Seladoeflavones A–F, six novel flavonoids from Selaginella doederleinii
Six new flavonoids, seladoeflavones A–F (1–6), were isolated from the whole herbs of Selaginella doederleinii, together with one known flavonoid (7). Their structures including absolute configuration were characterized on the basis of extensive spectroscopic methods including NMR, HRMS, and electron...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Zou, ZhenXing [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2017transfer abstract |
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| Umfang: |
6 |
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| Übergeordnetes Werk: |
Enthalten in: MASE-EGTI: An agent-based simulator for environmental land change - Coelho, Cássio Giorgio Couto ELSEVIER, 2021, the journal of the study of medicinal plants, Amsterdam [u.a.] |
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| Übergeordnetes Werk: |
volume:116 ; year:2017 ; pages:66-71 ; extent:6 |
| Links: |
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| DOI / URN: |
10.1016/j.fitote.2016.11.014 |
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| 520 | |a Six new flavonoids, seladoeflavones A–F (1–6), were isolated from the whole herbs of Selaginella doederleinii, together with one known flavonoid (7). Their structures including absolute configuration were characterized on the basis of extensive spectroscopic methods including NMR, HRMS, and electronic circular dichroism (ECD). All compounds consist of an aryl substituent at the C-3′ position of naringenin or apigenin skeletons, and compounds 1 and 6 were identified as R configurations, which are uncommonly encountered in nature. A possible biosynthetic pathway was postulated. In addition, bioassay of the isolates revealed that 5–7 exhibited moderate cytotoxicity against three human cancer cell lines NCI-H460, A549, and K562 in vitro with IC50 values ranging from 8.17 to 18.66μM. | ||
| 520 | |a Six new flavonoids, seladoeflavones A–F (1–6), were isolated from the whole herbs of Selaginella doederleinii, together with one known flavonoid (7). Their structures including absolute configuration were characterized on the basis of extensive spectroscopic methods including NMR, HRMS, and electronic circular dichroism (ECD). All compounds consist of an aryl substituent at the C-3′ position of naringenin or apigenin skeletons, and compounds 1 and 6 were identified as R configurations, which are uncommonly encountered in nature. A possible biosynthetic pathway was postulated. In addition, bioassay of the isolates revealed that 5–7 exhibited moderate cytotoxicity against three human cancer cell lines NCI-H460, A549, and K562 in vitro with IC50 values ranging from 8.17 to 18.66μM. | ||
| 700 | 1 | |a Xu, KangPing |4 oth | |
| 700 | 1 | |a Xu, PingSheng |4 oth | |
| 700 | 1 | |a Li, XiaoMin |4 oth | |
| 700 | 1 | |a Cheng, Fei |4 oth | |
| 700 | 1 | |a Li, Jing |4 oth | |
| 700 | 1 | |a Yu, Xia |4 oth | |
| 700 | 1 | |a Cao, DongSheng |4 oth | |
| 700 | 1 | |a Li, Dan |4 oth | |
| 700 | 1 | |a Zeng, Wei |4 oth | |
| 700 | 1 | |a Zhang, GuoGang |4 oth | |
| 700 | 1 | |a Tan, GuiShan |4 oth | |
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10.1016/j.fitote.2016.11.014 doi GBVA2017011000019.pica (DE-627)ELV040454584 (ELSEVIER)S0367-326X(16)30545-7 DE-627 ger DE-627 rakwb eng 570 570 DE-600 690 004 VZ 43.03 bkl Zou, ZhenXing verfasserin aut Seladoeflavones A–F, six novel flavonoids from Selaginella doederleinii 2017transfer abstract 6 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Six new flavonoids, seladoeflavones A–F (1–6), were isolated from the whole herbs of Selaginella doederleinii, together with one known flavonoid (7). Their structures including absolute configuration were characterized on the basis of extensive spectroscopic methods including NMR, HRMS, and electronic circular dichroism (ECD). All compounds consist of an aryl