MEK inhibitor trametinib in combination with gemcitabine regresses a patient-derived orthotopic xenograft (PDOX) pancreatic cancer nude mouse model
• Combination of GEM and TRA seems to have great promise for pancreatic cancer. • Acute toxicity was not associated with the strong efficacy of GEM and TRA. • High level of tumor necrosis and fibrosis was observed in the combination therapy.
Gespeichert in:
| Autor*in: |
Kawaguchi, Kei [verfasserIn] |
|---|
| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2018 |
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| Schlagwörter: |
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5 |
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| Übergeordnetes Werk: |
Enthalten in: A novel Hemi-Body Irradiation technique using electron beams (HBIe - Delinikolas, Panagiotis ELSEVIER, 2017, New York, NY |
|---|---|
| Übergeordnetes Werk: |
volume:52 ; year:2018 ; pages:124-128 ; extent:5 |
| Links: |
|---|
| DOI / URN: |
10.1016/j.tice.2018.05.003 |
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A novel Hemi-Body Irradiation technique using electron beams (HBIe |
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A novel Hemi-Body Irradiation technique using electron beams (HBIe |
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eng |
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500 - Science 600 - Technology |
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marc |
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2018 |
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zzz |
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124 |
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Kawaguchi, Kei |
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52 |
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5 |
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Elektronische Aufsätze |
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Kawaguchi, Kei |
| doi_str_mv |
10.1016/j.tice.2018.05.003 |
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570 530 610 |
| title_sort |
mek inhibitor trametinib in combination with gemcitabine regresses a patient-derived orthotopic xenograft (pdox) pancreatic cancer nude mouse model |
| title_auth |
MEK inhibitor trametinib in combination with gemcitabine regresses a patient-derived orthotopic xenograft (PDOX) pancreatic cancer nude mouse model |
| abstract |
• Combination of GEM and TRA seems to have great promise for pancreatic cancer. • Acute toxicity was not associated with the strong efficacy of GEM and TRA. • High level of tumor necrosis and fibrosis was observed in the combination therapy. |
| abstractGer |
• Combination of GEM and TRA seems to have great promise for pancreatic cancer. • Acute toxicity was not associated with the strong efficacy of GEM and TRA. • High level of tumor necrosis and fibrosis was observed in the combination therapy. |
| abstract_unstemmed |
• Combination of GEM and TRA seems to have great promise for pancreatic cancer. • Acute toxicity was not associated with the strong efficacy of GEM and TRA. • High level of tumor necrosis and fibrosis was observed in the combination therapy. |
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GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA |
| title_short |
MEK inhibitor trametinib in combination with gemcitabine regresses a patient-derived orthotopic xenograft (PDOX) pancreatic cancer nude mouse model |
| url |
https://doi.org/10.1016/j.tice.2018.05.003 |
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| author2 |
Igarashi, Kentaro Miyake, Kentaro Lwin, Thinzar M. Miyake, Masuyo Kiyuna, Tasuku Hwang, Ho Kyoung Murakami, Takashi Delong, Jonathan C. Singh, Shree Ram Clary, Bryan Bouvet, Michael Unno, Michiaki Hoffman, Robert M. |
| author2Str |
Igarashi, Kentaro Miyake, Kentaro Lwin, Thinzar M. Miyake, Masuyo Kiyuna, Tasuku Hwang, Ho Kyoung Murakami, Takashi Delong, Jonathan C. Singh, Shree Ram Clary, Bryan Bouvet, Michael Unno, Michiaki Hoffman, Robert M. |
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| doi_str |
10.1016/j.tice.2018.05.003 |
| up_date |
2024-07-06T18:23:46.810Z |
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