Design, synthesis, in vitro and in vivo evaluation, and structure-activity relationship (SAR) discussion of novel dipeptidyl boronic acid proteasome inhibitors as orally available anti-cancer agents for the treatment of multiple myeloma and mechanism studies

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Gespeichert in:
Autor*in:

Lei, Meng [verfasserIn]

Feng, Huayun

Bai, Enhe

Zhou, Hui

Wang, Jia

Shi, Jingmiao

Wang, Xueyuan

Hu, Shihe

Liu, Zhaogang

Zhu, Yongqiang

Format:

E-Artikel

Sprache:

Englisch

Erschienen:

2018

Schlagwörter:

FDA

C-L

SAR

EDCI

MS

DIPEA

CP

IC50

CT-L

AUC

SD

HRMS

NMR

UPP

T-L

T1/2

HOBt

ATP

RP

Umfang:

7

Übergeordnetes Werk:

Enthalten in: A theoretical model of cyberchondria development: Antecedents and intermediate processes - Zheng, Han ELSEVIER, 2021, a Tetrahedron publication for the rapid dissemination of full original research papers and critical reviews on bioorganic chemistry, medicinal chemistry, bioinorganic chemistry and related disciplines, Amsterdam [u.a.]

Übergeordnetes Werk:

volume:26 ; year:2018 ; number:14 ; day:7 ; month:08 ; pages:3975-3981 ; extent:7

Links:

Volltext

DOI / URN:

10.1016/j.bmc.2018.06.020

Katalog-ID:

ELV04482422X

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