Unlocking the steric gate of DNA polymerase η leads to increased genomic instability in Saccharomyces cerevisiae
• Increased base- but reduced sugar-specificity of F35A pol η on undamaged DNA. • Accurate incorporation of rA opposite thymine dimers by the F35A pol η mutant. • RNase H2-dependent UV-sensitivity of a rad1Δ rev3Δ rad30-F35A strain. • Unique spectra of spontaneous mutations in a rad1Δ rev3Δ rad30-F3...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Donigan, Katherine A. [verfasserIn] |
|---|
| Format: |
E-Artikel |
|---|---|
| Sprache: |
Englisch |
| Erschienen: |
2015 |
|---|
| Schlagwörter: |
|---|
| Umfang: |
12 |
|---|
| Übergeordnetes Werk: |
Enthalten in: Reply - Zhang, Lin ELSEVIER, 2022, Amsterdam [u.a.] |
|---|---|
| Übergeordnetes Werk: |
volume:35 ; year:2015 ; pages:1-12 ; extent:12 |
| Links: |
|---|
| DOI / URN: |
10.1016/j.dnarep.2015.07.002 |
|---|
| Katalog-ID: |
ELV03967052X |
|---|
| LEADER | 01000caa a22002652 4500 | ||
|---|---|---|---|
| 001 | ELV03967052X | ||
| 003 | DE-627 | ||
| 005 | 20230624063347.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 180603s2015 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1016/j.dnarep.2015.07.002 |2 doi | |
| 028 | 5 | 2 | |a GBVA2015007000004.pica |
| 035 | |a (DE-627)ELV03967052X | ||
| 035 | |a (ELSEVIER)S1568-7864(15)30025-2 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 082 | 0 | |a 570 | |
| 082 | 0 | 4 | |a 570 |q DE-600 |
| 082 | 0 | 4 | |a 610 |q VZ |
| 084 | |a 44.87 |2 bkl | ||
| 100 | 1 | |a Donigan, Katherine A. |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Unlocking the steric gate of DNA polymerase η leads to increased genomic instability in Saccharomyces cerevisiae |
| 264 | 1 | |c 2015 | |
| 300 | |a 12 | ||
| 336 | |a nicht spezifiziert |b zzz |2 rdacontent | ||
| 337 | |a nicht spezifiziert |b z |2 rdamedia | ||
| 338 | |a nicht spezifiziert |b zu |2 rdacarrier | ||
| 520 | |a • Increased base- but reduced sugar-specificity of F35A pol η on undamaged DNA. • Accurate incorporation of rA opposite thymine dimers by the F35A pol η mutant. • RNase H2-dependent UV-sensitivity of a rad1Δ rev3Δ rad30-F35A strain. • Unique spectra of spontaneous mutations in a rad1Δ rev3Δ rad30-F35A rnh201Δ strain. • Novel RER pathway targeted at polyribonucleotides uncovered by the mutagenic spectra. | ||
| 650 | 7 | |a NMP |2 Elsevier | |
| 650 | 7 | |a CFS |2 Elsevier | |
| 650 | 7 | |a dNMP |2 Elsevier | |
| 650 | 7 | |a CPDs |2 Elsevier | |
| 650 | 7 | |a dNTP |2 Elsevier | |
| 650 | 7 | |a TLS |2 Elsevier | |
| 650 | 7 | |a NTP |2 Elsevier | |
| 650 | 7 | |a pol |2 Elsevier | |
| 650 | 7 | |a RNase H2 |2 Elsevier | |
| 650 | 7 | |a RER |2 Elsevier | |
| 650 | 7 | |a rA |2 Elsevier | |
| 700 | 1 | |a Cerritelli, Susana M. |4 oth | |
| 700 | 1 | |a McDonald, John P. |4 oth | |
| 700 | 1 | |a Vaisman, Alexandra |4 oth | |
| 700 | 1 | |a Crouch, Robert J. |4 oth | |
| 700 | 1 | |a Woodgate, Roger |4 oth | |
| 773 | 0 | 8 | |i Enthalten in |n Elsevier Science |a Zhang, Lin ELSEVIER |t Reply |d 2022 |g Amsterdam [u.a.] |w (DE-627)ELV007873700 |
| 773 | 1 | 8 | |g volume:35 |g year:2015 |g pages:1-12 |g extent:12 |
| 856 | 4 | 0 | |u https://doi.org/10.1016/j.dnarep.2015.07.002 |3 Volltext |
| 912 | |a GBV_USEFLAG_U | ||
| 912 | |a GBV_ELV | ||
| 912 | |a SYSFLAG_U | ||
| 912 | |a SSG-OLC-PHA | ||
| 936 | b | k | |a 44.87 |j Gastroenterologie |q VZ |
| 951 | |a AR | ||
| 952 | |d 35 |j 2015 |h 1-12 |g 12 | ||
| 953 | |2 045F |a 570 | ||
| author_variant |
k a d ka kad |
|---|---|
| matchkey_str |
donigankatherineacerritellisusanammcdona:2015----:nokntetrcaefnplmrslasonraegnmcntblti |