substituent at the C-3′ position of naringenin or apigenin skeletons, and compounds 1 and 6 were identified as R configurations, which are uncommonly encountered in nature. A possible biosynthetic pathway was postulated. In addition, bioassay of the isolates revealed that 5–7 exhibited moderate cytotoxicity against three human cancer cell lines NCI-H460, A549, and K562 in vitro with IC50 values ranging from 8.17 to 18.66μM. Six new flavonoids, seladoeflavones A–F (1–6), were isolated from the whole herbs of Selaginella doederleinii, together with one known flavonoid (7). Their structures including absolute configuration were characterized on the basis of extensive spectroscopic methods including NMR, HRMS, and electronic circular dichroism (ECD). All compounds consist of an aryl substituent at the C-3′ position of naringenin or apigenin skeletons, and compounds 1 and 6 were identified as R configurations, which are uncommonly encountered in nature. A possible biosynthetic pathway was postulated. In addition, bioassay of the isolates revealed that 5–7 exhibited moderate cytotoxicity against three human cancer cell lines NCI-H460, A549, and K562 in vitro with IC50 values ranging from 8.17 to 18.66μM. Xu, KangPing oth Xu, PingSheng oth Li, XiaoMin oth Cheng, Fei oth Li, Jing oth Yu, Xia oth Cao, DongSheng oth Li, Dan oth Zeng, Wei oth Zhang, GuoGang oth Tan, GuiShan oth Enthalten in Elsevier Science Coelho, Cássio Giorgio Couto ELSEVIER MASE-EGTI: An agent-based simulator for environmental land change 2021 the journal of the study of medicinal plants Amsterdam [u.a.] (DE-627)ELV007030444 volume:116 year:2017 pages:66-71 extent:6 https://doi.org/10.1016/j.fitote.2016.11.014 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-UMW SSG-OLC-ARC SSG-OLC-TEC SSG-OLC-MAT SSG-OLC-FOR 43.03 Methoden der Umweltforschung und des Umweltschutzes VZ AR 116 2017 66-71 6 045F 570 |
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10.1016/j.fitote.2016.11.014 doi GBVA2017011000019.pica (DE-627)ELV040454584 (ELSEVIER)S0367-326X(16)30545-7 DE-627 ger DE-627 rakwb eng 570 570 DE-600 690 004 VZ 43.03 bkl Zou, ZhenXing verfasserin aut Seladoeflavones A–F, six novel flavonoids from Selaginella doederleinii 2017transfer abstract 6 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Six new flavonoids, seladoeflavones A–F (1–6), were isolated from the whole herbs of Selaginella doederleinii, together with one known flavonoid (7). Their structures including absolute configuration were characterized on the basis of extensive spectroscopic methods including NMR, HRMS, and electronic circular dichroism (ECD). All compounds consist of an aryl substituent at the C-3′ position of naringenin or apigenin skeletons, and compounds 1 and 6 were identified as R configurations, which are uncommonly encountered in nature. A possible biosynthetic pathway was postulated. In addition, bioassay of the isolates revealed that 5–7 exhibited moderate cytotoxicity against three human cancer cell lines NCI-H460, A549, and K562 in vitro with IC50 values ranging from 8.17 to 18.66μM. Six new flavonoids, seladoeflavones A–F (1–6), were isolated from the whole herbs of Selaginella doederleinii, together with one known flavonoid (7). Their structures including absolute configuration were characterized on the basis of extensive spectroscopic methods including NMR, HRMS, and electronic circular dichroism (ECD). All compounds consist of an aryl substituent at the C-3′ position of naringenin or apigenin skeletons, and compounds 1 and 6 were identified as R configurations, which are uncommonly encountered in nature. A possible biosynthetic pathway was postulated. In addition, bioassay of the isolates revealed that 5–7 exhibited moderate cytotoxicity against three human cancer cell lines NCI-H460, A549, and K562 in vitro with IC50 values ranging from 8.17 to 18.66μM. Xu, KangPing oth Xu, PingSheng oth Li, XiaoMin oth Cheng, Fei oth