Genetic diversity of the human adenovirus species C DNA polymerase
Human Adenovirus (HAdV) are responsible for severe infections in hematopoietic stem cells transplant (HSCT) recipient, species C viruses being the most commonly observed in this population. There is no approved antiviral treatment yet. Cidofovir (CDV), a cytidine analog, is the most frequently used...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Feghoul, Linda [verfasserIn] |
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E-Artikel |
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Englisch |
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2018 |
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9 |
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Enthalten in: Modeling and prediction of surface roughness for running-in wear using Gauss-Newton algorithm and ANN - Hanief, M. ELSEVIER, 2015transfer abstract, a multidisciplinary journal of antiviral agents, natural host defence mechanisms, interferons and antiviral vaccines : an official publication of the International Society for Antiviral Research, Amsterdam [u.a.] |
|---|---|
| Übergeordnetes Werk: |
volume:156 ; year:2018 ; pages:1-9 ; extent:9 |
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| DOI / URN: |
10.1016/j.antiviral.2018.05.011 |
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| 520 | |a Human Adenovirus (HAdV) are responsible for severe infections in hematopoietic stem cells transplant (HSCT) recipient, species C viruses being the most commonly observed in this population. There is no approved antiviral treatment yet. Cidofovir (CDV), a cytidine analog, is the most frequently used and its lipophilic conjugate, brincidofovir (BCV), is under clinical development. These drugs target the viral DNA polymerase (DNA pol). Little is known about the natural polymorphism of HAdV DNA pol in clinical strains. | ||
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10.1016/j.antiviral.2018.05.011 doi GBV00000000000347.pica (DE-627)ELV043644929 (ELSEVIER)S0166-3542(17)30411-4 DE-627 ger DE-627 rakwb eng 670 VZ 530 VZ 660 VZ 000 150 VZ 54.74 bkl Feghoul, Linda verfasserin aut Genetic diversity of the human adenovirus species C DNA polymerase 2018 9 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Human Adenovirus (HAdV) are responsible for severe infections in hematopoietic stem cells transplant (HSCT) recipient, species C viruses being the most commonly observed in this population. There is no approved antiviral treatment yet. Cidofovir (CDV), a cytidine analog, is the most frequently used and its lipophilic conjugate, brincidofovir (BCV), is under clinical development. These drugs target the viral DNA polymerase (DNA pol). Little is known about the natural polymorphism of HAdV DNA pol in clinical strains. Resistance Elsevier DNA polymerase Elsevier Human adenovirus Elsevier Polymorphism Elsevier Mercier-Delarue, Séverine oth Salmona, Maud oth Ntsiba, Nora oth Dalle, Jean-Hugues oth Baruchel, André oth Klonjkowski, Bernard oth Richardson, Jennifer oth Simon, François oth LeGoff, Jérôme oth Enthalten in Elsevier Science Hanief, M. ELSEVIER Modeling and prediction of surface roughness for running-in wear using Gauss-Newton algorithm and ANN 2015transfer abstract a multidisciplinary journal of antiviral agents, natural host defence mechanisms, interferons and antiviral vaccines : an official publication of the International Society for Antiviral Research Amsterdam [u.a.] (DE-627)ELV012905879 volume:156 year:2018 pages:1-9 extent:9 https://doi.org/10.1016/j.antiviral.2018.05.011 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U 54.74 Maschinelles Sehen VZ AR 156 2018 1-9 9 |
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10.1016/j.antiviral.2018.05.011 doi GBV00000000000347.pica (DE-627)ELV043644929 (ELSEVIER)S0166-3542(17)30411-4 DE-627 ger DE-627 rakwb eng 670 VZ 530 VZ 660 VZ 000 150 VZ 54.74 bkl Feghoul, Linda verfasserin aut Genetic diversity of the human adenovirus species C DNA polymerase 2018 9 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Human Adenovirus (HAdV) are responsible for severe infections in hematopoietic stem cells transplant (HSCT) recipient, species C viruses being the most commonly observed in this population. There is no approved antiviral treatment yet. Cidofovir (CDV), a cytidine analog, is the most frequently used and its lipophilic conjugate, brincidofovir (BCV), is under clinical development. These drugs target the viral DNA polymerase (DNA pol). Little is known about the natural polymorphism of HAdV DNA pol in clinical strains. Resistance Elsevier DNA polymerase Elsevier Human adenovirus Elsevier Polymorphism Elsevier Mercier-Delarue, Séverine oth Salmona, Maud oth Ntsiba, Nora oth Dalle, Jean-Hugues oth Baruchel, André oth Klonjkowski, Bernard oth Richardson, Jennifer oth Simon, François oth LeGoff, Jérôme oth Enthalten in Elsevier Science Hanief, M. ELSEVIER Modeling and prediction of surface roughness for running-in wear using Gauss-Newton algorithm and ANN 2015transfer abstract a multidisciplinary journal of antiviral agents, natural host defence mechanisms, interferons and antiviral vaccines : an official publication of the International Society for Antiviral Research Amsterdam [u.a.] (DE-627)ELV012905879 volume:156 year:2018 pages:1-9 extent:9 https://doi.org/10.1016/j.antiviral.2018.05.011 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U 54.74 Maschinelles Sehen VZ AR 156 2018 1-9 9 |
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Human Adenovirus (HAdV) are responsible for severe infections in hematopoietic stem cells transplant (HSCT) recipient, species C viruses being the most commonly observed in this population. There is no approved antiviral treatment yet. Cidofovir (CDV), a cytidine analog, is the most frequently used and its lipophilic conjugate, brincidofovir (BCV), is under clinical development. These drugs target the viral DNA polymerase (DNA pol). Little is known about the natural polymorphism of HAdV DNA pol in clinical strains. |
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Human Adenovirus (HAdV) are responsible for severe infections in hematopoietic stem cells transplant (HSCT) recipient, species C viruses being the most commonly observed in this population. There is no approved antiviral treatment yet. Cidofovir (CDV), a cytidine analog, is the most frequently used and its lipophilic conjugate, brincidofovir (BCV), is under clinical development. These drugs target the viral DNA polymerase (DNA pol). Little is known about the natural polymorphism of HAdV DNA pol in clinical strains. |
| abstract_unstemmed |
Human Adenovirus (HAdV) are responsible for severe infections in hematopoietic stem cells transplant (HSCT) recipient, species C viruses being the most commonly observed in this population. There is no approved antiviral treatment yet. Cidofovir (CDV), a cytidine analog, is the most frequently used and its lipophilic conjugate, brincidofovir (BCV), is under clinical development. These drugs target the viral DNA polymerase (DNA pol). Little is known about the natural polymorphism of HAdV DNA pol in clinical strains. |
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GBV_USEFLAG_U GBV_ELV SYSFLAG_U |
| title_short |
Genetic diversity of the human adenovirus species C DNA polymerase |
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https://doi.org/10.1016/j.antiviral.2018.05.011 |
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| author2 |
Mercier-Delarue, Séverine Salmona, Maud Ntsiba, Nora Dalle, Jean-Hugues Baruchel, André Klonjkowski, Bernard Richardson, Jennifer Simon, François LeGoff, Jérôme |
| author2Str |
Mercier-Delarue, Séverine Salmona, Maud Ntsiba, Nora Dalle, Jean-Hugues Baruchel, André Klonjkowski, Bernard Richardson, Jennifer Simon, François LeGoff, Jérôme |
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| doi_str |
10.1016/j.antiviral.2018.05.011 |
| up_date |
2024-07-06T19:22:14.058Z |
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1803858722485698560 |
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