Hydroxylated and sulfated metabolites of commonly occurring airborne polychlorinated biphenyls inhibit human steroid sulfotransferases SULT1E1 and SULT2A1
• Hydroxylated metabolites of airborne PCBs inhibited steroid sulfotransferases. • SULT1E1 and SULT2A1 differed in their specificities for OH-PCBs as inhibitors. • The corresponding PCB sulfates were either not inhibitory or were weak inhibitors. • Metabolites of these PCBs have the potential to aff...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Parker, Victoria S. [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2018 |
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| Schlagwörter: |
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| Umfang: |
6 |
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| Übergeordnetes Werk: |
Enthalten in: Evaluation of the proposed reporting system of the European LeukemiaNet and recommendations for prognosis of acute myeloid leukemia - 2013transfer abstract, Amsterdam [u.a.] |
|---|---|
| Übergeordnetes Werk: |
volume:58 ; year:2018 ; pages:196-201 ; extent:6 |
| Links: |
|---|
| DOI / URN: |
10.1016/j.etap.2018.01.010 |
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| Katalog-ID: |
ELV042054958 |
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| 245 | 1 | 0 | |a Hydroxylated and sulfated metabolites of commonly occurring airborne polychlorinated biphenyls inhibit human steroid sulfotransferases SULT1E1 and SULT2A1 |
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| 520 | |a • Hydroxylated metabolites of airborne PCBs inhibited steroid sulfotransferases. • SULT1E1 and SULT2A1 differed in their specificities for OH-PCBs as inhibitors. • The corresponding PCB sulfates were either not inhibitory or were weak inhibitors. • Metabolites of these PCBs have the potential to affect steroid hormone signaling. | ||
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| 700 | 1 | |a Duffel, Michael W. |4 oth | |
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10.1016/j.etap.2018.01.010 doi GBV00000000000143A.pica (DE-627)ELV042054958 (ELSEVIER)S1382-6689(18)30017-6 DE-627 ger DE-627 rakwb eng 610 610 DE-600 610 VZ 333.7 610 VZ 43.12 bkl 43.13 bkl 44.13 bkl Parker, Victoria S. verfasserin aut Hydroxylated and sulfated metabolites of commonly occurring airborne polychlorinated biphenyls inhibit human steroid sulfotransferases SULT1E1 and SULT2A1 2018 6 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier • Hydroxylated metabolites of airborne PCBs inhibited steroid sulfotransferases. • SULT1E1 and SULT2A1 differed in their specificities for OH-PCBs as inhibitors. • The corresponding PCB sulfates were either not inhibitory or were weak inhibitors. • Metabolites of these PCBs have the potential to affect steroid hormone signaling. DHEA Elsevier OH-PCB Elsevier 4-PCB 52 sulfate Elsevier 4′-OH PCB 25 Elsevier PCB 28 Elsevier 4-OH-PCB 8 Elsevier SULT Elsevier PCB Elsevier PAPS Elsevier 4-PCB 8 sulfate Elsevier 4-PCB 11 sulfate Elsevier DHEAS Elsevier SULT1E1 Elsevier 4-OH PCB 52 Elsevier 4-OH-PCB 11 Elsevier 4′-PCB 3 sulfate Elsevier 4′-OH PCB 3 Elsevier 4′-PCB 25 sulfate Elsevier SULT2A1 Elsevier Squirewell, Edwin J. oth Lehmler, Hans-Joachim oth Robertson, Larry W. oth Duffel, Michael W. oth Enthalten in Elsevier Evaluation of the proposed reporting system of the European LeukemiaNet and recommendations for prognosis of acute myeloid leukemia 2013transfer abstract Amsterdam [u.a.] (DE-627)ELV016627318 volume:58 year:2018 pages:196-201 extent:6 https://doi.org/10.1016/j.etap.2018.01.010 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA SSG-OPC-GGO GBV_ILN_40 GBV_ILN_70 GBV_ILN_131 43.12 Umweltchemie VZ 43.13 Umwelttoxikologie VZ 44.13 Medizinische Ökologie VZ AR 58 2018 196-201 6 045F 610 |
