Local Ca2+-ROS Cross Talk Between ER And Mitochondria
Mitochondria form junctions with the sarco/endoplasmic reticulum (SR/ER), which support many cell functions locally including calcium signaling, organellar dynamics and lipid biosynthesis. The SR/ER and mitochondrial membranes also host sources and targets of reactive oxygen species (ROS) but their...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Booth, David M. [verfasserIn] |
|---|
| Format: |
E-Artikel |
|---|---|
| Sprache: |
Englisch |
| Erschienen: |
2017transfer abstract |
|---|
| Übergeordnetes Werk: |
Enthalten in: New organic dyes with varied arylamine donors as effective co-sensitizers for ruthenium complex N719 in dye sensitized solar cells - Wu, Zhi-Sheng ELSEVIER, 2020, the official journal of the Oxygen Society, a constituent member of the International Society for Free Radical Research, New York, NY [u.a.] |
|---|---|
| Übergeordnetes Werk: |
volume:112 ; year:2017 ; pages:10 |
| Links: |
|---|
| DOI / URN: |
10.1016/j.freeradbiomed.2017.10.360 |
|---|
| Katalog-ID: |
ELV04111373X |
|---|
| LEADER | 01000caa a22002652 4500 | ||
|---|---|---|---|
| 001 | ELV04111373X | ||
| 003 | DE-627 | ||
| 005 | 20230625233735.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 180725s2017 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1016/j.freeradbiomed.2017.10.360 |2 doi | |
| 028 | 5 | 2 | |a GBV00000000000059A.pica |
| 035 | |a (DE-627)ELV04111373X | ||
| 035 | |a (ELSEVIER)S0891-5849(17)31143-7 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 082 | 0 | |a 570 |a 610 | |
| 082 | 0 | 4 | |a 570 |q DE-600 |
| 082 | 0 | 4 | |a 610 |q DE-600 |
| 082 | 0 | 4 | |a 620 |q VZ |
| 084 | |a 52.57 |2 bkl | ||
| 084 | |a 53.36 |2 bkl | ||
| 100 | 1 | |a Booth, David M. |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Local Ca2+-ROS Cross Talk Between ER And Mitochondria |
| 264 | 1 | |c 2017transfer abstract | |
| 336 | |a nicht spezifiziert |b zzz |2 rdacontent | ||
| 337 | |a nicht spezifiziert |b z |2 rdamedia | ||
| 338 | |a nicht spezifiziert |b zu |2 rdacarrier | ||
| 520 | |a Mitochondria form junctions with the sarco/endoplasmic reticulum (SR/ER), which support many cell functions locally including calcium signaling, organellar dynamics and lipid biosynthesis. The SR/ER and mitochondrial membranes also host sources and targets of reactive oxygen species (ROS) but their local dynamics and relevance remained elusive because measurement and perturbation of ROS at the organellar interface has proven difficult. We will describe fluorescence based strategies to monitor the ROS fluctuations at the SR/ER-mitochondria interface and present evidence for spatially confined ROS fluctuations in association with calcium signal propagation from ER to the mitochondria and transient mitochondrial depolarizations referred as flickers. We will also offer some clues to the functional significance of the ER-mitochondrial nanodomains in regulating calcium signaling and mitochondrial activities. | ||
| 520 | |a Mitochondria form junctions with the sarco/endoplasmic reticulum (SR/ER), which support many cell functions locally including calcium signaling, organellar dynamics and lipid biosynthesis. The SR/ER and mitochondrial membranes also host sources and targets of reactive oxygen species (ROS) but their local dynamics and relevance remained elusive because measurement and perturbation of ROS at the organellar interface has proven difficult. We will describe fluorescence based strategies to monitor the ROS fluctuations at the SR/ER-mitochondria interface and present evidence for spatially confined ROS fluctuations in association with calcium signal propagation from ER to the mitochondria and transient mitochondrial depolarizations referred as flickers. We will also offer some clues to the functional significance of the ER-mitochondrial nanodomains in regulating calcium signaling and mitochondrial activities. | ||
| 700 | 1 | |a Várnai, Péter |4 oth | |
| 700 | 1 | |a Hajnóczky, György |4 oth | |
| 773 | 0 | 8 | |i Enthalten in |n Elsevier |a Wu, Zhi-Sheng ELSEVIER |t New organic dyes with varied arylamine donors as effective co-sensitizers for ruthenium complex N719 in dye sensitized solar cells |d 2020 |d the official journal of the Oxygen Society, a constituent member of the International Society for Free Radical Research |g New York, NY [u.a.] |w (DE-627)ELV003689417 |
| 773 | 1 | 8 | |g volume:112 |g year:2017 |g pages:10 |
| 856 | 4 | 0 | |u https://doi.org/10.1016/j.freeradbiomed.2017.10.360 |3 Volltext |
| 912 | |a GBV_USEFLAG_U | ||
| 912 | |a GBV_ELV | ||
| 912 | |a SYSFLAG_U | ||
| 936 | b | k | |a 52.57 |j Energiespeicherung |q VZ |
