Stuck in traffic: an emerging theme in diseases of the nervous system
• The DNA sequencing revolution has revealed many new mutations in neurological diseases. • Many of these mutations affect proteins controlling endosomal/lysosomal transport. • A limited number of common cell-biological pathways are implicated in many cases. • Other proteins in these pathways are al...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Neefjes, Jacques [verfasserIn] |
|---|
| Format: |
E-Artikel |
|---|---|
| Sprache: |
Englisch |
| Erschienen: |
2014 |
|---|
| Schlagwörter: |
|---|
| Umfang: |
11 |
|---|
| Übergeordnetes Werk: |
Enthalten in: Ultimate nanopatterning of Si substrate using filtered liquid metal alloy ion source-focused ion beam - Benkouider, A. ELSEVIER, 2013, TINS, Amsterdam [u.a.] |
|---|---|
| Übergeordnetes Werk: |
volume:37 ; year:2014 ; number:2 ; pages:66-76 ; extent:11 |
| Links: |
|---|
| DOI / URN: |
10.1016/j.tins.2013.11.006 |
|---|
| Katalog-ID: |
ELV039233626 |
|---|
| LEADER | 01000caa a22002652 4500 | ||
|---|---|---|---|
| 001 | ELV039233626 | ||
| 003 | DE-627 | ||
| 005 | 20230624055533.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 180603s2014 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1016/j.tins.2013.11.006 |2 doi | |
| 028 | 5 | 2 | |a GBVA2014005000021.pica |
| 035 | |a (DE-627)ELV039233626 | ||
| 035 | |a (ELSEVIER)S0166-2236(13)00228-2 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 082 | 0 | |a 610 | |
| 082 | 0 | 4 | |a 610 |q DE-600 |
| 082 | 0 | 4 | |a 070 |q VZ |
| 082 | 0 | 4 | |a 660 |q VZ |
| 082 | 0 | 4 | |a 333.7 |a 610 |q VZ |
| 084 | |a 43.12 |2 bkl | ||
| 084 | |a 43.13 |2 bkl | ||
| 084 | |a 44.13 |2 bkl | ||
| 100 | 1 | |a Neefjes, Jacques |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Stuck in traffic: an emerging theme in diseases of the nervous system |
| 264 | 1 | |c 2014 | |
| 300 | |a 11 | ||
| 336 | |a nicht spezifiziert |b zzz |2 rdacontent | ||
| 337 | |a nicht spezifiziert |b z |2 rdamedia | ||
| 338 | |a nicht spezifiziert |b zu |2 rdacarrier | ||
| 520 | |a • The DNA sequencing revolution has revealed many new mutations in neurological diseases. • Many of these mutations affect proteins controlling endosomal/lysosomal transport. • A limited number of common cell-biological pathways are implicated in many cases. • Other proteins in these pathways are also predicted to yield neurological diseases. • Druggable nodes in these pathways may be defined for new/individualized treatments. | ||
| 650 | 7 | |a protein trafficking |2 Elsevier | |
| 650 | 7 | |a Parkinson's disease |2 Elsevier | |
| 650 | 7 | |a hereditary spastic paraplegia |2 Elsevier | |
| 650 | 7 | |a neurological disease |2 Elsevier | |
| 650 | 7 | |a Charcot-Marie-Tooth disease |2 Elsevier | |
| 650 | 7 | |a Alzheimer's disease |2 Elsevier | |
| 650 | 7 | |a endo-lysosomal system |2 Elsevier | |
| 650 | 7 | |a amyothoropic lateral sclerosis |2 Elsevier | |
| 700 | 1 | |a van der Kant, Rik |4 oth | |
| 773 | 0 | 8 | |i Enthalten in |n Elsevier Science |a Benkouider, A. ELSEVIER |t Ultimate nanopatterning of Si substrate using filtered liquid metal alloy ion source-focused ion beam |d 2013 |d TINS |g Amsterdam [u.a.] |w (DE-627)ELV011304014 |
| 773 | 1 | 8 | |g volume:37 |g year:2014 |g number:2 |g pages:66-76 |g extent:11 |
| 856 | 4 | 0 | |u https://doi.org/10.1016/j.tins.2013.11.006 |3 Volltext |
| 912 | |a GBV_USEFLAG_U | ||
| 912 | |a GBV_ELV | ||
| 912 | |a SYSFLAG_U | ||
| 912 | |a SSG-OLC-PHA | ||
| 912 | |a SSG-OPC-GGO | ||
| 912 | |a GBV_ILN_21 | ||
| 912 | |a GBV_ILN_22 | ||
| 912 | |a GBV_ILN_40 | ||
| 912 | |a GBV_ILN_70 | ||
| 912 | |a GBV_ILN_110 | ||
| 912 | |a GBV_ILN_2004 | ||
| 912 | |a GBV_ILN_2005 | ||
| 912 | |a GBV_ILN_2009 | ||
| 912 | |a GBV_ILN_2015 | ||
| 912 | |a GBV_ILN_2021 | ||
| 912 | |a GBV_ILN_2031 | ||
| 912 | |a GBV_ILN_2032 | ||
| 912 | |a GBV_ILN_2356 | ||
| 912 | |a GBV_ILN_2523 | ||
| 936 | b | k | |a 43.12 |j Umweltchemie |q VZ |
| 936 | b | k | |a 43.13 |j Umwelttoxikologie |q VZ |
