Molecular characterization and expression analyses of the Viperin gene in Larimichthys crocea (Family: Sciaenidae)
In this study, we sequenced and characterized an interferon-stimulated gene Viperin homologue, LcViperin, from large yellow croaker (Larimichthys crocea). The LcViperin encodes 354 amino acids and contains an N-terminal amphipathic α-helix domain, a radical S-adenosyl-l-methionine (SAM) domain and a...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Zhang, Jianshe [verfasserIn] |
|---|
| Format: |
E-Artikel |
|---|---|
| Sprache: |
Englisch |
| Erschienen: |
2018transfer abstract |
|---|
| Schlagwörter: |
|---|
| Umfang: |
8 |
|---|
| Übergeordnetes Werk: |
Enthalten in: GABAergic mRNA expression is differentially expressed across the prelimbic and orbitofrontal cortices of rats sensitized to methamphetamine: Relevance to psychosis - Wearne, Travis A. ELSEVIER, 2016transfer abstract, ontogeny, phylogeny, aging : the official journal of the International Society of Developmental and Comparative Immunology, Amsterdam [u.a.] |
|---|---|
| Übergeordnetes Werk: |
volume:79 ; year:2018 ; pages:59-66 ; extent:8 |
| Links: |
|---|
| DOI / URN: |
10.1016/j.dci.2017.10.013 |
|---|
| Katalog-ID: |
ELV04104424X |
|---|
| LEADER | 01000caa a22002652 4500 | ||
|---|---|---|---|
| 001 | ELV04104424X | ||
| 003 | DE-627 | ||
| 005 | 20230625233543.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 180725s2018 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1016/j.dci.2017.10.013 |2 doi | |
| 028 | 5 | 2 | |a GBV00000000000273A.pica |
| 035 | |a (DE-627)ELV04104424X | ||
| 035 | |a (ELSEVIER)S0145-305X(17)30378-6 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 082 | 0 | |a 610 | |
| 082 | 0 | 4 | |a 610 |q DE-600 |
| 082 | 0 | 4 | |a 610 |q VZ |
| 082 | 0 | 4 | |a 610 |q VZ |
| 084 | |a 44.88 |2 bkl | ||
| 100 | 1 | |a Zhang, Jianshe |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Molecular characterization and expression analyses of the Viperin gene in Larimichthys crocea (Family: Sciaenidae) |
| 264 | 1 | |c 2018transfer abstract | |
| 300 | |a 8 | ||
| 336 | |a nicht spezifiziert |b zzz |2 rdacontent | ||
| 337 | |a nicht spezifiziert |b z |2 rdamedia | ||
| 338 | |a nicht spezifiziert |b zu |2 rdacarrier | ||
| 520 | |a In this study, we sequenced and characterized an interferon-stimulated gene Viperin homologue, LcViperin, from large yellow croaker (Larimichthys crocea). The LcViperin encodes 354 amino acids and contains an N-terminal amphipathic α-helix domain, a radical S-adenosyl-l-methionine (SAM) domain and a highly conserved C-terminal domain. The analyses of LcViperin promoter region revealed nine kinds of putative transcriptional factor binding sites, including five putative ICSBP (IRF-8) binding sites and one putative IRF-1 binding site, indicating that the expression of LcViperin might be induced by the type I IFN response. Phylogenetic analyses based on amino acid sequences showed that the Viperin of large yellow croaker is clustered together with its counterparts from other teleost fishes. The Real-time PCR analyses showed that the LcViperin was found to be ubiquitously expressed in ten examined tissues in large yellow croaker, with predominant expression in peripheral blood, followed by heart and gill. Expression analyses showed that the LcViperin was rapidly and significantly upregulated in vivo after poly (I:C) challenge in peripheral blood, head kidney, spleen and liver tissues. The results indicate that the LcViperin might play a pivotal role in antiviral immune responses. | ||
| 520 | |a In this study, we sequenced and characterized an interferon-stimulated gene Viperin homologue, LcViperin, from large yellow croaker (Larimichthys crocea). The LcViperin encodes 354 amino acids and contains an N-terminal amphipathic α-helix domain, a radical S-adenosyl-l-methionine (SAM) domain and a highly conserved C-terminal domain. The analyses of LcViperin promoter region revealed nine kinds of putative transcriptional factor binding sites, including five putative ICSBP (IRF-8) binding sites and one putative IRF-1 binding site, indicating that the expression of LcViperin might be induced by the type I IFN response. Phylogenetic analyses based on amino acid sequences showed that the Viperin of large yellow croaker is clustered together with its counterparts from other teleost fishes. The Real-time PCR analyses showed that the LcViperin was found to be ubiquitously expressed in ten examined tissues in large yellow croaker, with predominant expression in peripheral blood, followed by heart and gill. Expression analyses showed that the LcViperin was rapidly and significantly upregulated in vivo after poly (I:C) challenge in peripheral blood, head kidney, spleen and liver tissues. The results indicate that the LcViperin might play a pivotal role in antiviral immune responses. | ||
| 650 | 7 | |a Interferon-stimulated gene |2 Elsevier | |
| 650 | 7 | |a Innate antiviral immunity |2 Elsevier | |
| 650 | 7 | |a poly (I:C) |2 Elsevier | |
| 650 | 7 | |a RT-qPCR |2 Elsevier | |
| 650 | 7 | |a Large yellow croaker |2 Elsevier | |
| 700 | 1 | |a Liu, Cheng |4 oth | |
| 700 | 1 | |a Zhao, Shujiang |4 oth | |
| 700 | 1 | |a Guo, Shaoyu |4 oth | |
| 700 | 1 | |a Shen, Bin |4 oth | |
| 773 | 0 | 8 | |i Enthalten in |n Elsevier Science |a Wearne, Travis A. ELSEVIER |t GABAergic mRNA expression is differentially expressed across the prelimbic and orbitofrontal cortices of rats sensitized to methamphetamine: Relevance to psychosis |d 2016transfer abstract |d ontogeny, phylogeny, aging : the official journal of the International Society of Developmental and Comparative Immunology |g Amsterdam [u.a.] |w (DE-627)ELV019920881 |
| 773 | 1 | 8 | |g volume:79 |g year:2018 |g pages:59-66 |g extent:8 |
| 856 | 4 | 0 | |u https://doi.org/10.1016/j.dci.2017.10.013 |3 Volltext |
| 912 | |a GBV_USEFLAG_U | ||
| 912 | |a GBV_ELV | ||
| 912 | |a SYSFLAG_U | ||
| 912 | |a SSG-OLC-PHA | ||
| 912 | |a GBV_ILN_60 | ||
| 936 | b | k | |a 44.88 |j Urologie |j Nephrologie |q VZ |
