Preliminary results of human PrPC protein studied by spectroscopic techniques
• First attempt of XAS study of lyophilized PrPC-Cu(II) complex was successfully made. • Complementary, AFM has shown that PrPC main domain has around 5nm in diameter. • A protocol of fixing PrPC sample on solid substrate was developed for further study. • By using ab-initio calculations, structures...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Nowakowski, Michał [verfasserIn] |
|---|
| Format: |
E-Artikel |
|---|---|
| Sprache: |
Englisch |
| Erschienen: |
2017 |
|---|
| Schlagwörter: |
|---|
| Umfang: |
8 |
|---|
| Übergeordnetes Werk: |
Enthalten in: Editorial Comment - Unwala, Darius J. ELSEVIER, 2013, a journal on accelerators, instrumentation and techniques applied to research in nuclear and atomic physics, materials science and related fields in physics, Amsterdam [u.a.] |
|---|---|
| Übergeordnetes Werk: |
volume:411 ; year:2017 ; day:15 ; month:11 ; pages:121-128 ; extent:8 |
| Links: |
|---|
| DOI / URN: |
10.1016/j.nimb.2017.06.022 |
|---|
| Katalog-ID: |
ELV040856305 |
|---|
| LEADER | 01000caa a22002652 4500 | ||
|---|---|---|---|
| 001 | ELV040856305 | ||
| 003 | DE-627 | ||
| 005 | 20230624080541.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 180725s2017 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1016/j.nimb.2017.06.022 |2 doi | |
| 028 | 5 | 2 | |a GBV00000000000021.pica |
| 035 | |a (DE-627)ELV040856305 | ||
| 035 | |a (ELSEVIER)S0168-583X(17)30696-1 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 082 | 0 | |a 530 | |
| 082 | 0 | 4 | |a 530 |q DE-600 |
| 082 | 0 | 4 | |a 610 |q VZ |
| 082 | 0 | 4 | |a 610 |q VZ |
| 084 | |a 44.85 |2 bkl | ||
| 100 | 1 | |a Nowakowski, Michał |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Preliminary results of human PrPC protein studied by spectroscopic techniques |
| 264 | 1 | |c 2017 | |
| 300 | |a 8 | ||
| 336 | |a nicht spezifiziert |b zzz |2 rdacontent | ||
| 337 | |a nicht spezifiziert |b z |2 rdamedia | ||
| 338 | |a nicht spezifiziert |b zu |2 rdacarrier | ||
| 520 | |a • First attempt of XAS study of lyophilized PrPC-Cu(II) complex was successfully made. • Complementary, AFM has shown that PrPC main domain has around 5nm in diameter. • A protocol of fixing PrPC sample on solid substrate was developed for further study. • By using ab-initio calculations, structures of PrPC-Cu(II) binding site were proposed. • The LCF has shown two coexisting Cu(II) binding modes in sample: 4N and 3N+2O. | ||
| 650 | 7 | |a Human prion protein |2 Elsevier | |
| 650 | 7 | |a AFM |2 Elsevier | |
| 650 | 7 | |a Neurodegeneration diseases |2 Elsevier | |
| 650 | 7 | |a Copper binding |2 Elsevier | |
| 650 | 7 | |a XAS |2 Elsevier | |
| 700 | 1 | |a Czapla-Masztafiak, Joanna |4 oth | |
| 700 | 1 | |a Kozak, Maciej |4 oth | |
| 700 | 1 | |a Zhukov, Igor |4 oth | |
| 700 | 1 | |a Zhukova, Lilia |4 oth | |
| 700 | 1 | |a Szlachetko, Jakub |4 oth | |
| 700 | 1 | |a Kwiatek, Wojciech M. |4 oth | |
| 773 | 0 | 8 | |i Enthalten in |n Elsevier |a Unwala, Darius J. ELSEVIER |t Editorial Comment |d 2013 |d a journal on accelerators, instrumentation and techniques applied to research in nuclear and atomic physics, materials science and related fields in physics |g Amsterdam [u.a.] |w (DE-627)ELV011304669 |
| 773 | 1 | 8 | |g volume:411 |g year:2017 |g day:15 |g month:11 |g pages:121-128 |g extent:8 |
| 856 | 4 | 0 | |u https://doi.org/10.1016/j.nimb.2017.06.022 |3 Volltext |
| 912 | |a GBV_USEFLAG_U | ||
| 912 | |a GBV_ELV | ||
| 912 | |a SYSFLAG_U | ||
| 912 | |a SSG-OLC-PHA | ||
| 912 | |a GBV_ILN_21 | ||
| 912 | |a GBV_ILN_22 | ||
| 912 | |a GBV_ILN_24 | ||
| 912 | |a GBV_ILN_40 | ||
| 912 | |a GBV_ILN_62 | ||
| 912 | |a GBV_ILN_2001 | ||
| 912 | |a GBV_ILN_2003 | ||
| 912 | |a GBV_ILN_2005 | ||
| 912 | |a GBV_ILN_2007 | ||
| 936 | b | k | |a 44.85 |j Kardiologie |j Angiologie |q VZ |
| 951 | |a AR | ||
| 952 | |d 411 |j 2017 |b 15 |c 1115 |h 121-128 |g 8 | ||
| 953 | |2 045F |a 530 | ||
| author_variant |
m n mn |
|---|---|
| matchkey_str |