| 936 | b | k | |a 44.13 |j Medizinische Ökologie |q VZ |
| 951 | |a AR | ||
| 952 | |d 37 |j 2014 |e 2 |h 66-76 |g 11 | ||
| 953 | |2 045F |a 610 | ||
| author_variant |
j n jn |
|---|---|
| matchkey_str |
neefjesjacquesvanderkantrik:2014----:tcitafcnmrighmidsaeot |
| hierarchy_sort_str |
2014 |
| bklnumber |
43.12 43.13 44.13 |
| publishDate |
2014 |
| allfields |
10.1016/j.tins.2013.11.006 doi GBVA2014005000021.pica (DE-627)ELV039233626 (ELSEVIER)S0166-2236(13)00228-2 DE-627 ger DE-627 rakwb eng 610 610 DE-600 070 VZ 660 VZ 333.7 610 VZ 43.12 bkl 43.13 bkl 44.13 bkl Neefjes, Jacques verfasserin aut Stuck in traffic: an emerging theme in diseases of the nervous system 2014 11 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier • The DNA sequencing revolution has revealed many new mutations in neurological diseases. • Many of these mutations affect proteins controlling endosomal/lysosomal transport. • A limited number of common cell-biological pathways are implicated in many cases. • Other proteins in these pathways are also predicted to yield neurological diseases. • Druggable nodes in these pathways may be defined for new/individualized treatments. protein trafficking Elsevier Parkinson's disease Elsevier hereditary spastic paraplegia Elsevier neurological disease Elsevier Charcot-Marie-Tooth disease Elsevier Alzheimer's disease Elsevier endo-lysosomal system Elsevier amyothoropic lateral sclerosis Elsevier van der Kant, Rik oth Enthalten in Elsevier Science Benkouider, A. ELSEVIER Ultimate nanopatterning of Si substrate using filtered liquid metal alloy ion source-focused ion beam 2013 TINS Amsterdam [u.a.] (DE-627)ELV011304014 volume:37 year:2014 number:2 pages:66-76 extent:11 https://doi.org/10.1016/j.tins.2013.11.006 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA SSG-OPC-GGO GBV_ILN_21 GBV_ILN_22 GBV_ILN_40 GBV_ILN_70 GBV_ILN_110 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2015 GBV_ILN_2021 GBV_ILN_2031 GBV_ILN_2032 GBV_ILN_2356 GBV_ILN_2523 43.12 Umweltchemie VZ 43.13 Umwelttoxikologie VZ 44.13 Medizinische Ökologie VZ AR 37 2014 2 66-76 11 045F 610 |
| spelling |
10.1016/j.tins.2013.11.006 doi GBVA2014005000021.pica (DE-627)ELV039233626 (ELSEVIER)S0166-2236(13)00228-2 DE-627 ger DE-627 rakwb eng 610 610 DE-600 070 VZ 660 VZ 333.7 610 VZ 43.12 bkl 43.13 bkl 44.13 bkl Neefjes, Jacques verfasserin aut Stuck in traffic: an emerging theme in diseases of the nervous system 2014 11 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier • The DNA sequencing revolution has revealed many new mutations in neurological diseases. • Many of these mutations affect proteins controlling endosomal/lysosomal transport. • A limited number of common cell-biological pathways are implicated in many cases. • Other proteins in these pathways are also predicted to yield neurological diseases. • Druggable nodes in these pathways may be defined for new/individualized treatments. protein trafficking Elsevier Parkinson's disease Elsevier hereditary spastic paraplegia Elsevier neurological disease Elsevier Charcot-Marie-Tooth disease Elsevier Alzheimer's disease Elsevier endo-lysosomal system Elsevier amyothoropic lateral sclerosis Elsevier van der Kant, Rik oth Enthalten in Elsevier Science Benkouider, A. ELSEVIER Ultimate nanopatterning of Si substrate using filtered liquid metal alloy ion source-focused ion beam 2013 TINS Amsterdam [u.a.] (DE-627)ELV011304014 volume:37 year:2014 number:2 pages:66-76 extent:11 https://doi.org/10.1016/j.tins.2013.11.006 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA SSG-OPC-GGO GBV_ILN_21 GBV_ILN_22 GBV_ILN_40 GBV_ILN_70 GBV_ILN_110 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2015 GBV_ILN_2021 GBV_ILN_2031 GBV_ILN_2032 GBV_ILN_2356 GBV_ILN_2523 43.12 Umweltchemie VZ 43.13 Umwelttoxikologie VZ 44.13 Medizinische Ökologie VZ AR 37 2014 2 66-76 11 045F 610 |
| allfields_unstemmed |
