Ampelopsin induces apoptosis in HepG2 human hepatoma cell line through extrinsic and intrinsic pathways: Involvement of P38 and ERK
• Ampelopsin reduces cell viability and induces apoptosis in HepG2 cells. • Induction of apoptosis through both the extrinsic and intrinsic pathways. • Ampelopsin increases phosphor-P38 and phosphor-ERK MAPK proteins levels. • U0126 and SB203580 have opposite effects on ampelopsin induced apoptosis....
Ausführliche Beschreibung
Autor*in: |
Qi, Shimei [verfasserIn] |
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Format: |
E-Artikel |
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Sprache: |
Englisch |
Erschienen: |
2015 |
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Schlagwörter: |
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Umfang: |
8 |
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Übergeordnetes Werk: |
Enthalten in: Evaluation of the proposed reporting system of the European LeukemiaNet and recommendations for prognosis of acute myeloid leukemia - 2013transfer abstract, Amsterdam [u.a.] |
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Übergeordnetes Werk: |
volume:40 ; year:2015 ; number:3 ; pages:847-854 ; extent:8 |
Links: |
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DOI / URN: |
10.1016/j.etap.2015.09.015 |
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ELV03958058X |
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10.1016/j.etap.2015.09.015 |
dewey-full |
610 333.7 |
title_sort |
ampelopsin induces apoptosis in hepg2 human hepatoma cell line through extrinsic and intrinsic pathways: involvement of p38 and erk |
title_auth |
Ampelopsin induces apoptosis in HepG2 human hepatoma cell line through extrinsic and intrinsic pathways: Involvement of P38 and ERK |
abstract |
• Ampelopsin reduces cell viability and induces apoptosis in HepG2 cells. • Induction of apoptosis through both the extrinsic and intrinsic pathways. • Ampelopsin increases phosphor-P38 and phosphor-ERK MAPK proteins levels. • U0126 and SB203580 have opposite effects on ampelopsin induced apoptosis. • Ampelopsin downregulates COX-2 and iNOS in a ROS independent way. |
abstractGer |
• Ampelopsin reduces cell viability and induces apoptosis in HepG2 cells. • Induction of apoptosis through both the extrinsic and intrinsic pathways. • Ampelopsin increases phosphor-P38 and phosphor-ERK MAPK proteins levels. • U0126 and SB203580 have opposite effects on ampelopsin induced apoptosis. • Ampelopsin downregulates COX-2 and iNOS in a ROS independent way. |
abstract_unstemmed |
• Ampelopsin reduces cell viability and induces apoptosis in HepG2 cells. • Induction of apoptosis through both the extrinsic and intrinsic pathways. • Ampelopsin increases phosphor-P38 and phosphor-ERK MAPK proteins levels. • U0126 and SB203580 have opposite effects on ampelopsin induced apoptosis. • Ampelopsin downregulates COX-2 and iNOS in a ROS independent way. |
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container_issue |
3 |
title_short |
Ampelopsin induces apoptosis in HepG2 human hepatoma cell line through extrinsic and intrinsic pathways: Involvement of P38 and ERK |
url |
https://doi.org/10.1016/j.etap.2015.09.015 |
remote_bool |
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author2 |
Kou, Xianjuan Lv, Jun Qi, Zhilin Yan, Liang |
author2Str |
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doi_str |
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up_date |
2024-07-06T20:58:47.078Z |
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