Diagnosis of recurrent venous thromboembolism
The diagnostic management of suspected recurrent venous thromboembolism (VTE) is challenging for four main reasons. First, clinical decision rules are less useful to identity patients with a low pre-test probability. Second, the diagnostic performance of D-dimer tests is decreased. Together, these t...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Barco, Stefano [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2018transfer abstract |
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| Umfang: |
7 |
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| Übergeordnetes Werk: |
Enthalten in: DNA-PKcs Expression Predicts Response to Radiotherapy in Prostate Cancer - 2012, vascular obstruction, hemorrhage and hemostasis, Amsterdam [u.a.] |
|---|---|
| Übergeordnetes Werk: |
volume:163 ; year:2018 ; pages:229-235 ; extent:7 |
| Links: |
|---|
| DOI / URN: |
10.1016/j.thromres.2017.05.026 |
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| 520 | |a The diagnostic management of suspected recurrent venous thromboembolism (VTE) is challenging for four main reasons. First, clinical decision rules are less useful to identity patients with a low pre-test probability. Second, the diagnostic performance of D-dimer tests is decreased. Together, these two point lead to a clearly lower proportion of patients in whom recurrent VTE can be ruled out without performing imaging tests. Third, recurrent thrombi may be difficult to differentiate from residual thrombi, which may be often identified in patients with a history of VTE. Fourth and lastly, the prevalence of VTE in patients with suspected recurrent disease is higher than in patients with suspected first VTE. As a consequence, the failure rates of the algorithms in patients with suspected recurrent VTE are higher as well, underling the relevance of accurate diagnostic management of this specific patient population. There is a lack of large well designed diagnostic studies that focus mainly on patients with prior VTE. Even so, available evidence suggests that diagnostic algorithms validated for first VTE are also largely applicable to suspected recurrent VTE. Emerging imaging techniques such as magnetic resonance direct thrombus imaging (MRDTI) are likely to improve the accuracy of the algorithms in the near future. | ||
| 520 | |a The diagnostic management of suspected recurrent venous thromboembolism (VTE) is challenging for four main reasons. First, clinical decision rules are less useful to identity patients with a low pre-test probability. Second, the diagnostic performance of D-dimer tests is decreased. Together, these two point lead to a clearly lower proportion of patients in whom recurrent VTE can be ruled out without performing imaging tests. Third, recurrent thrombi may be difficult to differentiate from residual thrombi, which may be often identified in patients with a history of VTE. Fourth and lastly, the prevalence of VTE in patients with suspected recurrent disease is higher than in patients with suspected first VTE. As a consequence, the failure rates of the algorithms in patients with suspected recurrent VTE are higher as well, underling the relevance of accurate diagnostic management of this specific patient population. There is a lack of large well designed diagnostic studies that focus mainly on patients with prior VTE. Even so, available evidence suggests that diagnostic algorithms validated for first VTE are also largely applicable to suspected recurrent VTE. Emerging imaging techniques such as magnetic resonance direct thrombus imaging (MRDTI) are likely to improve the accuracy of the algorithms in the near future. | ||
| 700 | 1 | |a Konstantinides, Stavros |4 oth | |
| 700 | 1 | |a Huisman, Menno V. |4 oth | |
| 700 | 1 | |a Klok, Frederikus A. |4 oth | |
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10.1016/j.thromres.2017.05.026 doi GBV00000000000315_01.pica (DE-627)ELV042513286 (ELSEVIER)S0049-3848(17)30344-4 DE-627 ger DE-627 rakwb eng 610 VZ 610 VZ 44.40 bkl Barco, Stefano verfasserin aut Diagnosis of recurrent venous thromboembolism 2018transfer abstract 7 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier The diagnostic management of suspected recurrent venous thromboembolism (VTE) is challenging for four main reasons. First, clinical decision rules are less useful to identity patients with a low pre-test probability. Second, the diagnostic performance of D-dimer tests is decreased. Together, these two point lead to a clearly lower proportion of patients in whom recurrent VTE can be ruled out without performing imaging tests. Third, recurrent thrombi may be difficult to differentiate from residual thrombi, which may be often identified in patients with a history of VTE. Fourth and lastly, the prevalence of VTE in patients with suspected recurrent disease is higher than in patients with suspected first VTE. As a consequence, the failure rates of the algorithms in patients with suspected recurrent VTE are higher as well, underling the relevance of accurate diagnostic management of this specific patient population. There is a lack of large well designed diagnostic studies that focus mainly on patients with prior VTE. Even so, available evidence suggests that diagnostic algorithms validated for first VTE are also