10.1016/j.tins.2013.11.006 doi GBVA2014005000021.pica (DE-627)ELV039233626 (ELSEVIER)S0166-2236(13)00228-2 DE-627 ger DE-627 rakwb eng 610 610 DE-600 070 VZ 660 VZ 333.7 610 VZ 43.12 bkl 43.13 bkl 44.13 bkl Neefjes, Jacques verfasserin aut Stuck in traffic: an emerging theme in diseases of the nervous system 2014 11 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier • The DNA sequencing revolution has revealed many new mutations in neurological diseases. • Many of these mutations affect proteins controlling endosomal/lysosomal transport. • A limited number of common cell-biological pathways are implicated in many cases. • Other proteins in these pathways are also predicted to yield neurological diseases. • Druggable nodes in these pathways may be defined for new/individualized treatments. protein trafficking Elsevier Parkinson's disease Elsevier hereditary spastic paraplegia Elsevier neurological disease Elsevier Charcot-Marie-Tooth disease Elsevier Alzheimer's disease Elsevier endo-lysosomal system Elsevier amyothoropic lateral sclerosis Elsevier van der Kant, Rik oth Enthalten in Elsevier Science Benkouider, A. ELSEVIER Ultimate nanopatterning of Si substrate using filtered liquid metal alloy ion source-focused ion beam 2013 TINS Amsterdam [u.a.] (DE-627)ELV011304014 volume:37 year:2014 number:2 pages:66-76 extent:11 https://doi.org/10.1016/j.tins.2013.11.006 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA SSG-OPC-GGO GBV_ILN_21 GBV_ILN_22 GBV_ILN_40 GBV_ILN_70 GBV_ILN_110 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2015 GBV_ILN_2021 GBV_ILN_2031 GBV_ILN_2032 GBV_ILN_2356 GBV_ILN_2523 43.12 Umweltchemie VZ 43.13 Umwelttoxikologie VZ 44.13 Medizinische Ökologie VZ AR 37 2014 2 66-76 11 045F 610 |
| allfieldsGer |
10.1016/j.tins.2013.11.006 doi GBVA2014005000021.pica (DE-627)ELV039233626 (ELSEVIER)S0166-2236(13)00228-2 DE-627 ger DE-627 rakwb eng 610 610 DE-600 070 VZ 660 VZ 333.7 610 VZ 43.12 bkl 43.13 bkl 44.13 bkl Neefjes, Jacques verfasserin aut Stuck in traffic: an emerging theme in diseases of the nervous system 2014 11 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier • The DNA sequencing revolution has revealed many new mutations in neurological diseases. • Many of these mutations affect proteins controlling endosomal/lysosomal transport. • A limited number of common cell-biological pathways are implicated in many cases. • Other proteins in these pathways are also predicted to yield neurological diseases. • Druggable nodes in these pathways may be defined for new/individualized treatments. protein trafficking Elsevier Parkinson's disease Elsevier hereditary spastic paraplegia Elsevier neurological disease Elsevier Charcot-Marie-Tooth disease Elsevier Alzheimer's disease Elsevier endo-lysosomal system Elsevier amyothoropic lateral sclerosis Elsevier van der Kant, Rik oth Enthalten in Elsevier Science Benkouider, A. ELSEVIER Ultimate nanopatterning of Si substrate using filtered liquid metal alloy ion source-focused ion beam 2013 TINS Amsterdam [u.a.] (DE-627)ELV011304014 volume:37 year:2014 number:2 pages:66-76 extent:11 https://doi.org/10.1016/j.tins.2013.11.006 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA SSG-OPC-GGO GBV_ILN_21 GBV_ILN_22 GBV_ILN_40 GBV_ILN_70 GBV_ILN_110 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2015 GBV_ILN_2021 GBV_ILN_2031 GBV_ILN_2032 GBV_ILN_2356 GBV_ILN_2523 43.12 Umweltchemie VZ 43.13 Umwelttoxikologie VZ 44.13 Medizinische Ökologie VZ AR 37 2014 2 66-76 11 045F 610 |
| allfieldsSound |
10.1016/j.tins.2013.11.006 doi GBVA2014005000021.pica (DE-627)ELV039233626 (ELSEVIER)S0166-2236(13)00228-2 DE-627 ger DE-627 rakwb eng 610 610 DE-600 070 VZ 660 VZ 333.7 610 VZ 43.12 bkl 43.13 bkl 44.13 bkl Neefjes, Jacques verfasserin aut Stuck in traffic: an emerging theme in diseases of the nervous system 2014 11 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier • The DNA sequencing revolution has revealed many new mutations in neurological diseases. • Many of these mutations affect proteins controlling endosomal/lysosomal transport. • A limited number of common cell-biological pathways are implicated in many cases. • Other proteins in these pathways are also predicted to yield neurological