The bacterial community and local lymphocyte response are markedly different in patients with recurrent tonsillitis compared to obstructive sleep apnoea
Obstructive sleep apnea (OSA) is now a more common indication for tonsillectomy than recurrent tonsillitis (RT) [1,2]. Few studies have addressed possible differences in pathogenesis between these two conditions. Children with RT and OSA are often being treated in the community with multiple courses...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Johnston, James [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2018transfer abstract |
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| Schlagwörter: |
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| Umfang: |
8 |
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| Übergeordnetes Werk: |
Enthalten in: Investigation of structural analogs of hydroxychloroquine for SARS-CoV-2 main protease (Mpro): A computational drug discovery study - Reyaz, Saima ELSEVIER, 2021, Amsterdam [u.a.] |
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| Übergeordnetes Werk: |
volume:113 ; year:2018 ; pages:281-288 ; extent:8 |
| Links: |
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| DOI / URN: |
10.1016/j.ijporl.2018.07.041 |
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ELV043924921 |
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| 245 | 1 | 4 | |a The bacterial community and local lymphocyte response are markedly different in patients with recurrent tonsillitis compared to obstructive sleep apnoea |
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| 520 | |a Obstructive sleep apnea (OSA) is now a more common indication for tonsillectomy than recurrent tonsillitis (RT) [1,2]. Few studies have addressed possible differences in pathogenesis between these two conditions. Children with RT and OSA are often being treated in the community with multiple courses of antibiotics before surgery. Current understanding of the role of bacteria in disorders of the tonsils is mainly based on the culture of tonsil swabs. Swab cultures reflect only a very small fraction of the bacteria present on the mucosal surface and may not represent the bacterial communities within the tonsil crypts [3,4]. This study aimed to evaluate the local lymphocyte response and associations with bacterial community composition using molecular techniques of the tonsils removed from children for RT or OSA. | ||
| 520 | |a Obstructive sleep apnea (OSA) is now a more common indication for tonsillectomy than recurrent tonsillitis (RT) [1,2]. Few studies have addressed possible differences in pathogenesis between these two conditions. Children with RT and OSA are often being treated in the community with multiple courses of antibiotics before surgery. Current understanding of the role of bacteria in disorders of the tonsils is mainly based on the culture of tonsil swabs. Swab cultures reflect only a very small fraction of the bacteria present on the mucosal surface and may not represent the bacterial communities within the tonsil crypts [3,4]. This study aimed to evaluate the local lymphocyte response and associations with bacterial community composition using molecular techniques of the tonsils removed from children for RT or OSA. | ||
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| 650 | 7 | |a Microbiota |2 Elsevier | |
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| 650 | 7 | |a Lymphocytes |2 Elsevier | |
| 650 | 7 | |a Histology |2 Elsevier | |
| 650 | 7 | |a Adenotonsillectomy |2 Elsevier | |
| 650 | 7 | |a Obstructive sleep apnea |2 Elsevier | |
| 700 | 1 | |a Hoggard, Michael |4 oth | |
| 700 | 1 | |a Biswas, Kristi |4 oth | |
| 700 | 1 | |a Astudillo‐García, Carmen |4 oth | |
| 700 | 1 | |a Waldvogel-Thurlow, Sharon |4 oth | |
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| 700 | 1 | |a Douglas, Richard G. |4 oth | |
