The hygiene hypothesis at a glance: Early exposures, immune mechanism and novel therapies
The hygiene hypothesis was proposed almost three decades ago. Nevertheless, its mechanism still remains with relevant controversies. Some studies defend that early exposures during childhood to microbes and parasites are key determinants to prevent allergies and autoimmune diseases; however, other s...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Alexandre-Silva, Gabriel M. [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2018transfer abstract |
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| Schlagwörter: |
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| Umfang: |
11 |
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| Übergeordnetes Werk: |
Enthalten in: Naphthalene based lab-on-a-molecule for fluorimetric and colorimetric sensing of F− and CN− and nitroaromatic explosives - Zhang, Xingyong ELSEVIER, 2017, Amsterdam [u.a.] |
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| Übergeordnetes Werk: |
volume:188 ; year:2018 ; pages:16-26 ; extent:11 |
| Links: |
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| DOI / URN: |
10.1016/j.actatropica.2018.08.032 |
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ELV044268173 |
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| 520 | |a The hygiene hypothesis was proposed almost three decades ago. Nevertheless, its mechanism still remains with relevant controversies. Some studies defend that early exposures during childhood to microbes and parasites are key determinants to prevent allergies and autoimmune diseases; however, other studies demonstrated that these early exposures can even potentiate the clinical scenario of the diseases. Based on several studies covering the influences of microbiome, parasites, related theories and others, this review focuses on recent advances in the hygiene hypothesis field. In addition, the main immunological mechanisms underlying the hygiene hypothesis are also discussed. We also strongly encourage that researchers do not consider the hygiene hypothesis as a theory based strictly on hygiene habits, but a theory combining diverse influences, as illustrated in this review as the hygiene hypothesis net. | ||
| 520 | |a The hygiene hypothesis was proposed almost three decades ago. Nevertheless, its mechanism still remains with relevant controversies. Some studies defend that early exposures during childhood to microbes and parasites are key determinants to prevent allergies and autoimmune diseases; however, other studies demonstrated that these early exposures can even potentiate the clinical scenario of the diseases. Based on several studies covering the influences of microbiome, parasites, related theories and others, this review focuses on recent advances in the hygiene hypothesis field. In addition, the main immunological mechanisms underlying the hygiene hypothesis are also discussed. We also strongly encourage that researchers do not consider the hygiene hypothesis as a theory based strictly on hygiene habits, but a theory combining diverse influences, as illustrated in this review as the hygiene hypothesis net. | ||
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10.1016/j.actatropica.2018.08.032 doi GBV00000000000378.pica (DE-627)ELV044268173 (ELSEVIER)S0001-706X(18)30688-0 DE-627 ger DE-627 rakwb eng 530 VZ 620 VZ 610 VZ 44.91 bkl Alexandre-Silva, Gabriel M. verfasserin aut The hygiene hypothesis at a glance: Early exposures, immune mechanism and novel therapies 2018transfer abstract 11 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier The hygiene hypothesis was proposed almost three decades ago. Nevertheless, its mechanism still remains with relevant controversies. Some studies defend that early exposures during childhood to microbes and parasites are key determinants to prevent allergies and autoimmune diseases; however, other studies demonstrated that these early exposures can even potentiate the clinical scenario of the diseases. Based on several studies covering the influences of microbiome, parasites, related theories and others, this review focuses on recent advances in the hygiene hypothesis field. In addition, the main immunological mechanisms underlying the hygiene hypothesis are also discussed. We also strongly encourage that researchers do not consider the hygiene hypothesis as a theory based strictly on hygiene habits, but a theory combining diverse influences, as illustrated in this review as the hygiene hypothesis net. The hygiene hypothesis was proposed almost three decades ago. Nevertheless, its mechanism still remains with relevant controversies. Some studies defend that early exposures during childhood to microbes and parasites are key determinants to prevent allergies and autoimmune diseases; however, other studies demonstrated that these early exposures can even potentiate the clinical scenario of the diseases. Based on several studies covering the influences of microbiome, parasites, related theories and others, this review focuses on recent advances in the hygiene hypothesis field. In addition, the main immunological mechanisms underlying the hygiene hypothesis are also discussed. We also strongly encourage that researchers do not consider the