| 936 | b | k | |a 53.36 |j Energiedirektumwandler |j elektrische Energiespeicher |q VZ |
| 951 | |a AR | ||
| 952 | |d 112 |j 2017 |h 10 | ||
| 953 | |2 045F |a 570 | ||
| author_variant |
d m b dm dmb |
|---|---|
| matchkey_str |
boothdavidmvrnaipterhajnczkygyrgy:2017----:oac2ocosakeweead |
| hierarchy_sort_str |
2017transfer abstract |
| bklnumber |
52.57 53.36 |
| publishDate |
2017 |
| allfields |
10.1016/j.freeradbiomed.2017.10.360 doi GBV00000000000059A.pica (DE-627)ELV04111373X (ELSEVIER)S0891-5849(17)31143-7 DE-627 ger DE-627 rakwb eng 570 610 570 DE-600 610 DE-600 620 VZ 52.57 bkl 53.36 bkl Booth, David M. verfasserin aut Local Ca2+-ROS Cross Talk Between ER And Mitochondria 2017transfer abstract nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Mitochondria form junctions with the sarco/endoplasmic reticulum (SR/ER), which support many cell functions locally including calcium signaling, organellar dynamics and lipid biosynthesis. The SR/ER and mitochondrial membranes also host sources and targets of reactive oxygen species (ROS) but their local dynamics and relevance remained elusive because measurement and perturbation of ROS at the organellar interface has proven difficult. We will describe fluorescence based strategies to monitor the ROS fluctuations at the SR/ER-mitochondria interface and present evidence for spatially confined ROS fluctuations in association with calcium signal propagation from ER to the mitochondria and transient mitochondrial depolarizations referred as flickers. We will also offer some clues to the functional significance of the ER-mitochondrial nanodomains in regulating calcium signaling and mitochondrial activities. Mitochondria form junctions with the sarco/endoplasmic reticulum (SR/ER), which support many cell functions locally including calcium signaling, organellar dynamics and lipid biosynthesis. The SR/ER and mitochondrial membranes also host sources and targets of reactive oxygen species (ROS) but their local dynamics and relevance remained elusive because measurement and perturbation of ROS at the organellar interface has proven difficult. We will describe fluorescence based strategies to monitor the ROS fluctuations at the SR/ER-mitochondria interface and present evidence for spatially confined ROS fluctuations in association with calcium signal propagation from ER to the mitochondria and transient mitochondrial depolarizations referred as flickers. We will also offer some clues to the functional significance of the ER-mitochondrial nanodomains in regulating calcium signaling and mitochondrial activities. Várnai, Péter oth Hajnóczky, György oth Enthalten in Elsevier Wu, Zhi-Sheng ELSEVIER New organic dyes with varied arylamine donors as effective co-sensitizers for ruthenium complex N719 in dye sensitized solar cells 2020 the official journal of the Oxygen Society, a constituent member of the International Society for Free Radical Research New York, NY [u.a.] (DE-627)ELV003689417 volume:112 year:2017 pages:10 https://doi.org/10.1016/j.freeradbiomed.2017.10.360 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U 52.57 Energiespeicherung VZ 53.36 Energiedirektumwandler elektrische Energiespeicher VZ AR 112 2017 10 045F 570 |
| spelling |
10.1016/j.freeradbiomed.2017.10.360 doi GBV00000000000059A.pica (DE-627)ELV04111373X (ELSEVIER)S0891-5849(17)31143-7 DE-627 ger DE-627 rakwb eng 570 610 570 DE-600 610 DE-600 620 VZ 52.57 bkl 53.36 bkl Booth, David M. verfasserin aut Local Ca2+-ROS Cross Talk Between ER And Mitochondria 2017transfer abstract nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Mitochondria form junctions with the sarco/endoplasmic reticulum (SR/ER), which support many cell functions locally including calcium signaling, organellar dynamics and lipid biosynthesis. The SR/ER and mitochondrial membranes also host sources and targets of reactive oxygen species (ROS) but their local dynamics and relevance remained elusive because measurement and perturbation of ROS at the organellar interface has proven difficult. We will describe fluorescence based strategies to monitor the ROS fluctuations at the SR/ER-mitochondria interface and present evidence for spatially confined ROS fluctuations in association with calcium signal propagation from ER to the mitochondria and transient mitochondrial depolarizations referred as flickers. We will also offer some clues to the functional significance of the ER-mitochondrial nanodomains in regulating calcium signaling and mitochondrial activities. Mitochondria form junctions with the sarco/endoplasmic reticulum (SR/ER), which support many cell functions locally including