nowakowskimichaczaplamasztafiakjoannakoz:2017----:rlmnrrslsfuapppoentdebset |
| hierarchy_sort_str |
2017 |
| bklnumber |
44.85 |
| publishDate |
2017 |
| allfields |
10.1016/j.nimb.2017.06.022 doi GBV00000000000021.pica (DE-627)ELV040856305 (ELSEVIER)S0168-583X(17)30696-1 DE-627 ger DE-627 rakwb eng 530 530 DE-600 610 VZ 610 VZ 44.85 bkl Nowakowski, Michał verfasserin aut Preliminary results of human PrPC protein studied by spectroscopic techniques 2017 8 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier • First attempt of XAS study of lyophilized PrPC-Cu(II) complex was successfully made. • Complementary, AFM has shown that PrPC main domain has around 5nm in diameter. • A protocol of fixing PrPC sample on solid substrate was developed for further study. • By using ab-initio calculations, structures of PrPC-Cu(II) binding site were proposed. • The LCF has shown two coexisting Cu(II) binding modes in sample: 4N and 3N+2O. Human prion protein Elsevier AFM Elsevier Neurodegeneration diseases Elsevier Copper binding Elsevier XAS Elsevier Czapla-Masztafiak, Joanna oth Kozak, Maciej oth Zhukov, Igor oth Zhukova, Lilia oth Szlachetko, Jakub oth Kwiatek, Wojciech M. oth Enthalten in Elsevier Unwala, Darius J. ELSEVIER Editorial Comment 2013 a journal on accelerators, instrumentation and techniques applied to research in nuclear and atomic physics, materials science and related fields in physics Amsterdam [u.a.] (DE-627)ELV011304669 volume:411 year:2017 day:15 month:11 pages:121-128 extent:8 https://doi.org/10.1016/j.nimb.2017.06.022 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA GBV_ILN_21 GBV_ILN_22 GBV_ILN_24 GBV_ILN_40 GBV_ILN_62 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2007 44.85 Kardiologie Angiologie VZ AR 411 2017 15 1115 121-128 8 045F 530 |
| spelling |
10.1016/j.nimb.2017.06.022 doi GBV00000000000021.pica (DE-627)ELV040856305 (ELSEVIER)S0168-583X(17)30696-1 DE-627 ger DE-627 rakwb eng 530 530 DE-600 610 VZ 610 VZ 44.85 bkl Nowakowski, Michał verfasserin aut Preliminary results of human PrPC protein studied by spectroscopic techniques 2017 8 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier • First attempt of XAS study of lyophilized PrPC-Cu(II) complex was successfully made. • Complementary, AFM has shown that PrPC main domain has around 5nm in diameter. • A protocol of fixing PrPC sample on solid substrate was developed for further study. • By using ab-initio calculations, structures of PrPC-Cu(II) binding site were proposed. • The LCF has shown two coexisting Cu(II) binding modes in sample: 4N and 3N+2O. Human prion protein Elsevier AFM Elsevier Neurodegeneration diseases Elsevier Copper binding Elsevier XAS Elsevier Czapla-Masztafiak, Joanna oth Kozak, Maciej oth Zhukov, Igor oth Zhukova, Lilia oth Szlachetko, Jakub oth Kwiatek, Wojciech M. oth Enthalten in Elsevier Unwala, Darius J. ELSEVIER Editorial Comment 2013 a journal on accelerators, instrumentation and techniques applied to research in nuclear and atomic physics, materials science and related fields in physics Amsterdam [u.a.] (DE-627)ELV011304669 volume:411 year:2017 day:15 month:11 pages:121-128 extent:8 https://doi.org/10.1016/j.nimb.2017.06.022 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA GBV_ILN_21 GBV_ILN_22 GBV_ILN_24 GBV_ILN_40 GBV_ILN_62 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2007 44.85 Kardiologie Angiologie VZ AR 411 2017 15 1115 121-128 8 045F 530 |
| allfields_unstemmed |
10.1016/j.nimb.2017.06.022 doi GBV00000000000021.pica (DE-627)ELV040856305 (ELSEVIER)S0168-583X(17)30696-1 DE-627 ger DE-627 rakwb eng 530 530 DE-600 610 VZ 610 VZ 44.85 bkl Nowakowski, Michał verfasserin aut Preliminary results of human PrPC protein studied by spectroscopic techniques 2017 8 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier • First attempt of XAS study of lyophilized PrPC-Cu(II) complex was successfully made. • Complementary, AFM has shown that PrPC main domain has around 5nm in diameter. • A protocol of fixing PrPC sample on solid substrate was developed for further study. • By using ab-initio