Loss of DEK induces radioresistance of murine restricted hematopoietic progenitors
• DEK loss causes restricted hematopoietic progenitor cells (HPCs) to enter quiescence (G0) in response to radiation. • DEK's role in radiation response is functionally unique in HPC-1 progenitors versus HPC-2 progenitors. • DEK loss causes aberrant radioresistance during early myeloid reconsti...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Serrano-Lopez, Juana [verfasserIn] |
|---|
| Format: |
E-Artikel |
|---|---|
| Sprache: |
Englisch |
| Erschienen: |
2018 |
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| Umfang: |
464 |
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| Übergeordnetes Werk: |
Enthalten in: Interfacing 2D M - Rawat, Ashima ELSEVIER, 2021, official publication of the International Society for Experimental Hematology, Amsterdam [u.a] |
|---|---|
| Übergeordnetes Werk: |
volume:59 ; year:2018 ; pages:40-503 ; extent:464 |
| Links: |
|---|
| DOI / URN: |
10.1016/j.exphem.2017.12.009 |
|---|
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ELV042165741 |
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| 245 | 1 | 0 | |a Loss of DEK induces radioresistance of murine restricted hematopoietic progenitors |
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| 520 | |a • DEK loss causes restricted hematopoietic progenitor cells (HPCs) to enter quiescence (G0) in response to radiation. • DEK's role in radiation response is functionally unique in HPC-1 progenitors versus HPC-2 progenitors. • DEK loss causes aberrant radioresistance during early myeloid reconstitution. | ||
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| 700 | 1 | |a Pease, Nicholas A. |4 oth | |
| 700 | 1 | |a Shephard, Miranda S. |4 oth | |
| 700 | 1 | |a Wellendorf, Ashley M. |4 oth | |
| 700 | 1 | |a Sertorio, Mathieu |4 oth | |
| 700 | 1 | |a Smith, Eric A. |4 oth | |
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| 700 | 1 | |a Wells, Susanne I. |4 oth | |
| 700 | 1 | |a Cancelas, Jose A. |4 oth | |
| 700 | 1 | |a Privette Vinnedge, Lisa M. |4 oth | |
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loss of dek induces radioresistance of murine restricted hematopoietic progenitors |
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Loss of DEK induces radioresistance of murine restricted hematopoietic progenitors |
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• DEK loss causes restricted hematopoietic progenitor cells (HPCs) to enter quiescence (G0) in response to radiation. • DEK's role in radiation response is functionally unique in HPC-1 progenitors versus HPC-2 progenitors. • DEK loss causes aberrant radioresistance during early myeloid reconstitution. |
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• DEK loss causes restricted hematopoietic progenitor cells (HPCs) to enter quiescence (G0) in response to radiation. • DEK's role in radiation response is functionally unique in HPC-1 progenitors versus HPC-2 progenitors. • DEK loss causes aberrant radioresistance during early myeloid reconstitution. |
| abstract_unstemmed |
• DEK loss causes restricted hematopoietic progenitor cells (HPCs) to enter quiescence (G0) in response to radiation. • DEK's role in radiation response is functionally unique in HPC-1 progenitors versus HPC-2 progenitors. • DEK loss causes aberrant radioresistance during early myeloid reconstitution. |
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Loss of DEK induces radioresistance of murine restricted hematopoietic progenitors |
| url |
https://doi.org/10.1016/j.exphem.2017.12.009 |
| remote_bool |
true |
| author2 |
Nattamai, Kalpana Pease, Nicholas A. Shephard, Miranda S. Wellendorf, Ashley M. Sertorio, Mathieu Smith, Eric A. Geiger, Hartmut Wells, Susanne I. Cancelas, Jose A. Privette Vinnedge, Lisa M. |
| author2Str |
Nattamai, Kalpana Pease, Nicholas A. Shephard, Miranda S. Wellendorf, Ashley M. Sertorio, Mathieu Smith, Eric A. Geiger, Hartmut Wells, Susanne I. Cancelas, Jose A. Privette Vinnedge, Lisa M. |
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ELV006315852 |
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oth oth oth oth oth oth oth oth oth oth |
| doi_str |
10.1016/j.exphem.2017.12.009 |
| up_date |
2024-07-06T22:05:07.461Z |
| _version_ |
1803868970640474112 |
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