Mouse models of diabetic retinopathy
Despite many years of clinical and laboratory investigation, diabetic retinopathy remains the leading cause of vision impairment among working-aged people. Mouse models have been valuable tools in further understanding the pathophysiology of diabetic retinopathy and discovering and assessing new pot...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Ramos, D. [verfasserIn] |
|---|
| Format: |
E-Artikel |
|---|---|
| Sprache: |
Englisch |
| Erschienen: |
2013 |
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| Umfang: |
12 |
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| Übergeordnetes Werk: |
Enthalten in: Contents - 2014, Amsterdam [u.a.] |
|---|---|
| Übergeordnetes Werk: |
volume:10 ; year:2013 ; number:4 ; pages:195-206 ; extent:12 |
| Links: |
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| DOI / URN: |
10.1016/j.ddmod.2014.02.002 |
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ELV038715716 |
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| 520 | |a Despite many years of clinical and laboratory investigation, diabetic retinopathy remains the leading cause of vision impairment among working-aged people. Mouse models have been valuable tools in further understanding the pathophysiology of diabetic retinopathy and discovering and assessing new potential therapeutic agents. However, although numerous diabetic mouse models have been developed, none of these models replicates all the key features of human diabetic retinopathy. In this review, we summarize and update the list of mouse diabetic and diabetic-like models that have been generated. | ||
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Despite many years of clinical and laboratory investigation, diabetic retinopathy remains the leading cause of vision impairment among working-aged people. Mouse models have been valuable tools in further understanding the pathophysiology of diabetic retinopathy and discovering and assessing new potential therapeutic agents. However, although numerous diabetic mouse models have been developed, none of these models replicates all the key features of human diabetic retinopathy. In this review, we summarize and update the list of mouse diabetic and diabetic-like models that have been generated. |
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Despite many years of clinical and laboratory investigation, diabetic retinopathy remains the leading cause of vision impairment among working-aged people. Mouse models have been valuable tools in further understanding the pathophysiology of diabetic retinopathy and discovering and assessing new potential therapeutic agents. However, although numerous diabetic mouse models have been developed, none of these models replicates all the key features of human diabetic retinopathy. In this review, we summarize and update the list of mouse diabetic and diabetic-like models that have been generated. |
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Despite many years of clinical and laboratory investigation, diabetic retinopathy remains the leading cause of vision impairment among working-aged people. Mouse models have been valuable tools in further understanding the pathophysiology of diabetic retinopathy and discovering and assessing new potential therapeutic agents. However, although numerous diabetic mouse models have been developed, none of these models replicates all the key features of human diabetic retinopathy. In this review, we summarize and update the list of mouse diabetic and diabetic-like models that have been generated. |
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<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">ELV038715716</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230624051533.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">180603s2013 xx |||||o 00| ||eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1016/j.ddmod.2014.02.002</subfield><subfield code="2">doi</subfield></datafield><datafield tag="028" ind1="5" ind2="2"><subfield code="a">GBVA2013007000017.pica</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)ELV038715716</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(ELSEVIER)S1740-6757(14)00007-3</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="082" ind1="0" ind2=" "><subfield code="a">610</subfield></datafield><datafield tag="082" ind1="0" ind2="4"><subfield code="a">610</subfield><subfield code="q">DE-600</subfield></datafield><datafield tag="082" ind1="0" ind2="4"><subfield code="a">150</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="082" ind1="0" ind2="4"><subfield code="a">610</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="082" ind1="0" ind2="4"><subfield code="a">530</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">33.00</subfield><subfield code="2">bkl</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Ramos, D.</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Mouse models of diabetic retinopathy</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2013</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">12</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zzz</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">z</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zu</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Despite many years of clinical and laboratory investigation, diabetic retinopathy remains the leading cause of vision impairment among working-aged people. 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7.399705 |