calculations, structures of PrPC-Cu(II) binding site were proposed. • The LCF has shown two coexisting Cu(II) binding modes in sample: 4N and 3N+2O. Human prion protein Elsevier AFM Elsevier Neurodegeneration diseases Elsevier Copper binding Elsevier XAS Elsevier Czapla-Masztafiak, Joanna oth Kozak, Maciej oth Zhukov, Igor oth Zhukova, Lilia oth Szlachetko, Jakub oth Kwiatek, Wojciech M. oth Enthalten in Elsevier Unwala, Darius J. ELSEVIER Editorial Comment 2013 a journal on accelerators, instrumentation and techniques applied to research in nuclear and atomic physics, materials science and related fields in physics Amsterdam [u.a.] (DE-627)ELV011304669 volume:411 year:2017 day:15 month:11 pages:121-128 extent:8 https://doi.org/10.1016/j.nimb.2017.06.022 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA GBV_ILN_21 GBV_ILN_22 GBV_ILN_24 GBV_ILN_40 GBV_ILN_62 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2007 44.85 Kardiologie Angiologie VZ AR 411 2017 15 1115 121-128 8 045F 530 |
| allfieldsGer |
10.1016/j.nimb.2017.06.022 doi GBV00000000000021.pica (DE-627)ELV040856305 (ELSEVIER)S0168-583X(17)30696-1 DE-627 ger DE-627 rakwb eng 530 530 DE-600 610 VZ 610 VZ 44.85 bkl Nowakowski, Michał verfasserin aut Preliminary results of human PrPC protein studied by spectroscopic techniques 2017 8 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier • First attempt of XAS study of lyophilized PrPC-Cu(II) complex was successfully made. • Complementary, AFM has shown that PrPC main domain has around 5nm in diameter. • A protocol of fixing PrPC sample on solid substrate was developed for further study. • By using ab-initio calculations, structures of PrPC-Cu(II) binding site were proposed. • The LCF has shown two coexisting Cu(II) binding modes in sample: 4N and 3N+2O. Human prion protein Elsevier AFM Elsevier Neurodegeneration diseases Elsevier Copper binding Elsevier XAS Elsevier Czapla-Masztafiak, Joanna oth Kozak, Maciej oth Zhukov, Igor oth Zhukova, Lilia oth Szlachetko, Jakub oth Kwiatek, Wojciech M. oth Enthalten in Elsevier Unwala, Darius J. ELSEVIER Editorial Comment 2013 a journal on accelerators, instrumentation and techniques applied to research in nuclear and atomic physics, materials science and related fields in physics Amsterdam [u.a.] (DE-627)ELV011304669 volume:411 year:2017 day:15 month:11 pages:121-128 extent:8 https://doi.org/10.1016/j.nimb.2017.06.022 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA GBV_ILN_21 GBV_ILN_22 GBV_ILN_24 GBV_ILN_40 GBV_ILN_62 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2007 44.85 Kardiologie Angiologie VZ AR 411 2017 15 1115 121-128 8 045F 530 |
| allfieldsSound |
10.1016/j.nimb.2017.06.022 doi GBV00000000000021.pica (DE-627)ELV040856305 (ELSEVIER)S0168-583X(17)30696-1 DE-627 ger DE-627 rakwb eng 530 530 DE-600 610 VZ 610 VZ 44.85 bkl Nowakowski, Michał verfasserin aut Preliminary results of human PrPC protein studied by spectroscopic techniques 2017 8 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier • First attempt of XAS study of lyophilized PrPC-Cu(II) complex was successfully made. • Complementary, AFM has shown that PrPC main domain has around 5nm in diameter. • A protocol of fixing PrPC sample on solid substrate was developed for further study. • By using ab-initio calculations, structures of PrPC-Cu(II) binding site were proposed. • The LCF has shown two coexisting Cu(II) binding modes in sample: 4N and 3N+2O. Human prion protein Elsevier AFM Elsevier Neurodegeneration diseases Elsevier Copper binding Elsevier XAS Elsevier Czapla-Masztafiak, Joanna oth Kozak, Maciej oth Zhukov, Igor oth Zhukova, Lilia oth Szlachetko, Jakub oth Kwiatek, Wojciech M. oth Enthalten in Elsevier Unwala, Darius J. ELSEVIER Editorial Comment 2013 a journal on accelerators, instrumentation and techniques applied to research in nuclear and atomic physics, materials science and related fields in physics Amsterdam [u.a.] (DE-627)ELV011304669 volume:411 year:2017 day:15 month:11 pages:121-128 extent:8 https://doi.org/10.1016/j.nimb.2017.06.022 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA GBV_ILN_21 GBV_ILN_22 GBV_ILN_24 GBV_ILN_40 GBV_ILN_62 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2007 44.85 Kardiologie Angiologie VZ AR 411 2017 15 1115 121-128 8 045F 530 |