| hierarchy_sort_str |
2015 |
| bklnumber |
44.87 |
| publishDate |
2015 |
| allfields |
10.1016/j.dnarep.2015.07.002 doi GBVA2015007000004.pica (DE-627)ELV03967052X (ELSEVIER)S1568-7864(15)30025-2 DE-627 ger DE-627 rakwb eng 570 570 DE-600 610 VZ 44.87 bkl Donigan, Katherine A. verfasserin aut Unlocking the steric gate of DNA polymerase η leads to increased genomic instability in Saccharomyces cerevisiae 2015 12 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier • Increased base- but reduced sugar-specificity of F35A pol η on undamaged DNA. • Accurate incorporation of rA opposite thymine dimers by the F35A pol η mutant. • RNase H2-dependent UV-sensitivity of a rad1Δ rev3Δ rad30-F35A strain. • Unique spectra of spontaneous mutations in a rad1Δ rev3Δ rad30-F35A rnh201Δ strain. • Novel RER pathway targeted at polyribonucleotides uncovered by the mutagenic spectra. NMP Elsevier CFS Elsevier dNMP Elsevier CPDs Elsevier dNTP Elsevier TLS Elsevier NTP Elsevier pol Elsevier RNase H2 Elsevier RER Elsevier rA Elsevier Cerritelli, Susana M. oth McDonald, John P. oth Vaisman, Alexandra oth Crouch, Robert J. oth Woodgate, Roger oth Enthalten in Elsevier Science Zhang, Lin ELSEVIER Reply 2022 Amsterdam [u.a.] (DE-627)ELV007873700 volume:35 year:2015 pages:1-12 extent:12 https://doi.org/10.1016/j.dnarep.2015.07.002 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 44.87 Gastroenterologie VZ AR 35 2015 1-12 12 045F 570 |
| spelling |
10.1016/j.dnarep.2015.07.002 doi GBVA2015007000004.pica (DE-627)ELV03967052X (ELSEVIER)S1568-7864(15)30025-2 DE-627 ger DE-627 rakwb eng 570 570 DE-600 610 VZ 44.87 bkl Donigan, Katherine A. verfasserin aut Unlocking the steric gate of DNA polymerase η leads to increased genomic instability in Saccharomyces cerevisiae 2015 12 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier • Increased base- but reduced sugar-specificity of F35A pol η on undamaged DNA. • Accurate incorporation of rA opposite thymine dimers by the F35A pol η mutant. • RNase H2-dependent UV-sensitivity of a rad1Δ rev3Δ rad30-F35A strain. • Unique spectra of spontaneous mutations in a rad1Δ rev3Δ rad30-F35A rnh201Δ strain. • Novel RER pathway targeted at polyribonucleotides uncovered by the mutagenic spectra. NMP Elsevier CFS Elsevier dNMP Elsevier CPDs Elsevier dNTP Elsevier TLS Elsevier NTP Elsevier pol Elsevier RNase H2 Elsevier RER Elsevier rA Elsevier Cerritelli, Susana M. oth McDonald, John P. oth Vaisman, Alexandra oth Crouch, Robert J. oth Woodgate, Roger oth Enthalten in Elsevier Science Zhang, Lin ELSEVIER Reply 2022 Amsterdam [u.a.] (DE-627)ELV007873700 volume:35 year:2015 pages:1-12 extent:12 https://doi.org/10.1016/j.dnarep.2015.07.002 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 44.87 Gastroenterologie VZ AR 35 2015 1-12 12 045F 570 |
| allfields_unstemmed |
10.1016/j.dnarep.2015.07.002 doi GBVA2015007000004.pica (DE-627)ELV03967052X (ELSEVIER)S1568-7864(15)30025-2 DE-627 ger DE-627 rakwb eng 570 570 DE-600 610 VZ 44.87 bkl Donigan, Katherine A. verfasserin aut Unlocking the steric gate of DNA polymerase η leads to increased genomic instability in Saccharomyces cerevisiae 2015 12 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier • Increased base- but reduced sugar-specificity of F35A pol η on undamaged DNA. • Accurate incorporation of rA opposite thymine dimers by the F35A pol η mutant. • RNase H2-dependent UV-sensitivity of a rad1Δ rev3Δ rad30-F35A strain. • Unique spectra of spontaneous mutations in a rad1Δ rev3Δ rad30-F35A rnh201Δ strain. • Novel RER pathway targeted at polyribonucleotides uncovered by the mutagenic