Microglia have a protective role in viral encephalitis-induced seizure development and hippocampal damage
• Microglia’s role in encephalitis and its long-term consequences is incompletely understood. • We studied consequences of microglia depletion in a picorna virus model of epilepsy in mice. • Data indicate that microglia limits virus distribution and persistence, likely via T cell crosstalk. • Microg...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Waltl, Inken [verfasserIn] |
|---|
| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2018 |
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| Schlagwörter: |
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| Umfang: |
19 |
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| Übergeordnetes Werk: |
Enthalten in: A new poly(3,4-ethylenedioxythiophene)-poly (styrene sulfonate)/nickel oxide nanoparticles (PEDOT:PSS/NiO) thermoelectric system with a promising thermoelectric power factor - Al Naim, Abdullah F. ELSEVIER, 2022, Orlando, Fla. [u.a.] |
|---|---|
| Übergeordnetes Werk: |
volume:74 ; year:2018 ; pages:186-204 ; extent:19 |
| Links: |
|---|
| DOI / URN: |
10.1016/j.bbi.2018.09.006 |
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| 520 | |a • Microglia’s role in encephalitis and its long-term consequences is incompletely understood. • We studied consequences of microglia depletion in a picorna virus model of epilepsy in mice. • Data indicate that microglia limits virus distribution and persistence, likely via T cell crosstalk. • Microglia depletion exacerbated seizure occurrence and hippocampal and spinal cord damage. • Specific depletion of microglia helps to parse out their exact roles in viral encephalitis. | ||
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10.1016/j.bbi.2018.09.006 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000001886.pica (DE-627)ELV045167702 (ELSEVIER)S0889-1591(18)30356-8 DE-627 ger DE-627 rakwb eng 540 VZ 35.00 bkl 51.50 bkl 58.00 bkl Waltl, Inken verfasserin aut Microglia have a protective role in viral encephalitis-induced seizure development and hippocampal damage 2018 19 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier • Microglia’s role in encephalitis and its long-term consequences is incompletely understood. • We studied consequences of microglia depletion in a picorna virus model of epilepsy in mice. • Data indicate that microglia limits virus distribution and persistence, likely via T cell crosstalk. • Microglia depletion exacerbated seizure occurrence and hippocampal and spinal cord damage. • Specific depletion of microglia helps to parse out their exact roles in viral encephalitis. Monocytes Elsevier Spinal cord Elsevier Neuroinflammation Elsevier T cells Elsevier Hippocampus Elsevier Seizures Elsevier Käufer, Christopher oth Gerhauser, Ingo oth Chhatbar, Chintan oth Ghita, Luca oth Kalinke, Ulrich oth Löscher, Wolfgang oth Enthalten in Elsevier Al Naim, Abdullah F. ELSEVIER A new poly(3,4-ethylenedioxythiophene)-poly (styrene sulfonate)/nickel oxide nanoparticles (PEDOT:PSS/NiO) thermoelectric system with a promising thermoelectric power factor 2022 Orlando, Fla. [u.a.] (DE-627)ELV008146462 volume:74 year:2018 pages:186-204 extent:19 https://doi.org/10.1016/j.bbi.2018.09.006 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 35.00 Chemie: Allgemeines VZ 51.50 Metallische Werkstoffe: Allgemeines VZ 58.00 Chemische Technik: Allgemeines VZ AR 74 2018 186-204 19 |
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10.1016/j.bbi.2018.09.006 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000001886.pica (DE-627)ELV045167702 (ELSEVIER)S0889-1591(18)30356-8 DE-627 ger DE-627 rakwb eng 540 VZ 35.00 bkl 51.50 bkl 58.00 bkl Waltl, Inken verfasserin aut Microglia have a protective role in viral encephalitis-induced seizure development and hippocampal damage 2018 19 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier • Microglia’s role in encephalitis and its long-term consequences is incompletely understood. • We studied consequences of microglia depletion in a picorna virus model of epilepsy in mice. • Data indicate that microglia limits virus distribution and persistence, likely via T cell crosstalk. • Microglia depletion exacerbated seizure occurrence and hippocampal and spinal cord damage. • Specific depletion of microglia helps to parse out their exact roles in viral encephalitis. Monocytes Elsevier Spinal cord Elsevier Neuroinflammation Elsevier T cells Elsevier