Targeting <ce:italic>Helicobacter pylori</ce:italic> urease activity and maturation: In-cell high-throughput approach for drug discovery
Helicobacter pylori is a bacterium strongly associated with gastric cancer. It thrives in the acidic environment of the gastric niche of large portions of the human population using a unique adaptive mechanism that involves the catalytic activity of the nickel-dependent enzyme urease. Targeting urea...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Tarsia, Cinzia [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2018 |
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| Umfang: |
9 |
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| Übergeordnetes Werk: |
Enthalten in: Numerical simulation of the effect of cement particle shapes on capillary pore structures in hardened cement pastes - Liu, Cheng ELSEVIER, 2018, BBA, Amsterdam [u.a.] |
|---|---|
| Übergeordnetes Werk: |
volume:1862 ; year:2018 ; number:10 ; pages:2245-2253 ; extent:9 |
| Links: |
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| DOI / URN: |
10.1016/j.bbagen.2018.07.020 |
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| 520 | |a Helicobacter pylori is a bacterium strongly associated with gastric cancer. It thrives in the acidic environment of the gastric niche of large portions of the human population using a unique adaptive mechanism that involves the catalytic activity of the nickel-dependent enzyme urease. Targeting urease represents a key strategy for drug design and H. pylori eradication. | ||
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10.1016/j.bbagen.2018.07.020 doi GBV00000000000690.pica (DE-627)ELV043764541 (ELSEVIER)S0304-4165(18)30211-3 DE-627 ger DE-627 rakwb eng 690 VZ 56.45 bkl Tarsia, Cinzia verfasserin aut Targeting <ce:italic>Helicobacter pylori</ce:italic> urease activity and maturation: In-cell high-throughput approach for drug discovery 2018 9 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Helicobacter pylori is a bacterium strongly associated with gastric cancer. It thrives in the acidic environment of the gastric niche of large portions of the human population using a unique adaptive mechanism that involves the catalytic activity of the nickel-dependent enzyme urease. Targeting urease represents a key strategy for drug design and H. pylori eradication. Danielli, Alberto oth Florini, Francesca oth Cinelli, Paolo oth Ciurli, Stefano oth Zambelli, Barbara oth Enthalten in Elsevier Liu, Cheng ELSEVIER Numerical simulation of the effect of cement particle shapes on capillary pore structures in hardened cement pastes 2018 BBA Amsterdam [u.a.] (DE-627)ELV001681907 volume:1862 year:2018 number:10 pages:2245-2253 extent:9 https://doi.org/10.1016/j.bbagen.2018.07.020 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U 56.45 Baustoffkunde VZ AR 1862 2018 10 2245-2253 9 |
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10.1016/j.bbagen.2018.07.020 doi GBV00000000000690.pica (DE-627)ELV043764541 (ELSEVIER)S0304-4165(18)30211-3 DE-627 ger DE-627 rakwb eng 690 VZ 56.45 bkl Tarsia, Cinzia verfasserin aut Targeting <ce:italic>Helicobacter pylori</ce:italic> urease activity and maturation: In-cell high-throughput approach for drug discovery 2018 9 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Helicobacter pylori is a bacterium strongly associated with gastric cancer. It thrives in the acidic environment of the gastric niche of large portions of the human population using a unique adaptive mechanism that involves the catalytic activity of the nickel-dependent enzyme urease. Targeting urease represents a key strategy for drug design and H. pylori eradication. Danielli, Alberto oth Florini, Francesca oth Cinelli, Paolo oth Ciurli, Stefano oth Zambelli, Barbara oth Enthalten in Elsevier Liu, Cheng ELSEVIER Numerical simulation of the effect of cement particle shapes on capillary pore structures in hardened cement pastes 2018 BBA Amsterdam [u.a.] (DE-627)ELV001681907 volume:1862 year:2018 number:10 pages:2245-2253 extent:9 https://doi.org/10.1016/j.bbagen.2018.07.020 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U 56.45 Baustoffkunde VZ AR 1862 2018 10 2245-2253 9 |
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10.1016/j.bbagen.2018.07.020 doi GBV00000000000690.pica (DE-627)ELV043764541 (ELSEVIER)S0304-4165(18)30211-3 DE-627 ger DE-627 rakwb eng 690 VZ 56.45 bkl Tarsia, Cinzia verfasserin aut Targeting <ce:italic>Helicobacter pylori</ce:italic> urease activity and maturation: In-cell high-throughput approach for drug discovery 2018 9 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Helicobacter pylori is a bacterium strongly associated with gastric cancer. It thrives in the acidic environment of the gastric niche of large portions of the human population using a unique adaptive mechanism that involves the catalytic activity of the nickel-dependent enzyme urease. Targeting urease represents a key strategy for drug design and H. pylori eradication. Danielli, Alberto oth Florini, Francesca oth Cinelli, Paolo oth Ciurli, Stefano oth Zambelli, Barbara oth Enthalten in Elsevier Liu, Cheng ELSEVIER Numerical simulation of the effect of cement particle shapes on capillary pore structures in hardened cement pastes 2018 BBA Amsterdam [u.a.] (DE-627)ELV001681907 volume:1862 year:2018 number:10 pages:2245-2253 extent:9 https://doi.org/10.1016/j.bbagen.2018.07.020 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U 56.45 Baustoffkunde VZ AR 1862 2018 10 2245-2253 9 |
