ESC-derived thymic epithelial cells expressing MOG prevents EAE by central and peripheral tolerance mechanisms

• Transplantation of MOG/mESC-TEPs prevents the development of EAE in mice. • MOG-specific autoreactive T cells are deleted in MOG/mESC-TEP-transplanted mice. • MOG-specific Tregs were generated in MOG/mESC-TEP-transplanted mice.

Gespeichert in:
Autor*in:

Su, Min [verfasserIn]

Lin, Yujun

Cui, Cheng

Tian, Xiaohong

Lu, Xiuling

He, Zhixu

Lai, Laijun

Format:

E-Artikel

Sprache:

Englisch

Erschienen:

2017

Schlagwörter:

TCR

MOG

MS

TECs

Tregs

EAE

LFB

DN

mESCs

DP

i.t.

AP

H&E

TEPs

B6

BSI

SP

ESCs

Umfang:

8

Übergeordnetes Werk:

Enthalten in: Modified Kuramoto model with inverse-square law coupling and spatial time delay - Lee, Hae Seong ELSEVIER, 2021, Orlando, Fla

Übergeordnetes Werk:

volume:322 ; year:2017 ; pages:84-91 ; extent:8

Links:

Volltext

DOI / URN:

10.1016/j.cellimm.2017.10.007

Katalog-ID:

ELV041389549

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