spectra. NMP Elsevier CFS Elsevier dNMP Elsevier CPDs Elsevier dNTP Elsevier TLS Elsevier NTP Elsevier pol Elsevier RNase H2 Elsevier RER Elsevier rA Elsevier Cerritelli, Susana M. oth McDonald, John P. oth Vaisman, Alexandra oth Crouch, Robert J. oth Woodgate, Roger oth Enthalten in Elsevier Science Zhang, Lin ELSEVIER Reply 2022 Amsterdam [u.a.] (DE-627)ELV007873700 volume:35 year:2015 pages:1-12 extent:12 https://doi.org/10.1016/j.dnarep.2015.07.002 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 44.87 Gastroenterologie VZ AR 35 2015 1-12 12 045F 570 |
| allfieldsGer |
10.1016/j.dnarep.2015.07.002 doi GBVA2015007000004.pica (DE-627)ELV03967052X (ELSEVIER)S1568-7864(15)30025-2 DE-627 ger DE-627 rakwb eng 570 570 DE-600 610 VZ 44.87 bkl Donigan, Katherine A. verfasserin aut Unlocking the steric gate of DNA polymerase η leads to increased genomic instability in Saccharomyces cerevisiae 2015 12 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier • Increased base- but reduced sugar-specificity of F35A pol η on undamaged DNA. • Accurate incorporation of rA opposite thymine dimers by the F35A pol η mutant. • RNase H2-dependent UV-sensitivity of a rad1Δ rev3Δ rad30-F35A strain. • Unique spectra of spontaneous mutations in a rad1Δ rev3Δ rad30-F35A rnh201Δ strain. • Novel RER pathway targeted at polyribonucleotides uncovered by the mutagenic spectra. NMP Elsevier CFS Elsevier dNMP Elsevier CPDs Elsevier dNTP Elsevier TLS Elsevier NTP Elsevier pol Elsevier RNase H2 Elsevier RER Elsevier rA Elsevier Cerritelli, Susana M. oth McDonald, John P. oth Vaisman, Alexandra oth Crouch, Robert J. oth Woodgate, Roger oth Enthalten in Elsevier Science Zhang, Lin ELSEVIER Reply 2022 Amsterdam [u.a.] (DE-627)ELV007873700 volume:35 year:2015 pages:1-12 extent:12 https://doi.org/10.1016/j.dnarep.2015.07.002 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 44.87 Gastroenterologie VZ AR 35 2015 1-12 12 045F 570 |
| allfieldsSound |
10.1016/j.dnarep.2015.07.002 doi GBVA2015007000004.pica (DE-627)ELV03967052X (ELSEVIER)S1568-7864(15)30025-2 DE-627 ger DE-627 rakwb eng 570 570 DE-600 610 VZ 44.87 bkl Donigan, Katherine A. verfasserin aut Unlocking the steric gate of DNA polymerase η leads to increased genomic instability in Saccharomyces cerevisiae 2015 12 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier • Increased base- but reduced sugar-specificity of F35A pol η on undamaged DNA. • Accurate incorporation of rA opposite thymine dimers by the F35A pol η mutant. • RNase H2-dependent UV-sensitivity of a rad1Δ rev3Δ rad30-F35A strain. • Unique spectra of spontaneous mutations in a rad1Δ rev3Δ rad30-F35A rnh201Δ strain. • Novel RER pathway targeted at polyribonucleotides uncovered by the mutagenic spectra. NMP Elsevier CFS Elsevier dNMP Elsevier CPDs Elsevier dNTP Elsevier TLS Elsevier NTP Elsevier pol Elsevier RNase H2 Elsevier RER Elsevier rA Elsevier Cerritelli, Susana M. oth McDonald, John P. oth Vaisman, Alexandra oth Crouch, Robert J. oth Woodgate, Roger oth Enthalten in Elsevier Science Zhang, Lin ELSEVIER Reply 2022 Amsterdam [u.a.] (DE-627)ELV007873700 volume:35 year:2015 pages:1-12 extent:12 https://doi.org/10.1016/j.dnarep.2015.07.002 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 44.87 Gastroenterologie VZ AR 35 2015 1-12 12 045F 570 |
| language |
English |
| source |
Enthalten in Reply Amsterdam [u.a.] volume:35 year:2015 pages:1-12 extent:12 |
| sourceStr |
Enthalten in Reply Amsterdam [u.a.] volume:35 year:2015 pages:1-12 extent:12 |
| format_phy_str_mv |
Article |
| bklname |
Gastroenterologie |
| institution |
findex.gbv.de |
| topic_facet |
