Why do proteases mess up with antigen presentation by re-shuffling antigen sequences?

• Non-canonical epitopes have emerged as large part of immunopeptidomes. • Spliced peptides represent 20–30% of the MHC-I immunopeptidome variety. • Peptide splicing by proteasome and other proteases is regulated and efficient. • Peptide splicing efficiency can have implications in defining the immu...
Ausführliche Beschreibung

Gespeichert in:
Autor*in:

Liepe, Juliane [verfasserIn]

Ovaa, Huib

Mishto, Michele

Format:

E-Artikel

Sprache:

Englisch

Erschienen:

2018

Umfang:

6

Übergeordnetes Werk:

Enthalten in: Formulation of antiretroviral nanocrystals and development into a microneedle delivery system for potential treatment of HIV-associated neurocognitive disorder (HAND) - Abbate, Marco T.A. ELSEVIER, 2023, Philadelphia, Pa

Übergeordnetes Werk:

volume:52 ; year:2018 ; pages:81-86 ; extent:6

Links:

Volltext

DOI / URN:

10.1016/j.coi.2018.04.016

Katalog-ID:

ELV043475086

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