Stuck in traffic: an emerging theme in diseases of the nervous system
• The DNA sequencing revolution has revealed many new mutations in neurological diseases. • Many of these mutations affect proteins controlling endosomal/lysosomal transport. • A limited number of common cell-biological pathways are implicated in many cases. • Other proteins in these pathways are al...
Ausführliche Beschreibung
Autor*in: |
Neefjes, Jacques [verfasserIn] |
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Format: |
E-Artikel |
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Sprache: |
Englisch |
Erschienen: |
2014 |
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Schlagwörter: |
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Umfang: |
11 |
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Übergeordnetes Werk: |
Enthalten in: Ultimate nanopatterning of Si substrate using filtered liquid metal alloy ion source-focused ion beam - Benkouider, A. ELSEVIER, 2013, TINS, Amsterdam [u.a.] |
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Übergeordnetes Werk: |
volume:37 ; year:2014 ; number:2 ; pages:66-76 ; extent:11 |
Links: |
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DOI / URN: |
10.1016/j.tins.2013.11.006 |
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ELV039233626 |
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10.1016/j.tins.2013.11.006 doi GBVA2014005000021.pica (DE-627)ELV039233626 (ELSEVIER)S0166-2236(13)00228-2 DE-627 ger DE-627 rakwb eng 610 610 DE-600 070 VZ 660 VZ 333.7 610 VZ 43.12 bkl 43.13 bkl 44.13 bkl Neefjes, Jacques verfasserin aut Stuck in traffic: an emerging theme in diseases of the nervous system 2014 11 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier • The DNA sequencing revolution has revealed many new mutations in neurological diseases. • Many of these mutations affect proteins controlling endosomal/lysosomal transport. • A limited number of common cell-biological pathways are implicated in many cases. • Other proteins in these pathways are also predicted to yield neurological diseases. • Druggable nodes in these pathways may be defined for new/individualized treatments. protein trafficking Elsevier Parkinson's disease Elsevier hereditary spastic paraplegia Elsevier neurological disease Elsevier Charcot-Marie-Tooth disease Elsevier Alzheimer's disease Elsevier endo-lysosomal system Elsevier amyothoropic lateral sclerosis Elsevier van der Kant, Rik oth Enthalten in Elsevier Science Benkouider, A. ELSEVIER Ultimate nanopatterning of Si substrate using filtered liquid metal alloy ion source-focused ion beam 2013 TINS Amsterdam [u.a.] (DE-627)ELV011304014 volume:37 year:2014 number:2 pages:66-76 extent:11 https://doi.org/10.1016/j.tins.2013.11.006 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA SSG-OPC-GGO GBV_ILN_21 GBV_ILN_22 GBV_ILN_40 GBV_ILN_70 GBV_ILN_110 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2015 GBV_ILN_2021 GBV_ILN_2031 GBV_ILN_2032 GBV_ILN_2356 GBV_ILN_2523 43.12 Umweltchemie VZ 43.13 Umwelttoxikologie VZ 44.13 Medizinische Ökologie VZ AR 37 2014 2 66-76 11 045F 610 |
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10.1016/j.tins.2013.11.006 doi GBVA2014005000021.pica (DE-627)ELV039233626 (ELSEVIER)S0166-2236(13)00228-2 DE-627 ger DE-627 rakwb eng 610 610 DE-600 070 VZ 660 VZ 333.7 610 VZ 43.12 bkl 43.13 bkl 44.13 bkl Neefjes, Jacques verfasserin aut Stuck in traffic: an emerging theme in diseases of the nervous system 2014 11 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier • The DNA sequencing revolution has revealed many new mutations in neurological diseases. • Many of these mutations affect proteins controlling endosomal/lysosomal transport. • A limited number of common cell-biological pathways are implicated in many cases. • Other proteins in these pathways are also predicted to yield neurological diseases. • Druggable nodes in these pathways may be defined for new/individualized treatments. protein trafficking Elsevier Parkinson's disease Elsevier hereditary spastic paraplegia Elsevier neurological disease