| 951 | |a AR | ||
| 952 | |d 79 |j 2018 |h 59-66 |g 8 | ||
| 953 | |2 045F |a 610 | ||
| author_variant |
j z jz |
|---|---|
| matchkey_str |
zhangjiansheliuchengzhaoshujiangguoshaoy:2018----:oeuacaatrztoadxrsinnlssfhvprneenaiih |
| hierarchy_sort_str |
2018transfer abstract |
| bklnumber |
44.88 |
| publishDate |
2018 |
| allfields |
10.1016/j.dci.2017.10.013 doi GBV00000000000273A.pica (DE-627)ELV04104424X (ELSEVIER)S0145-305X(17)30378-6 DE-627 ger DE-627 rakwb eng 610 610 DE-600 610 VZ 610 VZ 44.88 bkl Zhang, Jianshe verfasserin aut Molecular characterization and expression analyses of the Viperin gene in Larimichthys crocea (Family: Sciaenidae) 2018transfer abstract 8 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier In this study, we sequenced and characterized an interferon-stimulated gene Viperin homologue, LcViperin, from large yellow croaker (Larimichthys crocea). The LcViperin encodes 354 amino acids and contains an N-terminal amphipathic α-helix domain, a radical S-adenosyl-l-methionine (SAM) domain and a highly conserved C-terminal domain. The analyses of LcViperin promoter region revealed nine kinds of putative transcriptional factor binding sites, including five putative ICSBP (IRF-8) binding sites and one putative IRF-1 binding site, indicating that the expression of LcViperin might be induced by the type I IFN response. Phylogenetic analyses based on amino acid sequences showed that the Viperin of large yellow croaker is clustered together with its counterparts from other teleost fishes. The Real-time PCR analyses showed that the LcViperin was found to be ubiquitously expressed in ten examined tissues in large yellow croaker, with predominant expression in peripheral blood, followed by heart and gill. Expression analyses showed that the LcViperin was rapidly and significantly upregulated in vivo after poly (I:C) challenge in peripheral blood, head kidney, spleen and liver tissues. The results indicate that the LcViperin might play a pivotal role in antiviral immune responses. In this study, we sequenced and characterized an interferon-stimulated gene Viperin homologue, LcViperin, from large yellow croaker (Larimichthys crocea). The LcViperin encodes 354 amino acids and contains an N-terminal amphipathic α-helix domain, a radical S-adenosyl-l-methionine (SAM) domain and a highly conserved C-terminal domain. The analyses of LcViperin promoter region revealed nine kinds of putative transcriptional factor binding sites, including five putative ICSBP (IRF-8) binding sites and one putative IRF-1 binding site, indicating that the expression of LcViperin might be induced by the type I IFN response. Phylogenetic analyses based on amino acid sequences showed that the Viperin of large yellow croaker is clustered together with its counterparts from other teleost fishes. The Real-time PCR analyses showed that the LcViperin was found to be ubiquitously expressed in ten examined tissues in large yellow croaker, with predominant expression in peripheral blood, followed by heart and gill. Expression analyses showed that the LcViperin was rapidly and significantly upregulated in vivo after poly (I:C) challenge in peripheral blood, head kidney, spleen and liver tissues. The results indicate that the LcViperin might play a pivotal role in antiviral immune responses. Interferon-stimulated gene Elsevier Innate antiviral immunity Elsevier poly (I:C) Elsevier RT-qPCR Elsevier Large yellow croaker Elsevier Liu, Cheng oth Zhao, Shujiang oth Guo, Shaoyu oth Shen, Bin oth Enthalten in Elsevier Science Wearne, Travis A. ELSEVIER GABAergic mRNA expression is differentially expressed across the prelimbic and orbitofrontal cortices of rats sensitized to methamphetamine: Relevance to psychosis 2016transfer abstract ontogeny, phylogeny, aging : the official journal of the International Society of Developmental and Comparative Immunology Amsterdam [u.a.] (DE-627)ELV019920881 volume:79 year:2018 pages:59-66 extent:8 https://doi.org/10.1016/j.dci.2017.10.013 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA GBV_ILN_60 44.88 Urologie Nephrologie VZ AR 79 2018 59-66 8 045F 610 |
| spelling |
10.1016/j.dci.2017.10.013 doi GBV00000000000273A.pica (DE-627)ELV04104424X (ELSEVIER)S0145-305X(17)30378-6 DE-627 ger DE-627 rakwb eng 610 610 DE-600 610 VZ 610 VZ 44.88 bkl Zhang, Jianshe verfasserin aut Molecular characterization and expression analyses of the Viperin gene in Larimichthys crocea (Family: Sciaenidae) 2018transfer abstract 8 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier In this study, we sequenced and characterized an interferon-stimulated gene Viperin homologue, LcViperin, from large yellow croaker (Larimichthys crocea). The LcViperin encodes 354 amino acids and contains an N-terminal amphipathic α-helix domain, a radical S-adenosyl-l-methionine (SAM) domain and a highly conserved C-terminal domain. The analyses of LcViperin promoter region revealed nine kinds of putative transcriptional factor binding sites, including five putative ICSBP (IRF-8) binding sites and one putative IRF-1 binding site, indicating that the expression of LcViperin might be induced by the type I IFN response. Phylogenetic analyses based on amino acid sequences showed that the Viperin of large yellow croaker is clustered together with its counterparts from other teleost fishes. The Real-time PCR analyses showed that the LcViperin was found to be ubiquitously expressed in ten examined tissues in large yellow croaker, with predominant expression in peripheral blood, followed by heart and gill. Expression analyses showed that the LcViperin was rapidly and significantly upregulated in vivo after poly (I:C) challenge in peripheral blood, head kidney, spleen and liver tissues. The results indicate that the LcViperin might play a pivotal role in antiviral immune responses. In this study, we sequenced and characterized an interferon-stimulated gene Viperin homologue, LcViperin, from large yellow croaker (Larimichthys crocea). The LcViperin encodes 354 amino acids and