diseases. • Druggable nodes in these pathways may be defined for new/individualized treatments. protein trafficking Elsevier Parkinson's disease Elsevier hereditary spastic paraplegia Elsevier neurological disease Elsevier Charcot-Marie-Tooth disease Elsevier Alzheimer's disease Elsevier endo-lysosomal system Elsevier amyothoropic lateral sclerosis Elsevier van der Kant, Rik oth Enthalten in Elsevier Science Benkouider, A. ELSEVIER Ultimate nanopatterning of Si substrate using filtered liquid metal alloy ion source-focused ion beam 2013 TINS Amsterdam [u.a.] (DE-627)ELV011304014 volume:37 year:2014 number:2 pages:66-76 extent:11 https://doi.org/10.1016/j.tins.2013.11.006 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA SSG-OPC-GGO GBV_ILN_21 GBV_ILN_22 GBV_ILN_40 GBV_ILN_70 GBV_ILN_110 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2015 GBV_ILN_2021 GBV_ILN_2031 GBV_ILN_2032 GBV_ILN_2356 GBV_ILN_2523 43.12 Umweltchemie VZ 43.13 Umwelttoxikologie VZ 44.13 Medizinische Ökologie VZ AR 37 2014 2 66-76 11 045F 610 |
| language |
English |
| source |
Enthalten in Ultimate nanopatterning of Si substrate using filtered liquid metal alloy ion source-focused ion beam Amsterdam [u.a.] volume:37 year:2014 number:2 pages:66-76 extent:11 |
| sourceStr |
Enthalten in Ultimate nanopatterning of Si substrate using filtered liquid metal alloy ion source-focused ion beam Amsterdam [u.a.] volume:37 year:2014 number:2 pages:66-76 extent:11 |
| format_phy_str_mv |
Article |
| bklname |
Umweltchemie Umwelttoxikologie Medizinische Ökologie |
| institution |
findex.gbv.de |
| topic_facet |
protein trafficking Parkinson's disease hereditary spastic paraplegia neurological disease Charcot-Marie-Tooth disease Alzheimer's disease endo-lysosomal system amyothoropic lateral sclerosis |
| dewey-raw |
610 |
| isfreeaccess_bool |
false |
| container_title |
Ultimate nanopatterning of Si substrate using filtered liquid metal alloy ion source-focused ion beam |
| authorswithroles_txt_mv |
Neefjes, Jacques @@aut@@ van der Kant, Rik @@oth@@ |
| publishDateDaySort_date |
2014-01-01T00:00:00Z |
| hierarchy_top_id |
ELV011304014 |
| dewey-sort |
3610 |
| id |
ELV039233626 |
| language_de |
englisch |
| fullrecord |
<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">ELV039233626</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230624055533.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">180603s2014 xx |||||o 00| ||eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1016/j.tins.2013.11.006</subfield><subfield code="2">doi</subfield></datafield><datafield tag="028" ind1="5" ind2="2"><subfield code="a">GBVA2014005000021.pica</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)ELV039233626</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(ELSEVIER)S0166-2236(13)00228-2</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="082" ind1="0" ind2=" "><subfield code="a">610</subfield></datafield><datafield tag="082" ind1="0" ind2="4"><subfield code="a">610</subfield><subfield code="q">DE-600</subfield></datafield><datafield tag="082" ind1="0" ind2="4"><subfield code="a">070</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="082" ind1="0" ind2="4"><subfield code="a">660</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="082" ind1="0" ind2="4"><subfield code="a">333.7</subfield><subfield code="a">610</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">43.12</subfield><subfield code="2">bkl</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">43.13</subfield><subfield code="2">bkl</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">44.13</subfield><subfield code="2">bkl</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Neefjes, Jacques</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Stuck in traffic: an emerging theme in diseases of the nervous system</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2014</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">11</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zzz</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">z</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zu</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">• The DNA sequencing revolution has revealed many new mutations in neurological diseases. • Many of these mutations affect proteins controlling endosomal/lysosomal transport. • A limited number of common cell-biological pathways are implicated in many cases. • Other proteins in these pathways are also predicted to yield neurological diseases. • Druggable nodes in these pathways may be defined for new/individualized treatments.