largely applicable to suspected recurrent VTE. Emerging imaging techniques such as magnetic resonance direct thrombus imaging (MRDTI) are likely to improve the accuracy of the algorithms in the near future. The diagnostic management of suspected recurrent venous thromboembolism (VTE) is challenging for four main reasons. First, clinical decision rules are less useful to identity patients with a low pre-test probability. Second, the diagnostic performance of D-dimer tests is decreased. Together, these two point lead to a clearly lower proportion of patients in whom recurrent VTE can be ruled out without performing imaging tests. Third, recurrent thrombi may be difficult to differentiate from residual thrombi, which may be often identified in patients with a history of VTE. Fourth and lastly, the prevalence of VTE in patients with suspected recurrent disease is higher than in patients with suspected first VTE. As a consequence, the failure rates of the algorithms in patients with suspected recurrent VTE are higher as well, underling the relevance of accurate diagnostic management of this specific patient population. There is a lack of large well designed diagnostic studies that focus mainly on patients with prior VTE. Even so, available evidence suggests that diagnostic algorithms validated for first VTE are also largely applicable to suspected recurrent VTE. Emerging imaging techniques such as magnetic resonance direct thrombus imaging (MRDTI) are likely to improve the accuracy of the algorithms in the near future. Konstantinides, Stavros oth Huisman, Menno V. oth Klok, Frederikus A. oth Enthalten in Elsevier Science DNA-PKcs Expression Predicts Response to Radiotherapy in Prostate Cancer 2012 vascular obstruction, hemorrhage and hemostasis Amsterdam [u.a.] (DE-627)ELV011105356 volume:163 year:2018 pages:229-235 extent:7 https://doi.org/10.1016/j.thromres.2017.05.026 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA SSG-OPC-PHA GBV_ILN_24 GBV_ILN_40 44.40 Pharmazie Pharmazeutika VZ AR 163 2018 229-235 7 |
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10.1016/j.thromres.2017.05.026 doi GBV00000000000315_01.pica (DE-627)ELV042513286 (ELSEVIER)S0049-3848(17)30344-4 DE-627 ger DE-627 rakwb eng 610 VZ 610 VZ 44.40 bkl Barco, Stefano verfasserin aut Diagnosis of recurrent venous thromboembolism 2018transfer abstract 7 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier The diagnostic management of suspected recurrent venous thromboembolism (VTE) is challenging for four main reasons. First, clinical decision rules are less useful to identity patients with a low pre-test probability. Second, the diagnostic performance of D-dimer tests is decreased. Together, these two point lead to a clearly lower proportion of patients in whom recurrent VTE can be ruled out without performing imaging tests. Third, recurrent thrombi may be difficult to differentiate from residual thrombi, which may be often identified in patients with a history of VTE. Fourth and lastly, the prevalence of VTE in patients with suspected recurrent disease is higher than in patients with suspected first VTE. As a consequence, the failure rates of the algorithms in patients with suspected recurrent VTE are higher as well, underling the relevance of accurate diagnostic management of this specific patient population. There is a lack of large well designed diagnostic studies that focus mainly on patients with prior VTE. Even so, available evidence suggests that diagnostic algorithms validated for first VTE are also largely applicable to suspected recurrent VTE. Emerging imaging techniques such as magnetic resonance direct thrombus imaging (MRDTI) are likely to improve the accuracy of the algorithms in the near future. The diagnostic management of suspected recurrent venous thromboembolism (VTE) is challenging for four main reasons. First, clinical decision rules are less useful to identity patients with a low pre-test probability. Second, the diagnostic performance of D-dimer tests is decreased. Together, these two point lead to a clearly lower proportion of patients in whom recurrent VTE can be ruled out without performing imaging tests. Third, recurrent thrombi may be difficult to differentiate from residual thrombi, which may be often identified in patients with a history of VTE. Fourth and lastly, the prevalence of VTE in patients with suspected recurrent disease is higher than in patients with suspected first VTE. As a consequence, the failure rates of the algorithms in patients with suspected recurrent VTE are higher as well, underling the relevance of accurate diagnostic management of this specific patient population. There is a lack of large well designed diagnostic studies that focus mainly on patients with prior VTE. Even so, available evidence suggests that diagnostic algorithms validated for first VTE are also largely applicable to suspected recurrent VTE. Emerging imaging techniques such as magnetic resonance direct thrombus imaging (MRDTI) are likely to improve the accuracy of the algorithms in the near future. Konstantinides, Stavros oth Huisman, Menno V. oth Klok, Frederikus A. oth Enthalten in Elsevier Science DNA-PKcs Expression Predicts Response to Radiotherapy in Prostate Cancer 2012 vascular obstruction, hemorrhage and hemostasis Amsterdam [u.a.] (DE-627)ELV011105356 volume:163 year:2018 pages:229-235 extent:7 https://doi.org/10.1016/j.thromres.2017.05.026 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA SSG-OPC-PHA GBV_ILN_24 GBV_ILN_40 44.40 Pharmazie Pharmazeutika VZ AR 163 2018 229-235 7 |