| language |
English |
| source |
Enthalten in Editorial Comment Amsterdam [u.a.] volume:411 year:2017 day:15 month:11 pages:121-128 extent:8 |
| sourceStr |
Enthalten in Editorial Comment Amsterdam [u.a.] volume:411 year:2017 day:15 month:11 pages:121-128 extent:8 |
| format_phy_str_mv |
Article |
| bklname |
Kardiologie Angiologie |
| institution |
findex.gbv.de |
| topic_facet |
Human prion protein AFM Neurodegeneration diseases Copper binding XAS |
| dewey-raw |
530 |
| isfreeaccess_bool |
false |
| container_title |
Editorial Comment |
| authorswithroles_txt_mv |
Nowakowski, Michał @@aut@@ Czapla-Masztafiak, Joanna @@oth@@ Kozak, Maciej @@oth@@ Zhukov, Igor @@oth@@ Zhukova, Lilia @@oth@@ Szlachetko, Jakub @@oth@@ Kwiatek, Wojciech M. @@oth@@ |
| publishDateDaySort_date |
2017-01-15T00:00:00Z |
| hierarchy_top_id |
ELV011304669 |
| dewey-sort |
3530 |
| id |
ELV040856305 |
| language_de |
englisch |
| fullrecord |
<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">ELV040856305</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230624080541.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">180725s2017 xx |||||o 00| ||eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1016/j.nimb.2017.06.022</subfield><subfield code="2">doi</subfield></datafield><datafield tag="028" ind1="5" ind2="2"><subfield code="a">GBV00000000000021.pica</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)ELV040856305</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(ELSEVIER)S0168-583X(17)30696-1</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="082" ind1="0" ind2=" "><subfield code="a">530</subfield></datafield><datafield tag="082" ind1="0" ind2="4"><subfield code="a">530</subfield><subfield code="q">DE-600</subfield></datafield><datafield tag="082" ind1="0" ind2="4"><subfield code="a">610</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="082" ind1="0" ind2="4"><subfield code="a">610</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">44.85</subfield><subfield code="2">bkl</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Nowakowski, Michał</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Preliminary results of human PrPC protein studied by spectroscopic techniques</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2017</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">8</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zzz</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">z</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zu</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">• First attempt of XAS study of lyophilized PrPC-Cu(II) complex was successfully made. • Complementary, AFM has shown that PrPC main domain has around 5nm in diameter. • A protocol of fixing PrPC sample on solid substrate was developed for further study. • By using ab-initio calculations, structures of PrPC-Cu(II) binding site were proposed. • The LCF has shown two coexisting Cu(II) binding modes in sample: 4N and 3N+2O.</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Human prion protein</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">AFM</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Neurodegeneration diseases</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Copper binding</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">XAS</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Czapla-Masztafiak, Joanna</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Kozak, Maciej</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Zhukov, Igor</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Zhukova, Lilia</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Szlachetko, Jakub</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Kwiatek, Wojciech M.