Advantages of the Alpha-lipoic Acid Association with Chlorpromazine in a Model of Schizophrenia Induced by Ketamine in Rats: Behavioral and Oxidative Stress evidences
• KET induced hyperlocomotion, impaired working memory and decreased prepulse inhibition associated to oxidative stress. • Pre-treatment with CP, alone or associated to ALA, reverse effects of ketamine-induced schizophrenia. • Alpha-lipoic acid potentiates the antioxidant effect of chlorpromazine in...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Sampaio, Luis Rafael Leite [verfasserIn] Cysne Filho, Francisco Maurício Sales Patrocínio, Cláudio Felipe Vasconcelos |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2018 |
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| Schlagwörter: |
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| Umfang: |
10 |
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| Übergeordnetes Werk: |
Enthalten in: Status of beetroot processing and processed products: Thermal and emerging technologies intervention - Dhiman, Atul ELSEVIER, 2021, an international journal under the editorial direction of IBRO, Amsterdam [u.a.] |
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| Übergeordnetes Werk: |
volume:373 ; year:2018 ; day:1 ; month:03 ; pages:72-81 ; extent:10 |
| Links: |
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| DOI / URN: |
10.1016/j.neuroscience.2018.01.008 |
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Advantages of the Alpha-lipoic Acid Association with Chlorpromazine in a Model of Schizophrenia Induced by Ketamine in Rats: Behavioral and Oxidative Stress evidences |
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Advantages of the Alpha-lipoic Acid Association with Chlorpromazine in a Model of Schizophrenia Induced by Ketamine in Rats: Behavioral and Oxidative Stress evidences |
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Sampaio, Luis Rafael Leite |
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Status of beetroot processing and processed products: Thermal and emerging technologies intervention |
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Sampaio, Luis Rafael Leite |
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advantages of the alpha-lipoic acid association with chlorpromazine in a model of schizophrenia induced by ketamine in rats: behavioral and oxidative stress evidences |
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Advantages of the Alpha-lipoic Acid Association with Chlorpromazine in a Model of Schizophrenia Induced by Ketamine in Rats: Behavioral and Oxidative Stress evidences |
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• KET induced hyperlocomotion, impaired working memory and decreased prepulse inhibition associated to oxidative stress. • Pre-treatment with CP, alone or associated to ALA, reverse effects of ketamine-induced schizophrenia. • Alpha-lipoic acid potentiates the antioxidant effect of chlorpromazine in the hippocampus of rats. • Alpha-lipoic and chlorpromazine as a perspective of augmentation therapy in treatment of schizophrenia. |
| abstractGer |
• KET induced hyperlocomotion, impaired working memory and decreased prepulse inhibition associated to oxidative stress. • Pre-treatment with CP, alone or associated to ALA, reverse effects of ketamine-induced schizophrenia. • Alpha-lipoic acid potentiates the antioxidant effect of chlorpromazine in the hippocampus of rats. • Alpha-lipoic and chlorpromazine as a perspective of augmentation therapy in treatment of schizophrenia. |
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• KET induced hyperlocomotion, impaired working memory and decreased prepulse inhibition associated to oxidative stress. • Pre-treatment with CP, alone or associated to ALA, reverse effects of ketamine-induced schizophrenia. • Alpha-lipoic acid potentiates the antioxidant effect of chlorpromazine in the hippocampus of rats. • Alpha-lipoic and chlorpromazine as a perspective of augmentation therapy in treatment of schizophrenia. |
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Advantages of the Alpha-lipoic Acid Association with Chlorpromazine in a Model of Schizophrenia Induced by Ketamine in Rats: Behavioral and Oxidative Stress evidences |
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