</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">protein trafficking</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Parkinson's disease</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">hereditary spastic paraplegia</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">neurological disease</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Charcot-Marie-Tooth disease</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Alzheimer's disease</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">endo-lysosomal system</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">amyothoropic lateral sclerosis</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">van der Kant, Rik</subfield><subfield code="4">oth</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">Enthalten in</subfield><subfield code="n">Elsevier Science</subfield><subfield code="a">Benkouider, A. ELSEVIER</subfield><subfield code="t">Ultimate nanopatterning of Si substrate using filtered liquid metal alloy ion source-focused ion beam</subfield><subfield code="d">2013</subfield><subfield code="d">TINS</subfield><subfield code="g">Amsterdam [u.a.]</subfield><subfield code="w">(DE-627)ELV011304014</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:37</subfield><subfield code="g">year:2014</subfield><subfield code="g">number:2</subfield><subfield code="g">pages:66-76</subfield><subfield code="g">extent:11</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://doi.org/10.1016/j.tins.2013.11.006</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_U</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ELV</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SYSFLAG_U</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SSG-OLC-PHA</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SSG-OPC-GGO</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_21</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_22</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_40</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_70</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_110</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2004</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2005</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2009</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2015</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2021</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2031</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2032</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2356</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2523</subfield></datafield><datafield tag="936" ind1="b" ind2="k"><subfield code="a">43.12</subfield><subfield code="j">Umweltchemie</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="936" ind1="b" ind2="k"><subfield code="a">43.13</subfield><subfield code="j">Umwelttoxikologie</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="936" ind1="b" ind2="k"><subfield code="a">44.13</subfield><subfield code="j">Medizinische Ökologie</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">37</subfield><subfield code="j">2014</subfield><subfield code="e">2</subfield><subfield code="h">66-76</subfield><subfield code="g">11</subfield></datafield><datafield tag="953" ind1=" " ind2=" "><subfield code="2">045F</subfield><subfield code="a">610</subfield></datafield></record></collection>
|
| author |
Neefjes, Jacques |
| spellingShingle |
