Unmasking immune sensing of retroviruses: Interplay between innate sensors and host effectors

• Host restriction and retroviral DNA sensing converge at different levels to mediate innate immunity. • Host factors Trex1 and SAMHD1 control the amount of retroviral DNA available for immune sensing. • DNA sensing by IFI16 and cGAS not only leads to antiviral responses but also triggers cell death...
Ausführliche Beschreibung

Gespeichert in:

Autor*in:	van Montfoort, Nadine [verfasserIn] Olagnier, David Hiscott, John

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2014

Schlagwörter:	dNTPase RNA TRAF TRIM MMTV CCCR5 RIG-I DDX41 AP-1 NF-κB PRR TBK1 MLV APOBEC HTLV-1 Mo-DC HBV ssDNA IL tRNA MEF AIM2 SLFN11 AZT IRF dsDNA HIV-1 SIV RT RTI CypA dNTP CXCR4 mRNA SAMHD1 IFN IFI16 cGAS NLRP3 TLR ISG CPSF6 DNA-PK STAT1 TREX1 gp DAI Myd88 pDC cGAMP DNA CDK1 EIAV STING RNase H DC

Umfang:	12

Übergeordnetes Werk:	Enthalten in: Decisional balance, self-leadership, self-efficacy, planning, and stages of change in adopting exercise behaviors in patients with stomach cancer: A cross-sectional study - Lee, Myung Kyung ELSEVIER, 2021, Amsterdam [u.a.]
Übergeordnetes Werk:	volume:25 ; year:2014 ; number:6 ; pages:657-668 ; extent:12