contains an N-terminal amphipathic α-helix domain, a radical S-adenosyl-l-methionine (SAM) domain and a highly conserved C-terminal domain. The analyses of LcViperin promoter region revealed nine kinds of putative transcriptional factor binding sites, including five putative ICSBP (IRF-8) binding sites and one putative IRF-1 binding site, indicating that the expression of LcViperin might be induced by the type I IFN response. Phylogenetic analyses based on amino acid sequences showed that the Viperin of large yellow croaker is clustered together with its counterparts from other teleost fishes. The Real-time PCR analyses showed that the LcViperin was found to be ubiquitously expressed in ten examined tissues in large yellow croaker, with predominant expression in peripheral blood, followed by heart and gill. Expression analyses showed that the LcViperin was rapidly and significantly upregulated in vivo after poly (I:C) challenge in peripheral blood, head kidney, spleen and liver tissues. The results indicate that the LcViperin might play a pivotal role in antiviral immune responses. Interferon-stimulated gene Elsevier Innate antiviral immunity Elsevier poly (I:C) Elsevier RT-qPCR Elsevier Large yellow croaker Elsevier Liu, Cheng oth Zhao, Shujiang oth Guo, Shaoyu oth Shen, Bin oth Enthalten in Elsevier Science Wearne, Travis A. ELSEVIER GABAergic mRNA expression is differentially expressed across the prelimbic and orbitofrontal cortices of rats sensitized to methamphetamine: Relevance to psychosis 2016transfer abstract ontogeny, phylogeny, aging : the official journal of the International Society of Developmental and Comparative Immunology Amsterdam [u.a.] (DE-627)ELV019920881 volume:79 year:2018 pages:59-66 extent:8 https://doi.org/10.1016/j.dci.2017.10.013 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA GBV_ILN_60 44.88 Urologie Nephrologie VZ AR 79 2018 59-66 8 045F 610 |
| allfields_unstemmed |
10.1016/j.dci.2017.10.013 doi GBV00000000000273A.pica (DE-627)ELV04104424X (ELSEVIER)S0145-305X(17)30378-6 DE-627 ger DE-627 rakwb eng 610 610 DE-600 610 VZ 610 VZ 44.88 bkl Zhang, Jianshe verfasserin aut Molecular characterization and expression analyses of the Viperin gene in Larimichthys crocea (Family: Sciaenidae) 2018transfer abstract 8 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier In this study, we sequenced and characterized an interferon-stimulated gene Viperin homologue, LcViperin, from large yellow croaker (Larimichthys crocea). The LcViperin encodes 354 amino acids and contains an N-terminal amphipathic α-helix domain, a radical S-adenosyl-l-methionine (SAM) domain and a highly conserved C-terminal domain. The analyses of LcViperin promoter region revealed nine kinds of putative transcriptional factor binding sites, including five putative ICSBP (IRF-8) binding sites and one putative IRF-1 binding site, indicating that the expression of LcViperin might be induced by the type I IFN response. Phylogenetic analyses based on amino acid sequences showed that the Viperin of large yellow croaker is clustered together with its counterparts from other teleost fishes. The Real-time PCR analyses showed that the LcViperin was found to be ubiquitously expressed in ten examined tissues in large yellow croaker, with predominant expression in peripheral blood, followed by heart and gill. Expression analyses showed that the LcViperin was rapidly and significantly upregulated in vivo after poly (I:C) challenge in peripheral blood, head kidney, spleen and liver tissues. The results indicate that the LcViperin might play a pivotal role in antiviral immune responses. In this study, we sequenced and characterized an interferon-stimulated gene Viperin homologue, LcViperin, from large yellow croaker (Larimichthys crocea). The LcViperin encodes 354 amino acids and contains an N-terminal amphipathic α-helix domain, a radical S-adenosyl-l-methionine (SAM) domain and a highly conserved C-terminal domain. The analyses of LcViperin promoter region revealed nine kinds of putative transcriptional factor binding sites, including five putative ICSBP (IRF-8) binding sites and one putative IRF-1 binding site, indicating that the expression of LcViperin might be induced by the type I IFN response. Phylogenetic analyses based on amino acid sequences showed that the Viperin of large yellow croaker is clustered together with its counterparts from other teleost fishes. The Real-time PCR analyses showed that the LcViperin was found to be ubiquitously expressed in ten examined tissues in large yellow croaker, with predominant expression in peripheral blood, followed by heart and gill. Expression analyses showed that the LcViperin was rapidly and significantly upregulated in vivo after poly (I:C) challenge in peripheral blood, head kidney, spleen and liver tissues. The results indicate that the LcViperin might play a pivotal role in antiviral immune responses. Interferon-stimulated gene Elsevier Innate antiviral immunity Elsevier poly (I:C) Elsevier RT-qPCR Elsevier Large yellow croaker Elsevier Liu, Cheng oth Zhao, Shujiang oth Guo, Shaoyu oth Shen, Bin oth Enthalten in Elsevier Science Wearne, Travis A. ELSEVIER GABAergic mRNA expression is differentially expressed across the prelimbic and orbitofrontal cortices of rats sensitized to methamphetamine: Relevance to psychosis 2016transfer abstract ontogeny, phylogeny, aging : the official journal of the International Society of Developmental and Comparative Immunology Amsterdam [u.a.] (DE-627)ELV019920881 volume:79 year:2018 pages:59-66 extent:8 https://doi.org/10.1016/j.dci.2017.10.013 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA GBV_ILN_60 44.88 Urologie Nephrologie VZ AR 79 2018 59-66 8 045F 610 |
| allfieldsGer |