Neefjes, Jacques ddc 610 ddc 070 ddc 660 ddc 333.7 bkl 43.12 bkl 43.13 bkl 44.13 Elsevier protein trafficking Elsevier Parkinson's disease Elsevier hereditary spastic paraplegia Elsevier neurological disease Elsevier Charcot-Marie-Tooth disease Elsevier Alzheimer's disease Elsevier endo-lysosomal system Elsevier amyothoropic lateral sclerosis Stuck in traffic: an emerging theme in diseases of the nervous system |
| authorStr |
Neefjes, Jacques |
| ppnlink_with_tag_str_mv |
@@773@@(DE-627)ELV011304014 |
| format |
electronic Article |
| dewey-ones |
610 - Medicine & health 070 - News media, journalism & publishing 660 - Chemical engineering 333 - Economics of land & energy |
| delete_txt_mv |
keep |
| author_role |
aut |
| collection |
elsevier |
| remote_str |
true |
| illustrated |
Not Illustrated |
| topic_title |
610 610 DE-600 070 VZ 660 VZ 333.7 610 VZ 43.12 bkl 43.13 bkl 44.13 bkl Stuck in traffic: an emerging theme in diseases of the nervous system protein trafficking Elsevier Parkinson's disease Elsevier hereditary spastic paraplegia Elsevier neurological disease Elsevier Charcot-Marie-Tooth disease Elsevier Alzheimer's disease Elsevier endo-lysosomal system Elsevier amyothoropic lateral sclerosis Elsevier |
| topic |
ddc 610 ddc 070 ddc 660 ddc 333.7 bkl 43.12 bkl 43.13 bkl 44.13 Elsevier protein trafficking Elsevier Parkinson's disease Elsevier hereditary spastic paraplegia Elsevier neurological disease Elsevier Charcot-Marie-Tooth disease Elsevier Alzheimer's disease Elsevier endo-lysosomal system Elsevier amyothoropic lateral sclerosis |
| topic_unstemmed |
ddc 610 ddc 070 ddc 660 ddc 333.7 bkl 43.12 bkl 43.13 bkl 44.13 Elsevier protein trafficking Elsevier Parkinson's disease Elsevier hereditary spastic paraplegia Elsevier neurological disease Elsevier Charcot-Marie-Tooth disease Elsevier Alzheimer's disease Elsevier endo-lysosomal system Elsevier amyothoropic lateral sclerosis |
| topic_browse |
ddc 610 ddc 070 ddc 660 ddc 333.7 bkl 43.12 bkl 43.13 bkl 44.13 Elsevier protein trafficking Elsevier Parkinson's disease Elsevier hereditary spastic paraplegia Elsevier neurological disease Elsevier Charcot-Marie-Tooth disease Elsevier Alzheimer's disease Elsevier endo-lysosomal system Elsevier amyothoropic lateral sclerosis |
| format_facet |
Elektronische Aufsätze Aufsätze Elektronische Ressource |
| format_main_str_mv |
Text Zeitschrift/Artikel |
| carriertype_str_mv |
zu |
| author2_variant |
d k r v dkr dkrv |
| hierarchy_parent_title |
Ultimate nanopatterning of Si substrate using filtered liquid metal alloy ion source-focused ion beam |
| hierarchy_parent_id |
ELV011304014 |
| dewey-tens |
610 - Medicine & health 070 - News media, journalism & publishing 660 - Chemical engineering 330 - Economics |
| hierarchy_top_title |
Ultimate nanopatterning of Si substrate using filtered liquid metal alloy ion source-focused ion beam |
| isfreeaccess_txt |
false |
| familylinks_str_mv |
(DE-627)ELV011304014 |
| title |
Stuck in traffic: an emerging theme in diseases of the nervous system |
| ctrlnum |
(DE-627)ELV039233626 (ELSEVIER)S0166-2236(13)00228-2 |
| title_full |
Stuck in traffic: an emerging theme in diseases of the nervous system |
| author_sort |
Neefjes, Jacques |
| journal |
Ultimate nanopatterning of Si substrate using filtered liquid metal alloy ion source-focused ion beam |
| journalStr |
Ultimate nanopatterning of Si substrate using filtered liquid metal alloy ion source-focused ion beam |
| lang_code |
eng |
| isOA_bool |
false |
| dewey-hundreds |
600 - Technology 000 - Computer science, information & general works 300 - Social sciences |
| recordtype |
marc |
| publishDateSort |
2014 |
| contenttype_str_mv |
zzz |
| container_start_page |
66 |
| author_browse |
Neefjes, Jacques |
| container_volume |
37 |
| physical |
11 |
| class |
610 610 DE-600 070 VZ 660 VZ 333.7 610 VZ 43.12 bkl 43.13 bkl 44.13 bkl |
| format_se |
Elektronische Aufsätze |
| author-letter |
Neefjes, Jacques |
| doi_str_mv |
10.1016/j.tins.2013.11.006 |
| dewey-full |
610 070 660 333.7 |
| title_sort |
