Why do proteases mess up with antigen presentation by re-shuffling antigen sequences?
• Non-canonical epitopes have emerged as large part of immunopeptidomes. • Spliced peptides represent 20–30% of the MHC-I immunopeptidome variety. • Peptide splicing by proteasome and other proteases is regulated and efficient. • Peptide splicing efficiency can have implications in defining the immu...
Ausführliche Beschreibung
Autor*in: |
Liepe, Juliane [verfasserIn] |
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Format: |
E-Artikel |
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Sprache: |
Englisch |
Erschienen: |
2018 |
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Umfang: |
6 |
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Übergeordnetes Werk: |
Enthalten in: Formulation of antiretroviral nanocrystals and development into a microneedle delivery system for potential treatment of HIV-associated neurocognitive disorder (HAND) - Abbate, Marco T.A. ELSEVIER, 2023, Philadelphia, Pa |
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Übergeordnetes Werk: |
volume:52 ; year:2018 ; pages:81-86 ; extent:6 |
Links: |
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DOI / URN: |
10.1016/j.coi.2018.04.016 |
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ELV043475086 |
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10.1016/j.coi.2018.04.016 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000000841.pica (DE-627)ELV043475086 (ELSEVIER)S0952-7915(17)30200-5 DE-627 ger DE-627 rakwb eng 610 VZ 15,3 ssgn PHARM DE-84 fid 44.40 bkl Liepe, Juliane verfasserin aut Why do proteases mess up with antigen presentation by re-shuffling antigen sequences? 2018 6 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier • Non-canonical epitopes have emerged as large part of immunopeptidomes. • Spliced peptides represent 20–30% of the MHC-I immunopeptidome variety. • Peptide splicing by proteasome and other proteases is regulated and efficient. • Peptide splicing efficiency can have implications in defining the immunological self. Ovaa, Huib oth Mishto, Michele oth Enthalten in Current Science Abbate, Marco T.A. ELSEVIER Formulation of antiretroviral nanocrystals and development into a microneedle delivery system for potential treatment of HIV-associated neurocognitive disorder (HAND) 2023 Philadelphia, Pa (DE-627)ELV009957871 volume:52 year:2018 pages:81-86 extent:6 https://doi.org/10.1016/j.coi.2018.04.016 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U FID-PHARM SSG-OLC-PHA SSG-OPC-PHA 44.40 Pharmazie Pharmazeutika VZ AR 52 2018 81-86 6 |
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10.1016/j.coi.2018.04.016 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000000841.pica (DE-627)ELV043475086 (ELSEVIER)S0952-7915(17)30200-5 DE-627 ger DE-627 rakwb eng 610 VZ 15,3 ssgn PHARM DE-84 fid 44.40 bkl Liepe, Juliane verfasserin aut Why do proteases mess up with antigen presentation by re-shuffling antigen sequences? 2018 6 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier • Non-canonical epitopes have emerged as large part of immunopeptidomes. • Spliced peptides represent 20–30% of the MHC-I immunopeptidome variety. • Peptide splicing by proteasome and other proteases is regulated and efficient. • Peptide splicing efficiency can have implications in defining the immunological self. Ovaa, Huib oth Mishto, Michele oth Enthalten in Current Science Abbate, Marco T.A. ELSEVIER Formulation of antiretroviral nanocrystals and development into a microneedle delivery system for potential treatment of HIV-associated neurocognitive disorder (HAND) 2023 Philadelphia, Pa (DE-627)ELV009957871 volume:52 year:2018 pages:81-86 extent:6 https://doi.org/10.1016/j.coi.2018.04.016 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U FID-PHARM SSG-OLC-PHA SSG-OPC-PHA 44.40 Pharmazie Pharmazeutika VZ AR 52 2018 81-86 6 |
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10.1016/j.coi.2018.04.016 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000000841.pica (DE-627)ELV043475086 (ELSEVIER)S0952-7915(17)30200-5 DE-627 ger DE-627 rakwb eng 610 VZ 15,3 ssgn PHARM DE-84 fid 44.40 bkl Liepe, Juliane verfasserin aut Why do proteases mess up with antigen presentation by re-shuffling antigen sequences? 2018 6 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier • Non-canonical epitopes have emerged as large part of immunopeptidomes. • Spliced peptides represent 20–30% of the MHC-I immunopeptidome variety. • Peptide splicing by proteasome and other proteases is regulated and efficient. • Peptide splicing efficiency can have implications in defining the immunological self. Ovaa, Huib oth Mishto, Michele oth Enthalten in Current Science Abbate, Marco T.A. ELSEVIER Formulation of antiretroviral nanocrystals and development into a microneedle delivery system for potential treatment of HIV-associated neurocognitive disorder (HAND) 2023 Philadelphia, Pa (DE-627)ELV009957871 volume:52 year:2018 pages:81-86 extent:6 https://doi.org/10.1016/j.coi.2018.04.016 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U FID-PHARM SSG-OLC-PHA SSG-OPC-PHA 44.40 Pharmazie Pharmazeutika VZ AR 52 2018 81-86 6 |
