Comparison of blood sampling methods for plasma corticosterone measurements in mice associated with minimal stress-related artefacts
• Collecting blood from mice causes artificial hypercorticosteronaemia due to stress. • Anaesthesia raises plasma corticosterone levels to up to twenty times above baseline. • Tail snip blood sampling causes minimal changes in corticosterone levels. • However, repeat tail snip collection causes sust...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Kim, Sarah [verfasserIn] |
|---|
| Format: |
E-Artikel |
|---|---|
| Sprache: |
Englisch |
| Erschienen: |
2018 |
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| Schlagwörter: |
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| Umfang: |
4 |
|---|
| Übergeordnetes Werk: |
Enthalten in: Childhood-only epilepsy with generalized tonic-clonic seizures: A well-defined epileptic syndrome - Caraballo, Roberto ELSEVIER, 2019, official publication of the International Study Group for Steroid Hormones, Amsterdam [u.a.] |
|---|---|
| Übergeordnetes Werk: |
volume:135 ; year:2018 ; pages:69-72 ; extent:4 |
| Links: |
|---|
| DOI / URN: |
10.1016/j.steroids.2018.03.004 |
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ELV043101232 |
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| 520 | |a • Collecting blood from mice causes artificial hypercorticosteronaemia due to stress. • Anaesthesia raises plasma corticosterone levels to up to twenty times above baseline. • Tail snip blood sampling causes minimal changes in corticosterone levels. • However, repeat tail snip collection causes sustained hypercorticosteronaemia. • Unrestrained tail snip sampling should be used for single time point analyses. | ||
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10.1016/j.steroids.2018.03.004 doi GBV00000000000235A.pica (DE-627)ELV043101232 (ELSEVIER)S0039-128X(18)30057-6 DE-627 ger DE-627 rakwb eng 610 540 610 DE-600 540 DE-600 610 VZ 44.90 bkl Kim, Sarah verfasserin aut Comparison of blood sampling methods for plasma corticosterone measurements in mice associated with minimal stress-related artefacts 2018 4 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier • Collecting blood from mice causes artificial hypercorticosteronaemia due to stress. • Anaesthesia raises plasma corticosterone levels to up to twenty times above baseline. • Tail snip blood sampling causes minimal changes in corticosterone levels. • However, repeat tail snip collection causes sustained hypercorticosteronaemia. • Unrestrained tail snip sampling should be used for single time point analyses. Corticosterone Elsevier Mice Elsevier Glucocorticoid measurement Elsevier Stress Elsevier Blood sampling Elsevier Foong, Daphne oth Cooper, Mark S. oth Seibel, Markus J. oth Zhou, Hong oth Enthalten in Elsevier Science Caraballo, Roberto ELSEVIER Childhood-only epilepsy with generalized tonic-clonic seizures: A well-defined epileptic syndrome 2019 official publication of the International Study Group for Steroid Hormones Amsterdam [u.a.] (DE-627)ELV002129892 volume:135 year:2018 pages:69-72 extent:4 https://doi.org/10.1016/j.steroids.2018.03.004 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 44.90 Neurologie VZ AR 135 2018 69-72 4 045F 610 |
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Comparison of blood sampling methods for plasma corticosterone measurements in mice associated with minimal stress-related artefacts |
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• Collecting blood from mice causes artificial hypercorticosteronaemia due to stress. • Anaesthesia raises plasma corticosterone levels to up to twenty times above baseline. • Tail snip blood sampling causes minimal changes in corticosterone levels. • However, repeat tail snip collection causes sustained hypercorticosteronaemia. • Unrestrained tail snip sampling should be used for single time point analyses. |
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• Collecting blood from mice causes artificial hypercorticosteronaemia due to stress. • Anaesthesia raises plasma corticosterone levels to up to twenty times above baseline. • Tail snip blood sampling causes minimal changes in corticosterone levels. • However, repeat tail snip collection causes sustained hypercorticosteronaemia. • Unrestrained tail snip sampling should be used for single time point analyses. |
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• Collecting blood from mice causes artificial hypercorticosteronaemia due to stress. • Anaesthesia raises plasma corticosterone levels to up to twenty times above baseline. • Tail snip blood sampling causes minimal changes in corticosterone levels. • However, repeat tail snip collection causes sustained hypercorticosteronaemia. • Unrestrained tail snip sampling should be used for single time point analyses. |
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