stuck in traffic: an emerging theme in diseases of the nervous system |
| title_auth |
Stuck in traffic: an emerging theme in diseases of the nervous system |
| abstract |
• The DNA sequencing revolution has revealed many new mutations in neurological diseases. • Many of these mutations affect proteins controlling endosomal/lysosomal transport. • A limited number of common cell-biological pathways are implicated in many cases. • Other proteins in these pathways are also predicted to yield neurological diseases. • Druggable nodes in these pathways may be defined for new/individualized treatments. |
| abstractGer |
• The DNA sequencing revolution has revealed many new mutations in neurological diseases. • Many of these mutations affect proteins controlling endosomal/lysosomal transport. • A limited number of common cell-biological pathways are implicated in many cases. • Other proteins in these pathways are also predicted to yield neurological diseases. • Druggable nodes in these pathways may be defined for new/individualized treatments. |
| abstract_unstemmed |
• The DNA sequencing revolution has revealed many new mutations in neurological diseases. • Many of these mutations affect proteins controlling endosomal/lysosomal transport. • A limited number of common cell-biological pathways are implicated in many cases. • Other proteins in these pathways are also predicted to yield neurological diseases. • Druggable nodes in these pathways may be defined for new/individualized treatments. |
| collection_details |
GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA SSG-OPC-GGO GBV_ILN_21 GBV_ILN_22 GBV_ILN_40 GBV_ILN_70 GBV_ILN_110 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2015 GBV_ILN_2021 GBV_ILN_2031 GBV_ILN_2032 GBV_ILN_2356 GBV_ILN_2523 |
| container_issue |
2 |
| title_short |
Stuck in traffic: an emerging theme in diseases of the nervous system |
| url |
https://doi.org/10.1016/j.tins.2013.11.006 |
| remote_bool |
true |
| author2 |
van der Kant, Rik |
| author2Str |
van der Kant, Rik |
| ppnlink |
ELV011304014 |
| mediatype_str_mv |
z |
| isOA_txt |
false |
| hochschulschrift_bool |
false |
| author2_role |
oth |
| doi_str |
10.1016/j.tins.2013.11.006 |
| up_date |
2024-07-06T20:06:54.577Z |
| _version_ |
1803861533211492352 |
| fullrecord_marcxml |
<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">ELV039233626</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230624055533.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">180603s2014 xx |||||o 00| ||eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1016/j.tins.2013.11.006</subfield><subfield code="2">doi</subfield></datafield><datafield tag="028" ind1="5" ind2="2"><subfield code="a">GBVA2014005000021.pica</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)ELV039233626</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(ELSEVIER)S0166-2236(13)00228-2</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="082" ind1="0" ind2=" "><subfield code="a">610</subfield></datafield><datafield tag="082" ind1="0" ind2="4"><subfield code="a">610</subfield><subfield code="q">DE-600</subfield></datafield><datafield tag="082" ind1="0" ind2="4"><subfield code="a">070</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="082" ind1="0" ind2="4"><subfield code="a">660</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="082" ind1="0" ind2="4"><subfield code="a">333.7</subfield><subfield code="a">610</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">43.12</subfield><subfield code="2">bkl</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">43.13</subfield><subfield code="2">bkl</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">44.13</subfield><subfield code="2">bkl</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Neefjes, Jacques</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Stuck in traffic: an emerging theme in diseases of the nervous system</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2014</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">11</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zzz</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">z</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zu</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">• The DNA sequencing revolution has revealed many new mutations in neurological diseases. • Many of these mutations affect proteins controlling endosomal/lysosomal transport. • A limited number of common cell-biological pathways are implicated in many cases. • Other proteins in these pathways are also predicted to yield neurological diseases. • Druggable nodes in these pathways may be defined for new/individualized treatments.