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10.1016/j.etap.2018.01.010 doi GBV00000000000143A.pica (DE-627)ELV042054958 (ELSEVIER)S1382-6689(18)30017-6 DE-627 ger DE-627 rakwb eng 610 610 DE-600 610 VZ 333.7 610 VZ 43.12 bkl 43.13 bkl 44.13 bkl Parker, Victoria S. verfasserin aut Hydroxylated and sulfated metabolites of commonly occurring airborne polychlorinated biphenyls inhibit human steroid sulfotransferases SULT1E1 and SULT2A1 2018 6 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier • Hydroxylated metabolites of airborne PCBs inhibited steroid sulfotransferases. • SULT1E1 and SULT2A1 differed in their specificities for OH-PCBs as inhibitors. • The corresponding PCB sulfates were either not inhibitory or were weak inhibitors. • Metabolites of these PCBs have the potential to affect steroid hormone signaling. DHEA Elsevier OH-PCB Elsevier 4-PCB 52 sulfate Elsevier 4′-OH PCB 25 Elsevier PCB 28 Elsevier 4-OH-PCB 8 Elsevier SULT Elsevier PCB Elsevier PAPS Elsevier 4-PCB 8 sulfate Elsevier 4-PCB 11 sulfate Elsevier DHEAS Elsevier SULT1E1 Elsevier 4-OH PCB 52 Elsevier 4-OH-PCB 11 Elsevier 4′-PCB 3 sulfate Elsevier 4′-OH PCB 3 Elsevier 4′-PCB 25 sulfate Elsevier SULT2A1 Elsevier Squirewell, Edwin J. oth Lehmler, Hans-Joachim oth Robertson, Larry W. oth Duffel, Michael W. oth Enthalten in Elsevier Evaluation of the proposed reporting system of the European LeukemiaNet and recommendations for prognosis of acute myeloid leukemia 2013transfer abstract Amsterdam [u.a.] (DE-627)ELV016627318 volume:58 year:2018 pages:196-201 extent:6 https://doi.org/10.1016/j.etap.2018.01.010 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA SSG-OPC-GGO GBV_ILN_40 GBV_ILN_70 GBV_ILN_131 43.12 Umweltchemie VZ 43.13 Umwelttoxikologie VZ 44.13 Medizinische Ökologie VZ AR 58 2018 196-201 6 045F 610 |
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10.1016/j.etap.2018.01.010 doi GBV00000000000143A.pica (DE-627)ELV042054958 (ELSEVIER)S1382-6689(18)30017-6 DE-627 ger DE-627 rakwb eng 610 610 DE-600 610 VZ 333.7 610 VZ 43.12 bkl 43.13 bkl 44.13 bkl Parker, Victoria S. verfasserin aut Hydroxylated and sulfated metabolites of commonly occurring airborne polychlorinated biphenyls inhibit human steroid sulfotransferases SULT1E1 and SULT2A1 2018 6 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier • Hydroxylated metabolites of airborne PCBs inhibited steroid sulfotransferases. • SULT1E1 and SULT2A1 differed in their specificities for OH-PCBs as inhibitors. • The corresponding PCB sulfates were either not inhibitory or were weak inhibitors. • Metabolites of these PCBs have the potential to affect steroid hormone signaling. DHEA Elsevier OH-PCB Elsevier 4-PCB 52 sulfate Elsevier 4′-OH PCB 25 Elsevier PCB 28 Elsevier 4-OH-PCB 8 Elsevier SULT Elsevier PCB Elsevier PAPS Elsevier 4-PCB 8 sulfate Elsevier 4-PCB 11 sulfate Elsevier DHEAS Elsevier SULT1E1 Elsevier 4-OH PCB 52 Elsevier 4-OH-PCB 11 Elsevier 4′-PCB 3 sulfate Elsevier 4′-OH PCB 3 Elsevier 4′-PCB 25 sulfate Elsevier SULT2A1 Elsevier Squirewell, Edwin J. oth Lehmler, Hans-Joachim oth Robertson, Larry W. oth Duffel, Michael W. oth Enthalten in Elsevier Evaluation of the proposed reporting system of the European LeukemiaNet and recommendations for prognosis of acute myeloid leukemia 2013transfer abstract Amsterdam [u.a.] (DE-627)ELV016627318 volume:58 year:2018 pages:196-201 extent:6 https://doi.org/10.1016/j.etap.2018.01.010 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA SSG-OPC-GGO GBV_ILN_40 GBV_ILN_70 GBV_ILN_131 43.12 Umweltchemie VZ 43.13 Umwelttoxikologie VZ 44.13 Medizinische Ökologie VZ AR 58 2018 196-201 6 045F 610 |
