Improving the selectivity and sensitivity for quantifying 8-α-hydroxy-mutilin in rabbit tissues by using basic mobile phases and negative ionization
• Identified true MRM transition for 8-α-hydroxy-mutilin for the first time. • Basic mobile phase facilitated ionization and formation of product ions. • Significant improvement of selectivity and sensitivity. • Successful application to two GLP tissue residue depletion studies in rabbits.
Autor*in: |
Tan, Aimin [verfasserIn] |
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E-Artikel |
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Sprache: |
Englisch |
Erschienen: |
2018 |
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Schlagwörter: |
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Umfang: |
7 |
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Übergeordnetes Werk: |
Enthalten in: Brain microstructure and morphology of very preterm-born infants at term equivalent age: Associations with motor and cognitive outcomes at 1 and 2 years - Pannek, Kerstin ELSEVIER, 2020, New York, NY [u.a.] |
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Übergeordnetes Werk: |
volume:1072 ; year:2018 ; day:1 ; month:01 ; pages:142-148 ; extent:7 |
Links: |
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DOI / URN: |
10.1016/j.jchromb.2017.11.008 |
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Improving the selectivity and sensitivity for quantifying 8-α-hydroxy-mutilin in rabbit tissues by using basic mobile phases and negative ionization |
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• Identified true MRM transition for 8-α-hydroxy-mutilin for the first time. • Basic mobile phase facilitated ionization and formation of product ions. • Significant improvement of selectivity and sensitivity. • Successful application to two GLP tissue residue depletion studies in rabbits. |
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• Identified true MRM transition for 8-α-hydroxy-mutilin for the first time. • Basic mobile phase facilitated ionization and formation of product ions. • Significant improvement of selectivity and sensitivity. • Successful application to two GLP tissue residue depletion studies in rabbits. |
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