Identification of novel cyclic nucleotide binding proteins in Trypanosoma cruzi
Highlights • 27 putative proteins with predicted CBDs were in silico identified. • Studied candidates harbour conserved sequence motifs present in the CBD superfamily. • Homology-based structure modelling shown T. cruzi's CBDs could well accommodate cAMP. • TcCLB.508523.80 was biochemically val...
Ausführliche Beschreibung
Autor*in: |
Jäger, Adriana V. [verfasserIn] |
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E-Artikel |
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Sprache: |
Englisch |
Erschienen: |
2014 |
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Umfang: |
9 |
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Übergeordnetes Werk: |
Enthalten in: Novel heteroleptic iridium(III) complexes with a 2-(1H-pyrazol-5-yl)pyridine derivative containing a carbazole group as ancillary ligand: Synthesis and application for polymer light-emitting diodes - Tang, Huaijun ELSEVIER, 2014, Amsterdam |
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Übergeordnetes Werk: |
volume:198 ; year:2014 ; number:2 ; pages:104-112 ; extent:9 |
Links: |
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DOI / URN: |
10.1016/j.molbiopara.2015.02.002 |
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ELV039241009 |
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10.1016/j.molbiopara.2015.02.002 doi GBVA2014005000026.pica (DE-627)ELV039241009 (ELSEVIER)S0166-6851(15)00008-0 DE-627 ger DE-627 rakwb eng 590 540 610 590 DE-600 540 DE-600 610 DE-600 540 VZ 610 VZ 44.85 bkl Jäger, Adriana V. verfasserin aut Identification of novel cyclic nucleotide binding proteins in Trypanosoma cruzi 2014 9 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Highlights • 27 putative proteins with predicted CBDs were in silico identified. • Studied candidates harbour conserved sequence motifs present in the CBD superfamily. • Homology-based structure modelling shown T. cruzi's CBDs could well accommodate cAMP. • TcCLB.508523.80 was biochemically validated as bona fide cAMP-binding protein. cAMP signalling Elsevier Trypanosoma cruzi Elsevier cAMP binding proteins Elsevier cAMP novel effectors Elsevier De Gaudenzi, Javier G. oth Mild, Jesica G. oth Cormack, Bárbara Mc oth Pantano, Sergio oth Altschuler, Daniel L. oth Edreira, Martin M. oth Enthalten in Elsevier Tang, Huaijun ELSEVIER Novel heteroleptic iridium(III) complexes with a 2-(1H-pyrazol-5-yl)pyridine derivative containing a carbazole group as ancillary ligand: Synthesis and application for polymer light-emitting diodes 2014 Amsterdam (DE-627)ELV017571006 volume:198 year:2014 number:2 pages:104-112 extent:9 https://doi.org/10.1016/j.molbiopara.2015.02.002 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA GBV_ILN_23 GBV_ILN_70 44.85 Kardiologie Angiologie VZ AR 198 2014 2 104-112 9 045F 590 |
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10.1016/j.molbiopara.2015.02.002 doi GBVA2014005000026.pica (DE-627)ELV039241009 (ELSEVIER)S0166-6851(15)00008-0 DE-627 ger DE-627 rakwb eng 590 540 610 590 DE-600 540 DE-600 610 DE-600 540 VZ 610 VZ 44.85 bkl Jäger, Adriana V. verfasserin aut Identification of novel cyclic nucleotide binding proteins in Trypanosoma cruzi 2014 9 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Highlights • 27 putative proteins with predicted CBDs were in silico identified. • Studied candidates harbour conserved sequence motifs present in the CBD superfamily. • Homology-based structure modelling shown T. cruzi's CBDs could well accommodate cAMP. • TcCLB.508523.80 was biochemically validated as bona fide cAMP-binding protein. cAMP signalling Elsevier Trypanosoma cruzi Elsevier cAMP binding proteins Elsevier cAMP novel effectors Elsevier De Gaudenzi, Javier G. oth Mild, Jesica G. oth Cormack, Bárbara Mc oth Pantano, Sergio oth Altschuler, Daniel L. oth Edreira, Martin M. oth Enthalten in Elsevier Tang, Huaijun ELSEVIER Novel heteroleptic iridium(III) complexes with a 2-(1H-pyrazol-5-yl)pyridine derivative containing a carbazole group as ancillary ligand: Synthesis and application for polymer light-emitting diodes 2014 Amsterdam (DE-627)ELV017571006 volume:198 year:2014 number:2 pages:104-112 extent:9 https://doi.org/10.1016/j.molbiopara.2015.02.002 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA GBV_ILN_23 GBV_ILN_70 44.85 Kardiologie Angiologie VZ AR 198 2014 2 104-112 9 045F 590 |