NMP CFS dNMP CPDs dNTP TLS NTP pol RNase H2 RER rA |
| dewey-raw |
570 |
| isfreeaccess_bool |
false |
| container_title |
Reply |
| authorswithroles_txt_mv |
Donigan, Katherine A. @@aut@@ Cerritelli, Susana M. @@oth@@ McDonald, John P. @@oth@@ Vaisman, Alexandra @@oth@@ Crouch, Robert J. @@oth@@ Woodgate, Roger @@oth@@ |
| publishDateDaySort_date |
2015-01-01T00:00:00Z |
| hierarchy_top_id |
ELV007873700 |
| dewey-sort |
3570 |
| id |
ELV03967052X |
| language_de |
englisch |
| fullrecord |
<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">ELV03967052X</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230624063347.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">180603s2015 xx |||||o 00| ||eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1016/j.dnarep.2015.07.002</subfield><subfield code="2">doi</subfield></datafield><datafield tag="028" ind1="5" ind2="2"><subfield code="a">GBVA2015007000004.pica</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)ELV03967052X</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(ELSEVIER)S1568-7864(15)30025-2</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="082" ind1="0" ind2=" "><subfield code="a">570</subfield></datafield><datafield tag="082" ind1="0" ind2="4"><subfield code="a">570</subfield><subfield code="q">DE-600</subfield></datafield><datafield tag="082" ind1="0" ind2="4"><subfield code="a">610</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">44.87</subfield><subfield code="2">bkl</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Donigan, Katherine A.</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Unlocking the steric gate of DNA polymerase η leads to increased genomic instability in Saccharomyces cerevisiae</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2015</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">12</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zzz</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">z</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zu</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">• Increased base- but reduced sugar-specificity of F35A pol η on undamaged DNA. • Accurate incorporation of rA opposite thymine dimers by the F35A pol η mutant. • RNase H2-dependent UV-sensitivity of a rad1Δ rev3Δ rad30-F35A strain. • Unique spectra of spontaneous mutations in a rad1Δ rev3Δ rad30-F35A rnh201Δ strain. • Novel RER pathway targeted at polyribonucleotides uncovered by the mutagenic spectra.</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">NMP</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">CFS</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">dNMP</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">CPDs</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">dNTP</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">TLS</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">NTP</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">pol</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">RNase H2</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">RER</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">rA</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Cerritelli, Susana M.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">McDonald, John P.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Vaisman, Alexandra</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Crouch, Robert J.