10.1016/j.dci.2017.10.013 doi GBV00000000000273A.pica (DE-627)ELV04104424X (ELSEVIER)S0145-305X(17)30378-6 DE-627 ger DE-627 rakwb eng 610 610 DE-600 610 VZ 610 VZ 44.88 bkl Zhang, Jianshe verfasserin aut Molecular characterization and expression analyses of the Viperin gene in Larimichthys crocea (Family: Sciaenidae) 2018transfer abstract 8 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier In this study, we sequenced and characterized an interferon-stimulated gene Viperin homologue, LcViperin, from large yellow croaker (Larimichthys crocea). The LcViperin encodes 354 amino acids and contains an N-terminal amphipathic α-helix domain, a radical S-adenosyl-l-methionine (SAM) domain and a highly conserved C-terminal domain. The analyses of LcViperin promoter region revealed nine kinds of putative transcriptional factor binding sites, including five putative ICSBP (IRF-8) binding sites and one putative IRF-1 binding site, indicating that the expression of LcViperin might be induced by the type I IFN response. Phylogenetic analyses based on amino acid sequences showed that the Viperin of large yellow croaker is clustered together with its counterparts from other teleost fishes. The Real-time PCR analyses showed that the LcViperin was found to be ubiquitously expressed in ten examined tissues in large yellow croaker, with predominant expression in peripheral blood, followed by heart and gill. Expression analyses showed that the LcViperin was rapidly and significantly upregulated in vivo after poly (I:C) challenge in peripheral blood, head kidney, spleen and liver tissues. The results indicate that the LcViperin might play a pivotal role in antiviral immune responses. In this study, we sequenced and characterized an interferon-stimulated gene Viperin homologue, LcViperin, from large yellow croaker (Larimichthys crocea). The LcViperin encodes 354 amino acids and contains an N-terminal amphipathic α-helix domain, a radical S-adenosyl-l-methionine (SAM) domain and a highly conserved C-terminal domain. The analyses of LcViperin promoter region revealed nine kinds of putative transcriptional factor binding sites, including five putative ICSBP (IRF-8) binding sites and one putative IRF-1 binding site, indicating that the expression of LcViperin might be induced by the type I IFN response. Phylogenetic analyses based on amino acid sequences showed that the Viperin of large yellow croaker is clustered together with its counterparts from other teleost fishes. The Real-time PCR analyses showed that the LcViperin was found to be ubiquitously expressed in ten examined tissues in large yellow croaker, with predominant expression in peripheral blood, followed by heart and gill. Expression analyses showed that the LcViperin was rapidly and significantly upregulated in vivo after poly (I:C) challenge in peripheral blood, head kidney, spleen and liver tissues. The results indicate that the LcViperin might play a pivotal role in antiviral immune responses. Interferon-stimulated gene Elsevier Innate antiviral immunity Elsevier poly (I:C) Elsevier RT-qPCR Elsevier Large yellow croaker Elsevier Liu, Cheng oth Zhao, Shujiang oth Guo, Shaoyu oth Shen, Bin oth Enthalten in Elsevier Science Wearne, Travis A. ELSEVIER GABAergic mRNA expression is differentially expressed across the prelimbic and orbitofrontal cortices of rats sensitized to methamphetamine: Relevance to psychosis 2016transfer abstract ontogeny, phylogeny, aging : the official journal of the International Society of Developmental and Comparative Immunology Amsterdam [u.a.] (DE-627)ELV019920881 volume:79 year:2018 pages:59-66 extent:8 https://doi.org/10.1016/j.dci.2017.10.013 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA GBV_ILN_60 44.88 Urologie Nephrologie VZ AR 79 2018 59-66 8 045F 610 |
| allfieldsSound |
10.1016/j.dci.2017.10.013 doi GBV00000000000273A.pica (DE-627)ELV04104424X (ELSEVIER)S0145-305X(17)30378-6 DE-627 ger DE-627 rakwb eng 610 610 DE-600 610 VZ 610 VZ 44.88 bkl Zhang, Jianshe verfasserin aut Molecular characterization and expression analyses of the Viperin gene in Larimichthys crocea (Family: Sciaenidae) 2018transfer abstract 8 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier In this study, we sequenced and characterized an interferon-stimulated gene Viperin homologue, LcViperin, from large yellow croaker (Larimichthys crocea). The LcViperin encodes 354 amino acids and contains an N-terminal amphipathic α-helix domain, a radical S-adenosyl-l-methionine (SAM) domain and a highly conserved C-terminal domain. The analyses of LcViperin promoter region revealed nine kinds of putative transcriptional factor binding sites, including five putative ICSBP (IRF-8) binding sites and one putative IRF-1 binding site, indicating that the expression of LcViperin might be induced by the type I IFN response. Phylogenetic analyses based on amino acid sequences showed that the Viperin of large yellow croaker is clustered together with its counterparts from other teleost fishes. The Real-time PCR analyses showed that the LcViperin was found to be ubiquitously expressed in ten examined tissues in large yellow croaker, with predominant expression in peripheral blood, followed by heart and gill. Expression analyses showed that the LcViperin was rapidly and significantly upregulated in vivo after poly (I:C) challenge in peripheral blood, head kidney, spleen and liver tissues. The results indicate that the LcViperin might play a pivotal role in antiviral immune responses. In this study, we sequenced and characterized an interferon-stimulated gene Viperin homologue, LcViperin, from large yellow croaker (Larimichthys crocea). The LcViperin encodes 354 amino acids and contains an N-terminal amphipathic α-helix domain, a radical S-adenosyl-l-methionine (SAM) domain and a highly conserved C-terminal domain. The analyses of LcViperin promoter region revealed nine kinds of putative transcriptional factor binding sites, including five putative ICSBP (IRF-8) binding sites and one putative IRF-1 binding site, indicating that the expression of LcViperin might be induced by the type I IFN response. Phylogenetic analyses based on amino acid sequences showed that the Viperin of large yellow croaker is clustered together with its counterparts from other teleost fishes. The Real-time PCR analyses showed that the LcViperin was