Functional binding assays for estimation of the intrinsic efficacy of ligands at the 5-HT1A receptor: Application for screening drug candidates
Determination of the intrinsic efficacy of ligands at the 5-HT1A receptor is important for selecting drug candidates, e.g. in the case of schizophrenia where partial agonism is a favorable property shared by different atypical antipsychotics.
Gespeichert in:
| Autor*in: |
Noël, François [verfasserIn] |
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E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2014 |
|---|
| Umfang: |
7 |
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| Übergeordnetes Werk: |
Enthalten in: Differential roles of Sirt1 in HIF-1α and HIF-2α mediated hypoxic responses - Yoon, Haejin ELSEVIER, 2014, New York, NY [u.a.] |
|---|---|
| Übergeordnetes Werk: |
volume:70 ; year:2014 ; number:1 ; pages:12-18 ; extent:7 |
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10.1016/j.vascn.2014.03.002 |
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Determination of the intrinsic efficacy of ligands at the 5-HT1A receptor is important for selecting drug candidates, e.g. in the case of schizophrenia where partial agonism is a favorable property shared by different atypical antipsychotics. |
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