calcium signaling, organellar dynamics and lipid biosynthesis. The SR/ER and mitochondrial membranes also host sources and targets of reactive oxygen species (ROS) but their local dynamics and relevance remained elusive because measurement and perturbation of ROS at the organellar interface has proven difficult. We will describe fluorescence based strategies to monitor the ROS fluctuations at the SR/ER-mitochondria interface and present evidence for spatially confined ROS fluctuations in association with calcium signal propagation from ER to the mitochondria and transient mitochondrial depolarizations referred as flickers. We will also offer some clues to the functional significance of the ER-mitochondrial nanodomains in regulating calcium signaling and mitochondrial activities. Várnai, Péter oth Hajnóczky, György oth Enthalten in Elsevier Wu, Zhi-Sheng ELSEVIER New organic dyes with varied arylamine donors as effective co-sensitizers for ruthenium complex N719 in dye sensitized solar cells 2020 the official journal of the Oxygen Society, a constituent member of the International Society for Free Radical Research New York, NY [u.a.] (DE-627)ELV003689417 volume:112 year:2017 pages:10 https://doi.org/10.1016/j.freeradbiomed.2017.10.360 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U 52.57 Energiespeicherung VZ 53.36 Energiedirektumwandler elektrische Energiespeicher VZ AR 112 2017 10 045F 570 |
| allfields_unstemmed |
10.1016/j.freeradbiomed.2017.10.360 doi GBV00000000000059A.pica (DE-627)ELV04111373X (ELSEVIER)S0891-5849(17)31143-7 DE-627 ger DE-627 rakwb eng 570 610 570 DE-600 610 DE-600 620 VZ 52.57 bkl 53.36 bkl Booth, David M. verfasserin aut Local Ca2+-ROS Cross Talk Between ER And Mitochondria 2017transfer abstract nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Mitochondria form junctions with the sarco/endoplasmic reticulum (SR/ER), which support many cell functions locally including calcium signaling, organellar dynamics and lipid biosynthesis. The SR/ER and mitochondrial membranes also host sources and targets of reactive oxygen species (ROS) but their local dynamics and relevance remained elusive because measurement and perturbation of ROS at the organellar interface has proven difficult. We will describe fluorescence based strategies to monitor the ROS fluctuations at the SR/ER-mitochondria interface and present evidence for spatially confined ROS fluctuations in association with calcium signal propagation from ER to the mitochondria and transient mitochondrial depolarizations referred as flickers. We will also offer some clues to the functional significance of the ER-mitochondrial nanodomains in regulating calcium signaling and mitochondrial activities. Mitochondria form junctions with the sarco/endoplasmic reticulum (SR/ER), which support many cell functions locally including calcium signaling, organellar dynamics and lipid biosynthesis. The SR/ER and mitochondrial membranes also host sources and targets of reactive oxygen species (ROS) but their local dynamics and relevance remained elusive because measurement and perturbation of ROS at the organellar interface has proven difficult. We will describe fluorescence based strategies to monitor the ROS fluctuations at the SR/ER-mitochondria interface and present evidence for spatially confined ROS fluctuations in association with calcium signal propagation from ER to the mitochondria and transient mitochondrial depolarizations referred as flickers. We will also offer some clues to the functional significance of the ER-mitochondrial nanodomains in regulating calcium signaling and mitochondrial activities. Várnai, Péter oth Hajnóczky, György oth Enthalten in Elsevier Wu, Zhi-Sheng ELSEVIER New organic dyes with varied arylamine donors as effective co-sensitizers for ruthenium complex N719 in dye sensitized solar cells 2020 the official journal of the Oxygen Society, a constituent member of the International Society for Free Radical Research New York, NY [u.a.] (DE-627)ELV003689417 volume:112 year:2017 pages:10 https://doi.org/10.1016/j.freeradbiomed.2017.10.360 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U 52.57 Energiespeicherung VZ 53.36 Energiedirektumwandler elektrische Energiespeicher VZ AR 112 2017 10 045F 570 |
| allfieldsGer |