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Woodgate, Roger</subfield><subfield code="4">oth</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">Enthalten in</subfield><subfield code="n">Elsevier Science</subfield><subfield code="a">Zhang, Lin ELSEVIER</subfield><subfield code="t">Reply</subfield><subfield code="d">2022</subfield><subfield code="g">Amsterdam [u.a.]</subfield><subfield code="w">(DE-627)ELV007873700</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:35</subfield><subfield code="g">year:2015</subfield><subfield code="g">pages:1-12</subfield><subfield code="g">extent:12</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://doi.org/10.1016/j.dnarep.2015.07.002</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_U</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ELV</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SYSFLAG_U</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SSG-OLC-PHA</subfield></datafield><datafield tag="936" ind1="b" ind2="k"><subfield code="a">44.87</subfield><subfield code="j">Gastroenterologie</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">35</subfield><subfield code="j">2015</subfield><subfield code="h">1-12</subfield><subfield code="g">12</subfield></datafield><datafield tag="953" ind1=" " ind2=" "><subfield code="2">045F</subfield><subfield code="a">570</subfield></datafield></record></collection>
|
| author |
Donigan, Katherine A. |
| spellingShingle |
Donigan, Katherine A. ddc 570 ddc 610 bkl 44.87 Elsevier NMP Elsevier CFS Elsevier dNMP Elsevier CPDs Elsevier dNTP Elsevier TLS Elsevier NTP Elsevier pol Elsevier RNase H2 Elsevier RER Elsevier rA Unlocking the steric gate of DNA polymerase η leads to increased genomic instability in Saccharomyces cerevisiae |
| authorStr |
Donigan, Katherine A. |
| ppnlink_with_tag_str_mv |
@@773@@(DE-627)ELV007873700 |
| format |
electronic Article |
| dewey-ones |
570 - Life sciences; biology 610 - Medicine & health |
| delete_txt_mv |
keep |
| author_role |
aut |
| collection |
elsevier |
| remote_str |
true |
| illustrated |
Not Illustrated |
| topic_title |
570 570 DE-600 610 VZ 44.87 bkl Unlocking the steric gate of DNA polymerase η leads to increased genomic instability in Saccharomyces cerevisiae NMP Elsevier CFS Elsevier dNMP Elsevier CPDs Elsevier dNTP Elsevier TLS Elsevier NTP Elsevier pol Elsevier RNase H2 Elsevier RER Elsevier rA Elsevier |
| topic |
ddc 570 ddc 610 bkl 44.87 Elsevier NMP Elsevier CFS Elsevier dNMP Elsevier CPDs Elsevier dNTP Elsevier TLS Elsevier NTP Elsevier pol Elsevier RNase H2 Elsevier RER Elsevier rA |
| topic_unstemmed |
ddc 570 ddc 610 bkl 44.87 Elsevier NMP Elsevier CFS Elsevier dNMP Elsevier CPDs Elsevier dNTP Elsevier TLS Elsevier NTP Elsevier pol Elsevier RNase H2 Elsevier RER Elsevier rA |
| topic_browse |
ddc 570 ddc 610 bkl 44.87 Elsevier NMP Elsevier CFS Elsevier dNMP Elsevier CPDs Elsevier dNTP Elsevier TLS Elsevier NTP Elsevier pol Elsevier RNase H2 Elsevier RER Elsevier rA |
| format_facet |
Elektronische Aufsätze Aufsätze Elektronische Ressource |
| format_main_str_mv |
Text Zeitschrift/Artikel |
| carriertype_str_mv |
zu |
| author2_variant |
s m c sm smc j p m jp jpm a v av r j c rj rjc r w rw |
| hierarchy_parent_title |
Reply |
| hierarchy_parent_id |
ELV007873700 |
| dewey-tens |
570 - Life sciences; biology 610 - Medicine & health |
| hierarchy_top_title |
Reply |
| isfreeaccess_txt |
false |
| familylinks_str_mv |
(DE-627)ELV007873700 |
| title |
Unlocking the steric gate of DNA polymerase η leads to increased genomic instability in Saccharomyces cerevisiae |
| ctrlnum |
(DE-627)ELV03967052X (ELSEVIER)S1568-7864(15)30025-2 |
| title_full |
Unlocking the steric gate of DNA polymerase η leads to increased genomic instability in Saccharomyces cerevisiae |
| author_sort |