hygiene hypothesis as a theory based strictly on hygiene habits, but a theory combining diverse influences, as illustrated in this review as the hygiene hypothesis net. Allergy Elsevier Helminthic therapy Elsevier Microbiota therapy Elsevier Hygiene hypothesis Elsevier Parasite Elsevier Autoimmune diseases Elsevier Brito-Souza, Pablo A. oth Oliveira, Ana C.S. oth Cerni, Felipe A. oth Zottich, Umberto oth Pucca, Manuela B. oth Enthalten in Elsevier Zhang, Xingyong ELSEVIER Naphthalene based lab-on-a-molecule for fluorimetric and colorimetric sensing of F− and CN− and nitroaromatic explosives 2017 Amsterdam [u.a.] (DE-627)ELV015210855 volume:188 year:2018 pages:16-26 extent:11 https://doi.org/10.1016/j.actatropica.2018.08.032 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 44.91 Psychiatrie Psychopathologie VZ AR 188 2018 16-26 11 |
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10.1016/j.actatropica.2018.08.032 doi GBV00000000000378.pica (DE-627)ELV044268173 (ELSEVIER)S0001-706X(18)30688-0 DE-627 ger DE-627 rakwb eng 530 VZ 620 VZ 610 VZ 44.91 bkl Alexandre-Silva, Gabriel M. verfasserin aut The hygiene hypothesis at a glance: Early exposures, immune mechanism and novel therapies 2018transfer abstract 11 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier The hygiene hypothesis was proposed almost three decades ago. Nevertheless, its mechanism still remains with relevant controversies. Some studies defend that early exposures during childhood to microbes and parasites are key determinants to prevent allergies and autoimmune diseases; however, other studies demonstrated that these early exposures can even potentiate the clinical scenario of the diseases. Based on several studies covering the influences of microbiome, parasites, related theories and others, this review focuses on recent advances in the hygiene hypothesis field. In addition, the main immunological mechanisms underlying the hygiene hypothesis are also discussed. We also strongly encourage that researchers do not consider the hygiene hypothesis as a theory based strictly on hygiene habits, but a theory combining diverse influences, as illustrated in this review as the hygiene hypothesis net. The hygiene hypothesis was proposed almost three decades ago. Nevertheless, its mechanism still remains with relevant controversies. Some studies defend that early exposures during childhood to microbes and parasites are key determinants to prevent allergies and autoimmune diseases; however, other studies demonstrated that these early exposures can even potentiate the clinical scenario of the diseases. Based on several studies covering the influences of microbiome, parasites, related theories and others, this review focuses on recent advances in the hygiene hypothesis field. In addition, the main immunological mechanisms underlying the hygiene hypothesis are also discussed. We also strongly encourage that researchers do not consider the hygiene hypothesis as a theory based strictly on hygiene habits, but a theory combining diverse influences, as illustrated in this review as the hygiene hypothesis net. Allergy Elsevier Helminthic therapy Elsevier Microbiota therapy Elsevier Hygiene hypothesis Elsevier Parasite Elsevier Autoimmune diseases Elsevier Brito-Souza, Pablo A. oth Oliveira, Ana C.S. oth Cerni, Felipe A. oth Zottich, Umberto oth Pucca, Manuela B. oth Enthalten in Elsevier Zhang, Xingyong ELSEVIER Naphthalene based lab-on-a-molecule for fluorimetric and colorimetric sensing of F− and CN− and nitroaromatic explosives 2017 Amsterdam [u.a.] (DE-627)ELV015210855 volume:188 year:2018 pages:16-26 extent:11 https://doi.org/10.1016/j.actatropica.2018.08.032 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 44.91 Psychiatrie Psychopathologie VZ AR 188 2018 16-26 11 |
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10.1016/j.actatropica.2018.08.032 doi GBV00000000000378.pica (DE-627)ELV044268173 (ELSEVIER)S0001-706X(18)30688-0 DE-627 ger DE-627 rakwb eng 530 VZ 620 VZ 610 VZ 44.91 bkl Alexandre-Silva, Gabriel M. verfasserin aut The hygiene hypothesis at a glance: Early exposures, immune mechanism and novel therapies 2018transfer abstract 11 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier The hygiene hypothesis was proposed almost three decades ago. Nevertheless, its mechanism still remains with relevant controversies. Some studies defend that early exposures during childhood to microbes and parasites are key determinants to prevent allergies and autoimmune diseases; however, other studies demonstrated that these early exposures can even potentiate the clinical scenario of the diseases. Based on several studies covering the influences of microbiome, parasites, related theories and others, this review focuses on recent advances in the hygiene hypothesis field. In addition, the main immunological mechanisms underlying the hygiene hypothesis are also discussed. We also strongly encourage that researchers do not consider the hygiene hypothesis as a theory based strictly on hygiene habits, but a theory combining diverse influences, as illustrated in this review as the hygiene hypothesis net. The hygiene hypothesis was proposed almost three decades ago. Nevertheless, its mechanism still remains with relevant controversies. Some