10.1016/j.freeradbiomed.2017.10.360 doi GBV00000000000059A.pica (DE-627)ELV04111373X (ELSEVIER)S0891-5849(17)31143-7 DE-627 ger DE-627 rakwb eng 570 610 570 DE-600 610 DE-600 620 VZ 52.57 bkl 53.36 bkl Booth, David M. verfasserin aut Local Ca2+-ROS Cross Talk Between ER And Mitochondria 2017transfer abstract nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Mitochondria form junctions with the sarco/endoplasmic reticulum (SR/ER), which support many cell functions locally including calcium signaling, organellar dynamics and lipid biosynthesis. The SR/ER and mitochondrial membranes also host sources and targets of reactive oxygen species (ROS) but their local dynamics and relevance remained elusive because measurement and perturbation of ROS at the organellar interface has proven difficult. We will describe fluorescence based strategies to monitor the ROS fluctuations at the SR/ER-mitochondria interface and present evidence for spatially confined ROS fluctuations in association with calcium signal propagation from ER to the mitochondria and transient mitochondrial depolarizations referred as flickers. We will also offer some clues to the functional significance of the ER-mitochondrial nanodomains in regulating calcium signaling and mitochondrial activities. Mitochondria form junctions with the sarco/endoplasmic reticulum (SR/ER), which support many cell functions locally including calcium signaling, organellar dynamics and lipid biosynthesis. The SR/ER and mitochondrial membranes also host sources and targets of reactive oxygen species (ROS) but their local dynamics and relevance remained elusive because measurement and perturbation of ROS at the organellar interface has proven difficult. We will describe fluorescence based strategies to monitor the ROS fluctuations at the SR/ER-mitochondria interface and present evidence for spatially confined ROS fluctuations in association with calcium signal propagation from ER to the mitochondria and transient mitochondrial depolarizations referred as flickers. We will also offer some clues to the functional significance of the ER-mitochondrial nanodomains in regulating calcium signaling and mitochondrial activities. Várnai, Péter oth Hajnóczky, György oth Enthalten in Elsevier Wu, Zhi-Sheng ELSEVIER New organic dyes with varied arylamine donors as effective co-sensitizers for ruthenium complex N719 in dye sensitized solar cells 2020 the official journal of the Oxygen Society, a constituent member of the International Society for Free Radical Research New York, NY [u.a.] (DE-627)ELV003689417 volume:112 year:2017 pages:10 https://doi.org/10.1016/j.freeradbiomed.2017.10.360 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U 52.57 Energiespeicherung VZ 53.36 Energiedirektumwandler elektrische Energiespeicher VZ AR 112 2017 10 045F 570 |
| allfieldsSound |
10.1016/j.freeradbiomed.2017.10.360 doi GBV00000000000059A.pica (DE-627)ELV04111373X (ELSEVIER)S0891-5849(17)31143-7 DE-627 ger DE-627 rakwb eng 570 610 570 DE-600 610 DE-600 620 VZ 52.57 bkl 53.36 bkl Booth, David M. verfasserin aut Local Ca2+-ROS Cross Talk Between ER And Mitochondria 2017transfer abstract nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Mitochondria form junctions with the sarco/endoplasmic reticulum (SR/ER), which support many cell functions locally including calcium signaling, organellar dynamics and lipid biosynthesis. The SR/ER and mitochondrial membranes also host sources and targets of reactive oxygen species (ROS) but their local dynamics and relevance remained elusive because measurement and perturbation of ROS at the organellar interface has proven difficult. We will describe fluorescence based strategies to monitor the ROS fluctuations at the SR/ER-mitochondria interface and present evidence for spatially confined ROS fluctuations in association with calcium signal propagation from ER to the mitochondria and transient mitochondrial depolarizations referred as flickers. We will also offer some clues to the functional significance of the ER-mitochondrial nanodomains in regulating calcium signaling and mitochondrial activities. Mitochondria form junctions with the sarco/endoplasmic reticulum (SR/ER), which support many cell functions locally including calcium signaling, organellar dynamics and lipid biosynthesis. The SR/ER and mitochondrial membranes also host sources and targets of reactive oxygen species (ROS) but their local dynamics and relevance remained elusive because measurement and perturbation of ROS at the organellar interface has proven difficult. We will describe fluorescence based strategies to monitor the ROS fluctuations at the SR/ER-mitochondria interface and present evidence for spatially confined ROS fluctuations in association with calcium signal propagation from ER to the mitochondria and transient mitochondrial depolarizations referred as flickers. We will also offer some clues to the functional significance of the ER-mitochondrial nanodomains in regulating calcium signaling and mitochondrial activities. Várnai, Péter oth Hajnóczky, György oth Enthalten in Elsevier Wu, Zhi-Sheng ELSEVIER New organic dyes with varied arylamine donors as effective co-sensitizers for ruthenium complex N719 in dye sensitized solar cells 2020 the official journal of the Oxygen Society, a constituent member of the International Society for Free Radical Research New York, NY [u.a.] (DE-627)ELV003689417 volume:112 year:2017 pages:10 https://doi.org/10.1016/j.freeradbiomed.2017.10.360 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U 52.57 Energiespeicherung VZ 53.36 Energiedirektumwandler elektrische Energiespeicher VZ AR 112 2017 10 045F 570 |