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">Enthalten in</subfield><subfield code="n">Elsevier</subfield><subfield code="a">Unwala, Darius J. ELSEVIER</subfield><subfield code="t">Editorial Comment</subfield><subfield code="d">2013</subfield><subfield code="d">a journal on accelerators, instrumentation and techniques applied to research in nuclear and atomic physics, materials science and related fields in physics</subfield><subfield code="g">Amsterdam [u.a.]</subfield><subfield code="w">(DE-627)ELV011304669</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:411</subfield><subfield code="g">year:2017</subfield><subfield code="g">day:15</subfield><subfield code="g">month:11</subfield><subfield code="g">pages:121-128</subfield><subfield code="g">extent:8</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://doi.org/10.1016/j.nimb.2017.06.022</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_U</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ELV</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SYSFLAG_U</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SSG-OLC-PHA</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_21</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_22</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_24</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_40</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_62</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2001</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2003</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2005</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2007</subfield></datafield><datafield tag="936" ind1="b" ind2="k"><subfield code="a">44.85</subfield><subfield code="j">Kardiologie</subfield><subfield code="j">Angiologie</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">411</subfield><subfield code="j">2017</subfield><subfield code="b">15</subfield><subfield code="c">1115</subfield><subfield code="h">121-128</subfield><subfield code="g">8</subfield></datafield><datafield tag="953" ind1=" " ind2=" "><subfield code="2">045F</subfield><subfield code="a">530</subfield></datafield></record></collection>
|
| author |
Nowakowski, Michał |
| spellingShingle |
Nowakowski, Michał ddc 530 ddc 610 bkl 44.85 Elsevier Human prion protein Elsevier AFM Elsevier Neurodegeneration diseases Elsevier Copper binding Elsevier XAS Preliminary results of human PrPC protein studied by spectroscopic techniques |
| authorStr |
Nowakowski, Michał |
| ppnlink_with_tag_str_mv |
@@773@@(DE-627)ELV011304669 |
| format |
electronic Article |
| dewey-ones |
530 - Physics 610 - Medicine & health |
| delete_txt_mv |
keep |
| author_role |
aut |
| collection |
elsevier |
| remote_str |
true |
| illustrated |
Not Illustrated |
| topic_title |
530 530 DE-600 610 VZ 44.85 bkl Preliminary results of human PrPC protein studied by spectroscopic techniques Human prion protein Elsevier AFM Elsevier Neurodegeneration diseases Elsevier Copper binding Elsevier XAS Elsevier |
| topic |
ddc 530 ddc 610 bkl 44.85 Elsevier Human prion protein Elsevier AFM Elsevier Neurodegeneration diseases Elsevier Copper binding Elsevier XAS |
| topic_unstemmed |
ddc 530 ddc 610 bkl 44.85 Elsevier Human prion protein Elsevier AFM Elsevier Neurodegeneration diseases Elsevier Copper binding Elsevier XAS |
| topic_browse |
ddc 530 ddc 610 bkl 44.85 Elsevier Human prion protein Elsevier AFM Elsevier Neurodegeneration diseases Elsevier Copper binding Elsevier XAS |
| format_facet |
Elektronische Aufsätze Aufsätze Elektronische Ressource |
| format_main_str_mv |
Text Zeitschrift/Artikel |
| carriertype_str_mv |
zu |
| author2_variant |
j c m jcm m k mk i z iz l z lz j s js w m k wm wmk |
| hierarchy_parent_title |
Editorial Comment |
| hierarchy_parent_id |
ELV011304669 |
| dewey-tens |
530 - Physics 610 - Medicine & health |
| hierarchy_top_title |
Editorial Comment |
| isfreeaccess_txt |
false |
| familylinks_str_mv |
(DE-627)ELV011304669 |
| title |
Preliminary results of human PrPC protein studied by spectroscopic techniques |
| ctrlnum |
(DE-627)ELV040856305 (ELSEVIER)S0168-583X(17)30696-1 |