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10.1016/j.thromres.2017.05.026 doi GBV00000000000315_01.pica (DE-627)ELV042513286 (ELSEVIER)S0049-3848(17)30344-4 DE-627 ger DE-627 rakwb eng 610 VZ 610 VZ 44.40 bkl Barco, Stefano verfasserin aut Diagnosis of recurrent venous thromboembolism 2018transfer abstract 7 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier The diagnostic management of suspected recurrent venous thromboembolism (VTE) is challenging for four main reasons. First, clinical decision rules are less useful to identity patients with a low pre-test probability. Second, the diagnostic performance of D-dimer tests is decreased. Together, these two point lead to a clearly lower proportion of patients in whom recurrent VTE can be ruled out without performing imaging tests. Third, recurrent thrombi may be difficult to differentiate from residual thrombi, which may be often identified in patients with a history of VTE. Fourth and lastly, the prevalence of VTE in patients with suspected recurrent disease is higher than in patients with suspected first VTE. As a consequence, the failure rates of the algorithms in patients with suspected recurrent VTE are higher as well, underling the relevance of accurate diagnostic management of this specific patient population. There is a lack of large well designed diagnostic studies that focus mainly on patients with prior VTE. Even so, available evidence suggests that diagnostic algorithms validated for first VTE are also largely applicable to suspected recurrent VTE. Emerging imaging techniques such as magnetic resonance direct thrombus imaging (MRDTI) are likely to improve the accuracy of the algorithms in the near future. The diagnostic management of suspected recurrent venous thromboembolism (VTE) is challenging for four main reasons. First, clinical decision rules are less useful to identity patients with a low pre-test probability. Second, the diagnostic performance of D-dimer tests is decreased. Together, these two point lead to a clearly lower proportion of patients in whom recurrent VTE can be ruled out without performing imaging tests. Third, recurrent thrombi may be difficult to differentiate from residual thrombi, which may be often identified in patients with a history of VTE. Fourth and lastly, the prevalence of VTE in patients with suspected recurrent disease is higher than in patients with suspected first VTE. As a consequence, the failure rates of the algorithms in patients with suspected recurrent VTE are higher as well, underling the relevance of accurate diagnostic management of this specific patient population. There is a lack of large well designed diagnostic studies that focus mainly on patients with prior VTE. Even so, available evidence suggests that diagnostic algorithms validated for first VTE are also largely applicable to suspected recurrent VTE. Emerging imaging techniques such as magnetic resonance direct thrombus imaging (MRDTI) are likely to improve the accuracy of the algorithms in the near future. Konstantinides, Stavros oth Huisman, Menno V. oth Klok, Frederikus A. oth Enthalten in Elsevier Science DNA-PKcs Expression Predicts Response to Radiotherapy in Prostate Cancer 2012 vascular obstruction, hemorrhage and hemostasis Amsterdam [u.a.] (DE-627)ELV011105356 volume:163 year:2018 pages:229-235 extent:7 https://doi.org/10.1016/j.thromres.2017.05.026 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA SSG-OPC-PHA GBV_ILN_24 GBV_ILN_40 44.40 Pharmazie Pharmazeutika VZ AR 163 2018 229-235 7 |
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10.1016/j.thromres.2017.05.026 doi GBV00000000000315_01.pica (DE-627)ELV042513286 (ELSEVIER)S0049-3848(17)30344-4 DE-627 ger DE-627 rakwb eng 610 VZ 610 VZ 44.40 bkl Barco, Stefano verfasserin aut Diagnosis of recurrent venous thromboembolism 2018transfer abstract 7 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier The diagnostic management of suspected recurrent venous thromboembolism (VTE) is challenging for four main reasons. First, clinical decision rules are less useful to identity patients with a low pre-test probability. Second, the diagnostic performance of D-dimer tests is decreased. Together, these two point lead to a clearly lower proportion of patients in whom recurrent VTE can be ruled out without performing imaging tests. Third, recurrent thrombi may be difficult to differentiate from residual thrombi, which may be often identified in patients with a history of VTE. Fourth and lastly, the prevalence of VTE in patients with suspected recurrent disease is higher than in patients with suspected first VTE. As a consequence, the failure rates of the algorithms in patients with suspected recurrent VTE are higher as well, underling the relevance of accurate diagnostic management of this specific patient population. There is a lack of large well designed diagnostic studies that focus mainly on patients with prior VTE. Even so, available evidence suggests that diagnostic algorithms validated for first VTE are also largely applicable to suspected recurrent VTE. Emerging imaging