| language |
English |
| source |
Enthalten in New organic dyes with varied arylamine donors as effective co-sensitizers for ruthenium complex N719 in dye sensitized solar cells New York, NY [u.a.] volume:112 year:2017 pages:10 |
| sourceStr |
Enthalten in New organic dyes with varied arylamine donors as effective co-sensitizers for ruthenium complex N719 in dye sensitized solar cells New York, NY [u.a.] volume:112 year:2017 pages:10 |
| format_phy_str_mv |
Article |
| bklname |
Energiespeicherung Energiedirektumwandler elektrische Energiespeicher |
| institution |
findex.gbv.de |
| dewey-raw |
570 |
| isfreeaccess_bool |
false |
| container_title |
New organic dyes with varied arylamine donors as effective co-sensitizers for ruthenium complex N719 in dye sensitized solar cells |
| authorswithroles_txt_mv |
Booth, David M. @@aut@@ Várnai, Péter @@oth@@ Hajnóczky, György @@oth@@ |
| publishDateDaySort_date |
2017-01-01T00:00:00Z |
| hierarchy_top_id |
ELV003689417 |
| dewey-sort |
3570 |
| id |
ELV04111373X |
| language_de |
englisch |
| fullrecord |
<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">ELV04111373X</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230625233735.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">180725s2017 xx |||||o 00| ||eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1016/j.freeradbiomed.2017.10.360</subfield><subfield code="2">doi</subfield></datafield><datafield tag="028" ind1="5" ind2="2"><subfield code="a">GBV00000000000059A.pica</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)ELV04111373X</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(ELSEVIER)S0891-5849(17)31143-7</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="082" ind1="0" ind2=" "><subfield code="a">570</subfield><subfield code="a">610</subfield></datafield><datafield tag="082" ind1="0" ind2="4"><subfield code="a">570</subfield><subfield code="q">DE-600</subfield></datafield><datafield tag="082" ind1="0" ind2="4"><subfield code="a">610</subfield><subfield code="q">DE-600</subfield></datafield><datafield tag="082" ind1="0" ind2="4"><subfield code="a">620</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">52.57</subfield><subfield code="2">bkl</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">53.36</subfield><subfield code="2">bkl</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Booth, David M.</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Local Ca2+-ROS Cross Talk Between ER And Mitochondria</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2017transfer abstract</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zzz</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">z</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zu</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Mitochondria form junctions with the sarco/endoplasmic reticulum (SR/ER), which support many cell functions locally including calcium signaling, organellar dynamics and lipid biosynthesis. The SR/ER and mitochondrial membranes also host sources and targets of reactive oxygen species (ROS) but their local dynamics and relevance remained elusive because measurement and perturbation of ROS at the organellar interface has proven difficult. We will describe fluorescence based strategies to monitor the ROS fluctuations at the SR/ER-mitochondria interface and present evidence for spatially confined ROS fluctuations in association with calcium signal propagation from ER to the mitochondria and transient mitochondrial depolarizations referred as flickers. We will also offer some clues to the functional significance of the ER-mitochondrial nanodomains in regulating calcium signaling and mitochondrial activities.