Li, Jing oth Yu, Xia oth Cao, DongSheng oth Li, Dan oth Zeng, Wei oth Zhang, GuoGang oth Tan, GuiShan oth Enthalten in Elsevier Science Coelho, Cássio Giorgio Couto ELSEVIER MASE-EGTI: An agent-based simulator for environmental land change 2021 the journal of the study of medicinal plants Amsterdam [u.a.] (DE-627)ELV007030444 volume:116 year:2017 pages:66-71 extent:6 https://doi.org/10.1016/j.fitote.2016.11.014 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-UMW SSG-OLC-ARC SSG-OLC-TEC SSG-OLC-MAT SSG-OLC-FOR 43.03 Methoden der Umweltforschung und des Umweltschutzes VZ AR 116 2017 66-71 6 045F 570 |
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10.1016/j.fitote.2016.11.014 doi GBVA2017011000019.pica (DE-627)ELV040454584 (ELSEVIER)S0367-326X(16)30545-7 DE-627 ger DE-627 rakwb eng 570 570 DE-600 690 004 VZ 43.03 bkl Zou, ZhenXing verfasserin aut Seladoeflavones A–F, six novel flavonoids from Selaginella doederleinii 2017transfer abstract 6 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Six new flavonoids, seladoeflavones A–F (1–6), were isolated from the whole herbs of Selaginella doederleinii, together with one known flavonoid (7). Their structures including absolute configuration were characterized on the basis of extensive spectroscopic methods including NMR, HRMS, and electronic circular dichroism (ECD). All compounds consist of an aryl substituent at the C-3′ position of naringenin or apigenin skeletons, and compounds 1 and 6 were identified as R configurations, which are uncommonly encountered in nature. A possible biosynthetic pathway was postulated. In addition, bioassay of the isolates revealed that 5–7 exhibited moderate cytotoxicity against three human cancer cell lines NCI-H460, A549, and K562 in vitro with IC50 values ranging from 8.17 to 18.66μM. Six new flavonoids, seladoeflavones A–F (1–6), were isolated from the whole herbs of Selaginella doederleinii, together with one known flavonoid (7). Their structures including absolute configuration were characterized on the basis of extensive spectroscopic methods including NMR, HRMS, and electronic circular dichroism (ECD). All compounds consist of an aryl substituent at the C-3′ position of naringenin or apigenin skeletons, and compounds 1 and 6 were identified as R configurations, which are uncommonly encountered in nature. A possible biosynthetic pathway was postulated. In addition, bioassay of the isolates revealed that 5–7 exhibited moderate cytotoxicity against three human cancer cell lines NCI-H460, A549, and K562 in vitro with IC50 values ranging from 8.17 to 18.66μM. Xu, KangPing oth Xu, PingSheng oth Li, XiaoMin oth Cheng, Fei oth Li, Jing oth Yu, Xia oth Cao, DongSheng oth Li, Dan oth Zeng, Wei oth Zhang, GuoGang oth Tan, GuiShan oth Enthalten in Elsevier Science Coelho, Cássio Giorgio Couto ELSEVIER MASE-EGTI: An agent-based simulator for environmental land change 2021 the journal of the study of medicinal plants Amsterdam [u.a.] (DE-627)ELV007030444 volume:116 year:2017 pages:66-71 extent:6 https://doi.org/10.1016/j.fitote.2016.11.014 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-UMW SSG-OLC-ARC SSG-OLC-TEC SSG-OLC-MAT SSG-OLC-FOR 43.03 Methoden der Umweltforschung und des Umweltschutzes VZ AR 116 2017 66-71 6 045F 570 |
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10.1016/j.fitote.2016.11.014 doi GBVA2017011000019.pica (DE-627)ELV040454584 (ELSEVIER)S0367-326X(16)30545-7 DE-627 ger DE-627 rakwb eng 570 570 DE-600 690 004 VZ 43.03 bkl Zou, ZhenXing verfasserin aut Seladoeflavones A–F, six novel flavonoids from Selaginella doederleinii 2017transfer abstract 6 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Six new flavonoids, seladoeflavones A–F (1–6), were isolated from the whole herbs of Selaginella doederleinii, together with one known flavonoid (7). Their structures including absolute configuration were characterized on the basis of extensive spectroscopic