Sarcomatoid renal cell carcinoma: Biology and treatment advances
Sarcomatoid transformation in renal cell carcinoma, so called sacromatoid RCC (sRCC), is associated with an aggressive behavior and a poor prognosis. Current therapeutic approaches are largely ineffective. Recent studies looking into the genomic and molecular characterization of sRCCs have provided...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Mouallem, Nemer El [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2018 |
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| Schlagwörter: |
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| Umfang: |
7 |
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| Übergeordnetes Werk: |
Enthalten in: BOLD matches neuronal activity at the mm scale: A combined 7T fMRI and ECoG study in human sensorimotor cortex - Siero, Jeroen C.W. ELSEVIER, 2014transfer abstract, Amsterdam [u.a.] |
|---|---|
| Übergeordnetes Werk: |
volume:36 ; year:2018 ; number:6 ; pages:265-271 ; extent:7 |
| Links: |
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| DOI / URN: |
10.1016/j.urolonc.2017.12.012 |
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| 520 | |a Sarcomatoid transformation in renal cell carcinoma, so called sacromatoid RCC (sRCC), is associated with an aggressive behavior and a poor prognosis. Current therapeutic approaches are largely ineffective. Recent studies looking into the genomic and molecular characterization of sRCCs have provided insights into the biology and pathogenesis of this entity. These advances in molecular signatures may help development of effective treatment strategies. We herein present a review of recent developments in the pathology, biology, and treatment modalities in sRCC. | ||
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10.1016/j.urolonc.2017.12.012 doi GBV00000000000234A.pica (DE-627)ELV043079229 (ELSEVIER)S1078-1439(17)30625-7 DE-627 ger DE-627 rakwb eng 610 610 DE-600 610 VZ Mouallem, Nemer El verfasserin aut Sarcomatoid renal cell carcinoma: Biology and treatment advances 2018 7 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Sarcomatoid transformation in renal cell carcinoma, so called sacromatoid RCC (sRCC), is associated with an aggressive behavior and a poor prognosis. Current therapeutic approaches are largely ineffective. Recent studies looking into the genomic and molecular characterization of sRCCs have provided insights into the biology and pathogenesis of this entity. These advances in molecular signatures may help development of effective treatment strategies. We herein present a review of recent developments in the pathology, biology, and treatment modalities in sRCC. Chemotherapy Elsevier Nephrectomy Elsevier Renal cell carcinoma Elsevier Targeted therapy Elsevier Immunotherapy Elsevier Sarcomatoid renal cell carcinoma Elsevier Smith, Steven C. oth Paul, Asit K. oth Enthalten in Elsevier Science Siero, Jeroen C.W. ELSEVIER BOLD matches neuronal activity at the mm scale: A combined 7T fMRI and ECoG study in human sensorimotor cortex 2014transfer abstract Amsterdam [u.a.] (DE-627)ELV012523860 volume:36 year:2018 number:6 pages:265-271 extent:7 https://doi.org/10.1016/j.urolonc.2017.12.012 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U AR 36 2018 6 265-271 7 045F 610 |
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Sarcomatoid transformation in renal cell carcinoma, so called sacromatoid RCC (sRCC), is associated with an aggressive behavior and a poor prognosis. Current therapeutic approaches are largely ineffective. Recent studies looking into the genomic and molecular characterization of sRCCs have provided insights into the biology and pathogenesis of this entity. These advances in molecular signatures may help development of effective treatment strategies. We herein present a review of recent developments in the pathology, biology, and treatment modalities in sRCC. |
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Sarcomatoid transformation in renal cell carcinoma, so called sacromatoid RCC (sRCC), is associated with an aggressive behavior and a poor prognosis. Current therapeutic approaches are largely ineffective. Recent studies looking into the genomic and molecular characterization of sRCCs have provided insights into the biology and pathogenesis of this entity. These advances in molecular signatures may help development of effective treatment strategies. We herein present a review of recent developments in the pathology, biology, and treatment modalities in sRCC. |
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Sarcomatoid transformation in renal cell carcinoma, so called sacromatoid RCC (sRCC), is associated with an aggressive behavior and a poor prognosis. Current therapeutic approaches are largely ineffective. Recent studies looking into the genomic and molecular characterization of sRCCs have provided insights into the biology and pathogenesis of this entity. These advances in molecular signatures may help development of effective treatment strategies. We herein present a review of recent developments in the pathology, biology, and treatment modalities in sRCC. |
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