</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Mitochondria form junctions with the sarco/endoplasmic reticulum (SR/ER), which support many cell functions locally including calcium signaling, organellar dynamics and lipid biosynthesis. The SR/ER and mitochondrial membranes also host sources and targets of reactive oxygen species (ROS) but their local dynamics and relevance remained elusive because measurement and perturbation of ROS at the organellar interface has proven difficult. We will describe fluorescence based strategies to monitor the ROS fluctuations at the SR/ER-mitochondria interface and present evidence for spatially confined ROS fluctuations in association with calcium signal propagation from ER to the mitochondria and transient mitochondrial depolarizations referred as flickers. We will also offer some clues to the functional significance of the ER-mitochondrial nanodomains in regulating calcium signaling and mitochondrial activities.</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Várnai, Péter</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Hajnóczky, György</subfield><subfield code="4">oth</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">Enthalten in</subfield><subfield code="n">Elsevier</subfield><subfield code="a">Wu, Zhi-Sheng ELSEVIER</subfield><subfield code="t">New organic dyes with varied arylamine donors as effective co-sensitizers for ruthenium complex N719 in dye sensitized solar cells</subfield><subfield code="d">2020</subfield><subfield code="d">the official journal of the Oxygen Society, a constituent member of the International Society for Free Radical Research</subfield><subfield code="g">New York, NY [u.a.]</subfield><subfield code="w">(DE-627)ELV003689417</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:112</subfield><subfield code="g">year:2017</subfield><subfield code="g">pages:10</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://doi.org/10.1016/j.freeradbiomed.2017.10.360</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_U</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ELV</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SYSFLAG_U</subfield></datafield><datafield tag="936" ind1="b" ind2="k"><subfield code="a">52.57</subfield><subfield code="j">Energiespeicherung</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="936" ind1="b" ind2="k"><subfield code="a">53.36</subfield><subfield code="j">Energiedirektumwandler</subfield><subfield code="j">elektrische Energiespeicher</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">112</subfield><subfield code="j">2017</subfield><subfield code="h">10</subfield></datafield><datafield tag="953" ind1=" " ind2=" "><subfield code="2">045F</subfield><subfield code="a">570</subfield></datafield></record></collection>
|
| author |
Booth, David M. |
| spellingShingle |
Booth, David M. ddc 570 ddc 610 ddc 620 bkl 52.57 bkl 53.36 Local Ca2+-ROS Cross Talk Between ER And Mitochondria |
| authorStr |
Booth, David M. |
| ppnlink_with_tag_str_mv |
@@773@@(DE-627)ELV003689417 |
| format |
electronic Article |
| dewey-ones |
570 - Life sciences; biology 610 - Medicine & health 620 - Engineering & allied operations |
| delete_txt_mv |
keep |
| author_role |
aut |
| collection |
elsevier |
| remote_str |
true |
| illustrated |
Not Illustrated |
| topic_title |
570 610 570 DE-600 610 DE-600 620 VZ 52.57 bkl 53.36 bkl Local Ca2+-ROS Cross Talk Between ER And Mitochondria |
| topic |
ddc 570 ddc 610 ddc 620 bkl 52.57 bkl 53.36 |
| topic_unstemmed |
ddc 570 ddc 610 ddc 620 bkl 52.57 bkl 53.36 |
| topic_browse |
ddc 570 ddc 610 ddc 620 bkl 52.57 bkl 53.36 |
| format_facet |
Elektronische Aufsätze Aufsätze Elektronische Ressource |
| format_main_str_mv |
Text Zeitschrift/Artikel |
| carriertype_str_mv |
zu |
| author2_variant |
p v pv g h gh |
| hierarchy_parent_title |
New organic dyes with varied arylamine donors as effective co-sensitizers for ruthenium complex N719 in dye sensitized solar cells |
| hierarchy_parent_id |
ELV003689417 |
| dewey-tens |
570 - Life sciences; biology 610 - Medicine & health 620 - Engineering |
| hierarchy_top_title |
New organic dyes with varied arylamine donors as effective co-sensitizers for ruthenium complex N719 in dye sensitized solar cells |
| isfreeaccess_txt |
false |
| familylinks_str_mv |
(DE-627)ELV003689417 |
| title |
Local Ca2+-ROS Cross Talk Between ER And Mitochondria |
| ctrlnum |
(DE-627)ELV04111373X (ELSEVIER)S0891-5849(17)31143-7 |
| title_full |
Local Ca2+-ROS Cross Talk Between ER And Mitochondria |
| author_sort |
Booth, David M. |
| journal |
New organic dyes with varied arylamine donors as effective co-sensitizers for ruthenium complex N719 in dye sensitized solar cells |
| journalStr |
New organic dyes with varied arylamine donors as effective co-sensitizers for ruthenium complex N719 in dye sensitized solar cells |
| lang_code |
eng |
| isOA_bool |
false |
| dewey-hundreds |
500 - Science 600 - Technology |
| recordtype |
marc |
| publishDateSort |
2017 |
