Improving the selectivity and sensitivity for quantifying 8-α-hydroxy-mutilin in rabbit tissues by using basic mobile phases and negative ionization

• Identified true MRM transition for 8-α-hydroxy-mutilin for the first time. • Basic mobile phase facilitated ionization and formation of product ions. • Significant improvement of selectivity and sensitivity. • Successful application to two GLP tissue residue depletion studies in rabbits.

Gespeichert in:
Autor*in:

Tan, Aimin [verfasserIn]

Gu, Guifen

Gui, Xuan

Wu, Yanxin

Bolger, Gordon

Licollari, Albert

Fanaras, John C.

Format:

E-Artikel

Sprache:

Englisch

Erschienen:

2018

Schlagwörter:

Tiamulin

Tissue

8-α-hydroxy-mutilin

LC–MS

Rabbit

Umfang:

7

Übergeordnetes Werk:

Enthalten in: Brain microstructure and morphology of very preterm-born infants at term equivalent age: Associations with motor and cognitive outcomes at 1 and 2 years - Pannek, Kerstin ELSEVIER, 2020, New York, NY [u.a.]

Übergeordnetes Werk:

volume:1072 ; year:2018 ; day:1 ; month:01 ; pages:142-148 ; extent:7

Links:

Volltext

DOI / URN:

10.1016/j.jchromb.2017.11.008

Katalog-ID:

ELV041508394

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