New Perspectives on the Pathogenesis of PCOS: Neuroendocrine Origins
Polycystic ovary syndrome (PCOS) is the most common endocrine condition in reproductive-aged women. It is characterized by reproductive, endocrine, metabolic, and psychological features. The cause of PCOS is unknown, thus there is no cure and its management remains suboptimal because it relies on th...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Walters, Kirsty A. [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2018transfer abstract |
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| Schlagwörter: |
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| Umfang: |
12 |
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| Übergeordnetes Werk: |
Enthalten in: The gaze of sleep loss: acute effects of sleep loss on facial perception - van Egmond, L.T. ELSEVIER, 2022, Amsterdam [u.a.] |
|---|---|
| Übergeordnetes Werk: |
volume:29 ; year:2018 ; number:12 ; pages:841-852 ; extent:12 |
| Links: |
|---|
| DOI / URN: |
10.1016/j.tem.2018.08.005 |
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ELV044915063 |
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| 520 | |a Polycystic ovary syndrome (PCOS) is the most common endocrine condition in reproductive-aged women. It is characterized by reproductive, endocrine, metabolic, and psychological features. The cause of PCOS is unknown, thus there is no cure and its management remains suboptimal because it relies on the ad hoc empirical management of symptoms only. We review here the strong support for PCOS having a neuroendocrine origin. In particular, we focus on the role of aberrant hypothalamic–pituitary function and associated hyperandrogenism, and their role as major drivers of the mechanisms underpinning the development of PCOS. This important information now provides a target site and a potential mechanism for the future development of novel, targeted, and mechanism-based effective therapies for the treatment of PCOS. | ||
| 520 | |a Polycystic ovary syndrome (PCOS) is the most common endocrine condition in reproductive-aged women. It is characterized by reproductive, endocrine, metabolic, and psychological features. The cause of PCOS is unknown, thus there is no cure and its management remains suboptimal because it relies on the ad hoc empirical management of symptoms only. We review here the strong support for PCOS having a neuroendocrine origin. In particular, we focus on the role of aberrant hypothalamic–pituitary function and associated hyperandrogenism, and their role as major drivers of the mechanisms underpinning the development of PCOS. This important information now provides a target site and a potential mechanism for the future development of novel, targeted, and mechanism-based effective therapies for the treatment of PCOS. | ||
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10.1016/j.tem.2018.08.005 doi GBV00000000000425.pica (DE-627)ELV044915063 (ELSEVIER)S1043-2760(18)30149-8 DE-627 ger DE-627 rakwb eng 610 VZ 44.90 bkl Walters, Kirsty A. verfasserin aut New Perspectives on the Pathogenesis of PCOS: Neuroendocrine Origins 2018transfer abstract 12 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Polycystic ovary syndrome (PCOS) is the most common endocrine condition in reproductive-aged women. It is characterized by reproductive, endocrine, metabolic, and psychological features. The cause of PCOS is unknown, thus there is no cure and its management remains suboptimal because it relies on the ad hoc empirical management of symptoms only. We review here the strong support for PCOS having a neuroendocrine origin. In particular, we focus on the role of aberrant hypothalamic–pituitary function and associated hyperandrogenism, and their role as major drivers of the mechanisms underpinning the development of PCOS. This important information now provides a target site and a potential mechanism for the future development of novel, targeted, and mechanism-based effective therapies for the treatment of PCOS. Polycystic ovary syndrome (PCOS) is the most common endocrine condition in reproductive-aged women. It is characterized by reproductive, endocrine, metabolic, and psychological features. The cause of PCOS is unknown, thus there is no cure and its management remains suboptimal because it relies on the ad hoc empirical management of symptoms only. We review here the strong support for PCOS having a neuroendocrine origin. In particular, we focus on the role of aberrant hypothalamic–pituitary function and associated hyperandrogenism, and their role as major drivers of the mechanisms underpinning the development of PCOS. This important information now provides a target site and a potential mechanism for the future development of novel, targeted, and mechanism-based effective therapies for the treatment of PCOS. androgen receptor Elsevier hyperandrogenism Elsevier brain Elsevier polycystic ovary syndrome Elsevier Gilchrist, Robert B. oth Ledger, William L. oth Teede, Helena J. oth Handelsman, David J. oth Campbell, Rebecca E. oth Enthalten in Elsevier Science van Egmond, L.T. ELSEVIER The gaze of sleep loss: acute effects of sleep loss on facial perception 2022 Amsterdam [u.a.] (DE-627)ELV008220654 volume:29 year:2018 number:12 pages:841-852 extent:12 https://doi.org/10.1016/j.tem.2018.08.005 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 44.90 Neurologie VZ AR 29 2018 12 841-852 12 |