| allfieldsGer |
10.1016/j.etap.2018.01.010 doi GBV00000000000143A.pica (DE-627)ELV042054958 (ELSEVIER)S1382-6689(18)30017-6 DE-627 ger DE-627 rakwb eng 610 610 DE-600 610 VZ 333.7 610 VZ 43.12 bkl 43.13 bkl 44.13 bkl Parker, Victoria S. verfasserin aut Hydroxylated and sulfated metabolites of commonly occurring airborne polychlorinated biphenyls inhibit human steroid sulfotransferases SULT1E1 and SULT2A1 2018 6 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier • Hydroxylated metabolites of airborne PCBs inhibited steroid sulfotransferases. • SULT1E1 and SULT2A1 differed in their specificities for OH-PCBs as inhibitors. • The corresponding PCB sulfates were either not inhibitory or were weak inhibitors. • Metabolites of these PCBs have the potential to affect steroid hormone signaling. DHEA Elsevier OH-PCB Elsevier 4-PCB 52 sulfate Elsevier 4′-OH PCB 25 Elsevier PCB 28 Elsevier 4-OH-PCB 8 Elsevier SULT Elsevier PCB Elsevier PAPS Elsevier 4-PCB 8 sulfate Elsevier 4-PCB 11 sulfate Elsevier DHEAS Elsevier SULT1E1 Elsevier 4-OH PCB 52 Elsevier 4-OH-PCB 11 Elsevier 4′-PCB 3 sulfate Elsevier 4′-OH PCB 3 Elsevier 4′-PCB 25 sulfate Elsevier SULT2A1 Elsevier Squirewell, Edwin J. oth Lehmler, Hans-Joachim oth Robertson, Larry W. oth Duffel, Michael W. oth Enthalten in Elsevier Evaluation of the proposed reporting system of the European LeukemiaNet and recommendations for prognosis of acute myeloid leukemia 2013transfer abstract Amsterdam [u.a.] (DE-627)ELV016627318 volume:58 year:2018 pages:196-201 extent:6 https://doi.org/10.1016/j.etap.2018.01.010 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA SSG-OPC-GGO GBV_ILN_40 GBV_ILN_70 GBV_ILN_131 43.12 Umweltchemie VZ 43.13 Umwelttoxikologie VZ 44.13 Medizinische Ökologie VZ AR 58 2018 196-201 6 045F 610 |
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10.1016/j.etap.2018.01.010 doi GBV00000000000143A.pica (DE-627)ELV042054958 (ELSEVIER)S1382-6689(18)30017-6 DE-627 ger DE-627 rakwb eng 610 610 DE-600 610 VZ 333.7 610 VZ 43.12 bkl 43.13 bkl 44.13 bkl Parker, Victoria S. verfasserin aut Hydroxylated and sulfated metabolites of commonly occurring airborne polychlorinated biphenyls inhibit human steroid sulfotransferases SULT1E1 and SULT2A1 2018 6 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier • Hydroxylated metabolites of airborne PCBs inhibited steroid sulfotransferases. • SULT1E1 and SULT2A1 differed in their specificities for OH-PCBs as inhibitors. • The corresponding PCB sulfates were either not inhibitory or were weak inhibitors. • Metabolites of these PCBs have the potential to affect steroid hormone signaling. DHEA Elsevier OH-PCB Elsevier 4-PCB 52 sulfate Elsevier 4′-OH PCB 25 Elsevier PCB 28 Elsevier 4-OH-PCB 8 Elsevier SULT Elsevier PCB Elsevier PAPS Elsevier 4-PCB 8 sulfate Elsevier 4-PCB 11 sulfate Elsevier DHEAS Elsevier SULT1E1 Elsevier 4-OH PCB 52 Elsevier 4-OH-PCB 11 Elsevier 4′-PCB 3 sulfate Elsevier 4′-OH PCB 3 Elsevier 4′-PCB 25 sulfate Elsevier SULT2A1 Elsevier Squirewell, Edwin J. oth Lehmler, Hans-Joachim