techniques such as magnetic resonance direct thrombus imaging (MRDTI) are likely to improve the accuracy of the algorithms in the near future. The diagnostic management of suspected recurrent venous thromboembolism (VTE) is challenging for four main reasons. First, clinical decision rules are less useful to identity patients with a low pre-test probability. Second, the diagnostic performance of D-dimer tests is decreased. Together, these two point lead to a clearly lower proportion of patients in whom recurrent VTE can be ruled out without performing imaging tests. Third, recurrent thrombi may be difficult to differentiate from residual thrombi, which may be often identified in patients with a history of VTE. Fourth and lastly, the prevalence of VTE in patients with suspected recurrent disease is higher than in patients with suspected first VTE. As a consequence, the failure rates of the algorithms in patients with suspected recurrent VTE are higher as well, underling the relevance of accurate diagnostic management of this specific patient population. There is a lack of large well designed diagnostic studies that focus mainly on patients with prior VTE. Even so, available evidence suggests that diagnostic algorithms validated for first VTE are also largely applicable to suspected recurrent VTE. Emerging imaging techniques such as magnetic resonance direct thrombus imaging (MRDTI) are likely to improve the accuracy of the algorithms in the near future. Konstantinides, Stavros oth Huisman, Menno V. oth Klok, Frederikus A. oth Enthalten in Elsevier Science DNA-PKcs Expression Predicts Response to Radiotherapy in Prostate Cancer 2012 vascular obstruction, hemorrhage and hemostasis Amsterdam [u.a.] (DE-627)ELV011105356 volume:163 year:2018 pages:229-235 extent:7 https://doi.org/10.1016/j.thromres.2017.05.026 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA SSG-OPC-PHA GBV_ILN_24 GBV_ILN_40 44.40 Pharmazie Pharmazeutika VZ AR 163 2018 229-235 7 |
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10.1016/j.thromres.2017.05.026 doi GBV00000000000315_01.pica (DE-627)ELV042513286 (ELSEVIER)S0049-3848(17)30344-4 DE-627 ger DE-627 rakwb eng 610 VZ 610 VZ 44.40 bkl Barco, Stefano verfasserin aut Diagnosis of recurrent venous thromboembolism 2018transfer abstract 7 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier The diagnostic management of suspected recurrent venous thromboembolism (VTE) is challenging for four main reasons. First, clinical decision rules are less useful to identity patients with a low pre-test probability. Second, the diagnostic performance of D-dimer tests is decreased. Together, these two point lead to a clearly lower proportion of patients in whom recurrent VTE can be ruled out without performing imaging tests. Third, recurrent thrombi may be difficult to differentiate from residual thrombi, which may be often identified in patients with a history of VTE. Fourth and lastly, the prevalence of VTE in patients with suspected recurrent disease is higher than in patients with suspected first VTE. As a consequence, the failure rates of the algorithms in patients with suspected recurrent VTE are higher as well, underling the relevance of accurate diagnostic management of this specific patient population. There is a lack of large well designed diagnostic studies that focus mainly on patients with prior VTE. Even so, available evidence suggests that diagnostic algorithms validated for first VTE are also largely applicable to suspected recurrent VTE. Emerging imaging techniques such as magnetic resonance direct thrombus imaging (MRDTI) are likely to improve the accuracy of the algorithms in the near future. The diagnostic management of suspected recurrent venous thromboembolism (VTE) is challenging for four main reasons. First, clinical decision rules are less useful to identity patients with a low pre-test probability. Second, the diagnostic performance of D-dimer tests is decreased. Together, these two point lead to a clearly lower proportion of patients in whom recurrent VTE can be ruled out without performing imaging tests. Third, recurrent thrombi may be difficult to differentiate from residual thrombi, which may be often identified in patients with a history of VTE. Fourth and lastly, the prevalence of VTE in patients with suspected recurrent disease is higher than in patients with suspected first VTE. As a consequence, the failure rates of the algorithms in patients with suspected recurrent VTE are higher as well, underling the relevance of accurate diagnostic management of this specific patient population. There is a lack of large well designed diagnostic studies that focus mainly on patients with prior VTE. Even so, available evidence suggests that diagnostic algorithms validated for first VTE are also largely applicable to suspected recurrent VTE. Emerging imaging techniques such as magnetic resonance direct thrombus imaging (MRDTI) are likely to improve the accuracy of the algorithms in the near future. Konstantinides, Stavros oth Huisman, Menno V. oth Klok, Frederikus A. oth Enthalten in Elsevier Science DNA-PKcs Expression Predicts Response to Radiotherapy in Prostate Cancer 2012 vascular obstruction, hemorrhage and hemostasis Amsterdam [u.a.] (DE-627)ELV011105356 volume:163 year:2018 pages:229-235 extent:7 https://doi.org/10.1016/j.thromres.2017.05.026 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA SSG-OPC-PHA GBV_ILN_24 GBV_ILN_40 44.40 Pharmazie Pharmazeutika VZ AR 163 2018 229-235 7 |