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10.1016/j.bbagen.2018.07.020 doi GBV00000000000690.pica (DE-627)ELV043764541 (ELSEVIER)S0304-4165(18)30211-3 DE-627 ger DE-627 rakwb eng 690 VZ 56.45 bkl Tarsia, Cinzia verfasserin aut Targeting <ce:italic>Helicobacter pylori</ce:italic> urease activity and maturation: In-cell high-throughput approach for drug discovery 2018 9 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Helicobacter pylori is a bacterium strongly associated with gastric cancer. It thrives in the acidic environment of the gastric niche of large portions of the human population using a unique adaptive mechanism that involves the catalytic activity of the nickel-dependent enzyme urease. Targeting urease represents a key strategy for drug design and H. pylori eradication. Danielli, Alberto oth Florini, Francesca oth Cinelli, Paolo oth Ciurli, Stefano oth Zambelli, Barbara oth Enthalten in Elsevier Liu, Cheng ELSEVIER Numerical simulation of the effect of cement particle shapes on capillary pore structures in hardened cement pastes 2018 BBA Amsterdam [u.a.] (DE-627)ELV001681907 volume:1862 year:2018 number:10 pages:2245-2253 extent:9 https://doi.org/10.1016/j.bbagen.2018.07.020 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U 56.45 Baustoffkunde VZ AR 1862 2018 10 2245-2253 9 |
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10.1016/j.bbagen.2018.07.020 doi GBV00000000000690.pica (DE-627)ELV043764541 (ELSEVIER)S0304-4165(18)30211-3 DE-627 ger DE-627 rakwb eng 690 VZ 56.45 bkl Tarsia, Cinzia verfasserin aut Targeting <ce:italic>Helicobacter pylori</ce:italic> urease activity and maturation: In-cell high-throughput approach for drug discovery 2018 9 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Helicobacter pylori is a bacterium strongly associated with gastric cancer. It thrives in the acidic environment of the gastric niche of large portions of the human population using a unique adaptive mechanism that involves the catalytic activity of the nickel-dependent enzyme urease. Targeting urease represents a key strategy for drug design and H. pylori eradication. Danielli, Alberto oth Florini, Francesca oth Cinelli, Paolo oth Ciurli, Stefano oth Zambelli, Barbara oth Enthalten in Elsevier Liu, Cheng ELSEVIER Numerical simulation of the effect of cement particle shapes on capillary pore structures in hardened cement pastes 2018 BBA Amsterdam [u.a.] (DE-627)ELV001681907 volume:1862 year:2018 number:10 pages:2245-2253 extent:9 https://doi.org/10.1016/j.bbagen.2018.07.020 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U 56.45 Baustoffkunde VZ AR 1862 2018 10 2245-2253 9 |
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Helicobacter pylori is a bacterium strongly associated with gastric cancer. It thrives in the acidic environment of the gastric niche of large portions of the human population using a unique adaptive mechanism that involves the catalytic activity of the nickel-dependent enzyme urease. Targeting urease represents a key strategy for drug design and H. pylori eradication. |
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Helicobacter pylori is a bacterium strongly associated with gastric cancer. It thrives in the acidic environment of the gastric niche of large portions of the human population using a unique adaptive mechanism that involves the catalytic activity of the nickel-dependent enzyme urease. Targeting urease represents a key strategy for drug design and H. pylori eradication. |
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<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">ELV043764541</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230624105002.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">181113s2018 xx |||||o 00| ||eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1016/j.bbagen.2018.07.020</subfield><subfield code="2">doi</subfield></datafield><datafield tag="028" ind1="5" ind2="2"><subfield code="a">GBV00000000000690.pica</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)ELV043764541</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(ELSEVIER)S0304-4165(18)30211-3</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="082" ind1="0" ind2="4"><subfield code="a">690</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">56.45</subfield><subfield code="2">bkl</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Tarsia, Cinzia</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Targeting <ce:italic>Helicobacter pylori</ce:italic> urease activity and maturation: In-cell high-throughput approach for drug discovery</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2018</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">9</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zzz</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">z</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zu</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Helicobacter pylori is a bacterium strongly associated with gastric cancer. 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