found to be ubiquitously expressed in ten examined tissues in large yellow croaker, with predominant expression in peripheral blood, followed by heart and gill. Expression analyses showed that the LcViperin was rapidly and significantly upregulated in vivo after poly (I:C) challenge in peripheral blood, head kidney, spleen and liver tissues. The results indicate that the LcViperin might play a pivotal role in antiviral immune responses. Interferon-stimulated gene Elsevier Innate antiviral immunity Elsevier poly (I:C) Elsevier RT-qPCR Elsevier Large yellow croaker Elsevier Liu, Cheng oth Zhao, Shujiang oth Guo, Shaoyu oth Shen, Bin oth Enthalten in Elsevier Science Wearne, Travis A. ELSEVIER GABAergic mRNA expression is differentially expressed across the prelimbic and orbitofrontal cortices of rats sensitized to methamphetamine: Relevance to psychosis 2016transfer abstract ontogeny, phylogeny, aging : the official journal of the International Society of Developmental and Comparative Immunology Amsterdam [u.a.] (DE-627)ELV019920881 volume:79 year:2018 pages:59-66 extent:8 https://doi.org/10.1016/j.dci.2017.10.013 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA GBV_ILN_60 44.88 Urologie Nephrologie VZ AR 79 2018 59-66 8 045F 610 |
| language |
English |
| source |
Enthalten in GABAergic mRNA expression is differentially expressed across the prelimbic and orbitofrontal cortices of rats sensitized to methamphetamine: Relevance to psychosis Amsterdam [u.a.] volume:79 year:2018 pages:59-66 extent:8 |
| sourceStr |
Enthalten in GABAergic mRNA expression is differentially expressed across the prelimbic and orbitofrontal cortices of rats sensitized to methamphetamine: Relevance to psychosis Amsterdam [u.a.] volume:79 year:2018 pages:59-66 extent:8 |
| format_phy_str_mv |
Article |
| bklname |
Urologie Nephrologie |
| institution |
findex.gbv.de |
| topic_facet |
Interferon-stimulated gene Innate antiviral immunity poly (I:C) RT-qPCR Large yellow croaker |
| dewey-raw |
610 |
| isfreeaccess_bool |
false |
| container_title |
GABAergic mRNA expression is differentially expressed across the prelimbic and orbitofrontal cortices of rats sensitized to methamphetamine: Relevance to psychosis |
| authorswithroles_txt_mv |
Zhang, Jianshe @@aut@@ Liu, Cheng @@oth@@ Zhao, Shujiang @@oth@@ Guo, Shaoyu @@oth@@ Shen, Bin @@oth@@ |
| publishDateDaySort_date |
2018-01-01T00:00:00Z |
| hierarchy_top_id |
ELV019920881 |
| dewey-sort |
3610 |
| id |
ELV04104424X |
| language_de |
englisch |
| fullrecord |
<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">ELV04104424X</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230625233543.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">180725s2018 xx |||||o 00| ||eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1016/j.dci.2017.10.013</subfield><subfield code="2">doi</subfield></datafield><datafield tag="028" ind1="5" ind2="2"><subfield code="a">GBV00000000000273A.pica</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)ELV04104424X</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(ELSEVIER)S0145-305X(17)30378-6</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="082" ind1="0" ind2=" "><subfield code="a">610</subfield></datafield><datafield tag="082" ind1="0" ind2="4"><subfield code="a">610</subfield><subfield code="q">DE-600</subfield></datafield><datafield tag="082" ind1="0" ind2="4"><subfield code="a">610</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="082" ind1="0" ind2="4"><subfield code="a">610</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">44.88</subfield><subfield code="2">bkl</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Zhang, Jianshe</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Molecular characterization and expression analyses of the Viperin gene in Larimichthys crocea (Family: Sciaenidae)</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2018transfer abstract</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">8</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zzz</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">z</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zu</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">In this study, we sequenced and characterized an interferon-stimulated gene Viperin homologue, LcViperin, from large yellow croaker (Larimichthys crocea). The LcViperin encodes 354 amino acids and contains an N-terminal amphipathic α-helix domain, a radical S-adenosyl-l-methionine (SAM) domain and a highly conserved C-terminal domain. The analyses of LcViperin promoter region revealed nine kinds of putative transcriptional factor binding sites, including five putative ICSBP (IRF-8) binding sites and one putative IRF-1 binding site, indicating that the expression of LcViperin might be induced by the type I IFN response. Phylogenetic analyses based on amino acid sequences showed that the Viperin of large yellow croaker is clustered together with its counterparts from other teleost fishes. The Real-time PCR analyses showed that the LcViperin was found to be ubiquitously expressed in ten examined tissues in large yellow croaker, with predominant expression in peripheral blood, followed by heart and gill. Expression analyses showed that the LcViperin was rapidly and significantly upregulated in vivo after poly (I:C) challenge in peripheral blood, head kidney, spleen and liver tissues. The results indicate that the LcViperin might play a pivotal role in antiviral immune responses.