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10.1016/j.ijporl.2018.07.041 doi GBV00000000000406.pica (DE-627)ELV043924921 (ELSEVIER)S0165-5876(18)30362-8 DE-627 ger DE-627 rakwb eng 540 004 VZ 35.06 bkl Johnston, James verfasserin aut The bacterial community and local lymphocyte response are markedly different in patients with recurrent tonsillitis compared to obstructive sleep apnoea 2018transfer abstract 8 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Obstructive sleep apnea (OSA) is now a more common indication for tonsillectomy than recurrent tonsillitis (RT) [1,2]. Few studies have addressed possible differences in pathogenesis between these two conditions. Children with RT and OSA are often being treated in the community with multiple courses of antibiotics before surgery. Current understanding of the role of bacteria in disorders of the tonsils is mainly based on the culture of tonsil swabs. Swab cultures reflect only a very small fraction of the bacteria present on the mucosal surface and may not represent the bacterial communities within the tonsil crypts [3,4]. This study aimed to evaluate the local lymphocyte response and associations with bacterial community composition using molecular techniques of the tonsils removed from children for RT or OSA. Obstructive sleep apnea (OSA) is now a more common indication for tonsillectomy than recurrent tonsillitis (RT) [1,2]. Few studies have addressed possible differences in pathogenesis between these two conditions. Children with RT and OSA are often being treated in the community with multiple courses of antibiotics before surgery. Current understanding of the role of bacteria in disorders of the tonsils is mainly based on the culture of tonsil swabs. Swab cultures reflect only a very small fraction of the bacteria present on the mucosal surface and may not represent the bacterial communities within the tonsil crypts [3,4]. This study aimed to evaluate the local lymphocyte response and associations with bacterial community composition using molecular techniques of the tonsils removed from children for RT or OSA. Adenoid Elsevier Microbiota Elsevier Tonsil Elsevier Lymphocytes Elsevier Histology Elsevier Adenotonsillectomy Elsevier Obstructive sleep apnea Elsevier Hoggard, Michael oth Biswas, Kristi oth Astudillo‐García, Carmen oth Waldvogel-Thurlow, Sharon oth Radcliff, Fiona J. oth Mahadevan, Murali oth Douglas, Richard G. oth Enthalten in Elsevier Science Reyaz, Saima ELSEVIER Investigation of structural analogs of hydroxychloroquine for SARS-CoV-2 main protease (Mpro): A computational drug discovery study 2021 Amsterdam [u.a.] (DE-627)ELV006862241 volume:113 year:2018 pages:281-288 extent:8 https://doi.org/10.1016/j.ijporl.2018.07.041 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 35.06 Computeranwendungen Chemie VZ AR 113 2018 281-288 8 |
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10.1016/j.ijporl.2018.07.041 doi GBV00000000000406.pica (DE-627)ELV043924921 (ELSEVIER)S0165-5876(18)30362-8 DE-627 ger DE-627 rakwb eng 540 004 VZ 35.06 bkl Johnston, James verfasserin aut The bacterial community and local lymphocyte response are markedly different in patients with recurrent tonsillitis compared to obstructive sleep apnoea 2018transfer abstract 8 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Obstructive sleep apnea (OSA) is now a more common indication for tonsillectomy than recurrent tonsillitis (RT) [1,2]. Few studies have addressed possible differences in pathogenesis between these two conditions. Children with RT and OSA are often being treated in the community with multiple courses of antibiotics before surgery. Current understanding of the role of bacteria in disorders of the tonsils is mainly based on the culture of tonsil swabs. Swab cultures reflect only a very small fraction of the bacteria present on the mucosal surface and may not represent the bacterial communities within the tonsil crypts [3,4]. This study aimed to evaluate the local lymphocyte response and associations with bacterial community composition using molecular techniques of the tonsils removed from children for RT or OSA. Obstructive sleep apnea (OSA) is now a more common indication for tonsillectomy than recurrent tonsillitis (RT) [1,2]. Few studies have addressed possible differences in pathogenesis between these two conditions. Children with RT and OSA are often being treated in the community with multiple courses of antibiotics before surgery. Current understanding of the role of bacteria in disorders of the tonsils is mainly based on the culture of tonsil swabs. Swab cultures reflect only a very small fraction of the bacteria present on the mucosal surface and may not represent the bacterial communities within the tonsil crypts [3,4]. This study aimed to evaluate the local lymphocyte response and associations with bacterial community composition using molecular techniques of the tonsils removed from children for RT or OSA. Adenoid Elsevier Microbiota Elsevier Tonsil Elsevier Lymphocytes Elsevier Histology Elsevier Adenotonsillectomy Elsevier Obstructive sleep apnea Elsevier Hoggard, Michael oth Biswas, Kristi oth Astudillo‐García, Carmen oth Waldvogel-Thurlow, Sharon oth Radcliff, Fiona J. oth Mahadevan, Murali oth Douglas, Richard G. oth Enthalten in Elsevier Science Reyaz, Saima ELSEVIER Investigation of structural analogs of hydroxychloroquine for SARS-CoV-2 main protease (Mpro): A computational drug discovery study 2021 Amsterdam [u.a.] (DE-627)ELV006862241 volume:113 year:2018 pages:281-288 extent:8 https://doi.org/10.1016/j.ijporl.2018.07.041 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 35.06 Computeranwendungen Chemie VZ AR 113 2018 281-288 8 |