oth Robertson, Larry W. oth Duffel, Michael W. oth Enthalten in Elsevier Evaluation of the proposed reporting system of the European LeukemiaNet and recommendations for prognosis of acute myeloid leukemia 2013transfer abstract Amsterdam [u.a.] (DE-627)ELV016627318 volume:58 year:2018 pages:196-201 extent:6 https://doi.org/10.1016/j.etap.2018.01.010 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA SSG-OPC-GGO GBV_ILN_40 GBV_ILN_70 GBV_ILN_131 43.12 Umweltchemie VZ 43.13 Umwelttoxikologie VZ 44.13 Medizinische Ökologie VZ AR 58 2018 196-201 6 045F 610 |
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Enthalten in Evaluation of the proposed reporting system of the European LeukemiaNet and recommendations for prognosis of acute myeloid leukemia Amsterdam [u.a.] volume:58 year:2018 pages:196-201 extent:6 |
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DHEA OH-PCB 4-PCB 52 sulfate 4′-OH PCB 25 PCB 28 4-OH-PCB 8 SULT PCB PAPS 4-PCB 8 sulfate 4-PCB 11 sulfate DHEAS SULT1E1 4-OH PCB 52 4-OH-PCB 11 4′-PCB 3 sulfate 4′-OH PCB 3 4′-PCB 25 sulfate SULT2A1 |
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Evaluation of the proposed reporting system of the European LeukemiaNet and recommendations for prognosis of acute myeloid leukemia |
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Parker, Victoria S. @@aut@@ Squirewell, Edwin J. @@oth@@ Lehmler, Hans-Joachim @@oth@@ Robertson, Larry W. @@oth@@ Duffel, Michael W. @@oth@@ |
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Evaluation of the proposed reporting system of the European LeukemiaNet and recommendations for prognosis of acute myeloid leukemia |
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hydroxylated and sulfated metabolites of commonly occurring airborne polychlorinated biphenyls inhibit human steroid sulfotransferases sult1e1 and sult2a1 |
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Hydroxylated and sulfated metabolites of commonly occurring airborne polychlorinated biphenyls inhibit human steroid sulfotransferases SULT1E1 and SULT2A1 |
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• Hydroxylated metabolites of airborne PCBs inhibited steroid sulfotransferases. • SULT1E1 and SULT2A1 differed in their specificities for OH-PCBs as inhibitors. • The corresponding PCB sulfates were either not inhibitory or were weak inhibitors. • Metabolites of these PCBs have the potential to affect steroid hormone signaling. |
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• Hydroxylated metabolites of airborne PCBs inhibited steroid sulfotransferases. • SULT1E1 and SULT2A1 differed in their specificities for OH-PCBs as inhibitors. • The corresponding PCB sulfates were either not inhibitory or were weak inhibitors. • Metabolites of these PCBs have the potential to affect steroid hormone signaling. |
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• Hydroxylated metabolites of airborne PCBs inhibited steroid sulfotransferases. • SULT1E1 and SULT2A1 differed in their specificities for OH-PCBs as inhibitors. • The corresponding PCB sulfates were either not inhibitory or were weak inhibitors. • Metabolites of these PCBs have the potential to affect steroid hormone signaling. |
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Hydroxylated and sulfated metabolites of commonly occurring airborne polychlorinated biphenyls inhibit human steroid sulfotransferases SULT1E1 and SULT2A1 |
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