</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">protein trafficking</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Parkinson's disease</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">hereditary spastic paraplegia</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">neurological disease</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Charcot-Marie-Tooth disease</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Alzheimer's disease</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">endo-lysosomal system</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">amyothoropic lateral sclerosis</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">van der Kant, Rik</subfield><subfield code="4">oth</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">Enthalten in</subfield><subfield code="n">Elsevier Science</subfield><subfield code="a">Benkouider, A. ELSEVIER</subfield><subfield code="t">Ultimate nanopatterning of Si substrate using filtered liquid metal alloy ion source-focused ion beam</subfield><subfield code="d">2013</subfield><subfield code="d">TINS</subfield><subfield code="g">Amsterdam [u.a.]</subfield><subfield code="w">(DE-627)ELV011304014</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:37</subfield><subfield code="g">year:2014</subfield><subfield code="g">number:2</subfield><subfield code="g">pages:66-76</subfield><subfield code="g">extent:11</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://doi.org/10.1016/j.tins.2013.11.006</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_U</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ELV</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SYSFLAG_U</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SSG-OLC-PHA</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SSG-OPC-GGO</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_21</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_22</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_40</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_70</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_110</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2004</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2005</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2009</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2015</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2021</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2031</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2032</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2356</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2523</subfield></datafield><datafield tag="936" ind1="b" ind2="k"><subfield code="a">43.12</subfield><subfield code="j">Umweltchemie</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="936" ind1="b" ind2="k"><subfield code="a">43.13</subfield><subfield code="j">Umwelttoxikologie</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="936" ind1="b" ind2="k"><subfield code="a">44.13</subfield><subfield code="j">Medizinische Ökologie</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">37</subfield><subfield code="j">2014</subfield><subfield code="e">2</subfield><subfield code="h">66-76</subfield><subfield code="g">11</subfield></datafield><datafield tag="953" ind1=" " ind2=" "><subfield code="2">045F</subfield><subfield code="a">610</subfield></datafield></record></collection>
|
| score |
7.400199 |