methods including NMR, HRMS, and electronic circular dichroism (ECD). All compounds consist of an aryl substituent at the C-3′ position of naringenin or apigenin skeletons, and compounds 1 and 6 were identified as R configurations, which are uncommonly encountered in nature. A possible biosynthetic pathway was postulated. In addition, bioassay of the isolates revealed that 5–7 exhibited moderate cytotoxicity against three human cancer cell lines NCI-H460, A549, and K562 in vitro with IC50 values ranging from 8.17 to 18.66μM. Six new flavonoids, seladoeflavones A–F (1–6), were isolated from the whole herbs of Selaginella doederleinii, together with one known flavonoid (7). Their structures including absolute configuration were characterized on the basis of extensive spectroscopic methods including NMR, HRMS, and electronic circular dichroism (ECD). All compounds consist of an aryl substituent at the C-3′ position of naringenin or apigenin skeletons, and compounds 1 and 6 were identified as R configurations, which are uncommonly encountered in nature. A possible biosynthetic pathway was postulated. In addition, bioassay of the isolates revealed that 5–7 exhibited moderate cytotoxicity against three human cancer cell lines NCI-H460, A549, and K562 in vitro with IC50 values ranging from 8.17 to 18.66μM. Xu, KangPing oth Xu, PingSheng oth Li, XiaoMin oth Cheng, Fei oth Li, Jing oth Yu, Xia oth Cao, DongSheng oth Li, Dan oth Zeng, Wei oth Zhang, GuoGang oth Tan, GuiShan oth Enthalten in Elsevier Science Coelho, Cássio Giorgio Couto ELSEVIER MASE-EGTI: An agent-based simulator for environmental land change 2021 the journal of the study of medicinal plants Amsterdam [u.a.] (DE-627)ELV007030444 volume:116 year:2017 pages:66-71 extent:6 https://doi.org/10.1016/j.fitote.2016.11.014 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-UMW SSG-OLC-ARC SSG-OLC-TEC SSG-OLC-MAT SSG-OLC-FOR 43.03 Methoden der Umweltforschung und des Umweltschutzes VZ AR 116 2017 66-71 6 045F 570 |
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10.1016/j.fitote.2016.11.014 doi GBVA2017011000019.pica (DE-627)ELV040454584 (ELSEVIER)S0367-326X(16)30545-7 DE-627 ger DE-627 rakwb eng 570 570 DE-600 690 004 VZ 43.03 bkl Zou, ZhenXing verfasserin aut Seladoeflavones A–F, six novel flavonoids from Selaginella doederleinii 2017transfer abstract 6 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Six new flavonoids, seladoeflavones A–F (1–6), were isolated from the whole herbs of Selaginella doederleinii, together with one known flavonoid (7). Their structures including absolute configuration were characterized on the basis of extensive spectroscopic methods including NMR, HRMS, and electronic circular dichroism (ECD). All compounds consist of an aryl substituent at the C-3′ position of naringenin or apigenin skeletons, and compounds 1 and 6 were identified as R configurations, which are uncommonly encountered in nature. A possible biosynthetic pathway was postulated. In addition, bioassay of the isolates revealed that 5–7 exhibited moderate cytotoxicity against three human cancer cell lines NCI-H460, A549, and K562 in vitro with IC50 values ranging from 8.17 to 18.66μM. Six new flavonoids, seladoeflavones A–F (1–6), were isolated from the whole herbs of Selaginella doederleinii, together with one known flavonoid (7). Their structures including absolute configuration were characterized on the basis of extensive spectroscopic methods including NMR, HRMS, and electronic circular dichroism (ECD). All compounds consist of an aryl substituent at the C-3′ position of naringenin or apigenin skeletons, and compounds 1 and 6 were identified as R configurations, which are uncommonly encountered in nature. A possible biosynthetic pathway was postulated. In addition, bioassay of the isolates revealed that 5–7 exhibited moderate cytotoxicity against three human cancer cell lines NCI-H460, A549, and K562 in vitro with IC50 