| allfields_unstemmed |
10.1016/j.ijporl.2018.07.041 doi GBV00000000000406.pica (DE-627)ELV043924921 (ELSEVIER)S0165-5876(18)30362-8 DE-627 ger DE-627 rakwb eng 540 004 VZ 35.06 bkl Johnston, James verfasserin aut The bacterial community and local lymphocyte response are markedly different in patients with recurrent tonsillitis compared to obstructive sleep apnoea 2018transfer abstract 8 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Obstructive sleep apnea (OSA) is now a more common indication for tonsillectomy than recurrent tonsillitis (RT) [1,2]. Few studies have addressed possible differences in pathogenesis between these two conditions. Children with RT and OSA are often being treated in the community with multiple courses of antibiotics before surgery. Current understanding of the role of bacteria in disorders of the tonsils is mainly based on the culture of tonsil swabs. Swab cultures reflect only a very small fraction of the bacteria present on the mucosal surface and may not represent the bacterial communities within the tonsil crypts [3,4]. This study aimed to evaluate the local lymphocyte response and associations with bacterial community composition using molecular techniques of the tonsils removed from children for RT or OSA. Obstructive sleep apnea (OSA) is now a more common indication for tonsillectomy than recurrent tonsillitis (RT) [1,2]. Few studies have addressed possible differences in pathogenesis between these two conditions. Children with RT and OSA are often being treated in the community with multiple courses of antibiotics before surgery. Current understanding of the role of bacteria in disorders of the tonsils is mainly based on the culture of tonsil swabs. Swab cultures reflect only a very small fraction of the bacteria present on the mucosal surface and may not represent the bacterial communities within the tonsil crypts [3,4]. This study aimed to evaluate the local lymphocyte response and associations with bacterial community composition using molecular techniques of the tonsils removed from children for RT or OSA. Adenoid Elsevier Microbiota Elsevier Tonsil Elsevier Lymphocytes Elsevier Histology Elsevier Adenotonsillectomy Elsevier Obstructive sleep apnea Elsevier Hoggard, Michael oth Biswas, Kristi oth Astudillo‐García, Carmen oth Waldvogel-Thurlow, Sharon oth Radcliff, Fiona J. oth Mahadevan, Murali oth Douglas, Richard G. oth Enthalten in Elsevier Science Reyaz, Saima ELSEVIER Investigation of structural analogs of hydroxychloroquine for SARS-CoV-2 main protease (Mpro): A computational drug discovery study 2021 Amsterdam [u.a.] (DE-627)ELV006862241 volume:113 year:2018 pages:281-288 extent:8 https://doi.org/10.1016/j.ijporl.2018.07.041 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 35.06 Computeranwendungen Chemie VZ AR 113 2018 281-288 8 |
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10.1016/j.ijporl.2018.07.041 doi GBV00000000000406.pica (DE-627)ELV043924921 (ELSEVIER)S0165-5876(18)30362-8 DE-627 ger DE-627 rakwb eng 540 004 VZ 35.06 bkl Johnston, James verfasserin aut The bacterial community and local lymphocyte response are markedly different in patients with recurrent tonsillitis compared to obstructive sleep apnoea 2018transfer abstract 8 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Obstructive sleep apnea (OSA) is now a more common indication for tonsillectomy than recurrent tonsillitis (RT) [1,2]. Few studies have addressed possible differences in pathogenesis between these two conditions. Children with RT and OSA are often being treated in the community with multiple courses of antibiotics before surgery. Current understanding of the role of bacteria in disorders of the tonsils is mainly based on the culture of tonsil swabs. Swab cultures reflect only a very small fraction of the bacteria present on the mucosal surface and may not represent the bacterial communities within the tonsil