Donigan, Katherine A. |
| journal |
Reply |
| journalStr |
Reply |
| lang_code |
eng |
| isOA_bool |
false |
| dewey-hundreds |
500 - Science 600 - Technology |
| recordtype |
marc |
| publishDateSort |
2015 |
| contenttype_str_mv |
zzz |
| container_start_page |
1 |
| author_browse |
Donigan, Katherine A. |
| container_volume |
35 |
| physical |
12 |
| class |
570 570 DE-600 610 VZ 44.87 bkl |
| format_se |
Elektronische Aufsätze |
| author-letter |
Donigan, Katherine A. |
| doi_str_mv |
10.1016/j.dnarep.2015.07.002 |
| dewey-full |
570 610 |
| title_sort |
unlocking the steric gate of dna polymerase η leads to increased genomic instability in saccharomyces cerevisiae |
| title_auth |
Unlocking the steric gate of DNA polymerase η leads to increased genomic instability in Saccharomyces cerevisiae |
| abstract |
• Increased base- but reduced sugar-specificity of F35A pol η on undamaged DNA. • Accurate incorporation of rA opposite thymine dimers by the F35A pol η mutant. • RNase H2-dependent UV-sensitivity of a rad1Δ rev3Δ rad30-F35A strain. • Unique spectra of spontaneous mutations in a rad1Δ rev3Δ rad30-F35A rnh201Δ strain. • Novel RER pathway targeted at polyribonucleotides uncovered by the mutagenic spectra. |
| abstractGer |
• Increased base- but reduced sugar-specificity of F35A pol η on undamaged DNA. • Accurate incorporation of rA opposite thymine dimers by the F35A pol η mutant. • RNase H2-dependent UV-sensitivity of a rad1Δ rev3Δ rad30-F35A strain. • Unique spectra of spontaneous mutations in a rad1Δ rev3Δ rad30-F35A rnh201Δ strain. • Novel RER pathway targeted at polyribonucleotides uncovered by the mutagenic spectra. |
| abstract_unstemmed |
• Increased base- but reduced sugar-specificity of F35A pol η on undamaged DNA. • Accurate incorporation of rA opposite thymine dimers by the F35A pol η mutant. • RNase H2-dependent UV-sensitivity of a rad1Δ rev3Δ rad30-F35A strain. • Unique spectra of spontaneous mutations in a rad1Δ rev3Δ rad30-F35A rnh201Δ strain. • Novel RER pathway targeted at polyribonucleotides uncovered by the mutagenic spectra. |
| collection_details |
GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA |
| title_short |
Unlocking the steric gate of DNA polymerase η leads to increased genomic instability in Saccharomyces cerevisiae |
| url |
https://doi.org/10.1016/j.dnarep.2015.07.002 |
| remote_bool |
true |
| author2 |
Cerritelli, Susana M. McDonald, John P. Vaisman, Alexandra Crouch, Robert J. Woodgate, Roger |
| author2Str |
Cerritelli, Susana M. McDonald, John P. Vaisman, Alexandra Crouch, Robert J. Woodgate, Roger |
| ppnlink |
ELV007873700 |
| mediatype_str_mv |
z |
| isOA_txt |
false |
| hochschulschrift_bool |
false |
| author2_role |
oth oth oth oth oth |
| doi_str |
10.1016/j.dnarep.2015.07.002 |
| up_date |
2024-07-06T21:12:14.428Z |
| _version_ |
1803865643474223104 |
| fullrecord_marcxml |
<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">ELV03967052X</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230624063347.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">180603s2015 xx |||||o 00| ||eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1016/j.dnarep.2015.07.002</subfield><subfield code="2">doi</subfield></datafield><datafield tag="028" ind1="5" ind2="2"><subfield code="a">GBVA2015007000004.pica</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)ELV03967052X</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(ELSEVIER)S1568-7864(15)30025-2</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="082" ind1="0" ind2=" "><subfield code="a">570</subfield></datafield><datafield tag="082" ind1="0" ind2="4"><subfield code="a">570</subfield><subfield code="q">DE-600</subfield></datafield><datafield tag="082" ind1="0" ind2="4"><subfield code="a">610</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">44.87</subfield><subfield code="2">bkl</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Donigan, Katherine A.