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10.1016/j.coi.2018.04.016 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000000841.pica (DE-627)ELV043475086 (ELSEVIER)S0952-7915(17)30200-5 DE-627 ger DE-627 rakwb eng 610 VZ 15,3 ssgn PHARM DE-84 fid 44.40 bkl Liepe, Juliane verfasserin aut Why do proteases mess up with antigen presentation by re-shuffling antigen sequences? 2018 6 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier • Non-canonical epitopes have emerged as large part of immunopeptidomes. • Spliced peptides represent 20–30% of the MHC-I immunopeptidome variety. • Peptide splicing by proteasome and other proteases is regulated and efficient. • Peptide splicing efficiency can have implications in defining the immunological self. Ovaa, Huib oth Mishto, Michele oth Enthalten in Current Science Abbate, Marco T.A. ELSEVIER Formulation of antiretroviral nanocrystals and development into a microneedle delivery system for potential treatment of HIV-associated neurocognitive disorder (HAND) 2023 Philadelphia, Pa (DE-627)ELV009957871 volume:52 year:2018 pages:81-86 extent:6 https://doi.org/10.1016/j.coi.2018.04.016 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U FID-PHARM SSG-OLC-PHA SSG-OPC-PHA 44.40 Pharmazie Pharmazeutika VZ AR 52 2018 81-86 6 |
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10.1016/j.coi.2018.04.016 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000000841.pica (DE-627)ELV043475086 (ELSEVIER)S0952-7915(17)30200-5 DE-627 ger DE-627 rakwb eng 610 VZ 15,3 ssgn PHARM DE-84 fid 44.40 bkl Liepe, Juliane verfasserin aut Why do proteases mess up with antigen presentation by re-shuffling antigen sequences? 2018 6 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier • Non-canonical epitopes have emerged as large part of immunopeptidomes. • Spliced peptides represent 20–30% of the MHC-I immunopeptidome variety. • Peptide splicing by proteasome and other proteases is regulated and efficient. • Peptide splicing efficiency can have implications in defining the immunological self. Ovaa, Huib oth Mishto, Michele oth Enthalten in Current Science Abbate, Marco T.A. ELSEVIER Formulation of antiretroviral nanocrystals and development into a microneedle delivery system for potential treatment of HIV-associated neurocognitive disorder (HAND) 2023 Philadelphia, Pa (DE-627)ELV009957871 volume:52 year:2018 pages:81-86 extent:6 https://doi.org/10.1016/j.coi.2018.04.016 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U FID-PHARM SSG-OLC-PHA SSG-OPC-PHA 44.40 Pharmazie Pharmazeutika VZ AR 52 2018 81-86 6 |
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why do proteases mess up with antigen presentation by re-shuffling antigen sequences? |
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Why do proteases mess up with antigen presentation by re-shuffling antigen sequences? |
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• Non-canonical epitopes have emerged as large part of immunopeptidomes. • Spliced peptides represent 20–30% of the MHC-I immunopeptidome variety. • Peptide splicing by proteasome and other proteases is regulated and efficient. • Peptide splicing efficiency can have implications in defining the immunological self. |
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• Non-canonical epitopes have emerged as large part of immunopeptidomes. • Spliced peptides represent 20–30% of the MHC-I immunopeptidome variety. • Peptide splicing by proteasome and other proteases is regulated and efficient. • Peptide splicing efficiency can have implications in defining the immunological self. |
abstract_unstemmed |
• Non-canonical epitopes have emerged as large part of immunopeptidomes. • Spliced peptides represent 20–30% of the MHC-I immunopeptidome variety. • Peptide splicing by proteasome and other proteases is regulated and efficient. • Peptide splicing efficiency can have implications in defining the immunological self. |
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Why do proteases mess up with antigen presentation by re-shuffling antigen sequences? |
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