Maturation of effect size during enrollment of prospective randomized trials
Randomized clinical trials are powered by calculating the minimum sample size required to achieve statistical significance, given an estimated effect size (ES). The ES is the raw difference between two treatment arms. ES quantifies the actual magnitude of clinical differences between cohorts and is...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Poola, Ashwini S. [verfasserIn] |
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E-Artikel |
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Englisch |
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2018transfer abstract |
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5 |
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Enthalten in: Iatrogenic pneumothorax during hypoglossal nerve stimulator implantation - Arteaga, Alberto A. ELSEVIER, 2018, JSR : clinical and laboratory investigation : official publication of the Association for Academic Surgery : official publication of the Association of Veterans Administration Surgeons, Orlando, Fla |
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| Übergeordnetes Werk: |
volume:223 ; year:2018 ; pages:34-38 ; extent:5 |
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| DOI / URN: |
10.1016/j.jss.2017.06.082 |
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| 520 | |a Randomized clinical trials are powered by calculating the minimum sample size required to achieve statistical significance, given an estimated effect size (ES). The ES is the raw difference between two treatment arms. ES quantifies the actual magnitude of clinical differences between cohorts and is usually reflective of the true meaning of the trial, regardless of statistical significance. Under a fixed protocol, we hypothesize that the ES may be attained at a smaller sample than predesigned. To investigate patterns of ES during enrollment, we analyzed completed trials that were completed at our institution. | ||
| 520 | |a Randomized clinical trials are powered by calculating the minimum sample size required to achieve statistical significance, given an estimated effect size (ES). The ES is the raw difference between two treatment arms. ES quantifies the actual magnitude of clinical differences between cohorts and is usually reflective of the true meaning of the trial, regardless of statistical significance. Under a fixed protocol, we hypothesize that the ES may be attained at a smaller sample than predesigned. To investigate patterns of ES during enrollment, we analyzed completed trials that were completed at our institution. | ||
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10.1016/j.jss.2017.06.082 doi GBV00000000000268A.pica (DE-627)ELV041892380 (ELSEVIER)S0022-4804(17)30457-2 DE-627 ger DE-627 rakwb eng 610 610 DE-600 610 VZ 44.94 bkl Poola, Ashwini S. verfasserin aut Maturation of effect size during enrollment of prospective randomized trials 2018transfer abstract 5 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Randomized clinical trials are powered by calculating the minimum sample size required to achieve statistical significance, given an estimated effect size (ES). The ES is the raw difference between two treatment arms. ES quantifies the actual magnitude of clinical differences between cohorts and is usually reflective of the true meaning of the trial, regardless of statistical significance. Under a fixed protocol, we hypothesize that the ES may be attained at a smaller sample than predesigned. To investigate patterns of ES during enrollment, we analyzed completed trials that were completed at our institution. Randomized clinical trials are powered by calculating the minimum sample size required to achieve statistical significance, given an estimated effect size (ES). The ES is the raw difference between two treatment arms. ES quantifies the actual magnitude of clinical differences between cohorts and is usually reflective of the true meaning of the trial, regardless of statistical significance. Under a fixed protocol, we hypothesize that the ES may be attained at a smaller sample than predesigned. To investigate patterns of ES during enrollment, we analyzed completed trials that were completed at our institution. Sample size Elsevier Effect size Elsevier Randomized control trial Elsevier Oyetunji, Tolulope A. oth Holcomb, George W. oth St Peter, Shawn D. oth Enthalten in Academic Press Arteaga, Alberto A. ELSEVIER Iatrogenic pneumothorax during hypoglossal nerve stimulator implantation 2018 JSR : clinical and laboratory investigation : official publication of the Association for Academic Surgery : official publication of the Association of Veterans Administration Surgeons Orlando, Fla (DE-627)ELV00028954X volume:223 year:2018 pages:34-38 extent:5 https://doi.org/10.1016/j.jss.2017.06.082 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 44.94 Hals-Nasen-Ohrenheilkunde VZ AR 223 2018 34-38 5 045F 610 |
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Maturation of effect size during enrollment of prospective randomized trials |
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Randomized clinical trials are powered by calculating the minimum sample size required to achieve statistical significance, given an estimated effect size (ES). The ES is the raw difference between two treatment arms. ES quantifies the actual magnitude of clinical differences between cohorts and is usually reflective of the true meaning of the trial, regardless of statistical significance. Under a fixed protocol, we hypothesize that the ES may be attained at a smaller sample than predesigned. To investigate patterns of ES during enrollment, we analyzed completed trials that were completed at our institution. |
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Randomized clinical trials are powered by calculating the minimum sample size required to achieve statistical significance, given an estimated effect size (ES). The ES is the raw difference between two treatment arms. ES quantifies the actual magnitude of clinical differences between cohorts and is usually reflective of the true meaning of the trial, regardless of statistical significance. Under a fixed protocol, we hypothesize that the ES may be attained at a smaller sample than predesigned. To investigate patterns of ES during enrollment, we analyzed completed trials that were completed at our institution. |
| abstract_unstemmed |
Randomized clinical trials are powered by calculating the minimum sample size required to achieve statistical significance, given an estimated effect size (ES). The ES is the raw difference between two treatment arms. ES quantifies the actual magnitude of clinical differences between cohorts and is usually reflective of the true meaning of the trial, regardless of statistical significance. Under a fixed protocol, we hypothesize that the ES may be attained at a smaller sample than predesigned. To investigate patterns of ES during enrollment, we analyzed completed trials that were completed at our institution. |
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Maturation of effect size during enrollment of prospective randomized trials |
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https://doi.org/10.1016/j.jss.2017.06.082 |
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| author2 |
Oyetunji, Tolulope A. Holcomb, George W. St Peter, Shawn D. |
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10.1016/j.jss.2017.06.082 |
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2024-07-06T21:21:14.242Z |
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