</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">In this study, we sequenced and characterized an interferon-stimulated gene Viperin homologue, LcViperin, from large yellow croaker (Larimichthys crocea). The LcViperin encodes 354 amino acids and contains an N-terminal amphipathic α-helix domain, a radical S-adenosyl-l-methionine (SAM) domain and a highly conserved C-terminal domain. The analyses of LcViperin promoter region revealed nine kinds of putative transcriptional factor binding sites, including five putative ICSBP (IRF-8) binding sites and one putative IRF-1 binding site, indicating that the expression of LcViperin might be induced by the type I IFN response. Phylogenetic analyses based on amino acid sequences showed that the Viperin of large yellow croaker is clustered together with its counterparts from other teleost fishes. The Real-time PCR analyses showed that the LcViperin was found to be ubiquitously expressed in ten examined tissues in large yellow croaker, with predominant expression in peripheral blood, followed by heart and gill. Expression analyses showed that the LcViperin was rapidly and significantly upregulated in vivo after poly (I:C) challenge in peripheral blood, head kidney, spleen and liver tissues. The results indicate that the LcViperin might play a pivotal role in antiviral immune responses.</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Interferon-stimulated gene</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Innate antiviral immunity</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">poly (I:C)</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">RT-qPCR</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Large yellow croaker</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Liu, Cheng</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Zhao, Shujiang</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Guo, Shaoyu</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Shen, Bin</subfield><subfield code="4">oth</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">Enthalten in</subfield><subfield code="n">Elsevier Science</subfield><subfield code="a">Wearne, Travis A. ELSEVIER</subfield><subfield code="t">GABAergic mRNA expression is differentially expressed across the prelimbic and orbitofrontal cortices of rats sensitized to methamphetamine: Relevance to psychosis</subfield><subfield code="d">2016transfer abstract</subfield><subfield code="d">ontogeny, phylogeny, aging : the official journal of the International Society of Developmental and Comparative Immunology</subfield><subfield code="g">Amsterdam [u.a.]</subfield><subfield code="w">(DE-627)ELV019920881</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:79</subfield><subfield code="g">year:2018</subfield><subfield code="g">pages:59-66</subfield><subfield code="g">extent:8</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://doi.org/10.1016/j.dci.2017.10.013</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_U</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ELV</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SYSFLAG_U</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SSG-OLC-PHA</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_60</subfield></datafield><datafield tag="936" ind1="b" ind2="k"><subfield code="a">44.88</subfield><subfield code="j">Urologie</subfield><subfield code="j">Nephrologie</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">79</subfield><subfield code="j">2018</subfield><subfield code="h">59-66</subfield><subfield code="g">8</subfield></datafield><datafield tag="953" ind1=" " ind2=" "><subfield code="2">045F</subfield><subfield code="a">610</subfield></datafield></record></collection>
|
| author |
Zhang, Jianshe |
| spellingShingle |
Zhang, Jianshe ddc 610 bkl 44.88 Elsevier Interferon-stimulated gene Elsevier Innate antiviral immunity Elsevier poly (I:C) Elsevier RT-qPCR Elsevier Large yellow croaker Molecular characterization and expression analyses of the Viperin gene in Larimichthys crocea (Family: Sciaenidae) |
| authorStr |
Zhang, Jianshe |
| ppnlink_with_tag_str_mv |
@@773@@(DE-627)ELV019920881 |
| format |
electronic Article |
| dewey-ones |
610 - Medicine & health |
| delete_txt_mv |
keep |
| author_role |
aut |
| collection |
elsevier |
| remote_str |
true |
| illustrated |
Not Illustrated |
| topic_title |
610 610 DE-600 610 VZ 44.88 bkl Molecular characterization and expression analyses of the Viperin gene in Larimichthys crocea (Family: Sciaenidae) Interferon-stimulated gene Elsevier Innate antiviral immunity Elsevier poly (I:C) Elsevier RT-qPCR Elsevier Large yellow croaker Elsevier |
| topic |
ddc 610 bkl 44.88 Elsevier Interferon-stimulated gene Elsevier Innate antiviral immunity Elsevier poly (I:C) Elsevier RT-qPCR Elsevier Large yellow croaker |
| topic_unstemmed |
ddc 610 bkl 44.88 Elsevier Interferon-stimulated gene Elsevier Innate antiviral immunity Elsevier poly (I:C) Elsevier RT-qPCR Elsevier Large yellow croaker |
| topic_browse |
ddc 610 bkl 44.88 Elsevier Interferon-stimulated gene Elsevier Innate antiviral immunity Elsevier poly (I:C) Elsevier RT-qPCR Elsevier Large yellow croaker |
| format_facet |
Elektronische Aufsätze Aufsätze Elektronische Ressource |
| format_main_str_mv |
Text Zeitschrift/Artikel |
| carriertype_str_mv |
zu |
| author2_variant |
c l cl s z sz s g sg b s bs |
| hierarchy_parent_title |
GABAergic mRNA expression is differentially expressed across the prelimbic and orbitofrontal cortices of rats sensitized to methamphetamine: Relevance to psychosis |
| hierarchy_parent_id |
ELV019920881 |
| dewey-tens |
610 - Medicine & health |
| hierarchy_top_title |
GABAergic mRNA expression is differentially expressed across the prelimbic and orbitofrontal cortices of rats sensitized to methamphetamine: Relevance to psychosis |
| isfreeaccess_txt |
false |
| familylinks_str_mv |
(DE-627)ELV019920881 |
| title |
Molecular characterization and expression analyses of the Viperin gene in Larimichthys crocea (Family: Sciaenidae) |
| ctrlnum |
(DE-627)ELV04104424X (ELSEVIER)S0145-305X(17)30378-6 |
| title_full |
Molecular characterization and expression analyses of the Viperin gene in Larimichthys crocea (Family: Sciaenidae) |
| author_sort |
Zhang, Jianshe |
| journal |
GABAergic mRNA expression is differentially expressed across the prelimbic and orbitofrontal cortices of rats sensitized to methamphetamine: Relevance to psychosis |
| journalStr |
GABAergic mRNA expression is differentially expressed across the prelimbic and orbitofrontal cortices of rats sensitized to methamphetamine: Relevance to psychosis |
