The sooner the better: innate immunity as a path toward the HIV cure
• Virus dissemination occurs rapidly after mucosal SIV infection. • Early innate host immune response after HIV/SIV infection dictates viral load at acute phase. • Specific Interferon signatures are associated to viral dissemination. • Inflammasome activation at early time-points inhibits intrinsic...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Tomalka, Jeffrey [verfasserIn] |
|---|
| Format: |
E-Artikel |
|---|---|
| Sprache: |
Englisch |
| Erschienen: |
2016 |
|---|
| Umfang: |
7 |
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| Übergeordnetes Werk: |
Enthalten in: Preparation of high internal phase Pickering emulsion by centrifugation for 3D printing and astaxanthin delivery - Song, Jia ELSEVIER, 2023, Amsterdam [u.a.] |
|---|---|
| Übergeordnetes Werk: |
volume:19 ; year:2016 ; pages:85-91 ; extent:7 |
| Links: |
|---|
| DOI / URN: |
10.1016/j.coviro.2016.07.003 |
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• Virus dissemination occurs rapidly after mucosal SIV infection. • Early innate host immune response after HIV/SIV infection dictates viral load at acute phase. • Specific Interferon signatures are associated to viral dissemination. • Inflammasome activation at early time-points inhibits intrinsic innate anti-viral responses and leads to virus dissemination and seeding. |
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• Virus dissemination occurs rapidly after mucosal SIV infection. • Early innate host immune response after HIV/SIV infection dictates viral load at acute phase. • Specific Interferon signatures are associated to viral dissemination. • Inflammasome activation at early time-points inhibits intrinsic innate anti-viral responses and leads to virus dissemination and seeding. |
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• Virus dissemination occurs rapidly after mucosal SIV infection. • Early innate host immune response after HIV/SIV infection dictates viral load at acute phase. • Specific Interferon signatures are associated to viral dissemination. • Inflammasome activation at early time-points inhibits intrinsic innate anti-viral responses and leads to virus dissemination and seeding. |
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