Elsevier Charcot-Marie-Tooth disease Elsevier Alzheimer's disease Elsevier endo-lysosomal system Elsevier amyothoropic lateral sclerosis Elsevier van der Kant, Rik oth Enthalten in Elsevier Science Benkouider, A. ELSEVIER Ultimate nanopatterning of Si substrate using filtered liquid metal alloy ion source-focused ion beam 2013 TINS Amsterdam [u.a.] (DE-627)ELV011304014 volume:37 year:2014 number:2 pages:66-76 extent:11 https://doi.org/10.1016/j.tins.2013.11.006 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA SSG-OPC-GGO GBV_ILN_21 GBV_ILN_22 GBV_ILN_40 GBV_ILN_70 GBV_ILN_110 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2015 GBV_ILN_2021 GBV_ILN_2031 GBV_ILN_2032 GBV_ILN_2356 GBV_ILN_2523 43.12 Umweltchemie VZ 43.13 Umwelttoxikologie VZ 44.13 Medizinische Ökologie VZ AR 37 2014 2 66-76 11 045F 610 |
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10.1016/j.tins.2013.11.006 doi GBVA2014005000021.pica (DE-627)ELV039233626 (ELSEVIER)S0166-2236(13)00228-2 DE-627 ger DE-627 rakwb eng 610 610 DE-600 070 VZ 660 VZ 333.7 610 VZ 43.12 bkl 43.13 bkl 44.13 bkl Neefjes, Jacques verfasserin aut Stuck in traffic: an emerging theme in diseases of the nervous system 2014 11 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier • The DNA sequencing revolution has revealed many new mutations in neurological diseases. • Many of these mutations affect proteins controlling endosomal/lysosomal transport. • A limited number of common cell-biological pathways are implicated in many cases. • Other proteins in these pathways are also predicted to yield neurological diseases. • Druggable nodes in these pathways may be defined for new/individualized treatments. protein trafficking Elsevier Parkinson's disease Elsevier hereditary spastic paraplegia Elsevier neurological disease Elsevier Charcot-Marie-Tooth disease Elsevier Alzheimer's disease Elsevier endo-lysosomal system Elsevier amyothoropic lateral sclerosis Elsevier van der Kant, Rik oth Enthalten in Elsevier Science Benkouider, A. ELSEVIER Ultimate nanopatterning of Si substrate using filtered liquid metal alloy ion source-focused ion beam 2013 TINS Amsterdam [u.a.] (DE-627)ELV011304014 volume:37 year:2014 number:2 pages:66-76 extent:11 https://doi.org/10.1016/j.tins.2013.11.006 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA SSG-OPC-GGO GBV_ILN_21 GBV_ILN_22 GBV_ILN_40 GBV_ILN_70 GBV_ILN_110 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2015 GBV_ILN_2021 GBV_ILN_2031 GBV_ILN_2032 GBV_ILN_2356 GBV_ILN_2523 43.12 Umweltchemie VZ 43.13 Umwelttoxikologie VZ 44.13 Medizinische Ökologie VZ AR 37 2014 2 66-76 11 045F 610 |
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10.1016/j.tins.2013.11.006 doi GBVA2014005000021.pica (DE-627)ELV039233626 (ELSEVIER)S0166-2236(13)00228-2 DE-627 ger DE-627 rakwb eng 610 610 DE-600 070 VZ 660 VZ 333.7 610 VZ 43.12 bkl 43.13 bkl 44.13 bkl Neefjes, Jacques verfasserin aut Stuck in traffic: an emerging theme in diseases of the nervous system 2014 11 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier • The DNA sequencing revolution has revealed many new mutations in neurological diseases. • Many of these mutations affect proteins controlling endosomal/lysosomal transport. • A limited number of common cell-biological pathways are implicated in many cases. • Other proteins in these pathways are also predicted to yield neurological diseases. • Druggable nodes in these pathways may be defined for new/individualized treatments. protein trafficking Elsevier Parkinson's disease Elsevier hereditary spastic paraplegia Elsevier neurological disease Elsevier Charcot-Marie-Tooth disease Elsevier Alzheimer's disease Elsevier endo-lysosomal system Elsevier amyothoropic lateral sclerosis Elsevier van der Kant, Rik oth Enthalten in Elsevier Science Benkouider, A. ELSEVIER Ultimate nanopatterning of Si substrate using filtered liquid metal alloy ion source-focused ion beam 2013 TINS Amsterdam [u.a.] (DE-627)ELV011304014 volume:37 year:2014 number:2 pages:66-76 extent:11 https://doi.org/10.1016/j.tins.2013.11.006 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA SSG-OPC-GGO GBV_ILN_21 GBV_ILN_22 GBV_ILN_40 GBV_ILN_70 GBV_ILN_110 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2015 GBV_ILN_2021 GBV_ILN_2031 GBV_ILN_2032 GBV_ILN_2356 GBV_ILN_2523 43.12 Umweltchemie VZ 43.13 Umwelttoxikologie VZ 44.13 Medizinische Ökologie VZ AR 37 2014 2 66-76 11 045F 610 |