| contenttype_str_mv |
zzz |
| container_start_page |
10 |
| author_browse |
Booth, David M. |
| container_volume |
112 |
| class |
570 610 570 DE-600 610 DE-600 620 VZ 52.57 bkl 53.36 bkl |
| format_se |
Elektronische Aufsätze |
| author-letter |
Booth, David M. |
| doi_str_mv |
10.1016/j.freeradbiomed.2017.10.360 |
| dewey-full |
570 610 620 |
| title_sort |
local ca2+-ros cross talk between er and mitochondria |
| title_auth |
Local Ca2+-ROS Cross Talk Between ER And Mitochondria |
| abstract |
Mitochondria form junctions with the sarco/endoplasmic reticulum (SR/ER), which support many cell functions locally including calcium signaling, organellar dynamics and lipid biosynthesis. The SR/ER and mitochondrial membranes also host sources and targets of reactive oxygen species (ROS) but their local dynamics and relevance remained elusive because measurement and perturbation of ROS at the organellar interface has proven difficult. We will describe fluorescence based strategies to monitor the ROS fluctuations at the SR/ER-mitochondria interface and present evidence for spatially confined ROS fluctuations in association with calcium signal propagation from ER to the mitochondria and transient mitochondrial depolarizations referred as flickers. We will also offer some clues to the functional significance of the ER-mitochondrial nanodomains in regulating calcium signaling and mitochondrial activities. |
| abstractGer |
Mitochondria form junctions with the sarco/endoplasmic reticulum (SR/ER), which support many cell functions locally including calcium signaling, organellar dynamics and lipid biosynthesis. The SR/ER and mitochondrial membranes also host sources and targets of reactive oxygen species (ROS) but their local dynamics and relevance remained elusive because measurement and perturbation of ROS at the organellar interface has proven difficult. We will describe fluorescence based strategies to monitor the ROS fluctuations at the SR/ER-mitochondria interface and present evidence for spatially confined ROS fluctuations in association with calcium signal propagation from ER to the mitochondria and transient mitochondrial depolarizations referred as flickers. We will also offer some clues to the functional significance of the ER-mitochondrial nanodomains in regulating calcium signaling and mitochondrial activities. |
| abstract_unstemmed |
Mitochondria form junctions with the sarco/endoplasmic reticulum (SR/ER), which support many cell functions locally including calcium signaling, organellar dynamics and lipid biosynthesis. The SR/ER and mitochondrial membranes also host sources and targets of reactive oxygen species (ROS) but their local dynamics and relevance remained elusive because measurement and perturbation of ROS at the organellar interface has proven difficult. We will describe fluorescence based strategies to monitor the ROS fluctuations at the SR/ER-mitochondria interface and present evidence for spatially confined ROS fluctuations in association with calcium signal propagation from ER to the mitochondria and transient mitochondrial depolarizations referred as flickers. We will also offer some clues to the functional significance of the ER-mitochondrial nanodomains in regulating calcium signaling and mitochondrial activities. |
| collection_details |
GBV_USEFLAG_U GBV_ELV SYSFLAG_U |
| title_short |
Local Ca2+-ROS Cross Talk Between ER And Mitochondria |
| url |
https://doi.org/10.1016/j.freeradbiomed.2017.10.360 |
| remote_bool |
true |
| author2 |
Várnai, Péter Hajnóczky, György |
| author2Str |
Várnai, Péter Hajnóczky, György |
| ppnlink |
ELV003689417 |
| mediatype_str_mv |
z |
| isOA_txt |
false |
| hochschulschrift_bool |
false |
| author2_role |
oth oth |
| doi_str |
10.1016/j.freeradbiomed.2017.10.360 |
| up_date |
2024-07-06T19:15:51.215Z |
| _version_ |
1803858321044668416 |
| fullrecord_marcxml |
<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">ELV04111373X</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230625233735.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">180725s2017 xx |||||o 00| ||eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1016/j.freeradbiomed.2017.10.360</subfield><subfield code="2">doi</subfield></datafield><datafield tag="028" ind1="5" ind2="2"><subfield code="a">GBV00000000000059A.pica</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)ELV04111373X</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(ELSEVIER)S0891-5849(17)31143-7</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="082" ind1="0" ind2=" "><subfield code="a">570</subfield><subfield code="a">610</subfield></datafield><datafield tag="082" ind1="0" ind2="4"><subfield code="a">570</subfield><subfield code="q">DE-600</subfield></datafield><datafield tag="082" ind1="0" ind2="4"><subfield code="a">610</subfield><subfield code="q">DE-600</subfield></datafield><datafield tag="082" ind1="0" ind2="4"><subfield code="a">620</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">52.57</subfield><subfield code="2">bkl</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">53.36</subfield><subfield code="2">bkl</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Booth, David M.