Hippocampus Elsevier Seizures Elsevier Käufer, Christopher oth Gerhauser, Ingo oth Chhatbar, Chintan oth Ghita, Luca oth Kalinke, Ulrich oth Löscher, Wolfgang oth Enthalten in Elsevier Al Naim, Abdullah F. ELSEVIER A new poly(3,4-ethylenedioxythiophene)-poly (styrene sulfonate)/nickel oxide nanoparticles (PEDOT:PSS/NiO) thermoelectric system with a promising thermoelectric power factor 2022 Orlando, Fla. [u.a.] (DE-627)ELV008146462 volume:74 year:2018 pages:186-204 extent:19 https://doi.org/10.1016/j.bbi.2018.09.006 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 35.00 Chemie: Allgemeines VZ 51.50 Metallische Werkstoffe: Allgemeines VZ 58.00 Chemische Technik: Allgemeines VZ AR 74 2018 186-204 19 |
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Enthalten in A new poly(3,4-ethylenedioxythiophene)-poly (styrene sulfonate)/nickel oxide nanoparticles (PEDOT:PSS/NiO) thermoelectric system with a promising thermoelectric power factor Orlando, Fla. [u.a.] volume:74 year:2018 pages:186-204 extent:19 |
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A new poly(3,4-ethylenedioxythiophene)-poly (styrene sulfonate)/nickel oxide nanoparticles (PEDOT:PSS/NiO) thermoelectric system with a promising thermoelectric power factor |
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A new poly(3,4-ethylenedioxythiophene)-poly (styrene sulfonate)/nickel oxide nanoparticles (PEDOT:PSS/NiO) thermoelectric system with a promising thermoelectric power factor |
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2018 |
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Waltl, Inken |
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Elektronische Aufsätze |
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Waltl, Inken |
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10.1016/j.bbi.2018.09.006 |
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540 |
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microglia have a protective role in viral encephalitis-induced seizure development and hippocampal damage |
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Microglia have a protective role in viral encephalitis-induced seizure development and hippocampal damage |
| abstract |
• Microglia’s role in encephalitis and its long-term consequences is incompletely understood. • We studied consequences of microglia depletion in a picorna virus model of epilepsy in mice. • Data indicate that microglia limits virus distribution and persistence, likely via T cell crosstalk. • Microglia depletion exacerbated seizure occurrence and hippocampal and spinal cord damage. • Specific depletion of microglia helps to parse out their exact roles in viral encephalitis. |
| abstractGer |
• Microglia’s role in encephalitis and its long-term consequences is incompletely understood. • We studied consequences of microglia depletion in a picorna virus model of epilepsy in mice. • Data indicate that microglia limits virus distribution and persistence, likely via T cell crosstalk. • Microglia depletion exacerbated seizure occurrence and hippocampal and spinal cord damage. • Specific depletion of microglia helps to parse out their exact roles in viral encephalitis. |
| abstract_unstemmed |
• Microglia’s role in encephalitis and its long-term consequences is incompletely understood. • We studied consequences of microglia depletion in a picorna virus model of epilepsy in mice. • Data indicate that microglia limits virus distribution and persistence, likely via T cell crosstalk. • Microglia depletion exacerbated seizure occurrence and hippocampal and spinal cord damage. • Specific depletion of microglia helps to parse out their exact roles in viral encephalitis. |
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Microglia have a protective role in viral encephalitis-induced seizure development and hippocampal damage |
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https://doi.org/10.1016/j.bbi.2018.09.006 |
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Käufer, Christopher Gerhauser, Ingo Chhatbar, Chintan Ghita, Luca Kalinke, Ulrich Löscher, Wolfgang |
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Käufer, Christopher Gerhauser, Ingo Chhatbar, Chintan Ghita, Luca Kalinke, Ulrich Löscher, Wolfgang |
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10.1016/j.bbi.2018.09.006 |
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2024-07-06T16:47:36.683Z |
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