values ranging from 8.17 to 18.66μM. Xu, KangPing oth Xu, PingSheng oth Li, XiaoMin oth Cheng, Fei oth Li, Jing oth Yu, Xia oth Cao, DongSheng oth Li, Dan oth Zeng, Wei oth Zhang, GuoGang oth Tan, GuiShan oth Enthalten in Elsevier Science Coelho, Cássio Giorgio Couto ELSEVIER MASE-EGTI: An agent-based simulator for environmental land change 2021 the journal of the study of medicinal plants Amsterdam [u.a.] (DE-627)ELV007030444 volume:116 year:2017 pages:66-71 extent:6 https://doi.org/10.1016/j.fitote.2016.11.014 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-UMW SSG-OLC-ARC SSG-OLC-TEC SSG-OLC-MAT SSG-OLC-FOR 43.03 Methoden der Umweltforschung und des Umweltschutzes VZ AR 116 2017 66-71 6 045F 570 |
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Enthalten in MASE-EGTI: An agent-based simulator for environmental land change Amsterdam [u.a.] volume:116 year:2017 pages:66-71 extent:6 |
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Enthalten in MASE-EGTI: An agent-based simulator for environmental land change Amsterdam [u.a.] volume:116 year:2017 pages:66-71 extent:6 |
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Seladoeflavones A–F, six novel flavonoids from Selaginella doederleinii |
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Six new flavonoids, seladoeflavones A–F (1–6), were isolated from the whole herbs of Selaginella doederleinii, together with one known flavonoid (7). Their structures including absolute configuration were characterized on the basis of extensive spectroscopic methods including NMR, HRMS, and electronic circular dichroism (ECD). All compounds consist of an aryl substituent at the C-3′ position of naringenin or apigenin skeletons, and compounds 1 and 6 were identified as R configurations, which are uncommonly encountered in nature. A possible biosynthetic pathway was postulated. In addition, bioassay of the isolates revealed that 5–7 exhibited moderate cytotoxicity against three human cancer cell lines NCI-H460, A549, and K562 in vitro with IC50 values ranging from 8.17 to 18.66μM. |
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Six new flavonoids, seladoeflavones A–F (1–6), were isolated from the whole herbs of Selaginella doederleinii, together with one known flavonoid (7). Their structures including absolute configuration were characterized on the basis of extensive spectroscopic methods including NMR, HRMS, and electronic circular dichroism (ECD). All compounds consist of an aryl substituent at the C-3′ position of naringenin or apigenin skeletons, and compounds 1 and 6 were identified as R configurations, which are uncommonly encountered in nature. A possible biosynthetic pathway was postulated. In addition, bioassay of the isolates revealed that 5–7 exhibited moderate cytotoxicity against three human cancer cell lines NCI-H460, A549, and K562 in vitro with IC50 values ranging from 8.17 to 18.66μM. |
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Six new flavonoids, seladoeflavones A–F (1–6), were isolated from the whole herbs of Selaginella doederleinii, together with one known flavonoid (7). Their structures including absolute configuration were characterized on the basis of extensive spectroscopic methods including NMR, HRMS, and electronic circular dichroism (ECD). All compounds consist of an aryl substituent at the C-3′ position of naringenin or apigenin skeletons, and compounds 1 and 6 were identified as R configurations, which are uncommonly encountered in nature. A possible biosynthetic pathway was postulated. In addition, bioassay of the isolates revealed that 5–7 exhibited moderate cytotoxicity against three human cancer cell lines NCI-H460, A549, and K562 in vitro with IC50 values ranging from 8.17 to 18.66μM. |
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Seladoeflavones A–F, six novel flavonoids from Selaginella doederleinii |
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