| lang_code |
eng |
| isOA_bool |
false |
| dewey-hundreds |
600 - Technology |
| recordtype |
marc |
| publishDateSort |
2018 |
| contenttype_str_mv |
zzz |
| container_start_page |
59 |
| author_browse |
Zhang, Jianshe |
| container_volume |
79 |
| physical |
8 |
| class |
610 610 DE-600 610 VZ 44.88 bkl |
| format_se |
Elektronische Aufsätze |
| author-letter |
Zhang, Jianshe |
| doi_str_mv |
10.1016/j.dci.2017.10.013 |
| dewey-full |
610 |
| title_sort |
molecular characterization and expression analyses of the viperin gene in larimichthys crocea (family: sciaenidae) |
| title_auth |
Molecular characterization and expression analyses of the Viperin gene in Larimichthys crocea (Family: Sciaenidae) |
| abstract |
In this study, we sequenced and characterized an interferon-stimulated gene Viperin homologue, LcViperin, from large yellow croaker (Larimichthys crocea). The LcViperin encodes 354 amino acids and contains an N-terminal amphipathic α-helix domain, a radical S-adenosyl-l-methionine (SAM) domain and a highly conserved C-terminal domain. The analyses of LcViperin promoter region revealed nine kinds of putative transcriptional factor binding sites, including five putative ICSBP (IRF-8) binding sites and one putative IRF-1 binding site, indicating that the expression of LcViperin might be induced by the type I IFN response. Phylogenetic analyses based on amino acid sequences showed that the Viperin of large yellow croaker is clustered together with its counterparts from other teleost fishes. The Real-time PCR analyses showed that the LcViperin was found to be ubiquitously expressed in ten examined tissues in large yellow croaker, with predominant expression in peripheral blood, followed by heart and gill. Expression analyses showed that the LcViperin was rapidly and significantly upregulated in vivo after poly (I:C) challenge in peripheral blood, head kidney, spleen and liver tissues. The results indicate that the LcViperin might play a pivotal role in antiviral immune responses. |
| abstractGer |
In this study, we sequenced and characterized an interferon-stimulated gene Viperin homologue, LcViperin, from large yellow croaker (Larimichthys crocea). The LcViperin encodes 354 amino acids and contains an N-terminal amphipathic α-helix domain, a radical S-adenosyl-l-methionine (SAM) domain and a highly conserved C-terminal domain. The analyses of LcViperin promoter region revealed nine kinds of putative transcriptional factor binding sites, including five putative ICSBP (IRF-8) binding sites and one putative IRF-1 binding site, indicating that the expression of LcViperin might be induced by the type I IFN response. Phylogenetic analyses based on amino acid sequences showed that the Viperin of large yellow croaker is clustered together with its counterparts from other teleost fishes. The Real-time PCR analyses showed that the LcViperin was found to be ubiquitously expressed in ten examined tissues in large yellow croaker, with predominant expression in peripheral blood, followed by heart and gill. Expression analyses showed that the LcViperin was rapidly and significantly upregulated in vivo after poly (I:C) challenge in peripheral blood, head kidney, spleen and liver tissues. The results indicate that the LcViperin might play a pivotal role in antiviral immune responses. |
| abstract_unstemmed |
In this study, we sequenced and characterized an interferon-stimulated gene Viperin homologue, LcViperin, from large yellow croaker (Larimichthys crocea). The LcViperin encodes 354 amino acids and contains an N-terminal amphipathic α-helix domain, a radical S-adenosyl-l-methionine (SAM) domain and a highly conserved C-terminal domain. The analyses of LcViperin promoter region revealed nine kinds of putative transcriptional factor binding sites, including five putative ICSBP (IRF-8) binding sites and one putative IRF-1 binding site, indicating that the expression of LcViperin might be induced by the type I IFN response. Phylogenetic analyses based on amino acid sequences showed that the Viperin of large yellow croaker is clustered together with its counterparts from other teleost fishes. The Real-time PCR analyses showed that the LcViperin was found to be ubiquitously expressed in ten examined tissues in large yellow croaker, with predominant expression in peripheral blood, followed by heart and gill. Expression analyses showed that the LcViperin was rapidly and significantly upregulated in vivo after poly (I:C) challenge in peripheral blood, head kidney, spleen and liver tissues. The results indicate that the LcViperin might play a pivotal role in antiviral immune responses. |
| collection_details |
GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA GBV_ILN_60 |
| title_short |
Molecular characterization and expression analyses of the Viperin gene in Larimichthys crocea (Family: Sciaenidae) |
| url |
https://doi.org/10.1016/j.dci.2017.10.013 |
| remote_bool |
true |
| author2 |
Liu, Cheng Zhao, Shujiang Guo, Shaoyu Shen, Bin |
| author2Str |
Liu, Cheng Zhao, Shujiang Guo, Shaoyu Shen, Bin |
| ppnlink |
ELV019920881 |
| mediatype_str_mv |
z |
| isOA_txt |
false |
| hochschulschrift_bool |
false |
| author2_role |
oth oth oth oth |
| doi_str |
10.1016/j.dci.2017.10.013 |
| up_date |
2024-07-06T19:04:58.543Z |
| _version_ |
1803857636668473344 |
| fullrecord_marcxml |