studies defend that early exposures during childhood to microbes and parasites are key determinants to prevent allergies and autoimmune diseases; however, other studies demonstrated that these early exposures can even potentiate the clinical scenario of the diseases. Based on several studies covering the influences of microbiome, parasites, related theories and others, this review focuses on recent advances in the hygiene hypothesis field. In addition, the main immunological mechanisms underlying the hygiene hypothesis are also discussed. We also strongly encourage that researchers do not consider the hygiene hypothesis as a theory based strictly on hygiene habits, but a theory combining diverse influences, as illustrated in this review as the hygiene hypothesis net. Allergy Elsevier Helminthic therapy Elsevier Microbiota therapy Elsevier Hygiene hypothesis Elsevier Parasite Elsevier Autoimmune diseases Elsevier Brito-Souza, Pablo A. oth Oliveira, Ana C.S. oth Cerni, Felipe A. oth Zottich, Umberto oth Pucca, Manuela B. oth Enthalten in Elsevier Zhang, Xingyong ELSEVIER Naphthalene based lab-on-a-molecule for fluorimetric and colorimetric sensing of F− and CN− and nitroaromatic explosives 2017 Amsterdam [u.a.] (DE-627)ELV015210855 volume:188 year:2018 pages:16-26 extent:11 https://doi.org/10.1016/j.actatropica.2018.08.032 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 44.91 Psychiatrie Psychopathologie VZ AR 188 2018 16-26 11 |
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10.1016/j.actatropica.2018.08.032 doi GBV00000000000378.pica (DE-627)ELV044268173 (ELSEVIER)S0001-706X(18)30688-0 DE-627 ger DE-627 rakwb eng 530 VZ 620 VZ 610 VZ 44.91 bkl Alexandre-Silva, Gabriel M. verfasserin aut The hygiene hypothesis at a glance: Early exposures, immune mechanism and novel therapies 2018transfer abstract 11 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier The hygiene hypothesis was proposed almost three decades ago. Nevertheless, its mechanism still remains with relevant controversies. Some studies defend that early exposures during childhood to microbes and parasites are key determinants to prevent allergies and autoimmune diseases; however, other studies demonstrated that these early exposures can even potentiate the clinical scenario of the diseases. Based on several studies covering the influences of microbiome, parasites, related theories and others, this review focuses on recent advances in the hygiene hypothesis field. In addition, the main immunological mechanisms underlying the hygiene hypothesis are also discussed. We also strongly encourage that researchers do not consider the hygiene hypothesis as a theory based strictly on hygiene habits, but a theory combining diverse influences, as illustrated in this review as the hygiene hypothesis net. The hygiene hypothesis was proposed almost three decades ago. Nevertheless, its mechanism still remains with relevant controversies. Some studies defend that early exposures during childhood to microbes and parasites are key determinants to prevent allergies and autoimmune diseases; however, other studies demonstrated that these early exposures can even potentiate the clinical scenario of the diseases. Based on several studies covering the influences of microbiome, parasites, related theories and others, this review focuses on recent advances in the hygiene hypothesis field. In addition, the main immunological mechanisms underlying the hygiene hypothesis are also discussed. We also strongly encourage that researchers do not consider the hygiene hypothesis as a theory based strictly on hygiene habits, but a theory combining diverse influences, as illustrated in this review as the hygiene hypothesis net. Allergy Elsevier Helminthic therapy Elsevier Microbiota therapy Elsevier Hygiene hypothesis Elsevier Parasite Elsevier Autoimmune diseases Elsevier Brito-Souza, Pablo A. oth Oliveira, Ana C.S. oth Cerni, Felipe A. oth Zottich, Umberto oth Pucca, Manuela B. oth Enthalten in Elsevier Zhang, Xingyong ELSEVIER Naphthalene based lab-on-a-molecule for fluorimetric and colorimetric sensing of F− and CN− and nitroaromatic explosives 2017 Amsterdam [u.a.] (DE-627)ELV015210855 volume:188 year:2018 pages:16-26 extent:11 https://doi.org/10.1016/j.actatropica.2018.08.032 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 44.91 Psychiatrie Psychopathologie VZ AR 188 2018 16-26 11 |
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10.1016/j.actatropica.2018.08.032 doi GBV00000000000378.pica (DE-627)ELV044268173 (ELSEVIER)S0001-706X(18)30688-0 DE-627 ger DE-627 rakwb eng 530 VZ 620 VZ 610 VZ 44.91 bkl Alexandre-Silva, Gabriel M. verfasserin aut The hygiene hypothesis at a glance: Early exposures, immune mechanism and novel therapies 2018transfer abstract 11 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier The hygiene hypothesis was proposed almost three decades ago. Nevertheless, its mechanism still remains with relevant controversies. Some studies defend that early exposures during childhood to microbes and parasites are key determinants to prevent allergies and autoimmune diseases; however, other studies demonstrated that these early exposures can even potentiate the clinical scenario of the diseases. Based on several studies