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10.1016/j.tem.2018.08.005 doi GBV00000000000425.pica (DE-627)ELV044915063 (ELSEVIER)S1043-2760(18)30149-8 DE-627 ger DE-627 rakwb eng 610 VZ 44.90 bkl Walters, Kirsty A. verfasserin aut New Perspectives on the Pathogenesis of PCOS: Neuroendocrine Origins 2018transfer abstract 12 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Polycystic ovary syndrome (PCOS) is the most common endocrine condition in reproductive-aged women. It is characterized by reproductive, endocrine, metabolic, and psychological features. The cause of PCOS is unknown, thus there is no cure and its management remains suboptimal because it relies on the ad hoc empirical management of symptoms only. We review here the strong support for PCOS having a neuroendocrine origin. In particular, we focus on the role of aberrant hypothalamic–pituitary function and associated hyperandrogenism, and their role as major drivers of the mechanisms underpinning the development of PCOS. This important information now provides a target site and a potential mechanism for the future development of novel, targeted, and mechanism-based effective therapies for the treatment of PCOS. Polycystic ovary syndrome (PCOS) is the most common endocrine condition in reproductive-aged women. It is characterized by reproductive, endocrine, metabolic, and psychological features. The cause of PCOS is unknown, thus there is no cure and its management remains suboptimal because it relies on the ad hoc empirical management of symptoms only. We review here the strong support for PCOS having a neuroendocrine origin. In particular, we focus on the role of aberrant hypothalamic–pituitary function and associated hyperandrogenism, and their role as major drivers of the mechanisms underpinning the development of PCOS. This important information now provides a target site and a potential mechanism for the future development of novel, targeted, and mechanism-based effective therapies for the treatment of PCOS. androgen receptor Elsevier hyperandrogenism Elsevier brain Elsevier polycystic ovary syndrome Elsevier Gilchrist, Robert B. oth Ledger, William L. oth Teede, Helena J. oth Handelsman, David J. oth Campbell, Rebecca E. oth Enthalten in Elsevier Science van Egmond, L.T. ELSEVIER The gaze of sleep loss: acute effects of sleep loss on facial perception 2022 Amsterdam [u.a.] (DE-627)ELV008220654 volume:29 year:2018 number:12 pages:841-852 extent:12 https://doi.org/10.1016/j.tem.2018.08.005 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 44.90 Neurologie VZ AR 29 2018 12 841-852 12 |
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10.1016/j.tem.2018.08.005 doi GBV00000000000425.pica (DE-627)ELV044915063 (ELSEVIER)S1043-2760(18)30149-8 DE-627 ger DE-627 rakwb eng 610 VZ 44.90 bkl Walters, Kirsty A. verfasserin aut New Perspectives on the Pathogenesis of PCOS: Neuroendocrine Origins 2018transfer abstract 12 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Polycystic ovary syndrome (PCOS) is the most common endocrine condition in reproductive-aged women. It is characterized by reproductive, endocrine, metabolic, and psychological features. The cause of PCOS is unknown, thus there is no cure and its management remains suboptimal because it relies on the ad hoc empirical management of symptoms only. We review here the strong support for PCOS having a neuroendocrine origin. In particular, we focus on the role of aberrant hypothalamic–pituitary function and associated hyperandrogenism, and their role as major drivers of the mechanisms underpinning the development of PCOS. This important information now provides a target site and a potential mechanism for the future development of novel, targeted, and mechanism-based effective therapies for the treatment of PCOS. Polycystic ovary syndrome (PCOS) is the most common endocrine condition in reproductive-aged women. It is characterized by reproductive, endocrine, metabolic, and psychological features. The cause of PCOS is unknown, thus there is no cure and its management remains suboptimal because it relies on the ad hoc empirical management of symptoms only. We review here the strong support for PCOS having a neuroendocrine origin. In particular, we focus on the role of aberrant hypothalamic–pituitary function and associated hyperandrogenism, and their role as major drivers of the mechanisms underpinning the development of PCOS. This important information now provides a target site and a potential mechanism for the future development of novel, targeted, and mechanism-based effective therapies for the treatment of PCOS. androgen receptor Elsevier hyperandrogenism Elsevier brain Elsevier polycystic ovary syndrome Elsevier Gilchrist, Robert B. oth Ledger, William L. oth Teede, Helena J. oth Handelsman, David J. oth Campbell, Rebecca E. oth Enthalten in Elsevier Science van Egmond, L.T. ELSEVIER The gaze of sleep loss: acute effects of sleep loss on facial perception 2022 Amsterdam [u.a.] (DE-627)ELV008220654 volume:29 year:2018 number:12 pages:841-852 extent:12 https://doi.org/10.1016/j.tem.2018.08.005 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 44.90 Neurologie VZ AR 29 2018 12 841-852 12 |