crypts [3,4]. This study aimed to evaluate the local lymphocyte response and associations with bacterial community composition using molecular techniques of the tonsils removed from children for RT or OSA. Obstructive sleep apnea (OSA) is now a more common indication for tonsillectomy than recurrent tonsillitis (RT) [1,2]. Few studies have addressed possible differences in pathogenesis between these two conditions. Children with RT and OSA are often being treated in the community with multiple courses of antibiotics before surgery. Current understanding of the role of bacteria in disorders of the tonsils is mainly based on the culture of tonsil swabs. Swab cultures reflect only a very small fraction of the bacteria present on the mucosal surface and may not represent the bacterial communities within the tonsil crypts [3,4]. This study aimed to evaluate the local lymphocyte response and associations with bacterial community composition using molecular techniques of the tonsils removed from children for RT or OSA. Adenoid Elsevier Microbiota Elsevier Tonsil Elsevier Lymphocytes Elsevier Histology Elsevier Adenotonsillectomy Elsevier Obstructive sleep apnea Elsevier Hoggard, Michael oth Biswas, Kristi oth Astudillo‐García, Carmen oth Waldvogel-Thurlow, Sharon oth Radcliff, Fiona J. oth Mahadevan, Murali oth Douglas, Richard G. oth Enthalten in Elsevier Science Reyaz, Saima ELSEVIER Investigation of structural analogs of hydroxychloroquine for SARS-CoV-2 main protease (Mpro): A computational drug discovery study 2021 Amsterdam [u.a.] (DE-627)ELV006862241 volume:113 year:2018 pages:281-288 extent:8 https://doi.org/10.1016/j.ijporl.2018.07.041 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 35.06 Computeranwendungen Chemie VZ AR 113 2018 281-288 8 |
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10.1016/j.ijporl.2018.07.041 doi GBV00000000000406.pica (DE-627)ELV043924921 (ELSEVIER)S0165-5876(18)30362-8 DE-627 ger DE-627 rakwb eng 540 004 VZ 35.06 bkl Johnston, James verfasserin aut The bacterial community and local lymphocyte response are markedly different in patients with recurrent tonsillitis compared to obstructive sleep apnoea 2018transfer abstract 8 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Obstructive sleep apnea (OSA) is now a more common indication for tonsillectomy than recurrent tonsillitis (RT) [1,2]. Few studies have addressed possible differences in pathogenesis between these two conditions. Children with RT and OSA are often being treated in the community with multiple courses of antibiotics before surgery. Current understanding of the role of bacteria in disorders of the tonsils is mainly based on the culture of tonsil swabs. Swab cultures reflect only a very small fraction of the bacteria present on the mucosal surface and may not represent the bacterial communities within the tonsil crypts [3,4]. This study aimed to evaluate the local lymphocyte response and associations with bacterial community composition using molecular techniques of the tonsils removed from children for RT or OSA. Obstructive sleep apnea (OSA) is now a more common indication for tonsillectomy than recurrent tonsillitis (RT) [1,2]. Few studies have addressed possible differences in pathogenesis between these two conditions. Children with RT and OSA are often being treated in the community with multiple courses of antibiotics before surgery. Current understanding of the role of bacteria in disorders of the tonsils is mainly based on the culture of tonsil swabs. Swab cultures reflect only a very small fraction of the bacteria present on the mucosal surface and may not represent the bacterial communities within the tonsil crypts [3,4]. This study aimed to evaluate the local lymphocyte response and associations with bacterial community composition using molecular techniques of the tonsils removed from children for RT or OSA. Adenoid Elsevier Microbiota Elsevier Tonsil Elsevier Lymphocytes Elsevier Histology Elsevier Adenotonsillectomy Elsevier Obstructive sleep apnea Elsevier Hoggard, Michael oth Biswas, Kristi oth Astudillo‐García, Carmen oth Waldvogel-Thurlow, Sharon oth Radcliff, Fiona J. oth Mahadevan, Murali oth Douglas, Richard G. oth Enthalten in Elsevier Science Reyaz, Saima ELSEVIER Investigation of structural analogs of hydroxychloroquine for SARS-CoV-2 main protease (Mpro): A computational drug discovery study 2021 Amsterdam [u.a.] (DE-627)ELV006862241 volume:113 year:2018 pages:281-288 extent:8 https://doi.org/10.1016/j.ijporl.2018.07.041 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 35.06 Computeranwendungen Chemie VZ AR 113 2018 281-288 8 |