| title_full |
Preliminary results of human PrPC protein studied by spectroscopic techniques |
| author_sort |
Nowakowski, Michał |
| journal |
Editorial Comment |
| journalStr |
Editorial Comment |
| lang_code |
eng |
| isOA_bool |
false |
| dewey-hundreds |
500 - Science 600 - Technology |
| recordtype |
marc |
| publishDateSort |
2017 |
| contenttype_str_mv |
zzz |
| container_start_page |
121 |
| author_browse |
Nowakowski, Michał |
| container_volume |
411 |
| physical |
8 |
| class |
530 530 DE-600 610 VZ 44.85 bkl |
| format_se |
Elektronische Aufsätze |
| author-letter |
Nowakowski, Michał |
| doi_str_mv |
10.1016/j.nimb.2017.06.022 |
| dewey-full |
530 610 |
| title_sort |
preliminary results of human prpc protein studied by spectroscopic techniques |
| title_auth |
Preliminary results of human PrPC protein studied by spectroscopic techniques |
| abstract |
• First attempt of XAS study of lyophilized PrPC-Cu(II) complex was successfully made. • Complementary, AFM has shown that PrPC main domain has around 5nm in diameter. • A protocol of fixing PrPC sample on solid substrate was developed for further study. • By using ab-initio calculations, structures of PrPC-Cu(II) binding site were proposed. • The LCF has shown two coexisting Cu(II) binding modes in sample: 4N and 3N+2O. |
| abstractGer |
• First attempt of XAS study of lyophilized PrPC-Cu(II) complex was successfully made. • Complementary, AFM has shown that PrPC main domain has around 5nm in diameter. • A protocol of fixing PrPC sample on solid substrate was developed for further study. • By using ab-initio calculations, structures of PrPC-Cu(II) binding site were proposed. • The LCF has shown two coexisting Cu(II) binding modes in sample: 4N and 3N+2O. |
| abstract_unstemmed |
• First attempt of XAS study of lyophilized PrPC-Cu(II) complex was successfully made. • Complementary, AFM has shown that PrPC main domain has around 5nm in diameter. • A protocol of fixing PrPC sample on solid substrate was developed for further study. • By using ab-initio calculations, structures of PrPC-Cu(II) binding site were proposed. • The LCF has shown two coexisting Cu(II) binding modes in sample: 4N and 3N+2O. |
| collection_details |
GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA GBV_ILN_21 GBV_ILN_22 GBV_ILN_24 GBV_ILN_40 GBV_ILN_62 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2007 |
| title_short |
Preliminary results of human PrPC protein studied by spectroscopic techniques |
| url |
https://doi.org/10.1016/j.nimb.2017.06.022 |
| remote_bool |
true |
| author2 |
Czapla-Masztafiak, Joanna Kozak, Maciej Zhukov, Igor Zhukova, Lilia Szlachetko, Jakub Kwiatek, Wojciech M. |
| author2Str |
Czapla-Masztafiak, Joanna Kozak, Maciej Zhukov, Igor Zhukova, Lilia Szlachetko, Jakub Kwiatek, Wojciech M. |
| ppnlink |
ELV011304669 |
| mediatype_str_mv |
z |
| isOA_txt |
false |
| hochschulschrift_bool |
false |
| author2_role |
oth oth oth oth oth oth |
| doi_str |
10.1016/j.nimb.2017.06.022 |
| up_date |
2024-07-06T18:34:50.205Z |
| _version_ |
1803855740488646656 |
| fullrecord_marcxml |
<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">ELV040856305</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230624080541.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">180725s2017 xx |||||o 00| ||eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1016/j.nimb.2017.06.022</subfield><subfield code="2">doi</subfield></datafield><datafield tag="028" ind1="5" ind2="2"><subfield code="a">GBV00000000000021.pica</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)ELV040856305</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(ELSEVIER)S0168-583X(17)30696-1</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="082" ind1="0" ind2=" "><subfield code="a">530</subfield></datafield><datafield tag="082" ind1="0" ind2="4"><subfield code="a">530</subfield><subfield code="q">DE-600</subfield></datafield><datafield tag="082" ind1="0" ind2="4"><subfield code="a">610</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="082" ind1="0" ind2="4"><subfield