</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Unlocking the steric gate of DNA polymerase η leads to increased genomic instability in Saccharomyces cerevisiae</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2015</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">12</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zzz</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">z</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zu</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">• Increased base- but reduced sugar-specificity of F35A pol η on undamaged DNA. • Accurate incorporation of rA opposite thymine dimers by the F35A pol η mutant. • RNase H2-dependent UV-sensitivity of a rad1Δ rev3Δ rad30-F35A strain. • Unique spectra of spontaneous mutations in a rad1Δ rev3Δ rad30-F35A rnh201Δ strain. • Novel RER pathway targeted at polyribonucleotides uncovered by the mutagenic spectra.</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">NMP</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">CFS</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">dNMP</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">CPDs</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">dNTP</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">TLS</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">NTP</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">pol</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">RNase H2</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">RER</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">rA</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Cerritelli, Susana M.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">McDonald, John P.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Vaisman, Alexandra</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Crouch, Robert J.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Woodgate, Roger</subfield><subfield code="4">oth</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">Enthalten in</subfield><subfield code="n">Elsevier Science</subfield><subfield code="a">Zhang, Lin ELSEVIER</subfield><subfield code="t">Reply</subfield><subfield code="d">2022</subfield><subfield code="g">Amsterdam [u.a.]</subfield><subfield code="w">(DE-627)ELV007873700</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:35</subfield><subfield code="g">year:2015</subfield><subfield code="g">pages:1-12</subfield><subfield code="g">extent:12</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://doi.org/10.1016/j.dnarep.2015.07.002</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_U</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ELV</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SYSFLAG_U</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SSG-OLC-PHA</subfield></datafield><datafield tag="936" ind1="b" ind2="k"><subfield code="a">44.87</subfield><subfield code="j">Gastroenterologie</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">35</subfield><subfield code="j">2015</subfield><subfield code="h">1-12</subfield><subfield code="g">12</subfield></datafield><datafield tag="953" ind1=" " ind2=" "><subfield code="2">045F</subfield><subfield code="a">570</subfield></datafield></record></collection>
|
| score |
7.399496 |