Links:	Volltext

DOI / URN:	10.1016/j.cytogfr.2014.08.006

Katalog-ID:	ELV039504018

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spelling	10.1016/j.cytogfr.2014.08.006 doi GBVA2014019000009.pica (DE-627)ELV039504018 (ELSEVIER)S1359-6101(14)00089-6 DE-627 ger DE-627 rakwb eng 610 610 DE-600 610 VZ 44.81 bkl 44.63 bkl van Montfoort, Nadine verfasserin aut Unmasking immune sensing of retroviruses: Interplay between innate sensors and host effectors 2014 12 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier • Host restriction and retroviral DNA sensing converge at different levels to mediate innate immunity. • Host factors Trex1 and SAMHD1 control the amount of retroviral DNA available for immune sensing. • DNA sensing by IFI16 and cGAS not only leads to antiviral responses but also triggers cell death pathways. dNTPase Elsevier RNA Elsevier TRAF Elsevier TRIM Elsevier MMTV Elsevier CCCR5 Elsevier RIG-I Elsevier DDX41 Elsevier AP-1 Elsevier NF-κB Elsevier PRR Elsevier TBK1 Elsevier MLV Elsevier APOBEC Elsevier HTLV-1 Elsevier Mo-DC Elsevier HBV Elsevier ssDNA Elsevier IL Elsevier tRNA Elsevier MEF Elsevier AIM2 Elsevier SLFN11 Elsevier AZT Elsevier IRF Elsevier dsDNA Elsevier HIV-1 Elsevier SIV Elsevier RT Elsevier RTI Elsevier CypA Elsevier dNTP Elsevier CXCR4 Elsevier mRNA Elsevier SAMHD1 Elsevier IFN Elsevier IFI16 Elsevier cGAS Elsevier NLRP3 Elsevier TLR Elsevier ISG Elsevier CPSF6 Elsevier DNA-PK Elsevier STAT1 Elsevier TREX1 Elsevier gp Elsevier DAI Elsevier Myd88 Elsevier pDC Elsevier cGAMP Elsevier DNA Elsevier CDK1 Elsevier EIAV Elsevier STING Elsevier RNase H Elsevier DC Elsevier Olagnier, David oth Hiscott, John oth Enthalten in Elsevier Science Lee, Myung Kyung ELSEVIER Decisional balance, self-leadership, self-efficacy, planning, and stages of change in adopting exercise behaviors in patients with stomach cancer: A cross-sectional study 2021 Amsterdam [u.a.] (DE-627)ELV007431309 volume:25 year:2014 number:6 pages:657-668 extent:12 https://doi.org/10.1016/j.cytogfr.2014.08.006 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U 44.81 Onkologie VZ 44.63 Krankenpflege VZ AR 25 2014 6 657-668 12 045F 610
allfields_unstemmed	10.1016/j.cytogfr.2014.08.006 doi GBVA2014019000009.pica (DE-627)ELV039504018 (ELSEVIER)S1359-6101(14)00089-6 DE-627 ger DE-627 rakwb eng 610 610 DE-600 610 VZ 44.81 bkl 44.63 bkl van Montfoort, Nadine verfasserin aut Unmasking immune sensing of retroviruses: Interplay between innate sensors and host effectors 2014 12 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier • Host restriction and retroviral DNA sensing converge at different levels to mediate innate immunity. • Host factors Trex1 and SAMHD1 control the amount of retroviral DNA available for immune sensing. • DNA sensing by IFI16 and cGAS not only leads to antiviral responses but also triggers cell death pathways. dNTPase Elsevier RNA Elsevier TRAF Elsevier TRIM Elsevier MMTV Elsevier CCCR5 Elsevier RIG-I Elsevier DDX41 Elsevier AP-1 Elsevier NF-κB Elsevier PRR Elsevier TBK1 Elsevier MLV Elsevier APOBEC Elsevier HTLV-1 Elsevier Mo-DC Elsevier HBV Elsevier ssDNA Elsevier IL Elsevier tRNA Elsevier MEF Elsevier AIM2 Elsevier SLFN11 Elsevier AZT Elsevier IRF Elsevier dsDNA Elsevier HIV-1 Elsevier SIV Elsevier RT Elsevier RTI Elsevier CypA Elsevier dNTP Elsevier CXCR4 Elsevier mRNA Elsevier SAMHD1 Elsevier IFN Elsevier IFI16 Elsevier cGAS Elsevier NLRP3 Elsevier TLR Elsevier ISG Elsevier CPSF6 Elsevier DNA-PK Elsevier STAT1 Elsevier TREX1 Elsevier gp Elsevier DAI Elsevier Myd88 Elsevier pDC Elsevier cGAMP Elsevier DNA Elsevier CDK1 Elsevier EIAV Elsevier STING Elsevier RNase H Elsevier DC Elsevier Olagnier, David oth Hiscott, John oth Enthalten in Elsevier Science Lee, Myung Kyung ELSEVIER Decisional balance, self-leadership, self-efficacy, planning, and stages of change in adopting exercise behaviors in patients with stomach cancer: A cross-sectional study 2021 Amsterdam [u.a.] (DE-627)ELV007431309 volume:25 year:2014 number:6 pages:657-668 extent:12 https://doi.org/10.1016/j.cytogfr.2014.08.006 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U 44.81 Onkologie VZ 44.63 Krankenpflege VZ AR 25 2014 6 657-668 12 045F 610