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10.1016/j.tins.2013.11.006 doi GBVA2014005000021.pica (DE-627)ELV039233626 (ELSEVIER)S0166-2236(13)00228-2 DE-627 ger DE-627 rakwb eng 610 610 DE-600 070 VZ 660 VZ 333.7 610 VZ 43.12 bkl 43.13 bkl 44.13 bkl Neefjes, Jacques verfasserin aut Stuck in traffic: an emerging theme in diseases of the nervous system 2014 11 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier • The DNA sequencing revolution has revealed many new mutations in neurological diseases. • Many of these mutations affect proteins controlling endosomal/lysosomal transport. • A limited number of common cell-biological pathways are implicated in many cases. • Other proteins in these pathways are also predicted to yield neurological diseases. • Druggable nodes in these pathways may be defined for new/individualized treatments. protein trafficking Elsevier Parkinson's disease Elsevier hereditary spastic paraplegia Elsevier neurological disease Elsevier Charcot-Marie-Tooth disease Elsevier Alzheimer's disease Elsevier endo-lysosomal system Elsevier amyothoropic lateral sclerosis Elsevier van der Kant, Rik oth Enthalten in Elsevier Science Benkouider, A. ELSEVIER Ultimate nanopatterning of Si substrate using filtered liquid metal alloy ion source-focused ion beam 2013 TINS Amsterdam [u.a.] (DE-627)ELV011304014 volume:37 year:2014 number:2 pages:66-76 extent:11 https://doi.org/10.1016/j.tins.2013.11.006 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA SSG-OPC-GGO GBV_ILN_21 GBV_ILN_22 GBV_ILN_40 GBV_ILN_70 GBV_ILN_110 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2015 GBV_ILN_2021 GBV_ILN_2031 GBV_ILN_2032 GBV_ILN_2356 GBV_ILN_2523 43.12 Umweltchemie VZ 43.13 Umwelttoxikologie VZ 44.13 Medizinische Ökologie VZ AR 37 2014 2 66-76 11 045F 610 |
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Ultimate nanopatterning of Si substrate using filtered liquid metal alloy ion source-focused ion beam |
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Ultimate nanopatterning of Si substrate using filtered liquid metal alloy ion source-focused ion beam |
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Stuck in traffic: an emerging theme in diseases of the nervous system |
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• The DNA sequencing revolution has revealed many new mutations in neurological diseases. • Many of these mutations affect proteins controlling endosomal/lysosomal transport. • A limited number of common cell-biological pathways are implicated in many cases. • Other proteins in these pathways are also predicted to yield neurological diseases. • Druggable nodes in these pathways may be defined for new/individualized treatments. |
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• The DNA sequencing revolution has revealed many new mutations in neurological diseases. • Many of these mutations affect proteins controlling endosomal/lysosomal transport. • A limited number of common cell-biological pathways are implicated in many cases. • Other proteins in these pathways are also predicted to yield neurological diseases. • Druggable nodes in these pathways may be defined for new/individualized treatments. |
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• The DNA sequencing revolution has revealed many new mutations in neurological diseases. • Many of these mutations affect proteins controlling endosomal/lysosomal transport. • A limited number of common cell-biological pathways are implicated in many cases. • Other proteins in these pathways are also predicted to yield neurological diseases. • Druggable nodes in these pathways may be defined for new/individualized treatments. |
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