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10.1016/j.tem.2018.08.005 doi GBV00000000000425.pica (DE-627)ELV044915063 (ELSEVIER)S1043-2760(18)30149-8 DE-627 ger DE-627 rakwb eng 610 VZ 44.90 bkl Walters, Kirsty A. verfasserin aut New Perspectives on the Pathogenesis of PCOS: Neuroendocrine Origins 2018transfer abstract 12 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Polycystic ovary syndrome (PCOS) is the most common endocrine condition in reproductive-aged women. It is characterized by reproductive, endocrine, metabolic, and psychological features. The cause of PCOS is unknown, thus there is no cure and its management remains suboptimal because it relies on the ad hoc empirical management of symptoms only. We review here the strong support for PCOS having a neuroendocrine origin. In particular, we focus on the role of aberrant hypothalamic–pituitary function and associated hyperandrogenism, and their role as major drivers of the mechanisms underpinning the development of PCOS. This important information now provides a target site and a potential mechanism for the future development of novel, targeted, and mechanism-based effective therapies for the treatment of PCOS. Polycystic ovary syndrome (PCOS) is the most common endocrine condition in reproductive-aged women. It is characterized by reproductive, endocrine, metabolic, and psychological features. The cause of PCOS is unknown, thus there is no cure and its management remains suboptimal because it relies on the ad hoc empirical management of symptoms only. We review here the strong support for PCOS having a neuroendocrine origin. In particular, we focus on the role of aberrant hypothalamic–pituitary function and associated hyperandrogenism, and their role as major drivers of the mechanisms underpinning the development of PCOS. This important information now provides a target site and a potential mechanism for the future development of novel, targeted, and mechanism-based effective therapies for the treatment of PCOS. androgen receptor Elsevier hyperandrogenism Elsevier brain Elsevier polycystic ovary syndrome Elsevier Gilchrist, Robert B. oth Ledger, William L. oth Teede, Helena J. oth Handelsman, David J. oth Campbell, Rebecca E. oth Enthalten in Elsevier Science van Egmond, L.T. ELSEVIER The gaze of sleep loss: acute effects of sleep loss on facial perception 2022 Amsterdam [u.a.] (DE-627)ELV008220654 volume:29 year:2018 number:12 pages:841-852 extent:12 https://doi.org/10.1016/j.tem.2018.08.005 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 44.90 Neurologie VZ AR 29 2018 12 841-852 12 |
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10.1016/j.tem.2018.08.005 doi GBV00000000000425.pica (DE-627)ELV044915063 (ELSEVIER)S1043-2760(18)30149-8 DE-627 ger DE-627 rakwb eng 610 VZ 44.90 bkl Walters, Kirsty A. verfasserin aut New Perspectives on the Pathogenesis of PCOS: Neuroendocrine Origins 2018transfer abstract 12 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Polycystic ovary syndrome (PCOS) is the most common endocrine condition in reproductive-aged women. It is characterized by reproductive, endocrine, metabolic, and psychological features. The cause of PCOS is unknown, thus there is no cure and its management remains suboptimal because it relies on the ad hoc empirical management of symptoms only. We review here the strong support for PCOS having a neuroendocrine origin. In particular, we focus on the role of aberrant hypothalamic–pituitary function and associated hyperandrogenism, and their role as major drivers of the mechanisms underpinning the development of PCOS. This important information now provides a target site and a potential mechanism for the future development of novel, targeted, and mechanism-based effective therapies for the treatment of PCOS. Polycystic ovary syndrome (PCOS) is the most common endocrine condition in reproductive-aged women. It is characterized by reproductive, endocrine, metabolic, and psychological features. The cause of PCOS is unknown, thus there is no cure and its management remains suboptimal because it relies on the ad hoc empirical management of symptoms only. We review here the strong support for PCOS having a neuroendocrine origin. In particular, we focus on the role of aberrant hypothalamic–pituitary function and associated hyperandrogenism, and their role as major drivers of the mechanisms underpinning the development of PCOS. This