesized to contribute to increased inflammation in obese and diabetic states is elevated blood endotoxin levels, a condition known as metabolic endotoxemia. In non-obese and insulin sensitive individuals, circulating endotoxin concentrations fluctuate over the course of the day with elevations in the post-prandial state that return to baseline levels in the post-absorptive state. Evidence suggests that high-fat feeding alters these fluctuations causing endotoxin levels to remain high throughout the day. The effects of alterations in endotoxin levels on glucose metabolism are not clearly understood. McMillan, Ryan P. oth Resendes, Justin T. oth Lloyd, Shannon K. oth Ali, Mostafa M. oth Frisard, Madlyn I. oth Hargett, Stefan oth Keller, Susanna R. oth Hulver, Matthew W. oth Enthalten in Elsevier El Asri, Ouahid ELSEVIER Energetic valorization of Nador lagoon algae and proposal to use it as a means of elimination of the eutrophication in this lagoon 2017 clinical and experimental Orlando, Fla (DE-627)ELV015296121 volume:68 year:2017 pages:150-162 extent:13 https://doi.org/10.1016/j.metabol.2016.12.008 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 44.85 Kardiologie Angiologie VZ AR 68 2017 150-162 13 045F 610 |
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title_full |
Acute low-dose endotoxin treatment results in improved whole-body glucose homeostasis in mice |
author_sort |
Stevens, Joseph R. |
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Energetic valorization of Nador lagoon algae and proposal to use it as a means of elimination of the eutrophication in this lagoon |
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Energetic valorization of Nador lagoon algae and proposal to use it as a means of elimination of the eutrophication in this lagoon |
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Stevens, Joseph R. |
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Stevens, Joseph R. |
doi_str_mv |
10.1016/j.metabol.2016.12.008 |
dewey-full |
610 690 |
title_sort |
acute low-dose endotoxin treatment results in improved whole-body glucose homeostasis in mice |
title_auth |
Acute low-dose endotoxin treatment results in improved whole-body glucose homeostasis in mice |
abstract |
Obese individuals present with an increased inflammatory tone as compared to healthy, normal-weight individuals, which is associated with insulin resistance. One factor hypothesized to contribute to increased inflammation in obese and diabetic states is elevated blood endotoxin levels, a condition known as metabolic endotoxemia. In non-obese and insulin sensitive individuals, circulating endotoxin concentrations fluctuate over the course of the day with elevations in the post-prandial state that return to baseline levels in the post-absorptive state. Evidence suggests that high-fat feeding alters these fluctuations causing endotoxin levels to remain high throughout the day. The effects of alterations in endotoxin levels on glucose metabolism are not clearly understood. |
abstractGer |
Obese individuals present with an increased inflammatory tone as compared to healthy, normal-weight individuals, which is associated with insulin resistance. One factor hypothesized to contribute to increased inflammation in obese and diabetic states is elevated blood endotoxin levels, a condition known as metabolic endotoxemia. In non-obese and insulin sensitive individuals, circulating endotoxin concentrations fluctuate over the course of the day with elevations in the post-prandial state that return to baseline levels in the post-absorptive state. Evidence suggests that high-fat feeding alters these fluctuations causing endotoxin levels to remain high throughout the day. The effects of alterations in endotoxin levels on glucose metabolism are not clearly understood. |
abstract_unstemmed |
Obese individuals present with an increased inflammatory tone as compared to healthy, normal-weight individuals, which is associated with insulin resistance. One factor hypothesized to contribute to increased inflammation in obese and diabetic states is elevated blood endotoxin levels, a condition known as metabolic endotoxemia. In non-obese and insulin sensitive individuals, circulating endotoxin concentrations fluctuate over the course of the day with elevations in the post-prandial state that return to baseline levels in the post-absorptive state. Evidence suggests that high-fat feeding alters these fluctuations causing endotoxin levels to remain high throughout the day. The effects of alterations in endotoxin levels on glucose metabolism are not clearly understood. |
collection_details |
GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA |
title_short |
Acute low-dose endotoxin treatment results in improved whole-body glucose homeostasis in mice |
url |
https://doi.org/10.1016/j.metabol.2016.12.008 |
remote_bool |
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author2 |
McMillan, Ryan P. Resendes, Justin T. Lloyd, Shannon K. Ali, Mostafa M. Frisard, Madlyn I. Hargett, Stefan Keller, Susanna R. Hulver, Matthew W. |
author2Str |
McMillan, Ryan P. Resendes, Justin T. Lloyd, Shannon K. Ali, Mostafa M. Frisard, Madlyn I. Hargett, Stefan Keller, Susanna R. Hulver, Matthew W. |
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doi_str |
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up_date |
2024-07-06T19:36:28.571Z |
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