covering the influences of microbiome, parasites, related theories and others, this review focuses on recent advances in the hygiene hypothesis field. In addition, the main immunological mechanisms underlying the hygiene hypothesis are also discussed. We also strongly encourage that researchers do not consider the hygiene hypothesis as a theory based strictly on hygiene habits, but a theory combining diverse influences, as illustrated in this review as the hygiene hypothesis net. The hygiene hypothesis was proposed almost three decades ago. Nevertheless, its mechanism still remains with relevant controversies. Some studies defend that early exposures during childhood to microbes and parasites are key determinants to prevent allergies and autoimmune diseases; however, other studies demonstrated that these early exposures can even potentiate the clinical scenario of the diseases. Based on several studies covering the influences of microbiome, parasites, related theories and others, this review focuses on recent advances in the hygiene hypothesis field. In addition, the main immunological mechanisms underlying the hygiene hypothesis are also discussed. We also strongly encourage that researchers do not consider the hygiene hypothesis as a theory based strictly on hygiene habits, but a theory combining diverse influences, as illustrated in this review as the hygiene hypothesis net. Allergy Elsevier Helminthic therapy Elsevier Microbiota therapy Elsevier Hygiene hypothesis Elsevier Parasite Elsevier Autoimmune diseases Elsevier Brito-Souza, Pablo A. oth Oliveira, Ana C.S. oth Cerni, Felipe A. oth Zottich, Umberto oth Pucca, Manuela B. oth Enthalten in Elsevier Zhang, Xingyong ELSEVIER Naphthalene based lab-on-a-molecule for fluorimetric and colorimetric sensing of F− and CN− and nitroaromatic explosives 2017 Amsterdam [u.a.] (DE-627)ELV015210855 volume:188 year:2018 pages:16-26 extent:11 https://doi.org/10.1016/j.actatropica.2018.08.032 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 44.91 Psychiatrie Psychopathologie VZ AR 188 2018 16-26 11 |
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Enthalten in Naphthalene based lab-on-a-molecule for fluorimetric and colorimetric sensing of F− and CN− and nitroaromatic explosives Amsterdam [u.a.] volume:188 year:2018 pages:16-26 extent:11 |
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The hygiene hypothesis was proposed almost three decades ago. Nevertheless, its mechanism still remains with relevant controversies. Some studies defend that early exposures during childhood to microbes and parasites are key determinants to prevent allergies and autoimmune diseases; however, other studies demonstrated that these early exposures can even potentiate the clinical scenario of the diseases. Based on several studies covering the influences of microbiome, parasites, related theories and others, this review focuses on recent advances in the hygiene hypothesis field. In addition, the main immunological mechanisms underlying the hygiene hypothesis are also discussed. We also strongly encourage that researchers do not consider the hygiene hypothesis as a theory based strictly on hygiene habits, but a theory combining diverse influences, as illustrated in this review as the hygiene hypothesis net. |
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The hygiene hypothesis was proposed almost three decades ago. Nevertheless, its mechanism still remains with relevant controversies. Some studies defend that early exposures during childhood to microbes and parasites are key determinants to prevent allergies and autoimmune diseases; however, other studies demonstrated that these early exposures can even potentiate the clinical scenario of the diseases. Based on several studies covering the influences of microbiome, parasites, related theories and others, this review focuses on recent advances in the hygiene hypothesis field. In addition, the main immunological mechanisms underlying the hygiene hypothesis are also discussed. We also strongly encourage that researchers do not consider the hygiene hypothesis as a theory based strictly on hygiene habits, but a theory combining diverse influences, as illustrated in this review as the hygiene hypothesis net. |
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The hygiene hypothesis was proposed almost three decades ago. Nevertheless, its mechanism still remains with relevant controversies. Some studies defend that early exposures during childhood to microbes and parasites are key determinants to prevent allergies and autoimmune diseases; however, other studies demonstrated that these early exposures can even potentiate the clinical scenario of the diseases. Based on several studies covering the influences of microbiome, parasites, related theories and others, this review focuses on recent advances in the hygiene hypothesis field. In addition, the main immunological mechanisms underlying the hygiene hypothesis are also discussed. We also strongly encourage that researchers do not consider the hygiene hypothesis as a theory based strictly on hygiene habits, but a theory combining diverse influences, as illustrated in this review as the hygiene hypothesis net. |
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