important information now provides a target site and a potential mechanism for the future development of novel, targeted, and mechanism-based effective therapies for the treatment of PCOS. androgen receptor Elsevier hyperandrogenism Elsevier brain Elsevier polycystic ovary syndrome Elsevier Gilchrist, Robert B. oth Ledger, William L. oth Teede, Helena J. oth Handelsman, David J. oth Campbell, Rebecca E. oth Enthalten in Elsevier Science van Egmond, L.T. ELSEVIER The gaze of sleep loss: acute effects of sleep loss on facial perception 2022 Amsterdam [u.a.] (DE-627)ELV008220654 volume:29 year:2018 number:12 pages:841-852 extent:12 https://doi.org/10.1016/j.tem.2018.08.005 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 44.90 Neurologie VZ AR 29 2018 12 841-852 12 |
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New Perspectives on the Pathogenesis of PCOS: Neuroendocrine Origins |
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Walters, Kirsty A. |
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The gaze of sleep loss: acute effects of sleep loss on facial perception |
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The gaze of sleep loss: acute effects of sleep loss on facial perception |
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eng |
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Walters, Kirsty A. |
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Elektronische Aufsätze |
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Walters, Kirsty A. |
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10.1016/j.tem.2018.08.005 |
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610 |
| title_sort |
new perspectives on the pathogenesis of pcos: neuroendocrine origins |
| title_auth |
New Perspectives on the Pathogenesis of PCOS: Neuroendocrine Origins |
| abstract |
Polycystic ovary syndrome (PCOS) is the most common endocrine condition in reproductive-aged women. It is characterized by reproductive, endocrine, metabolic, and psychological features. The cause of PCOS is unknown, thus there is no cure and its management remains suboptimal because it relies on the ad hoc empirical management of symptoms only. We review here the strong support for PCOS having a neuroendocrine origin. In particular, we focus on the role of aberrant hypothalamic–pituitary function and associated hyperandrogenism, and their role as major drivers of the mechanisms underpinning the development of PCOS. This important information now provides a target site and a potential mechanism for the future development of novel, targeted, and mechanism-based effective therapies for the treatment of PCOS. |
| abstractGer |
Polycystic ovary syndrome (PCOS) is the most common endocrine condition in reproductive-aged women. It is characterized by reproductive, endocrine, metabolic, and psychological features. The cause of PCOS is unknown, thus there is no cure and its management remains suboptimal because it relies on the ad hoc empirical management of symptoms only. We review here the strong support for PCOS having a neuroendocrine origin. In particular, we focus on the role of aberrant hypothalamic–pituitary function and associated hyperandrogenism, and their role as major drivers of the mechanisms underpinning the development of PCOS. This important information now provides a target site and a potential mechanism for the future development of novel, targeted, and mechanism-based effective therapies for the treatment of PCOS. |
| abstract_unstemmed |
Polycystic ovary syndrome (PCOS) is the most common endocrine condition in reproductive-aged women. It is characterized by reproductive, endocrine, metabolic, and psychological features. The cause of PCOS is unknown, thus there is no cure and its management remains suboptimal because it relies on the ad hoc empirical management of symptoms only. We review here the strong support for PCOS having a neuroendocrine origin. In particular, we focus on the role of aberrant hypothalamic–pituitary function and associated hyperandrogenism, and their role as major drivers of the mechanisms underpinning the development of PCOS. This important information now provides a target site and a potential mechanism for the future development of novel, targeted, and mechanism-based effective therapies for the treatment of PCOS. |
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| title_short |
New Perspectives on the Pathogenesis of PCOS: Neuroendocrine Origins |
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https://doi.org/10.1016/j.tem.2018.08.005 |
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| author2 |
Gilchrist, Robert B. Ledger, William L. Teede, Helena J. Handelsman, David J. Campbell, Rebecca E. |
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Gilchrist, Robert B. Ledger, William L. Teede, Helena J. Handelsman, David J. Campbell, Rebecca E. |
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| up_date |
2024-07-06T22:44:24.375Z |
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