<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">ELV04104424X</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230625233543.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">180725s2018 xx |||||o 00| ||eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1016/j.dci.2017.10.013</subfield><subfield code="2">doi</subfield></datafield><datafield tag="028" ind1="5" ind2="2"><subfield code="a">GBV00000000000273A.pica</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)ELV04104424X</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(ELSEVIER)S0145-305X(17)30378-6</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="082" ind1="0" ind2=" "><subfield code="a">610</subfield></datafield><datafield tag="082" ind1="0" ind2="4"><subfield code="a">610</subfield><subfield code="q">DE-600</subfield></datafield><datafield tag="082" ind1="0" ind2="4"><subfield code="a">610</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="082" ind1="0" ind2="4"><subfield code="a">610</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">44.88</subfield><subfield code="2">bkl</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Zhang, Jianshe</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Molecular characterization and expression analyses of the Viperin gene in Larimichthys crocea (Family: Sciaenidae)</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2018transfer abstract</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">8</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zzz</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">z</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zu</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">In this study, we sequenced and characterized an interferon-stimulated gene Viperin homologue, LcViperin, from large yellow croaker (Larimichthys crocea). The LcViperin encodes 354 amino acids and contains an N-terminal amphipathic α-helix domain, a radical S-adenosyl-l-methionine (SAM) domain and a highly conserved C-terminal domain. The analyses of LcViperin promoter region revealed nine kinds of putative transcriptional factor binding sites, including five putative ICSBP (IRF-8) binding sites and one putative IRF-1 binding site, indicating that the expression of LcViperin might be induced by the type I IFN response. Phylogenetic analyses based on amino acid sequences showed that the Viperin of large yellow croaker is clustered together with its counterparts from other teleost fishes. The Real-time PCR analyses showed that the LcViperin was found to be ubiquitously expressed in ten examined tissues in large yellow croaker, with predominant expression in peripheral blood, followed by heart and gill. Expression analyses showed that the LcViperin was rapidly and significantly upregulated in vivo after poly (I:C) challenge in peripheral blood, head kidney, spleen and liver tissues. The results indicate that the LcViperin might play a pivotal role in antiviral immune responses.</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">In this study, we sequenced and characterized an interferon-stimulated gene Viperin homologue, LcViperin, from large yellow croaker (Larimichthys crocea). The LcViperin encodes 354 amino acids and contains an N-terminal amphipathic α-helix domain, a radical S-adenosyl-l-methionine (SAM) domain and a highly conserved C-terminal domain. The analyses of LcViperin promoter region revealed nine kinds of putative transcriptional factor binding sites, including five putative ICSBP (IRF-8) binding sites and one putative IRF-1 binding site, indicating that the expression of LcViperin might be induced by the type I IFN response. Phylogenetic analyses based on amino acid sequences showed that the Viperin of large yellow croaker is clustered together with its counterparts from other teleost fishes. The Real-time PCR analyses showed that the LcViperin was found to be ubiquitously expressed in ten examined tissues in large yellow croaker, with predominant expression in peripheral blood, followed by heart and gill. Expression analyses showed that the LcViperin was rapidly and significantly upregulated in vivo after poly (I:C) challenge in peripheral blood, head kidney, spleen and liver tissues. The results indicate that the LcViperin might play a pivotal role in antiviral immune responses.</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Interferon-stimulated gene</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Innate antiviral immunity</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">poly (I:C)</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">RT-qPCR</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Large yellow croaker</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Liu, Cheng</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Zhao, Shujiang</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Guo, Shaoyu</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Shen, Bin</subfield><subfield code="4">oth</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">Enthalten in</subfield><subfield code="n">Elsevier Science</subfield><subfield code="a">Wearne, Travis A. ELSEVIER</subfield><subfield code="t">GABAergic mRNA expression is differentially expressed across the prelimbic and orbitofrontal cortices of rats sensitized to methamphetamine: Relevance to psychosis</subfield><subfield code="d">2016transfer abstract</subfield><subfield code="d">ontogeny, phylogeny, aging : the official journal of the International Society of Developmental and Comparative Immunology</subfield><subfield code="g">Amsterdam [u.a.]</subfield><subfield code="w">(DE-627)ELV019920881</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:79</subfield><subfield code="g">year:2018</subfield><subfield code="g">pages:59-66</subfield><subfield code="g">extent:8</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://doi.org/10.1016/j.dci.2017.10.013</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_U</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ELV</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SYSFLAG_U</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SSG-OLC-PHA</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_60</subfield></datafield><datafield tag="936" ind1="b" ind2="k"><subfield code="a">44.88</subfield><subfield code="j">Urologie</subfield><subfield code="j">Nephrologie</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">79</subfield><subfield code="j">2018</subfield><subfield code="h">59-66</subfield><subfield code="g">8</subfield></datafield><datafield tag="953" ind1=" " ind2=" "><subfield code="2">045F</subfield><subfield code="a">610</subfield></datafield></record></collection>
|
| score |
7.3982267 |