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First, clinical decision rules are less useful to identity patients with a low pre-test probability. Second, the diagnostic performance of D-dimer tests is decreased. Together, these two point lead to a clearly lower proportion of patients in whom recurrent VTE can be ruled out without performing imaging tests. Third, recurrent thrombi may be difficult to differentiate from residual thrombi, which may be often identified in patients with a history of VTE. Fourth and lastly, the prevalence of VTE in patients with suspected recurrent disease is higher than in patients with suspected first VTE. As a consequence, the failure rates of the algorithms in patients with suspected recurrent VTE are higher as well, underling the relevance of accurate diagnostic management of this specific patient population. There is a lack of large well designed diagnostic studies that focus mainly on patients with prior VTE. 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The diagnostic management of suspected recurrent venous thromboembolism (VTE) is challenging for four main reasons. First, clinical decision rules are less useful to identity patients with a low pre-test probability. Second, the diagnostic performance of D-dimer tests is decreased. Together, these two point lead to a clearly lower proportion of patients in whom recurrent VTE can be ruled out without performing imaging tests. Third, recurrent thrombi may be difficult to differentiate from residual thrombi, which may be often identified in patients with a history of VTE. Fourth and lastly, the prevalence of VTE in patients with suspected recurrent disease is higher than in patients with suspected first VTE. As a consequence, the failure rates of the algorithms in patients with suspected recurrent VTE are higher as well, underling the relevance of accurate diagnostic management of this specific patient population. There is a lack of large well designed diagnostic studies that focus mainly on patients with prior VTE. Even so, available evidence suggests that diagnostic algorithms validated for first VTE are also largely applicable to suspected recurrent VTE. Emerging imaging techniques such as magnetic resonance direct thrombus imaging (MRDTI) are likely to improve the accuracy of the algorithms in the near future. |
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The diagnostic management of suspected recurrent venous thromboembolism (VTE) is challenging for four main reasons. First, clinical decision rules are less useful to identity patients with a low pre-test probability. Second, the diagnostic performance of D-dimer tests is decreased. Together, these two point lead to a clearly lower proportion of patients in whom recurrent VTE can be ruled out without performing imaging tests. Third, recurrent thrombi may be difficult to differentiate from residual thrombi, which may be often identified in patients with a history of VTE. Fourth and lastly, the prevalence of VTE in patients with suspected recurrent disease is higher than in patients with suspected first VTE. As a consequence, the failure rates of the algorithms in patients with suspected recurrent VTE are higher as well, underling the relevance of accurate diagnostic management of this specific patient population. There is a lack of large well designed diagnostic studies that focus mainly on patients with prior VTE. Even so, available evidence suggests that diagnostic algorithms validated for first VTE are also largely applicable to suspected recurrent VTE. Emerging imaging techniques such as magnetic resonance direct thrombus imaging (MRDTI) are likely to improve the accuracy of the algorithms in the near future. |
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The diagnostic management of suspected recurrent venous thromboembolism (VTE) is challenging for four main reasons. First, clinical decision rules are less useful to identity patients with a low pre-test probability. Second, the diagnostic performance of D-dimer tests is decreased. Together, these two point lead to a clearly lower proportion of patients in whom recurrent VTE can be ruled out without performing imaging tests. Third, recurrent thrombi may be difficult to differentiate from residual thrombi, which may be often identified in patients with a history of VTE. Fourth and lastly, the prevalence of VTE in patients with suspected recurrent disease is higher than in patients with suspected first VTE. As a consequence, the failure rates of the algorithms in patients with suspected recurrent VTE are higher as well, underling the relevance of accurate diagnostic management of this specific patient population. There is a lack of large well designed diagnostic studies that focus mainly on patients with prior VTE. Even so, available evidence suggests that diagnostic algorithms validated for first VTE are also largely applicable to suspected recurrent VTE. Emerging imaging techniques such as magnetic resonance direct thrombus imaging (MRDTI) are likely to improve the accuracy of the algorithms in the near future. |
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