</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Local Ca2+-ROS Cross Talk Between ER And Mitochondria</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2017transfer abstract</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zzz</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">z</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zu</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Mitochondria form junctions with the sarco/endoplasmic reticulum (SR/ER), which support many cell functions locally including calcium signaling, organellar dynamics and lipid biosynthesis. The SR/ER and mitochondrial membranes also host sources and targets of reactive oxygen species (ROS) but their local dynamics and relevance remained elusive because measurement and perturbation of ROS at the organellar interface has proven difficult. We will describe fluorescence based strategies to monitor the ROS fluctuations at the SR/ER-mitochondria interface and present evidence for spatially confined ROS fluctuations in association with calcium signal propagation from ER to the mitochondria and transient mitochondrial depolarizations referred as flickers. We will also offer some clues to the functional significance of the ER-mitochondrial nanodomains in regulating calcium signaling and mitochondrial activities.</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Mitochondria form junctions with the sarco/endoplasmic reticulum (SR/ER), which support many cell functions locally including calcium signaling, organellar dynamics and lipid biosynthesis. The SR/ER and mitochondrial membranes also host sources and targets of reactive oxygen species (ROS) but their local dynamics and relevance remained elusive because measurement and perturbation of ROS at the organellar interface has proven difficult. We will describe fluorescence based strategies to monitor the ROS fluctuations at the SR/ER-mitochondria interface and present evidence for spatially confined ROS fluctuations in association with calcium signal propagation from ER to the mitochondria and transient mitochondrial depolarizations referred as flickers. We will also offer some clues to the functional significance of the ER-mitochondrial nanodomains in regulating calcium signaling and mitochondrial activities.</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Várnai, Péter</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Hajnóczky, György</subfield><subfield code="4">oth</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">Enthalten in</subfield><subfield code="n">Elsevier</subfield><subfield code="a">Wu, Zhi-Sheng ELSEVIER</subfield><subfield code="t">New organic dyes with varied arylamine donors as effective co-sensitizers for ruthenium complex N719 in dye sensitized solar cells</subfield><subfield code="d">2020</subfield><subfield code="d">the official journal of the Oxygen Society, a constituent member of the International Society for Free Radical Research</subfield><subfield code="g">New York, NY [u.a.]</subfield><subfield code="w">(DE-627)ELV003689417</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:112</subfield><subfield code="g">year:2017</subfield><subfield code="g">pages:10</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://doi.org/10.1016/j.freeradbiomed.2017.10.360</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_U</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ELV</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SYSFLAG_U</subfield></datafield><datafield tag="936" ind1="b" ind2="k"><subfield code="a">52.57</subfield><subfield code="j">Energiespeicherung</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="936" ind1="b" ind2="k"><subfield code="a">53.36</subfield><subfield code="j">Energiedirektumwandler</subfield><subfield code="j">elektrische Energiespeicher</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">112</subfield><subfield code="j">2017</subfield><subfield code="h">10</subfield></datafield><datafield tag="953" ind1=" " ind2=" "><subfield code="2">045F</subfield><subfield code="a">570</subfield></datafield></record></collection>
|
| score |
7.4019346 |