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author	van Montfoort, Nadine
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topic_title	610 610 DE-600 610 VZ 44.81 bkl 44.63 bkl Unmasking immune sensing of retroviruses: Interplay between innate sensors and host effectors dNTPase Elsevier RNA Elsevier TRAF Elsevier TRIM Elsevier MMTV Elsevier CCCR5 Elsevier RIG-I Elsevier DDX41 Elsevier AP-1 Elsevier NF-κB Elsevier PRR Elsevier TBK1 Elsevier MLV Elsevier APOBEC Elsevier HTLV-1 Elsevier Mo-DC Elsevier HBV Elsevier ssDNA Elsevier IL Elsevier tRNA Elsevier MEF Elsevier AIM2 Elsevier SLFN11 Elsevier AZT Elsevier IRF Elsevier dsDNA Elsevier HIV-1 Elsevier SIV Elsevier RT Elsevier RTI Elsevier CypA Elsevier dNTP Elsevier CXCR4 Elsevier mRNA Elsevier SAMHD1 Elsevier IFN Elsevier IFI16 Elsevier cGAS Elsevier NLRP3 Elsevier TLR Elsevier ISG Elsevier CPSF6 Elsevier DNA-PK Elsevier STAT1 Elsevier TREX1 Elsevier gp Elsevier DAI Elsevier Myd88 Elsevier pDC Elsevier cGAMP Elsevier DNA Elsevier CDK1 Elsevier EIAV Elsevier STING Elsevier RNase H Elsevier DC Elsevier
topic	ddc 610 bkl 44.81 bkl 44.63 Elsevier dNTPase Elsevier RNA Elsevier TRAF Elsevier TRIM Elsevier MMTV Elsevier CCCR5 Elsevier RIG-I Elsevier DDX41 Elsevier AP-1 Elsevier NF-κB Elsevier PRR Elsevier TBK1 Elsevier MLV Elsevier APOBEC Elsevier HTLV-1 Elsevier Mo-DC Elsevier HBV Elsevier ssDNA Elsevier IL Elsevier tRNA Elsevier MEF Elsevier AIM2 Elsevier SLFN11 Elsevier AZT Elsevier IRF Elsevier dsDNA Elsevier HIV-1 Elsevier SIV Elsevier RT Elsevier RTI Elsevier CypA Elsevier dNTP Elsevier CXCR4 Elsevier mRNA Elsevier SAMHD1 Elsevier IFN Elsevier IFI16 Elsevier cGAS Elsevier NLRP3 Elsevier TLR Elsevier ISG Elsevier CPSF6 Elsevier DNA-PK Elsevier STAT1 Elsevier TREX1 Elsevier gp Elsevier DAI Elsevier Myd88 Elsevier pDC Elsevier cGAMP Elsevier DNA Elsevier CDK1 Elsevier EIAV Elsevier STING Elsevier RNase H Elsevier DC
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title	Unmasking immune sensing of retroviruses: Interplay between innate sensors and host effectors
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title_full	Unmasking immune sensing of retroviruses: Interplay between innate sensors and host effectors
author_sort	van Montfoort, Nadine
journal	Decisional balance, self-leadership, self-efficacy, planning, and stages of change in adopting exercise behaviors in patients with stomach cancer: A cross-sectional study
journalStr	Decisional balance, self-leadership, self-efficacy, planning, and stages of change in adopting exercise behaviors in patients with stomach cancer: A cross-sectional study
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title_sort	unmasking immune sensing of retroviruses: interplay between innate sensors and host effectors
title_auth	Unmasking immune sensing of retroviruses: Interplay between innate sensors and host effectors
abstract	• Host restriction and retroviral DNA sensing converge at different levels to mediate innate immunity. • Host factors Trex1 and SAMHD1 control the amount of retroviral DNA available for immune sensing. • DNA sensing by IFI16 and cGAS not only leads to antiviral responses but also triggers cell death pathways.
abstractGer	• Host restriction and retroviral DNA sensing converge at different levels to mediate innate immunity. • Host factors Trex1 and SAMHD1 control the amount of retroviral DNA available for immune sensing. • DNA sensing by IFI16 and cGAS not only leads to antiviral responses but also triggers cell death pathways.
abstract_unstemmed	• Host restriction and retroviral DNA sensing converge at different levels to mediate innate immunity. • Host factors Trex1 and SAMHD1 control the amount of retroviral DNA available for immune sensing. • DNA sensing by IFI16 and cGAS not only leads to antiviral responses but also triggers cell death pathways.
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title_short	Unmasking immune sensing of retroviruses: Interplay between innate sensors and host effectors
url	https://doi.org/10.1016/j.cytogfr.2014.08.006
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author2	Olagnier, David Hiscott, John
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up_date	2024-07-06T20:46:38.578Z
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