code="a">610</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">44.85</subfield><subfield code="2">bkl</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Nowakowski, Michał</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Preliminary results of human PrPC protein studied by spectroscopic techniques</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2017</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">8</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zzz</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">z</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zu</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">• First attempt of XAS study of lyophilized PrPC-Cu(II) complex was successfully made. • Complementary, AFM has shown that PrPC main domain has around 5nm in diameter. • A protocol of fixing PrPC sample on solid substrate was developed for further study. • By using ab-initio calculations, structures of PrPC-Cu(II) binding site were proposed. • The LCF has shown two coexisting Cu(II) binding modes in sample: 4N and 3N+2O.</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Human prion protein</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">AFM</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Neurodegeneration diseases</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Copper binding</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">XAS</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Czapla-Masztafiak, Joanna</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Kozak, Maciej</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Zhukov, Igor</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Zhukova, Lilia</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Szlachetko, Jakub</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Kwiatek, Wojciech M.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">Enthalten in</subfield><subfield code="n">Elsevier</subfield><subfield code="a">Unwala, Darius J. ELSEVIER</subfield><subfield code="t">Editorial Comment</subfield><subfield code="d">2013</subfield><subfield code="d">a journal on accelerators, instrumentation and techniques applied to research in nuclear and atomic physics, materials science and related fields in physics</subfield><subfield code="g">Amsterdam [u.a.]</subfield><subfield code="w">(DE-627)ELV011304669</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:411</subfield><subfield code="g">year:2017</subfield><subfield code="g">day:15</subfield><subfield code="g">month:11</subfield><subfield code="g">pages:121-128</subfield><subfield code="g">extent:8</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://doi.org/10.1016/j.nimb.2017.06.022</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_U</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ELV</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SYSFLAG_U</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SSG-OLC-PHA</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_21</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_22</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_24</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_40</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_62</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2001</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2003</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2005</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2007</subfield></datafield><datafield tag="936" ind1="b" ind2="k"><subfield code="a">44.85</subfield><subfield code="j">Kardiologie</subfield><subfield code="j">Angiologie</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">411</subfield><subfield code="j">2017</subfield><subfield code="b">15</subfield><subfield code="c">1115</subfield><subfield code="h">121-128</subfield><subfield code="g">8</subfield></datafield><datafield tag="953" ind1=" " ind2=" "><subfield code="2">045F</subfield><subfield code="a">530</subfield></datafield></record></collection>
|
| score |
7.4023 |