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Enthalten in Investigation of structural analogs of hydroxychloroquine for SARS-CoV-2 main protease (Mpro): A computational drug discovery study Amsterdam [u.a.] volume:113 year:2018 pages:281-288 extent:8 |
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Enthalten in Investigation of structural analogs of hydroxychloroquine for SARS-CoV-2 main protease (Mpro): A computational drug discovery study Amsterdam [u.a.] volume:113 year:2018 pages:281-288 extent:8 |
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Investigation of structural analogs of hydroxychloroquine for SARS-CoV-2 main protease (Mpro): A computational drug discovery study |
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Investigation of structural analogs of hydroxychloroquine for SARS-CoV-2 main protease (Mpro): A computational drug discovery study |
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bacterial community and local lymphocyte response are markedly different in patients with recurrent tonsillitis compared to obstructive sleep apnoea |
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The bacterial community and local lymphocyte response are markedly different in patients with recurrent tonsillitis compared to obstructive sleep apnoea |
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Obstructive sleep apnea (OSA) is now a more common indication for tonsillectomy than recurrent tonsillitis (RT) [1,2]. Few studies have addressed possible differences in pathogenesis between these two conditions. Children with RT and OSA are often being treated in the community with multiple courses of antibiotics before surgery. Current understanding of the role of bacteria in disorders of the tonsils is mainly based on the culture of tonsil swabs. Swab cultures reflect only a very small fraction of the bacteria present on the mucosal surface and may not represent the bacterial communities within the tonsil crypts [3,4]. This study aimed to evaluate the local lymphocyte response and associations with bacterial community composition using molecular techniques of the tonsils removed from children for RT or OSA. |
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Obstructive sleep apnea (OSA) is now a more common indication for tonsillectomy than recurrent tonsillitis (RT) [1,2]. Few studies have addressed possible differences in pathogenesis between these two conditions. Children with RT and OSA are often being treated in the community with multiple courses of antibiotics before surgery. Current understanding of the role of bacteria in disorders of the tonsils is mainly based on the culture of tonsil swabs. Swab cultures reflect only a very small fraction of the bacteria present on the mucosal surface and may not represent the bacterial communities within the tonsil crypts [3,4]. This study aimed to evaluate the local lymphocyte response and associations with bacterial community composition using molecular techniques of the tonsils removed from children for RT or OSA. |
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Obstructive sleep apnea (OSA) is now a more common indication for tonsillectomy than recurrent tonsillitis (RT) [1,2]. Few studies have addressed possible differences in pathogenesis between these two conditions. Children with RT and OSA are often being treated in the community with multiple courses of antibiotics before surgery. Current understanding of the role of bacteria in disorders of the tonsils is mainly based on the culture of tonsil swabs. Swab cultures reflect only a very small fraction of the bacteria present on the mucosal surface and may not represent the bacterial communities within the tonsil crypts [3,4]. This study aimed to evaluate the local lymphocyte response and associations with bacterial community composition using molecular techniques of the tonsils removed from children for RT or OSA. |
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The bacterial community and local lymphocyte response are markedly different in patients with recurrent tonsillitis compared to obstructive sleep apnoea |
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Hoggard, Michael Biswas, Kristi Astudillo‐García, Carmen Waldvogel-Thurlow, Sharon Radcliff, Fiona J. Mahadevan, Murali Douglas, Richard G. |
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