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10.1016/j.molbiopara.2015.02.002 doi GBVA2014005000026.pica (DE-627)ELV039241009 (ELSEVIER)S0166-6851(15)00008-0 DE-627 ger DE-627 rakwb eng 590 540 610 590 DE-600 540 DE-600 610 DE-600 540 VZ 610 VZ 44.85 bkl Jäger, Adriana V. verfasserin aut Identification of novel cyclic nucleotide binding proteins in Trypanosoma cruzi 2014 9 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Highlights • 27 putative proteins with predicted CBDs were in silico identified. • Studied candidates harbour conserved sequence motifs present in the CBD superfamily. • Homology-based structure modelling shown T. cruzi's CBDs could well accommodate cAMP. • TcCLB.508523.80 was biochemically validated as bona fide cAMP-binding protein. cAMP signalling Elsevier Trypanosoma cruzi Elsevier cAMP binding proteins Elsevier cAMP novel effectors Elsevier De Gaudenzi, Javier G. oth Mild, Jesica G. oth Cormack, Bárbara Mc oth Pantano, Sergio oth Altschuler, Daniel L. oth Edreira, Martin M. oth Enthalten in Elsevier Tang, Huaijun ELSEVIER Novel heteroleptic iridium(III) complexes with a 2-(1H-pyrazol-5-yl)pyridine derivative containing a carbazole group as ancillary ligand: Synthesis and application for polymer light-emitting diodes 2014 Amsterdam (DE-627)ELV017571006 volume:198 year:2014 number:2 pages:104-112 extent:9 https://doi.org/10.1016/j.molbiopara.2015.02.002 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA GBV_ILN_23 GBV_ILN_70 44.85 Kardiologie Angiologie VZ AR 198 2014 2 104-112 9 045F 590 |
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10.1016/j.molbiopara.2015.02.002 doi GBVA2014005000026.pica (DE-627)ELV039241009 (ELSEVIER)S0166-6851(15)00008-0 DE-627 ger DE-627 rakwb eng 590 540 610 590 DE-600 540 DE-600 610 DE-600 540 VZ 610 VZ 44.85 bkl Jäger, Adriana V. verfasserin aut Identification of novel cyclic nucleotide binding proteins in Trypanosoma cruzi 2014 9 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Highlights • 27 putative proteins with predicted CBDs were in silico identified. • Studied candidates harbour conserved sequence motifs present in the CBD superfamily. • Homology-based structure modelling shown T. cruzi's CBDs could well accommodate cAMP. • TcCLB.508523.80 was biochemically validated as bona fide cAMP-binding protein. cAMP signalling Elsevier Trypanosoma cruzi Elsevier cAMP binding proteins Elsevier cAMP novel effectors Elsevier De Gaudenzi, Javier G. oth Mild, Jesica G. oth Cormack, Bárbara Mc oth Pantano, Sergio oth Altschuler, Daniel L. oth Edreira, Martin M. oth Enthalten in Elsevier Tang, Huaijun ELSEVIER Novel heteroleptic iridium(III) complexes with a 2-(1H-pyrazol-5-yl)pyridine derivative containing a carbazole group as ancillary ligand: Synthesis and application for polymer light-emitting diodes 2014 Amsterdam (DE-627)ELV017571006 volume:198 year:2014 number:2 pages:104-112 extent:9 https://doi.org/10.1016/j.molbiopara.2015.02.002 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA GBV_ILN_23 GBV_ILN_70 44.85 Kardiologie Angiologie VZ AR 198 2014 2 104-112 9 045F 590 |
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Identification of novel cyclic nucleotide binding proteins in Trypanosoma cruzi |
abstract |
Highlights • 27 putative proteins with predicted CBDs were in silico identified. • Studied candidates harbour conserved sequence motifs present in the CBD superfamily. • Homology-based structure modelling shown T. cruzi's CBDs could well accommodate cAMP. • TcCLB.508523.80 was biochemically validated as bona fide cAMP-binding protein. |
abstractGer |
Highlights • 27 putative proteins with predicted CBDs were in silico identified. • Studied candidates harbour conserved sequence motifs present in the CBD superfamily. • Homology-based structure modelling shown T. cruzi's CBDs could well accommodate cAMP. • TcCLB.508523.80 was biochemically validated as bona fide cAMP-binding protein. |
abstract_unstemmed |
Highlights • 27 putative proteins with predicted CBDs were in silico identified. • Studied candidates harbour conserved sequence motifs present in the CBD superfamily. • Homology-based structure modelling shown T. cruzi's CBDs could well accommodate cAMP. • TcCLB.508523.80 was biochemically validated as bona fide cAMP-binding protein. |
collection_details |
GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA GBV_ILN_23 GBV_ILN_70 |
container_issue |
2 |
title_short |
Identification of novel cyclic nucleotide binding proteins in Trypanosoma cruzi |
url |
https://doi.org/10.1016/j.molbiopara.2015.02.002 |
remote_bool |
true |
author2 |
De Gaudenzi, Javier G. Mild, Jesica G. Cormack, Bárbara Mc Pantano, Sergio Altschuler, Daniel L. Edreira, Martin M. |
author2Str |
De Gaudenzi, Javier G. Mild, Jesica G. Cormack, Bárbara Mc Pantano, Sergio Altschuler, Daniel L. Edreira, Martin M. |
ppnlink |
ELV017571006 |
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author2_role |
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doi_str |
10.1016/j.molbiopara.2015.02.002 |
up_date |
2024-07-06T20:08:07.323Z |
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1803861609492250624 |
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7.40075 |